BR9206404A - Heteroaril-polimiaminas sintéticas como antagonistas de neurotransmissores aminoácidos excitadores - Google Patents
Heteroaril-polimiaminas sintéticas como antagonistas de neurotransmissores aminoácidos excitadoresInfo
- Publication number
- BR9206404A BR9206404A BR9206404A BR9206404A BR9206404A BR 9206404 A BR9206404 A BR 9206404A BR 9206404 A BR9206404 A BR 9206404A BR 9206404 A BR9206404 A BR 9206404A BR 9206404 A BR9206404 A BR 9206404A
- Authority
- BR
- Brazil
- Prior art keywords
- polyamines
- antagonists
- heteroaryl
- synthetic
- amino acid
- Prior art date
Links
- 239000005557 antagonist Substances 0.000 title 1
- 230000002461 excitatory amino acid Effects 0.000 title 1
- 239000003257 excitatory amino acid Substances 0.000 title 1
- 239000002858 neurotransmitter agent Substances 0.000 title 1
- 229920000768 polyamine Polymers 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/81—Amides; Imides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
- C07D209/18—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
- C07D209/18—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D209/20—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals substituted additionally by nitrogen atoms, e.g. tryptophane
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
- C07D209/42—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/54—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/56—Amides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/81—Amides; Imides
- C07D213/82—Amides; Imides in position 3
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/12—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D215/14—Radicals substituted by oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
- C07D215/50—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 4
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
- C07D215/54—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
- C07D241/36—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings condensed with carbocyclic rings or ring systems
- C07D241/38—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings condensed with carbocyclic rings or ring systems with only hydrogen or carbon atoms directly attached to the ring nitrogen atoms
- C07D241/40—Benzopyrazines
- C07D241/42—Benzopyrazines with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
- C07D241/36—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings condensed with carbocyclic rings or ring systems
- C07D241/38—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings condensed with carbocyclic rings or ring systems with only hydrogen or carbon atoms directly attached to the ring nitrogen atoms
- C07D241/40—Benzopyrazines
- C07D241/44—Benzopyrazines with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F17/00—Metallocenes
- C07F17/02—Metallocenes of metals of Groups 8, 9 or 10 of the Periodic Table
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Indole Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US07/749,038 US5185369A (en) | 1991-08-23 | 1991-08-23 | Synthetic heteroaryl polyamines as excitatory amino acid neurotransmitter antagonists |
| PCT/US1992/006598 WO1993004041A1 (en) | 1991-08-23 | 1992-08-13 | Synthetic heteroaryl polyamines as excitatory amino acid neurotransmitter antagonists |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR9206404A true BR9206404A (pt) | 1994-12-27 |
Family
ID=25011971
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR9206404A BR9206404A (pt) | 1991-08-23 | 1992-08-13 | Heteroaril-polimiaminas sintéticas como antagonistas de neurotransmissores aminoácidos excitadores |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US5185369A (pt) |
| EP (1) | EP0642496A1 (pt) |
| JP (1) | JPH06505997A (pt) |
| CN (1) | CN1071915A (pt) |
| AU (1) | AU2448992A (pt) |
| BR (1) | BR9206404A (pt) |
| CA (1) | CA2114935A1 (pt) |
| CZ (1) | CZ40294A3 (pt) |
| FI (1) | FI940834A (pt) |
| HU (1) | HU9400506D0 (pt) |
| IL (1) | IL102879A0 (pt) |
| MX (1) | MX9204870A (pt) |
| PT (1) | PT100802A (pt) |
| WO (1) | WO1993004041A1 (pt) |
| ZA (1) | ZA926315B (pt) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6017965A (en) * | 1993-02-08 | 2000-01-25 | Nps Pharmaceuticals, Inc. | Compounds active at a novel site on receptor-operated calcium channels useful for treatment of neurological disorders and diseases |
| US7087765B2 (en) * | 1995-06-07 | 2006-08-08 | Nps Pharmaceuticals, Inc. | Compounds active at a novel site on receptor-operated calcium channels useful for treatment of neurological disorders and diseases |
| US6211245B1 (en) | 1993-02-08 | 2001-04-03 | Nps Pharmaceuticals, Inc. | Compounds active at a novel site on receptor-operated calcium channels useful for treatment of neurological disorders and diseases |
| US6071970A (en) * | 1993-02-08 | 2000-06-06 | Nps Pharmaceuticals, Inc. | Compounds active at a novel site on receptor-operated calcium channels useful for treatment of neurological disorders and diseases |
| US6750244B2 (en) | 1993-02-08 | 2004-06-15 | Nps Pharmaceuticals, Inc. | Compounds active at a novel site on receptor-operated calcium channels useful for treatment of neurological disorders and diseases |
