BR9710908A - Composição de polìmero contendo proteìna para administração oral - Google Patents

Composição de polìmero contendo proteìna para administração oral

Info

Publication number
BR9710908A
BR9710908A BR9710908-8A BR9710908A BR9710908A BR 9710908 A BR9710908 A BR 9710908A BR 9710908 A BR9710908 A BR 9710908A BR 9710908 A BR9710908 A BR 9710908A
Authority
BR
Brazil
Prior art keywords
oral administration
protein
polymer composition
containing polymer
therapeutic
Prior art date
Application number
BR9710908-8A
Other languages
English (en)
Inventor
Nikolai A Plate
Lev I Valuev
Tatyana A Valueva
Ludmilla K Staroseltseva
Alexander S Ametov
Vladimir A Knyazhev
Jay M S Henis
Original Assignee
Orex Pharmaceutical Dev Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US08/691,617 external-priority patent/US6004583A/en
Application filed by Orex Pharmaceutical Dev Corp filed Critical Orex Pharmaceutical Dev Corp
Publication of BR9710908A publication Critical patent/BR9710908A/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/42—Proteins; Polypeptides; Degradation products thereof; Derivatives thereof, e.g. albumin, gelatin or zein
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/46—Ingredients of undetermined constitution or reaction products thereof, e.g. skin, bone, milk, cotton fibre, eggshell, oxgall or plant extracts

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Inorganic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)

Abstract

"COMPOSIçãO DE POLìMERO CONTENDO PROTEìNA PARA ADMINISTRAçãO ORAL" A presente invenção refere-se a uma composição, contendo produto terapêutico, adaptada para administração oral de um material biologicamente ativo, o qual compreende um polímero insolúvel em água mas intumescível em água quimicamente modificado com um inibidor de enzima contendo uma funcionalidade química, que tem uma afinidade interativa para receptores alvo nas paredes de barreira de transporte do trato digestivo do beneficiário pretendido, e pelo menos um produto terapêutico de pouca biodisponibilidade oral.
BR9710908-8A 1996-08-02 1997-07-30 Composição de polìmero contendo proteìna para administração oral BR9710908A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/691,617 US6004583A (en) 1995-03-22 1996-08-02 Protein-containing polymer composition for oral administration
PCT/US1997/013352 WO1998005362A2 (en) 1996-08-02 1997-07-30 Protein-containing polymer composition for oral administration

Publications (1)

Publication Number Publication Date
BR9710908A true BR9710908A (pt) 2000-10-24

Family

ID=24777264

Family Applications (1)

Application Number Title Priority Date Filing Date
BR9710908-8A BR9710908A (pt) 1996-08-02 1997-07-30 Composição de polìmero contendo proteìna para administração oral

Country Status (8)

Country Link
EP (1) EP0918543B1 (pt)
AT (1) ATE264693T1 (pt)
AU (1) AU3819297A (pt)
BR (1) BR9710908A (pt)
DE (1) DE69728769T2 (pt)
DK (1) DK0918543T3 (pt)
ES (1) ES2219773T3 (pt)
WO (1) WO1998005362A2 (pt)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6645485B2 (en) * 2000-05-10 2003-11-11 Allan R. Dunn Method of treating inflammation in the joints of a body
US20080153779A1 (en) * 2005-02-01 2008-06-26 Jun Liao Gastric Retention and Controlled Release Delivery System
CN104411341A (zh) * 2012-06-15 2015-03-11 阿根塔塞有限责任公司弗利尔系统股份有限公司分公司 智能自我去污聚合物和抑制细菌及真菌生长的方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3380726D1 (en) * 1982-06-24 1989-11-23 Japan Chem Res Long-acting composition
DE3604868A1 (de) * 1986-02-15 1987-08-20 Behringwerke Ag Insulinderivate, verfahren zu ihrer herstellung und ihre verwendung
US5359030A (en) * 1993-05-10 1994-10-25 Protein Delivery, Inc. Conjugation-stabilized polypeptide compositions, therapeutic delivery and diagnostic formulations comprising same, and method of making and using the same
WO1995015352A1 (en) * 1993-12-01 1995-06-08 Universite Du Quebec A Montreal Albumin based hydrogel
RU2076733C1 (ru) * 1994-03-23 1997-04-10 Институт нефтехимического синтеза им.А.В.Топчеева РАН Способ получения производных инсулина
RU2066551C1 (ru) * 1994-03-23 1996-09-20 Институт нефтехимического синтеза РАН Способ получения инсулинсодержащих полимерных гидрогелей

Also Published As

Publication number Publication date
ATE264693T1 (de) 2004-05-15
WO1998005362A2 (en) 1998-02-12
DE69728769T2 (de) 2005-03-31
AU3819297A (en) 1998-02-25
EP0918543B1 (en) 2004-04-21
DK0918543T3 (da) 2004-07-26
WO1998005362A3 (en) 1998-05-07
ES2219773T3 (es) 2004-12-01
DE69728769D1 (de) 2004-05-27
EP0918543A2 (en) 1999-06-02

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Legal Events

Date Code Title Description
B06A Patent application procedure suspended [chapter 6.1 patent gazette]
B06A Patent application procedure suspended [chapter 6.1 patent gazette]
B11B Dismissal acc. art. 36, par 1 of ipl - no reply within 90 days to fullfil the necessary requirements
B15K Others concerning applications: alteration of classification

Ipc: A61K 47/32 (2006.01), A61K 47/42 (2017.0