ES2196381T3 - Comprimidos chupables para liberacion modificada de principios activos en el tracto gastrointestinal. - Google Patents

Comprimidos chupables para liberacion modificada de principios activos en el tracto gastrointestinal.

Info

Publication number
ES2196381T3
ES2196381T3 ES97950197T ES97950197T ES2196381T3 ES 2196381 T3 ES2196381 T3 ES 2196381T3 ES 97950197 T ES97950197 T ES 97950197T ES 97950197 T ES97950197 T ES 97950197T ES 2196381 T3 ES2196381 T3 ES 2196381T3
Authority
ES
Spain
Prior art keywords
gastrointestinal tract
chupable
tablets
modified release
active principles
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES97950197T
Other languages
English (en)
Inventor
Karsten Cremer
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
LTS Lohmann Therapie Systeme AG
Original Assignee
LTS Lohmann Therapie Systeme AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by LTS Lohmann Therapie Systeme AG filed Critical LTS Lohmann Therapie Systeme AG
Application granted granted Critical
Publication of ES2196381T3 publication Critical patent/ES2196381T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
    • A61K9/2081—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets with microcapsules or coated microparticles according to A61K9/50

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)

Abstract

SE DESCRIBE UNA TABLETA FARMACEUTICA PARA CHUPARSE CON LIBERACION MODIFICADA DE PRINCIPIOS ACTIVOS EN EL TRACTO GASTROINTESTINAL CON PARTICULAS QUE CONTIENEN LOS PRINCIPIOS ACTIVOS, LAS CUALES TIENEN UN PRIMER RECUBRIMIENTO QUE CONTROLA LA LIBERACION, Y UN SEGUNDO RECUBRIMIENTO EXTERNO CON PROPIEDADES RESISTENTES A LA SALIVA. EL PRIMER RECUBRIMIENTO, QUE CONTROLA LA LIBERACION DE LOS PRINCIPIOS ACTIVOS, PUEDE TENER PROPIEDADES DE RETARDAMIENTO O QUE SON RESISTENTES A LOS JUGOS GASTRICOS.
ES97950197T 1996-11-23 1997-11-17 Comprimidos chupables para liberacion modificada de principios activos en el tracto gastrointestinal. Expired - Lifetime ES2196381T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19648576A DE19648576C2 (de) 1996-11-23 1996-11-23 Lutschtablette zur modifizierten Freisetzung von Wirkstoffen im Gastrointestinaltrakt

Publications (1)

Publication Number Publication Date
ES2196381T3 true ES2196381T3 (es) 2003-12-16

Family

ID=7812582

Family Applications (1)

Application Number Title Priority Date Filing Date
ES97950197T Expired - Lifetime ES2196381T3 (es) 1996-11-23 1997-11-17 Comprimidos chupables para liberacion modificada de principios activos en el tracto gastrointestinal.

Country Status (11)

Country Link
US (1) US6270798B2 (es)
EP (1) EP0941070B1 (es)
JP (1) JP2001527526A (es)
KR (1) KR100429489B1 (es)
AT (1) ATE235232T1 (es)
AU (1) AU725493B2 (es)
CA (1) CA2272442C (es)
DE (2) DE19648576C2 (es)
ES (1) ES2196381T3 (es)
NO (1) NO992477L (es)
WO (1) WO1998023262A2 (es)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19849848A1 (de) * 1998-10-29 2000-05-04 Lohmann Therapie Syst Lts Oral applizierbare, mit Flüssigkeit spontan zerfallende therapeutische Darreichungsform und Verfahren zu ihrer Herstellung
DE19933148A1 (de) * 1999-07-20 2001-01-25 Boehringer Ingelheim Int Ambroxolhaltige Lutschtablette
US20060251722A1 (en) * 2005-05-03 2006-11-09 Novavax, Inc. Multi-component vitamin and mineral supplement for the optimal absorption of components
JP2013501068A (ja) 2009-08-05 2013-01-10 アイディニックス ファーマシューティカルズ インコーポレイテッド 大環状セリンプロテアーゼ阻害剤
WO2011056764A1 (en) 2009-11-05 2011-05-12 Ambit Biosciences Corp. Isotopically enriched or fluorinated imidazo[2,1-b][1,3]benzothiazoles
NZ600608A (en) 2009-12-18 2015-01-30 Idenix Pharmaceuticals Inc 5,5-fused arylene or heteroarylene hepatitis c virus inhibitors
ES2836811T3 (es) * 2010-01-15 2021-06-28 Kemin Ind Zhuhai Co Ltd Alfa-amilasa protegida
WO2011094890A1 (en) 2010-02-02 2011-08-11 Argusina Inc. Phenylalanine derivatives and their use as non-peptide glp-1 receptor modulators
WO2011112689A2 (en) 2010-03-11 2011-09-15 Ambit Biosciences Corp. Saltz of an indazolylpyrrolotriazine
CA2809993A1 (en) 2010-09-01 2012-03-08 Ambit Biosciences Corporation An optically active pyrazolylaminoquinazoline, and pharmaceutical compositions and methods of use thereof
MX2013002383A (es) 2010-09-01 2013-07-05 Ambit Biosciences Corp Sales bromhidrato de una pirazolilaminoquinazolina.
US20140079686A1 (en) 2010-12-06 2014-03-20 Shikha P. Barman Methods For Treating Baldness And Promoting Hair Growth
WO2012080050A1 (en) 2010-12-14 2012-06-21 F. Hoffmann-La Roche Ag Solid forms of a phenoxybenzenesulfonyl compound
WO2012106299A1 (en) 2011-01-31 2012-08-09 Celgene Corporation Pharmaceutical compositions of cytidine analogs and methods of use thereof
AR085352A1 (es) 2011-02-10 2013-09-25 Idenix Pharmaceuticals Inc Inhibidores macrociclicos de serina proteasa, sus composiciones farmaceuticas y su uso para tratar infecciones por hcv
US20120252721A1 (en) 2011-03-31 2012-10-04 Idenix Pharmaceuticals, Inc. Methods for treating drug-resistant hepatitis c virus infection with a 5,5-fused arylene or heteroarylene hepatitis c virus inhibitor
KR20140138293A (ko) 2012-03-16 2014-12-03 액시킨 파마수티컬스 인코포레이티드 3,5-다이아미노피라졸 키나아제 억제제
EP2833880B1 (en) * 2012-04-02 2017-08-23 Pharma Seeds Create, LLC Ibuprofen solid oral dosage composition comprising a methacrylic acid copolymer
NZ631142A (en) 2013-09-18 2016-03-31 Axikin Pharmaceuticals Inc Pharmaceutically acceptable salts of 3,5-diaminopyrazole kinase inhibitors
US20160229866A1 (en) 2013-09-20 2016-08-11 Idenix Pharmaceuticals Inc. Hepatitis c virus inhibitors
US20150174079A1 (en) * 2013-12-24 2015-06-25 Food for Health International, LLC Lozenges with silver nanoparticles
WO2015134560A1 (en) 2014-03-05 2015-09-11 Idenix Pharmaceuticals, Inc. Solid forms of a flaviviridae virus inhibitor compound and salts thereof
CA2943231C (en) 2014-03-20 2023-10-24 Capella Therapeutics, Inc. Benzimidazole derivatives as erbb tyrosine kinase inhibitors for the treatment of cancer
PT3119762T (pt) 2014-03-20 2021-08-31 Capella Therapeutics Inc Derivados de benzimidazole como inibidores de tirosina quinase erbb para o tratamento do cancro
MY191736A (en) 2014-12-23 2022-07-13 Axikin Pharmaceuticals Inc 3,5-diaminopyrazole kinase inhibitors

