BR9610207A - Acidos fenóxi acéticos como inibidores da aldose redutase e agentes anti-hiperglicêmicos - Google Patents
Acidos fenóxi acéticos como inibidores da aldose redutase e agentes anti-hiperglicêmicosInfo
- Publication number
- BR9610207A BR9610207A BR9610207A BR9610207A BR9610207A BR 9610207 A BR9610207 A BR 9610207A BR 9610207 A BR9610207 A BR 9610207A BR 9610207 A BR9610207 A BR 9610207A BR 9610207 A BR9610207 A BR 9610207A
- Authority
- BR
- Brazil
- Prior art keywords
- reductase inhibitors
- aldose reductase
- acetic acids
- phenoxy acetic
- hyperglycemic agents
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
- C07C69/66—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety
- C07C69/67—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety of saturated acids
- C07C69/708—Ethers
- C07C69/712—Ethers the hydroxy group of the ester being etherified with a hydroxy compound having the hydroxy group bound to a carbon atom of a six-membered aromatic ring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
- C07C45/67—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
- C07C45/68—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C47/00—Compounds having —CHO groups
- C07C47/52—Compounds having —CHO groups bound to carbon atoms of six—membered aromatic rings
- C07C47/575—Compounds having —CHO groups bound to carbon atoms of six—membered aromatic rings containing ether groups, groups, groups, or groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C59/40—Unsaturated compounds
- C07C59/74—Unsaturated compounds containing —CHO groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Diabetes (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Obesity (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Hematology (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Emergency Medicine (AREA)
- Endocrinology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US285595P | 1995-08-28 | 1995-08-28 | |
| PCT/US1996/012550 WO1997008126A1 (en) | 1995-08-28 | 1996-08-01 | Phenoxy acetic acids as aldose reductase inhibitors and antihyperglycemic agents |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR9610207A true BR9610207A (pt) | 1999-02-02 |
Family
ID=21702866
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR9610207A BR9610207A (pt) | 1995-08-28 | 1996-08-01 | Acidos fenóxi acéticos como inibidores da aldose redutase e agentes anti-hiperglicêmicos |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US5677342A (pt) |
| EP (1) | EP0847379A1 (pt) |
| JP (1) | JPH11512095A (pt) |
| CN (1) | CN1200106A (pt) |
| AU (1) | AU701068B2 (pt) |
| BR (1) | BR9610207A (pt) |
| CA (1) | CA2227691A1 (pt) |
| NZ (1) | NZ313896A (pt) |
| WO (1) | WO1997008126A1 (pt) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6121271A (en) * | 1998-05-12 | 2000-09-19 | American Home Products Corporation | Naphtho[2,3-B]heteroar-4-yl derivatives |
| JP2002514639A (ja) * | 1998-05-12 | 2002-05-21 | アメリカン・ホーム・プロダクツ・コーポレイション | ナフト［２，３−ｂ］ヘテロアリー−４−イル誘導体 |
| WO2002024633A1 (fr) * | 2000-09-21 | 2002-03-28 | Sankyo Company, Limited | Derives d'acide phenylpropionique |
| SE0301010D0 (sv) | 2003-04-07 | 2003-04-07 | Astrazeneca Ab | Novel compounds |
| SA04250253B1 (ar) | 2003-08-21 | 2009-11-10 | استرازينيكا ايه بي | احماض فينوكسي اسيتيك مستبدلة باعتبارها مركبات صيدلانية لعلاج الامراض التنفسية مثل الربو ومرض الانسداد الرئوي المزمن |
| GB0415320D0 (en) | 2004-07-08 | 2004-08-11 | Astrazeneca Ab | Novel compounds |
| GB0418830D0 (en) | 2004-08-24 | 2004-09-22 | Astrazeneca Ab | Novel compounds |
