BR9306796A - Polipeptidio bloqueador dos canais de cálcio obtido a partir de agelenopsis aperta - Google Patents

Polipeptidio bloqueador dos canais de cálcio obtido a partir de agelenopsis aperta

Info

Publication number
BR9306796A
BR9306796A BR9306796A BR9306796A BR9306796A BR 9306796 A BR9306796 A BR 9306796A BR 9306796 A BR9306796 A BR 9306796A BR 9306796 A BR9306796 A BR 9306796A BR 9306796 A BR9306796 A BR 9306796A
Authority
BR
Brazil
Prior art keywords
pct
agelenopsis
calcium channel
squeeze
channel blocking
Prior art date
Application number
BR9306796A
Other languages
English (en)
Inventor
Robert Alfred Volkmann
Douglas Phillips
Nicholas Alex Saccomano
Original Assignee
Pfizer
Nps Pharma Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer, Nps Pharma Inc filed Critical Pfizer
Publication of BR9306796A publication Critical patent/BR9306796A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/43504—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates
    • C07K14/43513—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates from arachnidae
    • C07K14/43518—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates from arachnidae from spiders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
BR9306796A 1992-07-27 1993-06-10 Polipeptidio bloqueador dos canais de cálcio obtido a partir de agelenopsis aperta BR9306796A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US91953892A 1992-07-27 1992-07-27
PCT/US1993/005392 WO1994002511A1 (en) 1992-07-27 1993-06-10 Calcium channel blocking polypeptide from agelenopsis aperta

Publications (1)

Publication Number Publication Date
BR9306796A true BR9306796A (pt) 1998-12-08

Family

ID=25442279

Family Applications (1)

Application Number Title Priority Date Filing Date
BR9306796A BR9306796A (pt) 1992-07-27 1993-06-10 Polipeptidio bloqueador dos canais de cálcio obtido a partir de agelenopsis aperta

Country Status (28)

Country Link
US (1) US5599559A (pt)
EP (1) EP0656905B1 (pt)
JP (1) JP2571197B2 (pt)
KR (1) KR950702577A (pt)
CN (1) CN1086824A (pt)
AT (1) ATE157672T1 (pt)
AU (1) AU662066B2 (pt)
BR (1) BR9306796A (pt)
CA (1) CA2139947C (pt)
CZ (1) CZ281539B6 (pt)
DE (1) DE69313650T2 (pt)
DK (1) DK0656905T3 (pt)
ES (1) ES2105284T3 (pt)
FI (1) FI933349A (pt)
GR (1) GR3024637T3 (pt)
HR (1) HRP931050B1 (pt)
HU (1) HU213353B (pt)
IL (1) IL106424A0 (pt)
MX (1) MX9304497A (pt)
MY (1) MY131356A (pt)
NZ (1) NZ253611A (pt)
PL (1) PL307258A1 (pt)
RU (1) RU2104286C1 (pt)
SK (1) SK10395A3 (pt)
TW (1) TW271442B (pt)
WO (1) WO1994002511A1 (pt)
YU (1) YU51593A (pt)
ZA (1) ZA935370B (pt)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5874236A (en) * 1988-04-04 1999-02-23 Sibia Neurosciences. Inc. DNA encoding human calcium channel α-1A, β1, β-2, and β-4 subunits, and assays using cells that express the subunits
US6653097B1 (en) 1991-08-15 2003-11-25 Merck & Co., Inc. Human calcium channel compositions and methods
US5846757A (en) * 1988-04-04 1998-12-08 Sibia Neurosciences, Inc. Human calcium channel α1, α2, and β subunits and assays using them
US5876958A (en) * 1988-04-04 1999-03-02 Sibia Neurosciences, Inc. Assays of cells expressing human calcium channels containing α1 β subunits
US5407820A (en) * 1988-04-04 1995-04-18 The Salk Institute Biotechnology/Industrial Associates, Inc. Calcium channel α-2 subunit DNAs and cells expressing them
CA1341170C (en) 1988-04-04 2001-01-16 Steven B. Ellis Calcium channel compositions and methods
US6096514A (en) * 1988-04-04 2000-08-01 Sibia Neurosciences, Inc. Human calcium channel compositions and methods
US6387696B1 (en) 1988-04-04 2002-05-14 Merck & Co., Inc. Human calcium channel compositions and methods
US20040018510A1 (en) 1990-11-08 2004-01-29 Merck & Co., Inc. Human calcium channel compositions and methods
US6090623A (en) * 1993-08-11 2000-07-18 Merck & Co., Inc. Recombinant human calcium channel β4 subunits
ES2075796B1 (es) * 1993-08-17 1996-03-01 Pfizer Polipeptido de la agelenopsis aperta bloqueante de los canales de ca lcio
ES2239338T5 (es) 1995-09-29 2013-05-31 Vegenics Pty Ltd Genes regulados y sus usos
CA2263890C (en) 1996-08-23 2013-05-14 Ludwig Institute For Cancer Research Recombinant vascular endothelial cell growth factor d (vegf-d)
US6528630B1 (en) 1997-12-03 2003-03-04 Merck & Co., Inc. Calcium channel compositions and methods
EP1870098A3 (en) * 1998-07-10 2010-07-07 Novartis Ag Combined use of valsartan and calcium channel blockers for therapeutic purposes
US8299211B2 (en) * 2005-09-30 2012-10-30 The Board Of Trustees Of The University Of Illinois Peptides and regulation of calcium channels
CN103768469A (zh) * 2012-10-23 2014-05-07 葛继云 一种治疗妇科炎症的中药组合物及其制备方法和用途

