BR9706229A - Uso de antagonistas receptores de dopamina na terapia paliativa de tumores - Google Patents
Uso de antagonistas receptores de dopamina na terapia paliativa de tumoresInfo
- Publication number
- BR9706229A BR9706229A BR9706229A BR9706229A BR9706229A BR 9706229 A BR9706229 A BR 9706229A BR 9706229 A BR9706229 A BR 9706229A BR 9706229 A BR9706229 A BR 9706229A BR 9706229 A BR9706229 A BR 9706229A
- Authority
- BR
- Brazil
- Prior art keywords
- receptor antagonists
- dopamine receptor
- tumor therapy
- palliative
- palliative tumor
- Prior art date
Links
- 229940121891 Dopamine receptor antagonist Drugs 0.000 title 1
- 206010028980 Neoplasm Diseases 0.000 title 1
- 239000003210 dopamine receptor blocking agent Substances 0.000 title 1
- 238000002560 therapeutic procedure Methods 0.000 title 1
- 230000000694 effects Effects 0.000 abstract 3
- 229940121683 Acetylcholine receptor antagonist Drugs 0.000 abstract 1
- 241001465754 Metazoa Species 0.000 abstract 1
- 239000005557 antagonist Substances 0.000 abstract 1
- 230000000259 anti-tumor effect Effects 0.000 abstract 1
- 230000037396 body weight Effects 0.000 abstract 1
- FGXWKSZFVQUSTL-UHFFFAOYSA-N domperidone Chemical compound C12=CC=CC=C2NC(=O)N1CCCN(CC1)CCC1N1C2=CC=C(Cl)C=C2NC1=O FGXWKSZFVQUSTL-UHFFFAOYSA-N 0.000 abstract 1
- 229960001253 domperidone Drugs 0.000 abstract 1
- PQLXHQMOHUQAKB-UHFFFAOYSA-N miltefosine Chemical compound CCCCCCCCCCCCCCCCOP([O-])(=O)OCC[N+](C)(C)C PQLXHQMOHUQAKB-UHFFFAOYSA-N 0.000 abstract 1
- 229960003775 miltefosine Drugs 0.000 abstract 1
- YVUQSNJEYSNKRX-UHFFFAOYSA-N pimozide Chemical compound C1=CC(F)=CC=C1C(C=1C=CC(F)=CC=1)CCCN1CCC(N2C(NC3=CC=CC=C32)=O)CC1 YVUQSNJEYSNKRX-UHFFFAOYSA-N 0.000 abstract 1
- 229960003634 pimozide Drugs 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
- A61K31/683—Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols
- A61K31/685—Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols one of the hydroxy compounds having nitrogen atoms, e.g. phosphatidylserine, lecithin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
- A61K31/454—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. pimozide, domperidone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Toxicology (AREA)
- Nutrition Science (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19650778A DE19650778C2 (de) | 1996-12-06 | 1996-12-06 | Verwendung von Dopaminrezeptor-Antagonisten in der palliativen Tumortherapie |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR9706229A true BR9706229A (pt) | 1999-05-04 |
Family
ID=7813911
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR9706229A BR9706229A (pt) | 1996-12-06 | 1997-12-04 | Uso de antagonistas receptores de dopamina na terapia paliativa de tumores |
Country Status (11)
| Country | Link |
|---|---|
| US (3) | US6093704A (pt) |
| EP (1) | EP0858807B1 (pt) |
| JP (1) | JPH10167969A (pt) |
| AT (1) | ATE192044T1 (pt) |
| BR (1) | BR9706229A (pt) |
| CA (1) | CA2223469C (pt) |
| DE (2) | DE19650778C2 (pt) |
| DK (1) | DK0858807T3 (pt) |
| ES (1) | ES2146063T3 (pt) |
| GR (1) | GR3033768T3 (pt) |
| PT (1) | PT858807E (pt) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ATE516036T1 (de) * | 2002-07-30 | 2011-07-15 | Fterna Zentaris Gmbh | Anwendung von alkylphosphocholinen in kombination mit antitumormedikamenten |
| US8383605B2 (en) * | 2002-07-30 | 2013-02-26 | Aeterna Zentaris Gmbh | Use of alkylphosphocholines in combination with antimetabolites for the treatment of benign and malignant oncoses in humans and mammals |
| JP5232009B2 (ja) | 2005-12-19 | 2013-07-10 | エテルナ ツェンタリス ゲゼルシャフト ミット ベシュレンクテル ハフツング | 低減された細胞毒性を有するアルキルリン脂質誘導体並びにそれらの使用 |
