BR122019021332A2 - - Google Patents
Info
- Publication number
- BR122019021332A2 BR122019021332A2 BR122019021332A BR122019021332A BR122019021332A2 BR 122019021332 A2 BR122019021332 A2 BR 122019021332A2 BR 122019021332 A BR122019021332 A BR 122019021332A BR 122019021332 A BR122019021332 A BR 122019021332A BR 122019021332 A2 BR122019021332 A2 BR 122019021332A2
- Authority
- BR
- Brazil
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D473/00—Heterocyclic compounds containing purine ring systems
- C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
- C07D473/18—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 one oxygen and one nitrogen atom, e.g. guanine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
- A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
- A61K31/7064—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US98820007P | 2007-11-15 | 2007-11-15 | |
| US98819207P | 2007-11-15 | 2007-11-15 | |
| PCT/US2008/012804 WO2009064471A1 (en) | 2007-11-15 | 2008-11-14 | Method of synthesis of morpholino oligomers |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| BR122019021332A2 true BR122019021332A2 (pt) | 2015-05-26 |
| BR122019021332A8 BR122019021332A8 (pt) | 2022-12-06 |
Family
ID=40293764
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR122019021332A BR122019021332A8 (pt) | 2007-11-15 | 2008-11-14 | Processo de síntese de oligômeros de morfolino |
| BRPI0819828A BRPI0819828A8 (pt) | 2007-11-15 | 2008-11-14 | Processo de síntese de oligômeros de morfolino |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI0819828A BRPI0819828A8 (pt) | 2007-11-15 | 2008-11-14 | Processo de síntese de oligômeros de morfolino |
Country Status (14)
| Country | Link |
|---|---|
| EP (1) | EP2207779B1 (pt) |
| JP (3) | JP5512533B2 (pt) |
| KR (1) | KR101617472B1 (pt) |
| CN (1) | CN101861318A (pt) |
| BR (2) | BR122019021332A8 (pt) |
| CA (2) | CA2704261C (pt) |
| DK (1) | DK2207779T3 (pt) |
| ES (1) | ES2479393T3 (pt) |
| HK (1) | HK1144424A1 (pt) |
| HR (1) | HRP20140646T1 (pt) |
| IL (1) | IL205776A0 (pt) |
| MX (1) | MX2010004955A (pt) |
| RU (1) | RU2606627C2 (pt) |
| WO (1) | WO2009064471A1 (pt) |
Families Citing this family (86)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2852549T3 (es) | 2005-02-09 | 2021-09-13 | Sarepta Therapeutics Inc | Composición antisentido para tratamiento de la atrofia muscular |
| US8067571B2 (en) | 2005-07-13 | 2011-11-29 | Avi Biopharma, Inc. | Antibacterial antisense oligonucleotide and method |
| CA2764158A1 (en) | 2009-06-01 | 2010-12-09 | Halo-Bio Rnai Therapeutics, Inc. | Polynucleotides for multivalent rna interference, compositions and methods of use thereof |
| US8697858B2 (en) | 2009-11-13 | 2014-04-15 | Sarepta Therapeutics, Inc. | Antisense antiviral compound and method for treating influenza viral infection |
| NZ603606A (en) | 2010-05-28 | 2015-06-26 | Sarepta Therapeutics Inc | Oligonucleotide analogues having modified intersubunit linkages and/or terminal groups |