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2565107B1 (fr) 1984-05-30 1986-09-05 Ucb Laboratoires Nouveau medicament a base de charbon actif et son procede de preparation
DE3678641D1 (de) * 1985-08-16 1991-05-16 Procter & Gamble Partikel mit konstanter wirkstofffreisetzung.
US4786508A (en) * 1986-05-30 1988-11-22 Warner-Lambert Company Coated dosage forms
US4800087A (en) * 1986-11-24 1989-01-24 Mehta Atul M Taste-masked pharmaceutical compositions
JPS63258809A (ja) * 1987-04-16 1988-10-26 Towa Yakuhin Kk 医薬活性成分の放出性にすぐれ、かつ苦味を隠蔽した細粒剤
JP2573969B2 (ja) * 1987-10-21 1997-01-22 帝國製薬株式会社 薬物断続放出性口腔内適用製剤
IT1256651B (it) * 1992-12-11 1995-12-12 Giancarlo Santus Composizione farmaceutica a rilascio controllato in sospensione liquida
WO1991015194A1 (en) * 1990-04-11 1991-10-17 The Upjohn Company Taste masking of ibuprofen by fluid bed coating
IT1246383B (it) * 1990-04-17 1994-11-18 Eurand Int Metodo per il mascheramento del sapore di farmaci
US5460825A (en) * 1990-05-23 1995-10-24 Mcneil-Ppc, Inc. Taste mask coatings for preparing chewable pharmaceutical tablets
WO1991019486A1 (en) * 1990-06-14 1991-12-26 Kalmo Enterprises, Inc. Stable aqueous drug suspensions
US5464632C1 (en) * 1991-07-22 2001-02-20 Prographarm Lab Rapidly disintegratable multiparticular tablet
CA2137265C (en) * 1992-06-04 2003-10-28 Sanjay Bhardwaj Palatable pharmaceutical compositions
DE4333190C2 (de) * 1993-09-29 1996-05-30 Korsatko Werner Univ Prof Dr E Zerbeißtablette mit verzögerter Wirkstoff-Freisetzung

Also Published As

Publication number Publication date
WO1998023262A2 (de) 1998-06-04
WO1998023262A3 (de) 1998-09-11
KR20000057205A (ko) 2000-09-15
CA2272442C (en) 2004-05-11
NO992477D0 (no) 1999-05-21
EP0941070B1 (de) 2003-03-26
JP2001527526A (ja) 2001-12-25
AU5322598A (en) 1998-06-22
ATE235232T1 (de) 2003-04-15
US20010001668A1 (en) 2001-05-24
KR100429489B1 (ko) 2004-05-03
DE19648576C2 (de) 1999-08-12
CA2272442A1 (en) 1998-06-04
US6270798B2 (en) 2001-08-07
AU725493B2 (en) 2000-10-12
EP0941070A2 (de) 1999-09-15
DE19648576A1 (de) 1998-06-04
NO992477L (no) 1999-05-21
DE59709645D1 (de) 2003-04-30

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