ES2146063T3 - Empleo de antagonistas de receptores de dopamina en la terapia paliativa de tumores. - Google Patents

Empleo de antagonistas de receptores de dopamina en la terapia paliativa de tumores.

Info

Publication number
ES2146063T3
ES2146063T3 ES97121009T ES97121009T ES2146063T3 ES 2146063 T3 ES2146063 T3 ES 2146063T3 ES 97121009 T ES97121009 T ES 97121009T ES 97121009 T ES97121009 T ES 97121009T ES 2146063 T3 ES2146063 T3 ES 2146063T3
Authority
ES
Spain
Prior art keywords
employment
receptor antagonists
dopamine receptor
tumor therapy
palliative
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES97121009T
Other languages
English (en)
Inventor
Bernd Nickel
Thomas Klenner
Peter Hilgard
Juergen Engel
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Asta Medica GmbH
Original Assignee
Asta Medica GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Asta Medica GmbH filed Critical Asta Medica GmbH
Application granted granted Critical
Publication of ES2146063T3 publication Critical patent/ES2146063T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A61K31/683—Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols
    • A61K31/685—Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols one of the hydroxy compounds having nitrogen atoms, e.g. phosphatidylserine, lecithin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A61K31/454—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. pimozide, domperidone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00—General protective or antinoxious agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Toxicology (AREA)
  • Nutrition Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Peptides Or Proteins (AREA)

Abstract

LA PERDIDA DE PESO ASOCIADA AL TRATAMIENTO CON ALQUILFOSFOCOLINAS COMO EL MILTEFOSIN PUEDE ANTAGONIZARSE MEDIANTE DETERMINADOS ANTAGONISTAS COMO DOMPERIDON Y PIMOZID. LO IMPORTANTE ES QUE LA COMBINACION DE ALQUILFOSFOCOLINA Y ANTIDOTO NO INFLUYA EN LA ACCION ANTITUMORICA DE LA ALQUILFOSFOCOLINA. LA COMBINACION DEMOSTRO NO TENER TAMPOCO NUEVOS EFECTOS SECUNDARIOS SOBRE ANIMALES.
ES97121009T 1996-12-06 1997-11-29 Empleo de antagonistas de receptores de dopamina en la terapia paliativa de tumores. Expired - Lifetime ES2146063T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19650778A DE19650778C2 (de) 1996-12-06 1996-12-06 Verwendung von Dopaminrezeptor-Antagonisten in der palliativen Tumortherapie

Publications (1)

Publication Number Publication Date
ES2146063T3 true ES2146063T3 (es) 2000-07-16

Family

ID=7813911

Family Applications (1)

Application Number Title Priority Date Filing Date
ES97121009T Expired - Lifetime ES2146063T3 (es) 1996-12-06 1997-11-29 Empleo de antagonistas de receptores de dopamina en la terapia paliativa de tumores.

Country Status (11)

Country Link
US (3) US6093704A (es)
EP (1) EP0858807B1 (es)
JP (1) JPH10167969A (es)
AT (1) ATE192044T1 (es)
BR (1) BR9706229A (es)
CA (1) CA2223469C (es)
DE (2) DE19650778C2 (es)
DK (1) DK0858807T3 (es)
ES (1) ES2146063T3 (es)
GR (1) GR3033768T3 (es)
PT (1) PT858807E (es)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PT1545553E (pt) * 2002-07-30 2011-09-12 Aeterna Zentaris Gmbh Utilização de alquilfosfocolinas em combinação com medicamentos antitumorais
US8383605B2 (en) * 2002-07-30 2013-02-26 Aeterna Zentaris Gmbh Use of alkylphosphocholines in combination with antimetabolites for the treatment of benign and malignant oncoses in humans and mammals
JP5232009B2 (ja) 2005-12-19 2013-07-10 エテルナ ツェンタリス ゲゼルシャフト ミット ベシュレンクテル ハフツング 低減された細胞毒性を有するアルキルリン脂質誘導体並びにそれらの使用
WO2009148623A2 (en) 2008-06-05 2009-12-10 Stc.Unm Methods and related compositions for the treatment of cancer
WO2011123691A1 (en) 2010-03-31 2011-10-06 Keryx Biopharmaceuticals, Inc. Perifosine and capecitabine as a combined treatment for cancer
KR102500766B1 (ko) 2017-12-29 2023-02-17 삼성전자주식회사 생체 신호 측정 장치 및 그의 동작 방법
KR102203334B1 (ko) * 2019-04-12 2021-01-15 성균관대학교산학협력단 피모자이드의 항암제 병용요법

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4707484A (en) * 1986-11-25 1987-11-17 Hoffmann-La Roche Inc. Substituted piperidinomethylindolone and cyclopent(b)indolone derivatives
JPS6483016A (en) * 1987-09-25 1989-03-28 Arakawa Chem Ind Regulator for motile function of gastrointestinal tract
MX9800620A (es) * 1995-07-28 1998-04-30 Dainipon Pharmaceutical Co Ltd (r)-5-bromo-n-(1-etil-4-metilhexahidro-1h-1,4-diazepin-6-il- 2-metoxi-6-metilamino-3-piridincarboxamida, proceso para preparacion del mismo y composicion farmaceutica que contiene tal compuesto.

Also Published As

Publication number Publication date
CA2223469C (en) 2005-08-23
JPH10167969A (ja) 1998-06-23
US6696428B2 (en) 2004-02-24
US6093704A (en) 2000-07-25
EP0858807A3 (de) 1999-03-24
CA2223469A1 (en) 1998-06-06
DK0858807T3 (da) 2000-07-31
BR9706229A (pt) 1999-05-04
DE19650778C2 (de) 2001-01-04
EP0858807A2 (de) 1998-08-19
US6576624B1 (en) 2003-06-10
PT858807E (pt) 2000-09-29
US20030008846A1 (en) 2003-01-09
EP0858807B1 (de) 2000-04-26
DE19650778A1 (de) 1998-06-10
GR3033768T3 (en) 2000-10-31
ATE192044T1 (de) 2000-05-15
DE59701508D1 (de) 2000-05-31

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