| DK1817282T3 (da) | 2004-11-23 | 2011-10-10 | Astrazeneca Ab | Til behandling af respiratoriske sygdomme egnede phenoxy derivater |
| TW200745003A (en) | 2005-10-06 | 2007-12-16 | Astrazeneca Ab | Novel compounds |
| JP5155171B2 (ja) | 2005-10-06 | 2013-02-27 | アストラゼネカ・アクチエボラーグ | 新規化合物 |
| UA100983C2 (ru) | 2007-07-05 | 2013-02-25 | Астразенека Аб | Бифенилоксипропановая кислота как модулятор crth2 и интермедиаты |
| JP5934206B2 (ja) | 2010-07-16 | 2016-06-15 | ザ・トラスティーズ・オブ・コロンビア・ユニバーシティ・イン・ザ・シティ・オブ・ニューヨーク | アルドース還元酵素阻害剤および同使用方法 |
| US8916563B2 (en) | 2010-07-16 | 2014-12-23 | The Trustees Of Columbia University In The City Of New York | Aldose reductase inhibitors and uses thereof |
| IL304979A (en) | 2016-06-21 | 2023-10-01 | Univ Columbia | Aldose reductase inhibitors and methods of using them |
| PT3658142T (pt) | 2017-07-28 | 2024-06-27 | Applied Therapeutics Inc | Composições e métodos para tratar galactosemia |
| AU2020254610A1 (en) | 2019-04-01 | 2021-11-18 | Applied Therapeutics Inc. | Inhibitors of aldose reductase |
| AU2021264454A1 (en) | 2020-05-01 | 2022-12-08 | Applied Therapeutics, Inc. | Aldose reductase inhibitors for treating sorbitol dehydrogenase deficiency |
| CN112574136A (zh) * | 2020-12-08 | 2021-03-30 | 北京理工大学 | 一系列苯并噁唑酮类衍生物的结构、制备方法及用途 |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| HU190371B (en) * | 1980-12-18 | 1986-08-28 | The Wellcome Foundation Ltd,Gb | Process for producing ether-type compounds and pharmaceutical compositions containing them as active agents |
| US4500544A (en) * | 1981-09-10 | 1985-02-19 | Chugai Seiyaku Kabushiki Kaisha | Ascochlorin derivatives, and pharmaceutical composition containing the same |
| JP2558473B2 (ja) * | 1987-08-24 | 1996-11-27 | 大日本製薬株式会社 | チアゾリジン誘導体 |
| US4897405A (en) * | 1989-04-21 | 1990-01-30 | American Home Products Corporation | Novel naphthalenylalkyl-3H-1,2,3,5-oxathiadiazole 2-oxides useful as antihyperglycemic agents |
| JP2873599B2 (ja) * | 1990-03-09 | 1999-03-24 | 寿製薬株式会社 | 新規ベンゾフラン誘導体、尿酸排泄剤及びその製法 |
| US5183825A (en) * | 1992-04-07 | 1993-02-02 | American Home Products Corporation | 4-arylmethyl-5-alkyl-3H-pyrazol-3-ones and hypoglycemic use |
| US5324743A (en) * | 1992-12-10 | 1994-06-28 | Eli Lilly And Company | Leukotriene B4 antagonists |
| US5399588A (en) * | 1993-12-14 | 1995-03-21 | American Home Products Corporation | Naphthalenylmethyl cycloalkenone acetic acids and analogs thereof useful as aldose reductase inhibitors |
-
1996
- 1996-08-01 BR BR9610207A patent/BR9610207A/pt not_active Application Discontinuation
- 1996-08-01 JP JP9510270A patent/JPH11512095A/ja active Pending
- 1996-08-01 NZ NZ313896A patent/NZ313896A/xx unknown
- 1996-08-01 CA CA002227691A patent/CA2227691A1/en not_active Abandoned
- 1996-08-01 AU AU66438/96A patent/AU701068B2/en not_active Ceased
- 1996-08-01 EP EP96926208A patent/EP0847379A1/en not_active Ceased
- 1996-08-01 WO PCT/US1996/012550 patent/WO1997008126A1/en not_active Application Discontinuation
- 1996-08-01 CN CN96197719A patent/CN1200106A/zh active Pending
- 1996-08-21 US US08/701,144 patent/US5677342A/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| AU6643896A (en) | 1997-03-19 |
| CN1200106A (zh) | 1998-11-25 |
| EP0847379A1 (en) | 1998-06-17 |
| AU701068B2 (en) | 1999-01-21 |
| JPH11512095A (ja) | 1999-10-19 |
| WO1997008126A1 (en) | 1997-03-06 |
| US5677342A (en) | 1997-10-14 |
| NZ313896A (en) | 2000-08-25 |
| CA2227691A1 (en) | 1997-03-06 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FA10 | Dismissal: dismissal - article 33 of industrial property law |