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4925664A (en) * 1986-10-20 1990-05-15 University Of Utah Spider toxins and methods for their use as blockers of calcium channels and amino acid receptor function
US5064657A (en) * 1986-10-20 1991-11-12 University Of Utah Spider toxins and methods for their use as blockers of amino acid receptor function
US5196204A (en) * 1986-10-20 1993-03-23 University Of Utah Research Foundation Spider toxins and methods for their use as blockers of calcium channels and amino acid receptor function
US5122596A (en) * 1989-09-29 1992-06-16 Pfizer Inc. Polypeptides useful as blockers of calcium channels

Also Published As

Publication number Publication date
JP2571197B2 (ja) 1997-01-16
CZ9500200A3 (en) 1995-10-18
FI933349A (fi) 1994-01-28
EP0656905B1 (en) 1997-09-03
HU9302158D0 (en) 1993-11-29
CA2139947C (en) 1998-06-30
AU4407893A (en) 1994-02-14
DK0656905T3 (da) 1997-10-20
IL106424A0 (en) 1993-11-15
AU662066B2 (en) 1995-08-17
NZ253611A (en) 1996-09-25
PL307258A1 (en) 1995-05-15
MX9304497A (es) 1994-04-29
RU95105340A (ru) 1996-10-27
YU51593A (sh) 1997-01-08
CN1086824A (zh) 1994-05-18
US5599559A (en) 1997-02-04
ES2105284T3 (es) 1997-10-16
HRP931050B1 (en) 1999-04-30
CA2139947A1 (en) 1994-02-03
KR950702577A (ko) 1995-07-29
ZA935370B (en) 1995-01-26
ATE157672T1 (de) 1997-09-15
SK10395A3 (en) 1995-06-07
JPH07504685A (ja) 1995-05-25
MY131356A (en) 2007-08-30
RU2104286C1 (ru) 1998-02-10
DE69313650D1 (en) 1997-10-09
HUT67467A (en) 1995-04-28
GR3024637T3 (en) 1997-12-31
FI933349A0 (fi) 1993-07-26
WO1994002511A1 (en) 1994-02-03
DE69313650T2 (de) 1998-01-08
HRP931050A2 (en) 1996-12-31
HU213353B (en) 1997-05-28
TW271442B (pt) 1996-03-01
CZ281539B6 (cs) 1996-10-16
EP0656905A1 (en) 1995-06-14

Similar Documents

Publication Publication Date Title
BR9306796A (pt) Polipeptidio bloqueador dos canais de cálcio obtido a partir de agelenopsis aperta
MX9302925A (es) Polipeptidos de bloqueo de canales del calcio a partir de filistata hibernalis.
BR9307363A (pt) Polipeptídeos bloqueadores dos canais de cálcio derivados de theraphosidae aphonopelma
NO950293L (no) Kalsiumkanalblokkerende polypeptid fra Agelenopsis aperta
ES2075796A1 (es) Polipeptido de la agelenopsis aperta bloqueante de los canales de ca lcio

Legal Events

Date Code Title Description
EG Technical examination (opinion): publication of technical examination (opinion)
FC Decision: refusal
FC Decision: refusal