BR9710597A - P¡rano¡ndol e carbazol inib¡dores de cox-2 - Google Patents
P¡rano¡ndol e carbazol inib¡dores de cox-2Info
- Publication number
- BR9710597A BR9710597A BR9710597A BR9710597A BR9710597A BR 9710597 A BR9710597 A BR 9710597A BR 9710597 A BR9710597 A BR 9710597A BR 9710597 A BR9710597 A BR 9710597A BR 9710597 A BR9710597 A BR 9710597A
- Authority
- BR
- Brazil
- Prior art keywords
- ndol
- rano
- cox
- carbazole
- inhibitors
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
- C07D491/044—Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring
- C07D491/052—Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring the oxygen-containing ring being six-membered
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/407—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with other heterocyclic ring systems, e.g. ketorolac, physostigmine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/56—Ring systems containing three or more rings
- C07D209/80—[b, c]- or [b, d]-condensed
- C07D209/82—Carbazoles; Hydrogenated carbazoles
- C07D209/88—Carbazoles; Hydrogenated carbazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the ring system
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US68784996A | 1996-07-26 | 1996-07-26 | |
| PCT/US1997/012782 WO1998004527A1 (en) | 1996-07-26 | 1997-07-22 | Pyranoindole and carbazole inhibitors of cox-2 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR9710597A true BR9710597A (pt) | 1999-08-17 |
Family
ID=24762121
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR9710597A BR9710597A (pt) | 1996-07-26 | 1997-07-22 | P¡rano¡ndol e carbazol inib¡dores de cox-2 |
Country Status (13)
| Country | Link |
|---|---|
| EP (1) | EP0923552A1 (pt) |
| JP (1) | JP2000515887A (pt) |
| KR (1) | KR20000029545A (pt) |
| CN (1) | CN1230948A (pt) |
| AR (1) | AR008006A1 (pt) |
| AU (1) | AU4043397A (pt) |
| BR (1) | BR9710597A (pt) |
| CA (1) | CA2261588A1 (pt) |
| HU (1) | HUP9904054A2 (pt) |
| IL (1) | IL128031A0 (pt) |
| NZ (1) | NZ334320A (pt) |
| WO (1) | WO1998004527A1 (pt) |
| ZA (1) | ZA976611B (pt) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2000002555A1 (en) * | 1998-07-09 | 2000-01-20 | Nardella Francis A | Methods and compositions for the treatment of chronic lymphocytic leukemia |
| JP4354984B2 (ja) | 2003-05-07 | 2009-10-28 | オステオロジックス エイ／エス | 水溶性ストロンチウム塩を用いる軟骨／骨症状の治療 |
| GB2422828A (en) * | 2005-02-03 | 2006-08-09 | Hunter Fleming Ltd | Tricyclic cytoprotective compounds comprising an indole residue |
| GB0522908D0 (en) | 2005-11-10 | 2005-12-21 | Merck Sharp & Dohme | Therapeutic agents |
| WO2012142256A2 (en) * | 2011-04-12 | 2012-10-18 | The Regents Of The University Of California | Modulators of mitochondrial protein import |
| WO2022195579A1 (en) | 2021-03-15 | 2022-09-22 | Saul Yedgar | Hyaluronic acid-conjugated dipalmitoyl phosphatidyl ethanolamine in combination with non-steroidal anti-inflammatory drugs (nsaids) for treating or alleviating inflammatory diseases |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4686213A (en) * | 1986-08-15 | 1987-08-11 | American Home Products Corporation | Substituted 1,3,4,9-tetrahydropyrano(3,4-b)indole-1-acetic acids |
| US4927842A (en) * | 1989-09-29 | 1990-05-22 | American Home Products Corporation | 2,3,4,9-tetrahydro-1H-carbazole acetic acid derivatives, composition and use as anti-inflammatories |
-
1997
- 1997-07-22 EP EP97938009A patent/EP0923552A1/en not_active Withdrawn
- 1997-07-22 CN CN97197994A patent/CN1230948A/zh active Pending
- 1997-07-22 KR KR1019997000603A patent/KR20000029545A/ko not_active Application Discontinuation
- 1997-07-22 IL IL12803197A patent/IL128031A0/xx unknown
- 1997-07-22 WO PCT/US1997/012782 patent/WO1998004527A1/en not_active Application Discontinuation
- 1997-07-22 BR BR9710597A patent/BR9710597A/pt not_active Application Discontinuation
- 1997-07-22 AU AU40433/97A patent/AU4043397A/en not_active Abandoned
- 1997-07-22 JP JP10508916A patent/JP2000515887A/ja active Pending
- 1997-07-22 CA CA002261588A patent/CA2261588A1/en not_active Abandoned
- 1997-07-22 NZ NZ334320A patent/NZ334320A/en unknown
- 1997-07-22 HU HU9904054A patent/HUP9904054A2/hu unknown
- 1997-07-24 ZA ZA976611A patent/ZA976611B/xx unknown
- 1997-07-25 AR ARP970103390A patent/AR008006A1/es unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CN1230948A (zh) | 1999-10-06 |
| HUP9904054A2 (hu) | 2000-04-28 |
| KR20000029545A (ko) | 2000-05-25 |
| WO1998004527A1 (en) | 1998-02-05 |
| AR008006A1 (es) | 1999-11-24 |
| CA2261588A1 (en) | 1998-02-05 |
| ZA976611B (en) | 1999-01-25 |
| IL128031A0 (en) | 1999-11-30 |
| JP2000515887A (ja) | 2000-11-28 |
| AU4043397A (en) | 1998-02-20 |
| NZ334320A (en) | 1999-10-28 |
| EP0923552A1 (en) | 1999-06-23 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FA10 | Dismissal: dismissal - article 33 of industrial property law | ||
| B11Y | Definitive dismissal - extension of time limit for request of examination expired [chapter 11.1.1 patent gazette] |