ATE306910T1 - Tablette mit verlängerter wirkstoffabgabe im magen - Google Patents

Tablette mit verlängerter wirkstoffabgabe im magen

Info

Publication number
ATE306910T1
ATE306910T1 AT98401956T AT98401956T ATE306910T1 AT E306910 T1 ATE306910 T1 AT E306910T1 AT 98401956 T AT98401956 T AT 98401956T AT 98401956 T AT98401956 T AT 98401956T AT E306910 T1 ATE306910 T1 AT E306910T1
Authority
AT
Austria
Prior art keywords
stomach
tablet
extended release
granules
drug
Prior art date
Application number
AT98401956T
Other languages
English (en)
Inventor
Yves Bonhomme
Geoffroy Nicholson
Original Assignee
Merck Sante Sas
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck Sante Sas filed Critical Merck Sante Sas
Application granted granted Critical
Publication of ATE306910T1 publication Critical patent/ATE306910T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0065—Forms with gastric retention, e.g. floating on gastric juice, adhering to gastric mucosa, expanding to prevent passage through the pylorus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/155—Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
    • A61K9/2081—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets with microcapsules or coated microparticles according to A61K9/50

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
AT98401956T 1998-07-30 1998-07-30 Tablette mit verlängerter wirkstoffabgabe im magen ATE306910T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP98401956A EP0976395B1 (de) 1998-07-30 1998-07-30 Tablette mit verlängerter Wirkstoffabgabe im Magen

Publications (1)

Publication Number Publication Date
ATE306910T1 true ATE306910T1 (de) 2005-11-15

Family

ID=8235460

Family Applications (1)

Application Number Title Priority Date Filing Date
AT98401956T ATE306910T1 (de) 1998-07-30 1998-07-30 Tablette mit verlängerter wirkstoffabgabe im magen

Country Status (8)

Country Link
EP (1) EP0976395B1 (de)
AT (1) ATE306910T1 (de)
AU (1) AU5731899A (de)
DE (1) DE69831940T2 (de)
DK (1) DK0976395T3 (de)
ES (1) ES2249816T3 (de)
SI (1) SI0976395T1 (de)
WO (1) WO2000006129A1 (de)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1510208A1 (de) 2003-08-22 2005-03-02 Fournier Laboratories Ireland Limited Metformin-Statin-Kombination enthaltende pharmazeutische Zusammensetzungen
ES2247897B1 (es) * 2003-12-18 2007-05-01 Gat Formulation Gmbh Tabletas con matriz polimerica emulsionada para emision controlada de gases y procedimiento para su fabricacion.
WO2005060942A1 (en) * 2003-12-19 2005-07-07 Aurobindo Pharma Ltd Extended release pharmaceutical composition of metformin
DE102004042139B4 (de) * 2004-08-31 2009-06-10 Aristocon Verwaltungs- Gmbh Perorale Darreichungsformen zur Erzielung eines Retardierungseffektes nach der Arzneimitteleinnahme mit einer Mahlzeit
AU2006290352B2 (en) * 2005-08-30 2012-06-07 Abbott Healthcare Private Limited Extended release pharmaceutical composition of metformin and a process for producing it
WO2007038979A1 (en) * 2005-09-22 2007-04-12 Swissco Development Ag Effervescent metformin composition and tablets and granules made therefrom
IL210279A0 (en) 2009-12-25 2011-03-31 Dexcel Pharma Technologies Ltd Extended release compositions for high solubility, high permeability acdtive pharmaceutical ingredients
EP2361615A1 (de) 2010-02-19 2011-08-31 Alfred E. Tiefenbacher GmbH & Co. KG Tablette mit verlängerter Dipyridamolfreisetzung
US8581001B2 (en) 2010-04-16 2013-11-12 Codman & Shurtleff Metformin-cysteine prodrug
WO2013115746A1 (en) * 2012-01-31 2013-08-08 Mahmut Bilgic A production method for (effervescent) pharmaceutical compositions comprising an alpha - glucosidase inhibitor (miglitol) and metformin
WO2013115745A1 (en) * 2012-01-31 2013-08-08 Mahmut Bilgic A process for production of pharmaceutical (effervescent) composition comprising alpha - glucosidase inhibitor (e.g. vogliobose and metformin)
DE102014008685A1 (de) * 2014-06-13 2015-12-17 Lorenz Meinel Freisetzungssystem für therapeutisches Gas
WO2019183470A2 (en) 2018-03-22 2019-09-26 Incarda Therapeutics, Inc. A novel method to slow ventricular rate

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS62195323A (ja) * 1986-02-24 1987-08-28 Eisai Co Ltd 胃内滞留型粒子
FR2611500B1 (fr) * 1987-03-06 1990-05-04 Lipha Emploi de derives du biguanide dans la preparation de medicaments
GB9010039D0 (en) * 1990-05-03 1990-06-27 Reckitt & Colmann Prod Ltd Medicament preparation

Also Published As

Publication number Publication date
DE69831940T2 (de) 2006-04-20
EP0976395B1 (de) 2005-10-19
AU5731899A (en) 2000-02-21
SI0976395T1 (sl) 2006-04-30
EP0976395A1 (de) 2000-02-02
DK0976395T3 (da) 2005-11-14
ES2249816T3 (es) 2006-04-01
DE69831940D1 (de) 2006-03-02
WO2000006129A1 (en) 2000-02-10

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