| US8835506B2 (en) * | 2008-06-05 | 2014-09-16 | Stc.Unm | Methods and related compositions for the treatment of cancer |
| CA2794513A1 (en) | 2010-03-31 | 2011-10-06 | Aeterna Zentaris Gmbh | Perifosine and capecitabine as a combined treatment for cancer |
| KR102500766B1 (ko) | 2017-12-29 | 2023-02-17 | 삼성전자주식회사 | 생체 신호 측정 장치 및 그의 동작 방법 |
| KR102203334B1 (ko) * | 2019-04-12 | 2021-01-15 | 성균관대학교산학협력단 | 피모자이드의 항암제 병용요법 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4707484A (en) * | 1986-11-25 | 1987-11-17 | Hoffmann-La Roche Inc. | Substituted piperidinomethylindolone and cyclopent(b)indolone derivatives |
| JPS6483016A (en) * | 1987-09-25 | 1989-03-28 | Arakawa Chem Ind | Regulator for motile function of gastrointestinal tract |
| RU2156248C2 (ru) * | 1995-07-28 | 2000-09-20 | Дайниппон Фармасьютикал Ко., Лтд. | (r)-5-бром-n-(1-этил-4-метилгексагидро-1h-1,4-диазепин-6-ил)-2-метокси-6-м етиламино-3-пиридинкарбоксамид, способ его получения, фармацевтическая композиция и противорвотное средство, содержащее указанное соединение, и его промежуточное соединение |
-
1996
- 1996-12-06 DE DE19650778A patent/DE19650778C2/de not_active Expired - Fee Related
-
1997
- 1997-11-29 ES ES97121009T patent/ES2146063T3/es not_active Expired - Lifetime
- 1997-11-29 EP EP97121009A patent/EP0858807B1/de not_active Expired - Lifetime
- 1997-11-29 DE DE59701508T patent/DE59701508D1/de not_active Expired - Fee Related
- 1997-11-29 DK DK97121009T patent/DK0858807T3/da active
- 1997-11-29 PT PT97121009T patent/PT858807E/pt unknown
- 1997-11-29 AT AT97121009T patent/ATE192044T1/de not_active IP Right Cessation
- 1997-12-03 JP JP9332646A patent/JPH10167969A/ja active Pending
- 1997-12-04 BR BR9706229A patent/BR9706229A/pt not_active Application Discontinuation
- 1997-12-04 CA CA002223469A patent/CA2223469C/en not_active Expired - Fee Related
- 1997-12-05 US US08/986,235 patent/US6093704A/en not_active Expired - Lifetime
-
2000
- 2000-06-23 GR GR20000401464T patent/GR3033768T3/el not_active IP Right Cessation
- 2000-06-23 US US09/599,561 patent/US6576624B1/en not_active Expired - Fee Related
-
2002
- 2002-08-02 US US10/210,881 patent/US6696428B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| DE19650778C2 (de) | 2001-01-04 |
| US6696428B2 (en) | 2004-02-24 |
| EP0858807A3 (de) | 1999-03-24 |
| EP0858807A2 (de) | 1998-08-19 |
| DE19650778A1 (de) | 1998-06-10 |
| DK0858807T3 (da) | 2000-07-31 |
| US6576624B1 (en) | 2003-06-10 |
| ES2146063T3 (es) | 2000-07-16 |
| GR3033768T3 (en) | 2000-10-31 |
| CA2223469A1 (en) | 1998-06-06 |
| DE59701508D1 (de) | 2000-05-31 |
| EP0858807B1 (de) | 2000-04-26 |
| PT858807E (pt) | 2000-09-29 |
| US6093704A (en) | 2000-07-25 |
| JPH10167969A (ja) | 1998-06-23 |
| ATE192044T1 (de) | 2000-05-15 |
| CA2223469C (en) | 2005-08-23 |
| US20030008846A1 (en) | 2003-01-09 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B25A | Requested transfer of rights approved |
Free format text: ZENTARIS AG (DE) |
|
| B25A | Requested transfer of rights approved |
Owner name: BLITZ F02-570 GMBH (DE) Free format text: TRANSFERIDO POR FUSAO DE: ZENTARIS AG |
|
| B25D | Requested change of name of applicant approved |
Owner name: ZENTARIS GMBH (DE) Free format text: ALTERADO DE: BLITZ F02-570 GMBH |
|
| B07A | Application suspended after technical examination (opinion) [chapter 7.1 patent gazette] | ||
| B09B | Patent application refused [chapter 9.2 patent gazette] |
Free format text: INDEFERIMENTO DO PRESENTE PEDIDO COM BASE NO ARTIGOS 8O COMBINADO COM O ARTIGO 13 DA LPI ( REIVINDICACOES 1-3 DO QUATRO ANTERIOR) E NO INICIO VIII DO ARTIGO 10 DA LPI ( REIVINDICACOES 4-9 DO QUADRO ANTERIOR ) |
|
| B12B | Appeal against refusal [chapter 12.2 patent gazette] |