BR9707638A - Particula contendo lipìdeos, escolhidas dentre iscoms e matriz de iscoms, e, preparacao de vacina para profilaxia e/ou imunoterapia. - Google Patents
Particula contendo lipìdeos, escolhidas dentre iscoms e matriz de iscoms, e, preparacao de vacina para profilaxia e/ou imunoterapia.Info
- Publication number
- BR9707638A BR9707638A BR9707638-4A BR9707638A BR9707638A BR 9707638 A BR9707638 A BR 9707638A BR 9707638 A BR9707638 A BR 9707638A BR 9707638 A BR9707638 A BR 9707638A
- Authority
- BR
- Brazil
- Prior art keywords
- iscoms
- chosen
- pct
- immunotherapy
- prophylaxis
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/69—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
- A61K47/6901—Conjugates being cells, cell fragments, viruses, ghosts, red blood cells or viral vectors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/69—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
- A61K47/6905—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit the form being a colloid or an emulsion
- A61K47/6907—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit the form being a colloid or an emulsion the form being a microemulsion, nanoemulsion or micelle
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55577—Saponins; Quil A; QS21; ISCOMS
Abstract
"PARTìCULA CONTENDO LIPìDEOS, ESCOLHIDAS DENTRE ISCOMS E MATRIZ DE ISCOMS, E, PREPARAçãO DE VACINA PARA PROFILAXIA E/OU IMUNOTERAPIA". As partículas contendo lipídeos como iscoms, matriz de iscoms, ou vesículas, como micelas ou lipossomas que compreendem uma ou mais moléculas de receptor hidrófobo para marcação e substâncias antigênicas, cujas moléculas de receptor foram integradas na partículas e são escolhidas dentre receptores contendo lipídeos ou receptores que são hidrófobos, cujas moléculas de receptor se ligam às substâncias antigênicas.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
SE9600648A SE9600648D0 (sv) | 1996-02-21 | 1996-02-21 | Receptorbimdande enhet |
PCT/SE1997/000287 WO1997030726A1 (en) | 1996-02-21 | 1997-02-20 | Iscom or iscom-matrix comprising hydrophobic receptor molecules for antigenic substances |
Publications (1)
Publication Number | Publication Date |
---|---|
BR9707638A true BR9707638A (pt) | 2000-01-04 |
Family
ID=20401482
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR9707638-4A BR9707638A (pt) | 1996-02-21 | 1997-02-20 | Particula contendo lipìdeos, escolhidas dentre iscoms e matriz de iscoms, e, preparacao de vacina para profilaxia e/ou imunoterapia. |
Country Status (12)
Country | Link |
---|---|
US (1) | US6027732A (pt) |
EP (1) | EP0944397B1 (pt) |
AT (1) | ATE258066T1 (pt) |
AU (1) | AU718443B2 (pt) |
BR (1) | BR9707638A (pt) |
CA (1) | CA2247103C (pt) |
DE (1) | DE69727314T2 (pt) |
DK (1) | DK0944397T3 (pt) |
ES (1) | ES2214608T3 (pt) |
NZ (1) | NZ331418A (pt) |
SE (1) | SE9600648D0 (pt) |
WO (1) | WO1997030726A1 (pt) |
Families Citing this family (27)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6207646B1 (en) | 1994-07-15 | 2001-03-27 | University Of Iowa Research Foundation | Immunostimulatory nucleic acid molecules |
US20030026782A1 (en) * | 1995-02-07 | 2003-02-06 | Arthur M. Krieg | Immunomodulatory oligonucleotides |
US6406705B1 (en) * | 1997-03-10 | 2002-06-18 | University Of Iowa Research Foundation | Use of nucleic acids containing unmethylated CpG dinucleotide as an adjuvant |
US20030022854A1 (en) | 1998-06-25 | 2003-01-30 | Dow Steven W. | Vaccines using nucleic acid-lipid complexes |
US6693086B1 (en) * | 1998-06-25 | 2004-02-17 | National Jewish Medical And Research Center | Systemic immune activation method using nucleic acid-lipid complexes |
ES2572834T3 (es) * | 1999-02-17 | 2016-06-02 | Csl Limited | Complejos inmunogénicos y métodos relacionados con los mismos |
NZ518999A (en) * | 1999-11-19 | 2002-12-20 | Csl Ltd | Vaccine compositions |
SE0003538D0 (sv) * | 2000-09-29 | 2000-09-29 | Isconova Ab | New immunogenic complex |
US7713942B2 (en) * | 2001-04-04 | 2010-05-11 | Nordic Vaccine Technology A/S | Cage-like microparticle complexes comprising sterols and saponins for delivery of polynucleotides |
US20030138434A1 (en) * | 2001-08-13 | 2003-07-24 | Campbell Robert L. | Agents for enhancing the immune response |
US20050226894A1 (en) * | 2002-01-15 | 2005-10-13 | Jensen-Jarolim Erika | Oral vaccination |
EP1608403A2 (en) * | 2003-04-02 | 2005-12-28 | Coley Pharmaceutical Group, Ltd. | Immunostimulatory nucleic acid oil-in-water formulations for topical application |
US20050013812A1 (en) * | 2003-07-14 | 2005-01-20 | Dow Steven W. | Vaccines using pattern recognition receptor-ligand:lipid complexes |
TWI235440B (en) * | 2004-03-31 | 2005-07-01 | Advanced Semiconductor Eng | Method for making leadless semiconductor package |
KR100958505B1 (ko) * | 2004-07-18 | 2010-05-17 | 씨에스엘 리미티드 | 면역자극 복합체 및 향상된 인터페론-감마 반응을 유도하기위한 올리고뉴클레오티드 제제 |
