BR9612755A - Peptìdeos inibidores de ice - Google Patents

Peptìdeos inibidores de ice

Info

Publication number
BR9612755A
BR9612755A BR9612755-4A BR9612755A BR9612755A BR 9612755 A BR9612755 A BR 9612755A BR 9612755 A BR9612755 A BR 9612755A BR 9612755 A BR9612755 A BR 9612755A
Authority
BR
Brazil
Prior art keywords
ice
terminus
enzymes
inhibition
peptide
Prior art date
Application number
BR9612755-4A
Other languages
English (en)
Inventor
Marta Muzio
Martino Introna
Alberto Mantovani
Original Assignee
Applied Research Systems
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Applied Research Systems filed Critical Applied Research Systems
Publication of BR9612755A publication Critical patent/BR9612755A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/54—Interleukins [IL]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/02—Non-specific cardiovascular stimulants, e.g. drugs for syncope, antihypotensives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Oncology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Communicable Diseases (AREA)
  • Biochemistry (AREA)
  • Zoology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Toxicology (AREA)
  • Virology (AREA)
  • Hematology (AREA)
  • Transplantation (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)

Abstract

Patente de Invenção:<B>"PEPTìDEOS INIBIDORES DE ICE"<D>. A presente invenção refere-se a um peptídeo capaz de ligação à ICE e/ou a enzimas da família ICE, cujo peptídeo consiste essencialmente na seq³ência de aminoácidos de SEQ ID NO:1 reportada na Listagem de Seq³ências, onde Xaa é selecionada entre Asp, e Ala, opcionalmente contendo um ou mais aminoácidos em sua extremidade terminal-N e/ou terminal-C. Ela também refere-se ao uso do peptídeo acima, para a preparação de composições farmacêuticas ativas em patologias requerendo inibição ICE e/ou inibição de enzimas da família ICE.
BR9612755-4A 1996-10-31 1996-10-31 Peptìdeos inibidores de ice BR9612755A (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/EP1996/004738 WO1998018823A1 (en) 1996-10-31 1996-10-31 Ice inhibiting peptides

Publications (1)

Publication Number Publication Date
BR9612755A true BR9612755A (pt) 1999-10-19

Family

ID=8166387

Family Applications (1)

Application Number Title Priority Date Filing Date
BR9612755-4A BR9612755A (pt) 1996-10-31 1996-10-31 Peptìdeos inibidores de ice

Country Status (20)

Country Link
US (1) US6380162B1 (pt)
EP (1) EP0938500B1 (pt)
JP (1) JP4018154B2 (pt)
KR (1) KR100502211B1 (pt)
AR (1) AR011269A1 (pt)
AT (1) ATE277079T1 (pt)
BR (1) BR9612755A (pt)
CA (1) CA2269638C (pt)
DE (1) DE69633463T2 (pt)
DK (1) DK0938500T3 (pt)
EA (1) EA001866B1 (pt)
EE (1) EE04782B1 (pt)
ES (1) ES2225893T3 (pt)
IL (1) IL129669A0 (pt)
NO (1) NO323517B1 (pt)
PT (1) PT938500E (pt)
SI (1) SI0938500T1 (pt)
UA (1) UA70291C2 (pt)
WO (1) WO1998018823A1 (pt)
ZA (1) ZA979712B (pt)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HUE029021T2 (en) * 2005-06-21 2017-02-28 Xoma (Us) Llc IL-1beta-binding antibodies and fragments thereof

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5981713A (en) * 1994-10-13 1999-11-09 Applied Research Systems Ars Holding N.V. Antibodies to intereleukin-1 antagonists
IT1270662B (it) 1994-10-13 1997-05-07 Applied Research Systems Antagonista della interleuchina-1

Also Published As

Publication number Publication date
ATE277079T1 (de) 2004-10-15
AR011269A1 (es) 2000-08-16
US6380162B1 (en) 2002-04-30
IL129669A0 (en) 2000-02-29
KR100502211B1 (ko) 2005-07-19
JP4018154B2 (ja) 2007-12-05
NO992079D0 (no) 1999-04-29
CA2269638C (en) 2005-01-18
PT938500E (pt) 2005-02-28
DE69633463D1 (de) 2004-10-28
ZA979712B (en) 1999-02-05
JP2001510452A (ja) 2001-07-31
AU2702399A (en) 1999-08-16
EE04782B1 (et) 2007-02-15
NO992079L (no) 1999-06-16
ES2225893T3 (es) 2005-03-16
WO1998018823A1 (en) 1998-05-07
DK0938500T3 (da) 2005-01-17
SI0938500T1 (en) 2005-02-28
WO1998018823A8 (en) 1999-06-17
AU729946B2 (en) 2001-02-15
CA2269638A1 (en) 1998-05-07
UA70291C2 (en) 2004-10-15
EP0938500B1 (en) 2004-09-22
EA001866B1 (ru) 2001-10-22
DE69633463T2 (de) 2006-02-23
EA199900432A1 (ru) 1999-10-28
NO323517B1 (no) 2007-06-04
EP0938500A1 (en) 1999-09-01
EE9900178A (et) 1999-12-15
KR20000052858A (ko) 2000-08-25

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BR9612755A (pt) Peptìdeos inibidores de ice
EP0979829A3 (de) Kosmetische oder dermatologische Zubereitungen mit einem Gehalt an Oligopeptiden zur Hautaufhellung von Altersflecken bzw. zur Verhinderung der Hautbräunung, insbesondere der durch UV-Strahlung hervorgerufenen Hautbräunung

Legal Events

Date Code Title Description
TE Change of address
B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B06A Patent application procedure suspended [chapter 6.1 patent gazette]
B09B Patent application refused [chapter 9.2 patent gazette]

Free format text: DE ACORDO COM O ARTIGO 37, INDEFIRO O PRESENTE PEDIDO, TENDO POR BASE O ARTIGO 8O COMBINADO COM O ARTIGO 13, ARTIGO 10 INCISO IX, ARTIGO 25 E ARTIGO 36 DA LPI 9279 DE 14/05/96.