BR7504996A - Processo para a producao de acido de warfarina microcristalina - Google Patents

Processo para a producao de acido de warfarina microcristalina

Info

Publication number
BR7504996A
BR7504996A BR7504996A BR7504996A BR7504996A BR 7504996 A BR7504996 A BR 7504996A BR 7504996 A BR7504996 A BR 7504996A BR 7504996 A BR7504996 A BR 7504996A BR 7504996 A BR7504996 A BR 7504996A
Authority
BR
Brazil
Prior art keywords
warfarine
acid
production
micro crystalline
crystalline
Prior art date
Application number
BR7504996A
Other languages
English (en)
Portuguese (pt)
Inventor
N Badran
Original Assignee
Carter Wallace
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Carter Wallace filed Critical Carter Wallace
Publication of BR7504996A publication Critical patent/BR7504996A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/42—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms in positions 2 and 4
    • C07D311/44—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms in positions 2 and 4 with one hydrogen atom in position 3
    • C07D311/46—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms in positions 2 and 4 with one hydrogen atom in position 3 unsubstituted in the carbocyclic ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Hematology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrane Compounds (AREA)
BR7504996A 1974-08-13 1975-08-05 Processo para a producao de acido de warfarina microcristalina BR7504996A (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/496,932 US4113744A (en) 1974-08-13 1974-08-13 Microcrystalline 3-(alpha-acetonylbenzyl)-4-hydroxycoumarin (warfarin) and methods of making

Publications (1)

Publication Number Publication Date
BR7504996A true BR7504996A (pt) 1976-08-31

Family

ID=23974780

Family Applications (1)

Application Number Title Priority Date Filing Date
BR7504996A BR7504996A (pt) 1974-08-13 1975-08-05 Processo para a producao de acido de warfarina microcristalina

Country Status (13)

Country Link
US (1) US4113744A (OSRAM)
JP (1) JPS5835967B2 (OSRAM)
BE (1) BE832395A (OSRAM)
BR (1) BR7504996A (OSRAM)
CA (1) CA1077502A (OSRAM)
DE (1) DE2535228A1 (OSRAM)
ES (1) ES440221A1 (OSRAM)
FR (1) FR2281754A1 (OSRAM)
GB (1) GB1513399A (OSRAM)
IN (1) IN141166B (OSRAM)
LU (1) LU73199A1 (OSRAM)
NL (1) NL7509661A (OSRAM)
ZA (1) ZA754795B (OSRAM)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5696274A (en) * 1995-12-28 1997-12-09 Hoechst Celanese Corporation Syntheses based on 2-hydroxyacetophenone
AU4068299A (en) * 1998-03-30 1999-10-18 Sloan-Kettering Institute For Cancer Research Bismuth-213 generator and uses thereof
US6512005B2 (en) 2001-02-28 2003-01-28 Taro Pharmaceutical Industries, Ltd. Process for synthesis of pure warfarin acid, warfarin alkali metal salts and corresponding clathrates
US6673944B2 (en) 2001-02-28 2004-01-06 Taro Pharmaceutical Industries, Ltd. Preparation of warfarin sodium from warfarin acid
US6610862B2 (en) 2001-02-28 2003-08-26 Taro Pharmaceutical Industries Ltd. Preparation of warfarin sodium from warfarin sodium-2-propanol clathrate by solvent expulsion
CA2439488A1 (en) * 2001-02-28 2002-09-12 Taro Pharmaceutical Industries Ltd. Process for purification of warfarin acid, warfarin alkali metal salts and corresponding clathrates
EP1589930A2 (en) * 2003-01-08 2005-11-02 Flacco-Nesselroad Family Trust Combination therapy for anticoagulation
GB0329303D0 (en) * 2003-12-18 2004-01-21 Whelan Ian P Rodenticide bait system
GB2635614A (en) * 2023-07-22 2025-05-21 Liqmeds Worldwide Ltd A ready-to-use oral liquid formulation of warfarin sodium
WO2025022245A1 (en) * 2023-07-22 2025-01-30 Liqmeds Worldwide Limited A ready-to-use oral liquid formulation of warfarin sodium
CN117169390B (zh) * 2023-10-18 2024-05-03 宁波市疾病预防控制中心(宁波市健康教育与促进中心) 一种测定血液中安妥的方法、试剂盒及应用