| ATE346595T1 (de) * | 1994-02-08 | 2006-12-15 | Nps Pharma Inc | An einer neuen stelle von rezeptorabhängigen kalziumkanälen wirkende verbindungen zur behandlung von neurologischen erkrankungen |
| US5688764A (en) * | 1995-02-17 | 1997-11-18 | Nps Pharmaceuticals, Inc. | Insecticidal peptides from spider venom |
| US5874298A (en) * | 1995-02-17 | 1999-02-23 | Nps Pharmaceuticals, Inc. | Insecticidal toxins from Bracon hebetor nucleic acid encoding said toxin and methods of use |
| US5674846A (en) * | 1996-09-04 | 1997-10-07 | Nps Pharmaceuticals, Inc. | Insecticidal peptides from Segestria sp. spider venom |
| JP3545639B2 (ja) * | 1998-05-14 | 2004-07-21 | 花王株式会社 | ポリアミン |
| WO2000066175A2 (en) * | 1999-04-30 | 2000-11-09 | Slil Biomedical Corporation | Conjugates as therapies for cancer and prostate diseases |
| JP2005506354A (ja) * | 2001-10-16 | 2005-03-03 | スリル バイオメディカル コーポレイション | 癌治療のためのオリゴアミン化合物およびその誘導体 |
| CN103073448B (zh) * | 2012-12-29 | 2015-11-18 | 河南大学 | 含芳环结构的多胺衍生物及其制备方法和应用 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DD298412A5 (de) * | 1989-04-28 | 1992-02-20 | ������@���Kk�� | Verfahren zur herstellung von polypeptiden, die geeignet sind als antagonisten exzitatorischer aminosaeure-neurotransmitter und/oder blocker der calciumkanaele |
| US5037846A (en) * | 1990-01-02 | 1991-08-06 | Pfizer Inc. | Indolyl-3 polyamines and their use as antagonists of excitatory amino acid neurotransmitters |
-
1991
- 1991-08-23 US US07/749,038 patent/US5185369A/en not_active Expired - Fee Related
-
1992
- 1992-08-13 EP EP92918095A patent/EP0642496A1/en not_active Withdrawn
- 1992-08-13 JP JP5504353A patent/JPH06505997A/ja active Pending
- 1992-08-13 BR BR9206404A patent/BR9206404A/pt not_active Application Discontinuation
- 1992-08-13 CA CA002114935A patent/CA2114935A1/en not_active Abandoned
- 1992-08-13 WO PCT/US1992/006598 patent/WO1993004041A1/en not_active Application Discontinuation
- 1992-08-13 HU HU9400506A patent/HU9400506D0/hu unknown
- 1992-08-13 AU AU24489/92A patent/AU2448992A/en not_active Abandoned
- 1992-08-13 CZ CS94402A patent/CZ40294A3/cs unknown
- 1992-08-20 IL IL102879A patent/IL102879A0/xx unknown
- 1992-08-21 PT PT100802A patent/PT100802A/pt not_active Application Discontinuation
- 1992-08-21 ZA ZA926315A patent/ZA926315B/xx unknown
- 1992-08-21 MX MX9204870A patent/MX9204870A/es unknown
- 1992-08-22 CN CN92110870A patent/CN1071915A/zh active Pending
-
1994
- 1994-02-22 FI FI940834A patent/FI940834A/fi not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| MX9204870A (es) | 1993-04-01 |
| CA2114935A1 (en) | 1993-03-04 |
| AU2448992A (en) | 1993-03-16 |
| CZ40294A3 (en) | 1994-11-16 |
| FI940834A0 (fi) | 1994-02-22 |
| EP0642496A1 (en) | 1995-03-15 |
| US5185369A (en) | 1993-02-09 |
| WO1993004041A1 (en) | 1993-03-04 |
| FI940834A (fi) | 1994-02-22 |
| JPH06505997A (ja) | 1994-07-07 |
| HU9400506D0 (en) | 1994-05-30 |
| IL102879A0 (en) | 1993-01-31 |
| PT100802A (pt) | 1993-09-30 |
| ZA926315B (en) | 1994-02-21 |
| CN1071915A (zh) | 1993-05-12 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| PT94181A (pt) | Processo para a preparacao de heterociclos com 6 membros imidazo-condensados substituidos uteis como antagonistas de angiotensina ii | |
| NO944578D0 (no) | Eksitatoriske aminosyre reseptorantagonister | |
| DK340088D0 (da) | Aminosyrederivater | |
| DE3855981D1 (de) | Zerstäubungstarget aus Mo-Ta oder W-Ta | |
| DK0696577T3 (da) | Syntetiske excitatoriske aminosyrer | |
| DK286389A (da) | Aminosyrederivater | |
| DK96889D0 (da) | Aminosyrederivater | |
| BR9206404A (pt) | Heteroaril-polimiaminas sintéticas como antagonistas de neurotransmissores aminoácidos excitadores | |
| EP0432994A3 (en) | Excitatory amino acid antagonists as anti-emetic drugs | |
| BR9206403A (pt) | Aril-poliaminas sintéticas como antagonistas de neurotransmissores aminoácidos excitadores | |
| ES2066035T3 (es) | Antagonistas de aminoacidos estimulantes. | |
| BR9611509A (pt) | Antagonistas de receptores de aminoácidos excitativos | |
| DK530888A (da) | Leukotrien -ltd4- og - ltb4-antagonister | |
| DK139185A (da) | Substituerede aminosyrer | |
| DK523288A (da) | Aminosyrederivater | |
| BR8804208A (pt) | Fivela de resina sintetica | |
| MX9205216A (es) | Derivados de amida substituida de antagonistas de piperizinilcan-forsulfonil oxitocina | |
| NO940605D0 (no) | Syntetiske aryl-polyaminer som antagonister for eksitatoriske aminosyre-neurotransmittere | |
| NO940604D0 (no) | Syntetiske heteroaryl-polyaminer som antagonister for eksitatoriske aminosyre-neurotransmittere | |
| FR2621722B1 (fr) | Distributeur de bordereaux pmu | |
| ZA917B (en) | Polyamines useful as antagonists of excitatory amino acid neurotransmitters | |
| MX9203743A (es) | Acidos tiofenilalcanoicos utiles como antagonistas de leucotrieno | |
| BR8700292A (pt) | Injetor-dosador pneumatico de leito fluidizado denso | |
| KR900700012A (ko) | 엽면 살포제 | |
| BR1100494A (pt) | Antagonistas de ige |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| EE | Request for examination | ||
| EG | Technical examination (opinion): publication of technical examination (opinion) | ||
| FC | Decision: refusal | ||
| FC | Decision: refusal |