BR9509671C1 - Derivados de dibenzimidazol - Google Patents
Derivados de dibenzimidazolInfo
- Publication number
- BR9509671C1 BR9509671C1 BR9509671-0A BR9509671A BR9509671C1 BR 9509671 C1 BR9509671 C1 BR 9509671C1 BR 9509671 A BR9509671 A BR 9509671A BR 9509671 C1 BR9509671 C1 BR 9509671C1
- Authority
- BR
- Brazil
- Prior art keywords
- derivatives
- alkoxy
- formula
- dibenzimidazole derivatives
- dibenzimidazoles
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
- C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
- C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
- C07D235/20—Two benzimidazolyl-2 radicals linked together directly or via a hydrocarbon or substituted hydrocarbon radical
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/415—1,2-Diazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Oncology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Communicable Diseases (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Patente de Invenção: "DERIVADOS DE DIBENZIMIDAZOL". Dibenzimidazóis novos e conhecidos da fórmula: onde: R^ 1^ e R^ 2^ podem ser os mesmos ou diferentes e significam C~ 6~H~ 4~ R^ 3^-, C~ 6~H~ 3~(OH)R^ 4^ - ou heterociclila, R^ 3^ significa hidróxi, amino, alcóxi inferior ou ciano e R^ 4^ significa halogênio, alquila inferior ou alcóxi inferior, bem como sais farmaceuticamente utilizáveis dos compostos da fórmula geral I são antibacterianos, especialmente contra Staphylococcus, Enterococcus e Heliobacter pylori.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CH345994 | 1994-11-17 | ||
PCT/CH1995/000255 WO1996016042A1 (de) | 1994-11-17 | 1995-11-02 | Antibakterielle dibenzimidazol-derivate |
Publications (2)
Publication Number | Publication Date |
---|---|
BR9509671A BR9509671A (pt) | 1997-10-28 |
BR9509671C1 true BR9509671C1 (pt) | 2000-04-18 |
Family
ID=4256402
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR9509671-0A BR9509671C1 (pt) | 1994-11-17 | 1995-11-02 | Derivados de dibenzimidazol |
Country Status (9)
Country | Link |
---|---|
US (1) | US5824698A (pt) |
EP (1) | EP0793654A1 (pt) |
JP (1) | JPH09512831A (pt) |
AU (1) | AU3696495A (pt) |
BR (1) | BR9509671C1 (pt) |
CA (1) | CA2204639A1 (pt) |
FI (1) | FI972090A (pt) |
MX (1) | MX9703634A (pt) |
WO (1) | WO1996016042A1 (pt) |
Families Citing this family (21)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB9908828D0 (en) | 1999-04-16 | 1999-06-16 | Univ Reading The | Compounds |
CA2371728C (en) * | 1999-06-11 | 2009-06-02 | Neorx Corporation | High dose radionuclide complexes for bone marrow suppression |
US7094885B2 (en) | 1999-07-11 | 2006-08-22 | Neorx Corporation | Skeletal-targeted radiation to treat bone-associated pathologies |
US6403652B1 (en) | 2000-06-30 | 2002-06-11 | Colgate-Palmolive Company | Method and composition |
JP2004536034A (ja) * | 2001-01-08 | 2004-12-02 | ネオルクス コーポレイション | 治療的および診断的化合物、組成物および方法 |
US7701130B2 (en) | 2001-08-24 | 2010-04-20 | Semiconductor Energy Laboratory Co., Ltd. | Luminous device with conductive film |
AU2002364552A1 (en) | 2001-12-13 | 2003-06-30 | Dow Global Technologies Inc. | Treatment of osteomyelitis with radiopharmaceuticals |
KR100629060B1 (ko) | 2004-08-11 | 2006-09-26 | 주식회사 엘지화학 | 새로운 벤즈이미다졸계 화합물 |
DE102005017508A1 (de) * | 2005-04-15 | 2006-10-19 | Basf Ag | Verfahren zur Gewinnung einer basischen Aminosäure aus einer Fermentationsbrühe II |
GB0821913D0 (en) * | 2008-12-02 | 2009-01-07 | Price & Co | Antibacterial compounds |
WO2011151617A1 (en) | 2010-06-01 | 2011-12-08 | Summit Corporation Plc | Compounds for the treatment of clostridium difficile associated disease |