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2666064A (en) * 1951-07-10 1954-01-12 S B Penick & Company Inc Manufacture of 3-(alpha-phenyl-beta-acetylethyl)-4-hydroxycoumarin
US2777859A (en) * 1953-02-05 1957-01-15 Wisconsin Alumni Res Found Warfarin-alkali metal derivatives and processes of preparing the same
US2752360A (en) * 1953-03-23 1956-06-26 S B Penick & Company Inc Improvement in the manufacture of 3-substituted 4-hydroxycoumarins
US2932652A (en) * 1957-02-11 1960-04-12 Nicholas M Molnar 3-(1'-(alpha-naphthyl) 3'-oxo-butyl) 4-hydroxy coumarin and salts thereof

Also Published As

Publication number Publication date
LU73199A1 (OSRAM) 1976-08-13
CA1077502A (en) 1980-05-13
NL7509661A (nl) 1976-02-17
IN141166B (OSRAM) 1977-01-29
JPS5835967B2 (ja) 1983-08-05
JPS5141361A (OSRAM) 1976-04-07
AU8356175A (en) 1977-02-03
GB1513399A (en) 1978-06-07
DE2535228A1 (de) 1976-02-26
ZA754795B (en) 1977-03-30
FR2281754B1 (OSRAM) 1978-11-10
BE832395A (fr) 1976-02-13
US4113744A (en) 1978-09-12
FR2281754A1 (fr) 1976-03-12
ES440221A1 (es) 1977-03-01

Similar Documents

Publication Publication Date Title
BR7406531D0 (pt) Processo aperfeicoado para a recuperacao de produto de acido tereftalico cristalino
BR7408664D0 (pt) Processo para a obtencao de dinitrila de acido malonico
BR7504240A (pt) Processo para a producao de isocianatos a partir de esteres de acidos carbamicos
BR7503729A (pt) Processo para a producao de isocianatos
BR7508170A (pt) Processo para a producao de carbonil-aldimino-metano-fosfanatos
BR7504996A (pt) Processo para a producao de acido de warfarina microcristalina
BR7604336A (pt) Processo para a preparacao de acido sulfurico
BR7500809A (pt) Processo para a preparacao de fluoreto de calcio a partir de acido a partir de acido hexafluorosilisico
BR7505624A (pt) Processo para a producao de finilmetilcarbinol
BR7605592A (pt) Processo para producao de acido tereftalico purificado
BR7403946D0 (pt) Processo para a fabricacao de esteres de acido 5-oxo-carboxilico
BR7604368A (pt) Processo para producao de acido sulfurico
BR7508484A (pt) Processo aperfeicoado para a producao de acido nitrico concentrado
BR7503007A (pt) Processo para a fabricacao de compostos de n-aril-imida de acido 4-amido-1,8-naftalico
BR7705141A (pt) Processo para a producao de cloreto de acido benzenossulfonico
BR7402271D0 (pt) Processo para a fabricacao de esteres de acidos fosforico
BR7407605D0 (pt) Processo para a preparacao de nitrila de acido ciclo-propanocarboxilico
BR7502585A (pt) Processo para a preparacao de acido cianurico
BR7707125A (pt) Processo para a preparacao de acido tereftatilo
BR7500436A (pt) Processo para a producao de n n-dialildicloroacetamida
BR7307283D0 (pt) Processo para a preparacao de imidas de acido naftoileno arilimidazolperidicarbonalico
BR7507584A (pt) Processo para a producao de acosilicio eletromagnetico
BR7508487A (pt) Processo aperfeicoado para a preparacao de acido nitrico concentrado
BR7504253A (pt) Processo para a purificacao de acido fosforico
IT1063993B (it) Processo per la produzione di acido tetrafluoborico concentrato