| TWI541024B (zh) | 2010-09-01 | 2016-07-11 | 日本新藥股份有限公司 | 反義核酸 |
| US10017763B2 (en) | 2010-09-03 | 2018-07-10 | Sarepta Therapeutics, Inc. | dsRNA molecules comprising oligonucleotide analogs having modified intersubunit linkages and/or terminal groups |
| ES2607603T3 (es) * | 2010-09-30 | 2017-04-03 | Nippon Shinyaku Co., Ltd. | Derivado de ácido morfolino nucleico |
| EP2638161A1 (en) | 2010-11-12 | 2013-09-18 | Sarepta Therapeutics, Inc. | Antisense antibacterial compounds and methods |
| CN103619356B (zh) | 2011-05-05 | 2017-09-12 | 萨勒普塔医疗公司 | 肽寡核苷酸缀合物 |
| US10100305B2 (en) | 2011-07-15 | 2018-10-16 | Sarepta Therapeutics, Inc. | Methods and compositions for manipulating translation of protein isoforms from alternative initiation of start sites |
| US20130085139A1 (en) | 2011-10-04 | 2013-04-04 | Royal Holloway And Bedford New College | Oligomers |
| KR20140097398A (ko) | 2011-11-18 | 2014-08-06 | 사렙타 쎄러퓨틱스, 인코퍼레이티드 | 기능적으로-변형된 올리고뉴클레오티드 및 이의 서브유니트 |
| US10066228B2 (en) | 2011-11-30 | 2018-09-04 | Sarepta Therapeutics, Inc. | Oligonucleotides for treating expanded repeat diseases |
| EP2785840B8 (en) | 2011-11-30 | 2019-05-22 | Sarepta Therapeutics, Inc. | Induced exon inclusion in spinal muscle atrophy |
| LT2788487T (lt) | 2011-12-08 | 2018-09-10 | Sarepta Therapeutics, Inc. | Oligonukleotido analogai, nukreipti į žmogaus lmna |
| IN2014DN06220A (pt) * | 2011-12-28 | 2015-10-23 | Nippon Shinyaku Co Ltd | |
| US9920085B2 (en) | 2012-03-20 | 2018-03-20 | Sarepta Therapeutics, Inc. | Boronic acid conjugates of oligonucleotide analogues |
| CN102702265A (zh) * | 2012-05-14 | 2012-10-03 | 天津特安化学科技有限公司 | 一种固相合成磷酰二胺吗啉代寡核苷酸及方法 |
| WO2014113540A1 (en) | 2013-01-16 | 2014-07-24 | Iowa State University Research Foundation, Inc. | A deep intronic target for splicing correction on spinal muscular atrophy gene |
| EP3015467A4 (en) | 2013-05-24 | 2016-11-02 | Ajinomoto Kk | PROCESS FOR THE PRODUCTION OF MORPHOLINO-OLIGONUCLEOTIDE |
| AU2014317961B2 (en) | 2013-09-05 | 2020-07-30 | Murdoch University | Antisense-induced exon2 inclusion in acid alpha-glucosidase |
| EP3052512A4 (en) | 2013-09-30 | 2017-02-22 | Geron Corporation | Phosphorodiamidate backbone linkage for oligonucleotides |
| RU2702424C2 (ru) | 2014-03-12 | 2019-10-08 | Ниппон Синяку Ко., Лтд. | Антисмысловые нуклеиновые кислоты |
| CA2948373A1 (en) | 2014-05-16 | 2015-11-19 | Oregon State University | Antisense antibacterial compounds and methods |
| CA2948568A1 (en) | 2014-05-19 | 2015-11-26 | David Greenberg | Antisense antibacterial compounds and methods |
| TWI721461B (zh) | 2014-06-17 | 2021-03-11 | 日商日本新藥股份有限公司 | 反義核酸 |
| EP3208277A4 (en) * | 2014-10-14 | 2018-06-13 | Ajinomoto Co., Inc. | Morpholino oligonucleotide manufacturing method |
| AU2015372560B2 (en) | 2014-12-31 | 2021-12-02 | Board Of Regents, The University Of Texas System | Antisense antibacterial compounds and methods |
| MA41795A (fr) | 2015-03-18 | 2018-01-23 | Sarepta Therapeutics Inc | Exclusion d'un exon induite par des composés antisens dans la myostatine |
