SE0003538D0 - New immunogenic complex - Google Patents

New immunogenic complex

Info

Publication number
SE0003538D0
SE0003538D0 SE0003538A SE0003538A SE0003538D0 SE 0003538 D0 SE0003538 D0 SE 0003538D0 SE 0003538 A SE0003538 A SE 0003538A SE 0003538 A SE0003538 A SE 0003538A SE 0003538 D0 SE0003538 D0 SE 0003538D0
Authority
SE
Sweden
Prior art keywords
complex
iscom
antigen
immunogenic complex
integrated
Prior art date
Application number
SE0003538A
Other languages
English (en)
Inventor
Nils Lycke
Kristian Dalsgaard
Allan Mcmowat
Bjoern Loewenadler
Peter Kaastrup
Original Assignee
Isconova Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Isconova Ab filed Critical Isconova Ab
Priority to SE0003538A priority Critical patent/SE0003538D0/sv
Publication of SE0003538D0 publication Critical patent/SE0003538D0/sv
Priority to AT01972855T priority patent/ATE419870T1/de
Priority to CA2423983A priority patent/CA2423983C/en
Priority to US10/381,882 priority patent/US7452982B2/en
Priority to DE60137347T priority patent/DE60137347D1/de
Priority to PCT/SE2001/002117 priority patent/WO2002026255A1/en
Priority to EP01972855A priority patent/EP1320381B1/en
Priority to AU2001292493A priority patent/AU2001292493B2/en
Priority to AU9249301A priority patent/AU9249301A/xx

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/12Viral antigens
    • A61K39/145Orthomyxoviridae, e.g. influenza virus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/12Viral antigens
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/39Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/04Immunostimulants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/54Medicinal preparations containing antigens or antibodies characterised by the route of administration
    • A61K2039/541Mucosal route
    • A61K2039/542Mucosal route oral/gastrointestinal
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/54Medicinal preparations containing antigens or antibodies characterised by the route of administration
    • A61K2039/541Mucosal route
    • A61K2039/543Mucosal route intranasal
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/555Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511Organic adjuvants
    • A61K2039/55544Bacterial toxins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/555Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511Organic adjuvants
    • A61K2039/55577Saponins; Quil A; QS21; ISCOMS
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/57Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2760/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
    • C12N2760/00011Details
    • C12N2760/16011Orthomyxoviridae
    • C12N2760/16111Influenzavirus A, i.e. influenza A virus
    • C12N2760/16134Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
SE0003538A 2000-09-29 2000-09-29 New immunogenic complex SE0003538D0 (sv)

Priority Applications (9)

Application Number Priority Date Filing Date Title
SE0003538A SE0003538D0 (sv) 2000-09-29 2000-09-29 New immunogenic complex
AT01972855T ATE419870T1 (de) 2000-09-29 2001-10-01 Neuer immunogener komplex
CA2423983A CA2423983C (en) 2000-09-29 2001-10-01 An immunogenic iscom complex comprising an enzymatically active a1 subunit of the cholera toxin or e. coli heat labile enterotoxin fused to a dimer of the d region of protein a
US10/381,882 US7452982B2 (en) 2000-09-29 2001-10-01 Immunogenic complex
DE60137347T DE60137347D1 (de) 2000-09-29 2001-10-01 Neuer immunogener komplex
PCT/SE2001/002117 WO2002026255A1 (en) 2000-09-29 2001-10-01 New immunogenic complex
EP01972855A EP1320381B1 (en) 2000-09-29 2001-10-01 New immunogenic complex
AU2001292493A AU2001292493B2 (en) 2000-09-29 2001-10-01 New immunogenic complex
AU9249301A AU9249301A (en) 2000-09-29 2001-10-01 New immunogenic complex

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE0003538A SE0003538D0 (sv) 2000-09-29 2000-09-29 New immunogenic complex

Publications (1)

Publication Number Publication Date
SE0003538D0 true SE0003538D0 (sv) 2000-09-29

Family

ID=20281259

Family Applications (1)

Application Number Title Priority Date Filing Date
SE0003538A SE0003538D0 (sv) 2000-09-29 2000-09-29 New immunogenic complex

Country Status (8)

