ES2196381T3 - Comprimidos chupables para liberacion modificada de principios activos en el tracto gastrointestinal. - Google Patents

Comprimidos chupables para liberacion modificada de principios activos en el tracto gastrointestinal.

Info

Publication number
ES2196381T3
ES2196381T3 ES97950197T ES97950197T ES2196381T3 ES 2196381 T3 ES2196381 T3 ES 2196381T3 ES 97950197 T ES97950197 T ES 97950197T ES 97950197 T ES97950197 T ES 97950197T ES 2196381 T3 ES2196381 T3 ES 2196381T3
Authority
ES
Spain
Prior art keywords
gastrointestinal tract
chupable
tablets
modified release
active principles
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES97950197T
Other languages
English (en)
Inventor
Karsten Cremer
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
LTS Lohmann Therapie Systeme AG
Original Assignee
LTS Lohmann Therapie Systeme AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by LTS Lohmann Therapie Systeme AG filed Critical LTS Lohmann Therapie Systeme AG
Application granted granted Critical
Publication of ES2196381T3 publication Critical patent/ES2196381T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
    • A61K9/2081—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets with microcapsules or coated microparticles according to A61K9/50

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)

Abstract

SE DESCRIBE UNA TABLETA FARMACEUTICA PARA CHUPARSE CON LIBERACION MODIFICADA DE PRINCIPIOS ACTIVOS EN EL TRACTO GASTROINTESTINAL CON PARTICULAS QUE CONTIENEN LOS PRINCIPIOS ACTIVOS, LAS CUALES TIENEN UN PRIMER RECUBRIMIENTO QUE CONTROLA LA LIBERACION, Y UN SEGUNDO RECUBRIMIENTO EXTERNO CON PROPIEDADES RESISTENTES A LA SALIVA. EL PRIMER RECUBRIMIENTO, QUE CONTROLA LA LIBERACION DE LOS PRINCIPIOS ACTIVOS, PUEDE TENER PROPIEDADES DE RETARDAMIENTO O QUE SON RESISTENTES A LOS JUGOS GASTRICOS.
ES97950197T 1996-11-23 1997-11-17 Comprimidos chupables para liberacion modificada de principios activos en el tracto gastrointestinal. Expired - Lifetime ES2196381T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19648576A DE19648576C2 (de) 1996-11-23 1996-11-23 Lutschtablette zur modifizierten Freisetzung von Wirkstoffen im Gastrointestinaltrakt

Publications (1)

Publication Number Publication Date
ES2196381T3 true ES2196381T3 (es) 2003-12-16

Family

ID=7812582

Family Applications (1)

Application Number Title Priority Date Filing Date
ES97950197T Expired - Lifetime ES2196381T3 (es) 1996-11-23 1997-11-17 Comprimidos chupables para liberacion modificada de principios activos en el tracto gastrointestinal.

Country Status (11)

Country Link
US (1) US6270798B2 (es)
EP (1) EP0941070B1 (es)
JP (1) JP2001527526A (es)
KR (1) KR100429489B1 (es)
AT (1) ATE235232T1 (es)
AU (1) AU725493B2 (es)
CA (1) CA2272442C (es)
DE (2) DE19648576C2 (es)
ES (1) ES2196381T3 (es)
NO (1) NO992477D0 (es)
WO (1) WO1998023262A2 (es)