| KR20240035901A (ko) | 2015-05-19 | 2024-03-18 | 사렙타 쎄러퓨틱스 인코퍼레이티드 | 펩티드 올리고뉴클레오티드 콘주게이트 |
| EP3302497A4 (en) | 2015-06-01 | 2019-01-16 | Sarepta Therapeutics, Inc. | EXCLUSION OF EXON INDUCED PAT TECHNOLOGY ANTISENSE IN COLLAGEN TYPE VII |
| EP3302489A4 (en) | 2015-06-04 | 2019-02-06 | Sarepta Therapeutics, Inc. | METHOD AND COMPOUNDS FOR THE TREATMENT OF DISEASES AND SUFFERING IN CONNECTION WITH LYMPHOCYTES |
| UA123995C2 (uk) | 2015-08-05 | 2021-07-07 | ЕЙСАЙ Ар ЕНД Ді МЕНЕДЖМЕНТ КО., ЛТД. | Хіральні реагенти для одержання гомогенних олігомерів |
| BR112018003784A2 (pt) | 2015-08-24 | 2018-09-25 | Halo-Bio Rnai Therapeutics, Inc. | nanopartículas de polinucleotídeo para a modulação da expressão gênica e sua utilização |
| MY185390A (en) | 2015-09-15 | 2021-05-17 | Nippon Shinyaku Co Ltd | Antisense nucleic acids |
| WO2017047741A1 (ja) | 2015-09-16 | 2017-03-23 | 日本新薬株式会社 | 筋萎縮症治療用アンチセンス核酸 |
| EP3359668A4 (en) | 2015-10-09 | 2019-06-05 | Sarepta Therapeutics, Inc. | COMPOSITIONS AND METHODS OF TREATING DUCHENNE MUSCLE DYSTROPHY AND ASSOCIATED ILLNESSES THEREOF |
| EA201891419A1 (ru) | 2015-12-15 | 2019-01-31 | Сарепта Терапьютикс, Инк. | Пептид-олигонуклеотидные конъюгаты |
| CA3010084A1 (en) | 2015-12-23 | 2017-06-29 | Oregon State University | Antisense antibacterial compounds and methods |
| JP7393121B2 (ja) | 2015-12-23 | 2023-12-06 | オレゴン ステイト ユニバーシティー | アンチセンス抗菌化合物および方法 |
| EP3445405A4 (en) | 2016-04-18 | 2019-12-18 | Sarepta Therapeutics, Inc. | ANTISENSE OLIGOMERS AND METHOD FOR USE THEREOF TO TREAT DISEASES RELATING TO THE ACID ALPHA GLUCOSIDASE GENE |
| BR112018072279A2 (pt) | 2016-04-29 | 2019-02-12 | Sarepta Therapeutics, Inc. | análogos de oligonucleotídeo tendo como alvo lmna humana |
| CN109563114B (zh) | 2016-05-24 | 2022-08-12 | 萨勒普塔医疗公司 | 用于制备寡聚物的方法 |
| IL263044B1 (en) | 2016-05-24 | 2024-02-01 | Sarepta Therapeutics Inc | Processes for the preparation of phosphorodiamidate morpholino oligomers |
| MA45362A (fr) | 2016-05-24 | 2019-04-10 | Sarepta Therapeutics Inc | Procédés de préparation d'oligomères morpholino de phosphorodiamidate |
| DK3464306T3 (da) | 2016-05-24 | 2024-05-21 | Sarepta Therapeutics Inc | Fremgangsmåder til fremstilling af phosphorodiamidat-morpholino-oligomerer |
| US11472824B2 (en) | 2016-05-24 | 2022-10-18 | Sarepta Therapeutics, Inc. | Processes for preparing phosphorodiamidate morpholino oligomers |
| AU2017278699A1 (en) | 2016-05-24 | 2018-11-15 | Sarepta Therapeutics, Inc. | Pharmaceutical composition comprising Eteplirsen |
| CA3024153A1 (en) * | 2016-06-30 | 2017-11-30 | Sarepta Therapeutics, Inc. | Processes for preparing phosphorodiamidate morpholino oligomers |
| JP2019534862A (ja) * | 2016-09-20 | 2019-12-05 | ザ リージェンツ オブ ザ ユニヴァーシティ オブ コロラド，ア ボディ コーポレイト | ホスホルアミダイト化学を使用する骨格修飾モルホリノオリゴヌクレオチド及びキメラの合成 |
| KR102639633B1 (ko) | 2016-12-19 | 2024-02-26 | 사렙타 쎄러퓨틱스 인코퍼레이티드 | 근육 이상증에 대한 엑손 스킵핑 올리고머 결합체 |
| NZ755416A (en) | 2016-12-19 | 2023-05-26 | Sarepta Therapeutics Inc | Exon skipping oligomer conjugates for muscular dystrophy |