PL2486938T3 (pl) | 2006-09-26 | 2018-08-31 | Infectious Disease Research Institute | Kompozycja szczepionki zawierająca syntetyczny adiuwant |
US20090181078A1 (en) * | 2006-09-26 | 2009-07-16 | Infectious Disease Research Institute | Vaccine composition containing synthetic adjuvant |
ES2325243B1 (es) * | 2008-02-27 | 2011-05-04 | Universidad De Granada | Antigeno recombinante. |
ES2606563T3 (es) | 2009-06-05 | 2017-03-24 | Infectious Disease Research Institute | Adyuvantes lipídicos de glucopiranosilo sintéticos y composiciones de vacuna que contienen los mismos |
EP2694099B1 (en) | 2011-04-08 | 2019-10-16 | Immune Design Corp. | Immunogenic compositions and methods of using the compositions for inducing humoral and cellular immune responses |
LT2811981T (lt) | 2012-02-07 | 2019-06-10 | Infectious Disease Research Institute | Pagerintos adjuvanto kompozicijos, apimančios tlr4 agonistus, ir jų panaudojimo būdai |
PL2850431T3 (pl) | 2012-05-16 | 2018-09-28 | Immune Design Corp. | Szczepionki przeciwko HSV-2 |
SG11201508092YA (en) | 2013-04-18 | 2015-10-29 | Immune Design Corp | Gla monotherapy for use in cancer treatment |
US9463198B2 (en) | 2013-06-04 | 2016-10-11 | Infectious Disease Research Institute | Compositions and methods for reducing or preventing metastasis |
EA201691348A1 (ru) | 2013-12-31 | 2016-11-30 | Инфекшес Дизиз Рисерч Инститьют | Однофлаконные вакцинные составы |
CA3141577A1 (en) | 2019-05-25 | 2020-12-03 | Infectious Disease Research Institute | Composition and method for spray drying an adjuvant vaccine emulsion |
EP4058581A1 (en) | 2019-11-15 | 2022-09-21 | Infectious Disease Research Institute | Rig-i agonist and adjuvant formulation for tumor treatment |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2403081A1 (fr) * | 1977-09-19 | 1979-04-13 | Merieux Inst | Nouveau materiau particulaire, sa preparation et son application, notamment comme medicament |
US5178860A (en) * | 1989-09-01 | 1993-01-12 | Coopers Animal Health Limited | Adjuvant complexes and vaccine made therefrom |
NL9002314A (nl) * | 1990-10-23 | 1992-05-18 | Nederlanden Staat | Immunogene complexen, in het bijzonder iscoms. |
-
1996
- 1996-02-21 SE SE9600648A patent/SE9600648D0/xx unknown
-
1997
- 1997-02-20 AU AU22383/97A patent/AU718443B2/en not_active Expired
- 1997-02-20 AT AT97905539T patent/ATE258066T1/de not_active IP Right Cessation
- 1997-02-20 DE DE1997627314 patent/DE69727314T2/de not_active Expired - Lifetime
- 1997-02-20 US US09/125,588 patent/US6027732A/en not_active Expired - Lifetime
- 1997-02-20 ES ES97905539T patent/ES2214608T3/es not_active Expired - Lifetime
- 1997-02-20 CA CA002247103A patent/CA2247103C/en not_active Expired - Fee Related
- 1997-02-20 DK DK97905539T patent/DK0944397T3/da active
- 1997-02-20 EP EP97905539A patent/EP0944397B1/en not_active Expired - Lifetime
- 1997-02-20 WO PCT/SE1997/000287 patent/WO1997030726A1/en active IP Right Grant
- 1997-02-20 NZ NZ331418A patent/NZ331418A/xx not_active IP Right Cessation
- 1997-02-20 BR BR9707638-4A patent/BR9707638A/pt not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
WO1997030726A1 (en) | 1997-08-28 |
EP0944397A1 (en) | 1999-09-29 |
NZ331418A (en) | 2000-03-27 |
ES2214608T3 (es) | 2004-09-16 |
CA2247103A1 (en) | 1997-08-28 |
DE69727314D1 (de) | 2004-02-26 |
EP0944397B1 (en) | 2004-01-21 |
AU718443B2 (en) | 2000-04-13 |
SE9600648D0 (sv) | 1996-02-21 |
AU2238397A (en) | 1997-09-10 |
US6027732A (en) | 2000-02-22 |
DK0944397T3 (da) | 2004-06-01 |
DE69727314T2 (de) | 2004-11-18 |
CA2247103C (en) | 2009-01-20 |
ATE258066T1 (de) | 2004-02-15 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FF | Decision: intention to grant | ||
HJEG | Technical examination (opinion): technical examination (opinion) related to article 229 of industrial property law | ||
HIFF | Patent grant cancelled | ||
FF | Decision: intention to grant | ||
HHFI | Decision: rectification | ||
HHFI | Decision: rectification | ||
FG9A | Patent or certificate of addition granted | ||
B24H | Lapse because of non-payment of annual fees (definitively: art 78 iv lpi) | ||
B24F | Patent annual fee: publication cancelled |
Free format text: ANULADA A PUBLICACAO CODIGO 24.8 NA RPI NO 2258 DE 15/04/2014 POR TER SIDO INDEVIDA. |
|
B21F | Lapse acc. art. 78, item iv - on non-payment of the annual fees in time |
Free format text: REFERENTE AS 15A, 16A, 17A, 18A, 19A E 20A ANUIDADES. |
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B24J | Lapse because of non-payment of annual fees (definitively: art 78 iv lpi, resolution 113/2013 art. 12) |
Free format text: EM VIRTUDE DA EXTINCAO PUBLICADA NA RPI 2607 DE 22-12-2020 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDA A EXTINCAO DA PATENTE E SEUS CERTIFICADOS, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013. |