WO2011151619A1 (en) | 2010-06-01 | 2011-12-08 | Summit Corporation Plc | Compounds for the treatment of clostridium difficile associated disease |
WO2011151618A2 (en) | 2010-06-01 | 2011-12-08 | Summit Corporation Plc | Compounds for the treatment of clostridium difficile-associated disease |
GB2480814A (en) * | 2010-06-01 | 2011-12-07 | Summit Corp Plc | Compounds for the treatment of clostridium difficile-associated disease |
WO2011151620A1 (en) * | 2010-06-01 | 2011-12-08 | Summit Corporation Plc | Compounds for the treatment of clostridium difficile associated disease |
DK2575968T3 (en) | 2010-06-01 | 2016-05-30 | Summit Therapeutics Plc | COMPOUNDS FOR THE TREATMENT OF Clostridium difficile-associated disease |
GB2480813A (en) * | 2010-06-01 | 2011-12-07 | Summit Corp Plc | Compounds for the treatment of clostridium difficile-associated disease |
US9079935B2 (en) | 2012-08-13 | 2015-07-14 | The Board Of Regents Of The Nevada System Of Higher Education On Behalf Of The University Of Nevada, Las Vegas | Reducing risk of contracting Clostridium-difficile associated disease |
WO2016127102A2 (en) | 2015-02-06 | 2016-08-11 | Ernesto Abel-Santos | Inhibiting germination of clostridium perfringens spores to reduce necrotic enteritis |
WO2021009514A1 (en) | 2019-07-17 | 2021-01-21 | Summit (Oxford) Limited | Process for the preparation of ridinilazole and crystalline forms thereof |
GB202100471D0 (en) | 2021-01-14 | 2021-03-03 | Summit Oxford Ltd | Preparation of antibacterial compounds |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4087409A (en) * | 1966-11-07 | 1978-05-02 | Monsanto Company | Ordered heterocyclic copolymers |
US3484407A (en) * | 1967-01-13 | 1969-12-16 | Monsanto Co | Linear condensation polymers containing carbonamide and heterocyclic linkages |
US3592821A (en) * | 1968-05-21 | 1971-07-13 | Ciba Ltd | 2-(2'-hydroxy-3',5'-dichlorophenyl)-5-chloro- or 5-methylbenzimidazoles |
US4665066A (en) * | 1984-12-24 | 1987-05-12 | Eli Lilly And Company | 3-thiazolomethyl cephalosporins as antibiotics |
US4960790A (en) * | 1989-03-09 | 1990-10-02 | University Of Kansas | Derivatives of taxol, pharmaceutical compositions thereof and methods for the preparation thereof |
US5412059A (en) * | 1993-04-05 | 1995-05-02 | The United States Of America As Represented By The Administrator Of The National Aeronautics And Space Administration | Polybenzimidazoles via aromatic nucleophilic displacement |
-
1995
- 1995-11-02 CA CA002204639A patent/CA2204639A1/en not_active Abandoned
- 1995-11-02 WO PCT/CH1995/000255 patent/WO1996016042A1/de not_active Application Discontinuation
- 1995-11-02 AU AU36964/95A patent/AU3696495A/en not_active Abandoned
- 1995-11-02 EP EP95934584A patent/EP0793654A1/de not_active Withdrawn
- 1995-11-02 JP JP8516410A patent/JPH09512831A/ja active Pending
- 1995-11-02 US US08/836,423 patent/US5824698A/en not_active Expired - Fee Related
- 1995-11-02 MX MX9703634A patent/MX9703634A/es not_active Application Discontinuation
- 1995-11-02 BR BR9509671-0A patent/BR9509671C1/pt unknown
-
1997
- 1997-05-15 FI FI972090A patent/FI972090A/fi unknown
Also Published As
Publication number | Publication date |
---|---|
FI972090A0 (fi) | 1997-05-15 |
MX9703634A (es) | 1997-08-30 |
BR9509671A (pt) | 1997-10-28 |
AU3696495A (en) | 1996-06-17 |
CA2204639A1 (en) | 1996-05-30 |
JPH09512831A (ja) | 1997-12-22 |
FI972090A (fi) | 1997-05-15 |
WO1996016042A1 (de) | 1996-05-30 |
US5824698A (en) | 1998-10-20 |
EP0793654A1 (de) | 1997-09-10 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] |