Country Link
US (1) US7452982B2 (sv)
EP (1) EP1320381B1 (sv)
AT (1) ATE419870T1 (sv)
AU (2) AU2001292493B2 (sv)
CA (1) CA2423983C (sv)
DE (1) DE60137347D1 (sv)
SE (1) SE0003538D0 (sv)
WO (1) WO2002026255A1 (sv)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6239116B1 (en) * 1994-07-15 2001-05-29 University Of Iowa Research Foundation Immunostimulatory nucleic acid molecules
US6207646B1 (en) * 1994-07-15 2001-03-27 University Of Iowa Research Foundation Immunostimulatory nucleic acid molecules
AU2008339093B2 (en) * 2007-12-19 2013-01-24 Toleranzia Ab Compositions and methods for treatment of autoimmune and allergic diseases
AU2011289579B2 (en) 2010-08-10 2016-11-17 Ecole Polytechnique Federale De Lausanne Erythrocyte-binding therapeutics
US9850296B2 (en) 2010-08-10 2017-12-26 Ecole Polytechnique Federale De Lausanne (Epfl) Erythrocyte-binding therapeutics
US9517257B2 (en) 2010-08-10 2016-12-13 Ecole Polytechnique Federale De Lausanne (Epfl) Erythrocyte-binding therapeutics
CA2900008A1 (en) 2013-02-07 2014-08-14 Children's Medical Center Corporation Protein antigens that provide protection against pneumococcal colonization and/or disease
KR20160135214A (ko) 2014-02-21 2016-11-25 에꼴 뽈리떼끄닉 뻬데랄 드 로잔느 (으뻬에프엘) 글리코타겟팅 치료제
US10046056B2 (en) 2014-02-21 2018-08-14 École Polytechnique Fédérale De Lausanne (Epfl) Glycotargeting therapeutics
US10953101B2 (en) 2014-02-21 2021-03-23 École Polytechnique Fédérale De Lausanne (Epfl) Glycotargeting therapeutics
US10946079B2 (en) 2014-02-21 2021-03-16 Ecole Polytechnique Federale De Lausanne Glycotargeting therapeutics
BR112017002440A2 (pt) 2014-08-08 2017-12-05 Univ Utrecht Holding Bv vírus da diarreia epizoótica porcina mutante para utilização em uma vacina
US20180161433A1 (en) * 2017-03-22 2018-06-14 Timothy Andrew Erickson Size tunable microbial mimetics for immunotherapy of thyroid carcinomas and solid tumors
EP3638296A1 (en) 2017-06-16 2020-04-22 The University Of Chicago Compositions and methods for inducing immune tolerance
CN110904127A (zh) 2018-09-18 2020-03-24 瓦赫宁恩研究基金会 非洲猪瘟病毒疫苗
US20230338519A1 (en) 2020-05-15 2023-10-26 Transmed Gothenburg Ab Fusion protein with immunoenhancing activity
WO2022019769A1 (en) 2020-07-23 2022-01-27 Universiteit Utrecht Holding B.V. Bordetella outer membrane vesicles

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5736139A (en) 1989-10-31 1998-04-07 Ochidian Pharmaceuticals, Inc. Treatment of Clostridium difficile induced disease
ATE196654T1 (de) 1992-06-26 2000-10-15 Univ Kansas State Fusobacterium necrophorum leukotoxoid vakzin
US5688772A (en) 1994-08-01 1997-11-18 University Of Saskatchewan Quinoa saponin compositions and methods of use
US5917026A (en) * 1996-02-05 1999-06-29 Loewenadler; Bjoern Fusion proteins of immunopotentiating activity
SE9600648D0 (sv) * 1996-02-21 1996-02-21 Bror Morein Receptorbimdande enhet

Also Published As

Publication number Publication date
CA2423983C (en) 2012-06-05
AU9249301A (en) 2002-04-08
US20040052815A1 (en) 2004-03-18
WO2002026255A1 (en) 2002-04-04
DE60137347D1 (de) 2009-02-26
US7452982B2 (en) 2008-11-18
AU2001292493B2 (en) 2006-10-26
CA2423983A1 (en) 2002-04-04
EP1320381B1 (en) 2009-01-07
EP1320381A1 (en) 2003-06-25
ATE419870T1 (de) 2009-01-15

Similar Documents

Publication Publication Date Title
SE0003538D0 (sv) New immunogenic complex
TR200002930T2 (tr) Kolaylaştırıcı kompozisyonlar
TR200102739T2 (tr) Aşı
IS4518A (is) Nýtt lyfjaform fyrir bóluefni
CR8231A (es) Anticuerpos rg1 y uso de los mismos
AU3438900A (en) Use of trehalose for stabilising a liquid vaccine
AU2001262345A1 (en) Antigenic composition comprising a polycationic peptide and inosine and cytosine
BRPI0511026C1 (pt) uso de um los neisserial, e, composição
MY137202A (en) System and method for a unified composition engine in a graphics processing system
WO2006073748A3 (en) Antibodies against antigen presenting cells and uses thereof
DK1379671T3 (da) Fremgangsmåder til dyrkning af circovirus
HK1033582A1 (en) Antibodies to death receptor 4 (dr4) and uses thereof
BR9806764A (pt) Moléculas mutantes ctla4 solúveis e usos das mesmas.
ATE389397T1 (de) Adjuvante zusammensetzungen
BR0109846A (pt) Uso de uma composição que compreende um anticorpo ou um fragmento de ligação de antìgeno deste, e conjunto
DE60003943D1 (de) Trimegestone enthaltende pharmazeutische zusammensetzungen
AU6078399A (en) Ligand presenting assembly (lpa), method of preparation and uses thereof
EP1594533A4 (en) ANTIBODY VACCINE CONJUGATES AND ITS USES
WO2000044775A3 (en) Identification of broadly reactive hla restricted t cell epitopes
BR0212289A (pt) Anticorpos contra caspase-8, preparação e uso do mesmo
EP1152606A3 (en) OSD system
AU2001294565A1 (en) In vitro assay for measuring the immunogenicity of a vaccine
Lezon et al. Asymmetric scoring functions for proteins
WO2003089453A3 (en) INHIBITION OF Ii EXPRESSION IN MAMMALIAN CELLS
Caillet et al. The White Angel-an enigmatic wollastonite-bearing F inclusion from the Leoville CV3 chondrite