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DE19849848A1 (de) * 1998-10-29 2000-05-04 Lohmann Therapie Syst Lts Oral applizierbare, mit Flüssigkeit spontan zerfallende therapeutische Darreichungsform und Verfahren zu ihrer Herstellung
DE19933148A1 (de) * 1999-07-20 2001-01-25 Boehringer Ingelheim Int Ambroxolhaltige Lutschtablette
US20060251722A1 (en) * 2005-05-03 2006-11-09 Novavax, Inc. Multi-component vitamin and mineral supplement for the optimal absorption of components
TW201117812A (en) 2009-08-05 2011-06-01 Idenix Pharmaceuticals Inc Macrocyclic serine protease inhibitors
WO2011056764A1 (en) 2009-11-05 2011-05-12 Ambit Biosciences Corp. Isotopically enriched or fluorinated imidazo[2,1-b][1,3]benzothiazoles
MX2012006877A (es) 2009-12-18 2012-08-31 Idenix Pharmaceuticals Inc Inhibidores de virus de hepatitis c de arileno o heteroarileno 5, 5 - fusionado.
CN103118547A (zh) * 2010-01-15 2013-05-22 凯敏工业公司 受保护的α-淀粉酶
WO2011094890A1 (en) 2010-02-02 2011-08-11 Argusina Inc. Phenylalanine derivatives and their use as non-peptide glp-1 receptor modulators
WO2011112689A2 (en) 2010-03-11 2011-09-15 Ambit Biosciences Corp. Saltz of an indazolylpyrrolotriazine
AU2011296046B2 (en) 2010-09-01 2015-05-14 Ambit Biosciences Corporation Hydrobromide salts of a pyrazolylaminoquinazoline
ES2579942T3 (es) 2010-09-01 2016-08-17 Ambit Biosciences Corporation Pirazolilaminoquinazolina ópticamente activa y composiciones farmacéuticas y métodos de uso de la misma
BR112013014021A8 (pt) 2010-12-06 2017-10-03 Follica Inc Métodos para tratamento de calvície e promoção de crescimento de cabelos
WO2012080050A1 (en) 2010-12-14 2012-06-21 F. Hoffmann-La Roche Ag Solid forms of a phenoxybenzenesulfonyl compound
MX2013006020A (es) 2011-01-31 2013-10-01 Celgene Corp Composicion farmaceutica de analogos de citidina y metodos para su uso.
WO2012109398A1 (en) 2011-02-10 2012-08-16 Idenix Pharmaceuticals, Inc. Macrocyclic serine protease inhibitors, pharmaceutical compositions thereof, and their use for treating hcv infections
US20120252721A1 (en) 2011-03-31 2012-10-04 Idenix Pharmaceuticals, Inc. Methods for treating drug-resistant hepatitis c virus infection with a 5,5-fused arylene or heteroarylene hepatitis c virus inhibitor
RU2014141674A (ru) 2012-03-16 2016-05-10 Аксикин Фармасьютикалз, Инк. 3,5-диаминопиразоловые ингибиторы киназы
WO2013151754A1 (en) * 2012-04-02 2013-10-10 Teikoku Pharma Usa, Inc. Ibuprofen solid oral dosage composition comprising a methacrylic acid copolymer
NZ631142A (en) 2013-09-18 2016-03-31 Axikin Pharmaceuticals Inc Pharmaceutically acceptable salts of 3,5-diaminopyrazole kinase inhibitors
EP3046924A1 (en) 2013-09-20 2016-07-27 IDENIX Pharmaceuticals, Inc. Hepatitis c virus inhibitors
US20150174079A1 (en) * 2013-12-24 2015-06-25 Food for Health International, LLC Lozenges with silver nanoparticles
WO2015134560A1 (en) 2014-03-05 2015-09-11 Idenix Pharmaceuticals, Inc. Solid forms of a flaviviridae virus inhibitor compound and salts thereof
RU2021101430A (ru) 2014-03-20 2021-03-16 Капелла Терапьютикс, Инк. Производные бензимидазола как ингибиторы тирозинкиназ erbb для лечения рака
AU2015231215B2 (en) 2014-03-20 2019-07-18 Capella Therapeutics, Inc. Benzimidazole derivatives as ERBB tyrosine kinase inhibitors for the treatment of cancer
KR102034202B1 (ko) 2014-12-23 2019-10-18 에스엠에이 세라퓨틱스 아이엔씨. 3,5-디아미노피라졸 키나제 억제제

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2565107B1 (fr) 1984-05-30 1986-09-05 Ucb Laboratoires Nouveau medicament a base de charbon actif et son procede de preparation
EP0212745B1 (en) 1985-08-16 1991-04-10 The Procter & Gamble Company Drug particles having constant release
US4786508A (en) * 1986-05-30 1988-11-22 Warner-Lambert Company Coated dosage forms
US4800087A (en) * 1986-11-24 1989-01-24 Mehta Atul M Taste-masked pharmaceutical compositions
JPS63258809A (ja) * 1987-04-16 1988-10-26 Towa Yakuhin Kk 医薬活性成分の放出性にすぐれ、かつ苦味を隠蔽した細粒剤
JP2573969B2 (ja) * 1987-10-21 1997-01-22 帝國製薬株式会社 薬物断続放出性口腔内適用製剤
IT1256651B (it) * 1992-12-11 1995-12-12 Giancarlo Santus Composizione farmaceutica a rilascio controllato in sospensione liquida
EP0524180B1 (en) * 1990-04-11 1995-04-26 The Upjohn Company Taste masking of ibuprofen by fluid bed coating
IT1246383B (it) * 1990-04-17 1994-11-18 Eurand Int Metodo per il mascheramento del sapore di farmaci
US5460825A (en) * 1990-05-23 1995-10-24 Mcneil-Ppc, Inc. Taste mask coatings for preparing chewable pharmaceutical tablets
AU8219191A (en) * 1990-06-14 1992-01-07 Kalmo Enterprises, Inc. Stable aqueous drug suspensions
US5464632C1 (en) * 1991-07-22 2001-02-20 Prographarm Lab Rapidly disintegratable multiparticular tablet
ATE217789T1 (de) * 1992-06-04 2002-06-15 Smithkline Beecham Corp Angenehm schmeckende pharmazeutische zusammensetzungen
DE4333190C2 (de) * 1993-09-29 1996-05-30 Korsatko Werner Univ Prof Dr E Zerbeißtablette mit verzögerter Wirkstoff-Freisetzung

Also Published As

Publication number Publication date
KR100429489B1 (ko) 2004-05-03
WO1998023262A3 (de) 1998-09-11
NO992477L (no) 1999-05-21
NO992477D0 (no) 1999-05-21
EP0941070A2 (de) 1999-09-15
EP0941070B1 (de) 2003-03-26
AU725493B2 (en) 2000-10-12
ATE235232T1 (de) 2003-04-15
US6270798B2 (en) 2001-08-07
US20010001668A1 (en) 2001-05-24
KR20000057205A (ko) 2000-09-15
DE59709645D1 (de) 2003-04-30
JP2001527526A (ja) 2001-12-25
DE19648576C2 (de) 1999-08-12
DE19648576A1 (de) 1998-06-04
WO1998023262A2 (de) 1998-06-04
CA2272442C (en) 2004-05-11
CA2272442A1 (en) 1998-06-04
AU5322598A (en) 1998-06-22

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