BR9307844A - Processo para a formaçao de uma célula livre de antigenes para transplante célula livre de antigenes para transplante oligonucleotideo capaz de ligaçao a uma sequéncia nucleotidea antigene para transplante oligonucleotideo para utilizaçao na preparaçao de uma composiçao para o tratamento de células alvo orgao doador universal e processo para o tratamento de um individuo com uma doença autoimune - Google Patents

Processo para a formaçao de uma célula livre de antigenes para transplante célula livre de antigenes para transplante oligonucleotideo capaz de ligaçao a uma sequéncia nucleotidea antigene para transplante oligonucleotideo para utilizaçao na preparaçao de uma composiçao para o tratamento de células alvo orgao doador universal e processo para o tratamento de um individuo com uma doença autoimune

Info

Publication number
BR9307844A
BR9307844A BR9307844A BR9307844A BR9307844A BR 9307844 A BR9307844 A BR 9307844A BR 9307844 A BR9307844 A BR 9307844A BR 9307844 A BR9307844 A BR 9307844A BR 9307844 A BR9307844 A BR 9307844A
Authority
BR
Brazil
Prior art keywords
transplantation
antigen
oligonucleotide
treatment
free cell
Prior art date
Application number
BR9307844A
Other languages
English (en)
Inventor
Tania L Weiss
Marvin R Garovoy
Anthony Hunt
Bing Huey
Schuman Tam
Original Assignee
Univ California
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ California filed Critical Univ California
Publication of BR9307844A publication Critical patent/BR9307844A/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
    • C12N15/1138—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing against receptors or cell surface proteins
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2310/00—Structure or type of the nucleic acid
    • C12N2310/10—Type of nucleic acid
    • C12N2310/15—Nucleic acids forming more than 2 strands, e.g. TFOs
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2310/00—Structure or type of the nucleic acid
    • C12N2310/30—Chemical structure
    • C12N2310/32—Chemical structure of the sugar
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2310/00—Structure or type of the nucleic acid
    • C12N2310/30—Chemical structure
    • C12N2310/32—Chemical structure of the sugar
    • C12N2310/321—2'-O-R Modification
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2310/00—Structure or type of the nucleic acid
    • C12N2310/30—Chemical structure
    • C12N2310/35—Nature of the modification
    • C12N2310/353—Nature of the modification linked to the nucleic acid via an atom other than carbon
    • C12N2310/3535—Nitrogen

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Zoology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Wood Science & Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biophysics (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Plant Pathology (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Saccharide Compounds (AREA)
BR9307844A 1992-01-31 1993-01-29 Processo para a formaçao de uma célula livre de antigenes para transplante célula livre de antigenes para transplante oligonucleotideo capaz de ligaçao a uma sequéncia nucleotidea antigene para transplante oligonucleotideo para utilizaçao na preparaçao de uma composiçao para o tratamento de células alvo orgao doador universal e processo para o tratamento de um individuo com uma doença autoimune BR9307844A (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US83042792A 1992-01-31 1992-01-31
US94486892A 1992-09-14 1992-09-14
PCT/US1993/000797 WO1993014769A1 (en) 1992-01-31 1993-01-29 Method for making universal donor cells

Publications (1)

Publication Number Publication Date
BR9307844A true BR9307844A (pt) 1996-01-09

Family

ID=27125355

Family Applications (1)

Application Number Title Priority Date Filing Date
BR9307844A BR9307844A (pt) 1992-01-31 1993-01-29 Processo para a formaçao de uma célula livre de antigenes para transplante célula livre de antigenes para transplante oligonucleotideo capaz de ligaçao a uma sequéncia nucleotidea antigene para transplante oligonucleotideo para utilizaçao na preparaçao de uma composiçao para o tratamento de células alvo orgao doador universal e processo para o tratamento de um individuo com uma doença autoimune

Country Status (9)

Country Link
EP (1) EP0626852A4 (pt)
JP (1) JPH07503612A (pt)
AU (1) AU3598293A (pt)
BR (1) BR9307844A (pt)
CA (1) CA2126692A1 (pt)
CZ (1) CZ178394A3 (pt)
HU (1) HUT67676A (pt)
NO (1) NO942680L (pt)
WO (1) WO1993014769A1 (pt)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2110946A1 (en) 1992-12-09 1994-06-10 Elazar Rabbani Induction of immunocompatibility by nucleic acid
CA2158933A1 (en) * 1993-09-03 1995-03-09 John F. Warner Methods of suppressing graft rejection
DE69426303T2 (de) * 1993-09-03 2001-05-31 Chiron Corp Verfahren zur unterdrückung der immunantwort durch gentherapie
JPH09503655A (ja) * 1993-09-03 1997-04-15 チロン ビアジーン インコーポレイティド 自己免疫応答の抑制方法
DE10019252A1 (de) * 2000-04-18 2001-10-31 Klaus Karl Degitz Polydesoxyribonukleotide zur Hemmung der ICAM-1-Genexpression

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2732544B2 (ja) * 1990-08-14 1998-03-30 アイシス・ファーマシューティカルス・インコーポレーテッド 細胞接着のオリゴヌクレオチド変調
DE69332668T2 (de) * 1992-09-02 2003-12-18 Isis Pharmaceutical Inc Beeinflussing der zelladhäsie durch oligonukleotide
CA2110946A1 (en) * 1992-12-09 1994-06-10 Elazar Rabbani Induction of immunocompatibility by nucleic acid

Also Published As

Publication number Publication date
WO1993014769A1 (en) 1993-08-05
EP0626852A1 (en) 1994-12-07
CZ178394A3 (en) 1995-03-15
HU9402188D0 (en) 1994-09-28
EP0626852A4 (en) 1996-03-20
CA2126692A1 (en) 1993-08-05
NO942680L (no) 1994-08-24
HUT67676A (en) 1995-04-28
AU3598293A (en) 1993-09-01
NO942680D0 (no) 1994-07-15
JPH07503612A (ja) 1995-04-20

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