EP0626852A4 - Method for making universal donor cells. - Google Patents

Method for making universal donor cells.

Info

Publication number
EP0626852A4
EP0626852A4 EP93904719A EP93904719A EP0626852A4 EP 0626852 A4 EP0626852 A4 EP 0626852A4 EP 93904719 A EP93904719 A EP 93904719A EP 93904719 A EP93904719 A EP 93904719A EP 0626852 A4 EP0626852 A4 EP 0626852A4
Authority
EP
European Patent Office
Prior art keywords
donor cells
universal donor
making universal
making
cells
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP93904719A
Other versions
EP0626852A1 (en
Inventor
Tania L Weiss
Marvin R Garovoy
Anthony Hunt
Bing Huey
Schuman Tam
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of California
Original Assignee
University of California
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by University of California filed Critical University of California
Publication of EP0626852A1 publication Critical patent/EP0626852A1/en
Publication of EP0626852A4 publication Critical patent/EP0626852A4/en
Withdrawn legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
    • C12N15/1138—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing against receptors or cell surface proteins
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2310/00—Structure or type of the nucleic acid
    • C12N2310/10—Type of nucleic acid
    • C12N2310/15—Nucleic acids forming more than 2 strands, e.g. TFOs
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2310/00—Structure or type of the nucleic acid
    • C12N2310/30—Chemical structure
    • C12N2310/32—Chemical structure of the sugar
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2310/00—Structure or type of the nucleic acid
    • C12N2310/30—Chemical structure
    • C12N2310/32—Chemical structure of the sugar
    • C12N2310/321—2'-O-R Modification
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2310/00—Structure or type of the nucleic acid
    • C12N2310/30—Chemical structure
    • C12N2310/35—Nature of the modification
    • C12N2310/353—Nature of the modification linked to the nucleic acid via an atom other than carbon
    • C12N2310/3535—Nitrogen

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • General Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biotechnology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Plant Pathology (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Biophysics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Saccharide Compounds (AREA)
EP93904719A 1992-01-31 1993-01-29 Method for making universal donor cells. Withdrawn EP0626852A4 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US83042792A 1992-01-31 1992-01-31
US830427 1992-01-31
US94486892A 1992-09-14 1992-09-14
US944868 1992-09-14
PCT/US1993/000797 WO1993014769A1 (en) 1992-01-31 1993-01-29 Method for making universal donor cells

Publications (2)

Publication Number Publication Date
EP0626852A1 EP0626852A1 (en) 1994-12-07
EP0626852A4 true EP0626852A4 (en) 1996-03-20

Family

ID=27125355

Family Applications (1)

Application Number Title Priority Date Filing Date
EP93904719A Withdrawn EP0626852A4 (en) 1992-01-31 1993-01-29 Method for making universal donor cells.

Country Status (9)

Country Link
EP (1) EP0626852A4 (en)
JP (1) JPH07503612A (en)
AU (1) AU3598293A (en)
BR (1) BR9307844A (en)
CA (1) CA2126692A1 (en)
CZ (1) CZ178394A3 (en)
HU (1) HUT67676A (en)
NO (1) NO942680L (en)
WO (1) WO1993014769A1 (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2110946A1 (en) 1992-12-09 1994-06-10 Elazar Rabbani Induction of immunocompatibility by nucleic acid
JPH09503655A (en) * 1993-09-03 1997-04-15 チロン ビアジーン インコーポレイティド Method of suppressing autoimmune response
CA2158933A1 (en) * 1993-09-03 1995-03-09 John F. Warner Methods of suppressing graft rejection
AU7830794A (en) * 1993-09-03 1995-03-22 Chiron Corporation Methods of suppressing immune response by gene therapy
DE10019252A1 (en) * 2000-04-18 2001-10-31 Klaus Karl Degitz Polydeoxyribonucleotides to inhibit ICAM-1 gene expression

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1992003139A1 (en) * 1990-08-14 1992-03-05 Isis Pharmaceuticals, Inc. Oligonucleotide modulation of cell adhesion
WO1994005333A1 (en) * 1992-09-02 1994-03-17 Isis Pharmaceuticals, Inc. Oligonucleotide modulation of cell adhesion
EP0601585A2 (en) * 1992-12-09 1994-06-15 Enzo Therapeutics, Inc. Nucleic acid construct for inhibiting or regulating the functions of an immuno response gene, method utilizing the same and immunologically compatible system containing the same

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1992003139A1 (en) * 1990-08-14 1992-03-05 Isis Pharmaceuticals, Inc. Oligonucleotide modulation of cell adhesion
WO1994005333A1 (en) * 1992-09-02 1994-03-17 Isis Pharmaceuticals, Inc. Oligonucleotide modulation of cell adhesion
EP0601585A2 (en) * 1992-12-09 1994-06-15 Enzo Therapeutics, Inc. Nucleic acid construct for inhibiting or regulating the functions of an immuno response gene, method utilizing the same and immunologically compatible system containing the same

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
CHIANG, M.-Y. ET AL.: "Antisense oligonucleotides inhibit intercellular adhesion molecule 1 expression by two distinct mechanisms", JOURNAL OF BIOLOGICAL CHEMISTRY, vol. 266, no. 27, 25 September 1991 (1991-09-25), MD US, pages 18162 - 18171, XP002134405 *
GIACOMINI, P. ET AL.: "BLOCK OF TRANSLATION OF HUMAN HLA-DR-ALPHA MESSENGER RNA BY AN ANTISENSE OLIGODEOXYNUCLEOTIDE.", SEVENTH MEETING OF THE ITALIAN ASSOCIATION FOR CELL BIOLOGY AND DIFFERENTIATION, SPOLETO, ITALY, OCTOBER 16-19, 1988. EUR J CELL BIOL SUPPL 47 (23). 1988. 13 *
MATSUNAGA, T. ET AL.: "SPECIFIC INHIBITION OF BETA-2 MICROGLOBULIN GENE EXPRESSION BY ANTI-SENSE RNA IN MOUSE L CELLS.", SYMPOSIUM ON GENE TRANSFER AND GENE THERAPY HELD AT THE 17TH ANNUAL MEETINGS OF THE UCLA SYMPOSIA ON MOLECULAR AND CELLULAR BIOLOGY, TAMARRON, COLORADO, USA, FEBRUARY 6-12, 1988. J CELL BIOCHEM SUPPL 0 (12 PART B), pages 202 *
See also references of WO9314769A1 *

Also Published As

Publication number Publication date
NO942680L (en) 1994-08-24
HU9402188D0 (en) 1994-09-28
CA2126692A1 (en) 1993-08-05
BR9307844A (en) 1996-01-09
WO1993014769A1 (en) 1993-08-05
EP0626852A1 (en) 1994-12-07
JPH07503612A (en) 1995-04-20
AU3598293A (en) 1993-09-01
CZ178394A3 (en) 1995-03-15
HUT67676A (en) 1995-04-28
NO942680D0 (en) 1994-07-15

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Legal Events

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Effective date: 19960131

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Effective date: 19980804