| IL267246B2 (en) | 2016-12-19 | 2023-03-01 | Sarepta Therapeutics Inc | Exon-skipping oligomer conjugates for muscular dystrophy |
| EP3612215A4 (en) | 2017-04-20 | 2021-05-26 | aTyr Pharma, Inc. | COMPOSITIONS AND METHODS OF TREATMENT OF Pneumonia |
| EA201991450A1 (ru) | 2017-09-22 | 2019-12-30 | Сарепта Терапьютикс, Инк. | Конъюгаты олигомеров для пропуска экзона при мышечной дистрофии |
| WO2019060862A1 (en) * | 2017-09-25 | 2019-03-28 | Sarepta Therapeutics, Inc. | METHODS FOR PREPARING MORPHOLINO PHOSPHORODIAMIDATE OLIGOMERS VIA FAST FLOW SYNTHESIS |
| US11555189B2 (en) | 2017-10-18 | 2023-01-17 | Sarepta Therapeutics, Inc. | Antisense oligomer compounds |
| JP7394749B2 (ja) | 2018-05-10 | 2023-12-08 | 日本新薬株式会社 | オリゴ核酸化合物の製造方法 |
| US10758629B2 (en) | 2018-05-29 | 2020-09-01 | Sarepta Therapeutics, Inc. | Exon skipping oligomer conjugates for muscular dystrophy |
| EP3806868A4 (en) | 2018-06-13 | 2022-06-22 | Sarepta Therapeutics, Inc. | EXON-SKIPPING OLIGOMERS FOR MUSCULAR DYSTROPHY |
| KR20210023988A (ko) | 2018-06-26 | 2021-03-04 | 니뽄 신야쿠 가부시키가이샤 | 안티센스 올리고뉴클레오티드를 함유하는 조성물 및 듀시엔형 근이영양증의 치료로의 그의 사용 |
| TW202020153A (zh) | 2018-07-27 | 2020-06-01 | 美商薩羅塔治療公司 | 用於肌肉萎縮症之外顯子跳躍寡聚物 |
| EP3894558A1 (en) | 2018-12-13 | 2021-10-20 | Sarepta Therapeutics, Inc. | Exon skipping oligomer conjugates for muscular dystrophy |
| GB201821269D0 (en) | 2018-12-28 | 2019-02-13 | Nippon Shinyaku Co Ltd | Myostatin signal inhibitor |
| WO2021025899A1 (en) | 2019-08-02 | 2021-02-11 | Sarepta Therapeutics, Inc. | Phosphorodiamidate morpholino oligomer pharmaceutical compositions |
| US20230018780A1 (en) | 2019-11-13 | 2023-01-19 | Nippon Shinyaku Co., Ltd. | Method for producing oligonucleic acid compound |
| CA3161589A1 (en) | 2019-11-13 | 2021-05-20 | Nippon Shinyaku Co., Ltd. | Method for producing oligonucleic acid compound |
| IL293997A (en) | 2019-12-19 | 2022-08-01 | Nippon Shinyaku Co Ltd | Antistrand nucleic acids that allow exon skipping |
| CN114901823A (zh) | 2019-12-26 | 2022-08-12 | 日本新药株式会社 | 诱导外显子50的跳读的反义核酸 |
| KR20220145865A (ko) | 2020-02-28 | 2022-10-31 | 니뽄 신야쿠 가부시키가이샤 | 엑손 51의 스키핑을 유도하는 안티센스 핵산 |
| CN116096724A (zh) * | 2020-07-10 | 2023-05-09 | 常州合全药业有限公司 | 用于制备寡核苷酸的方法 |
| CA3218264A1 (en) | 2021-04-28 | 2022-11-03 | Nippon Shinyaku Co., Ltd. | Method for producing oligonucleic acid compound |
| JPWO2022239863A1 (pt) | 2021-05-13 | 2022-11-17 | ||
| KR20240013202A (ko) | 2021-05-28 | 2024-01-30 | 스미토모 파마 가부시키가이샤 | 안티센스 핵산 |
| TW202307208A (zh) | 2021-06-23 | 2023-02-16 | 日商日本新藥股份有限公司 | 反義寡聚物之組合 |
| AU2022306542A1 (en) | 2021-07-08 | 2024-01-18 | Nippon Shinyaku Co., Ltd. | Precipitation suppressing agent |
| TW202308664A (zh) | 2021-07-08 | 2023-03-01 | 日商日本新藥股份有限公司 | 腎毒性減輕劑 |
| WO2023282345A1 (ja) | 2021-07-08 | 2023-01-12 | 日本新薬株式会社 | 腎毒性軽減剤 |
| WO2023026994A1 (ja) | 2021-08-21 | 2023-03-02 | 武田薬品工業株式会社 | ヒトトランスフェリンレセプター結合ペプチド－薬物コンジュゲート |
| WO2023034515A2 (en) | 2021-09-03 | 2023-03-09 | Sarepta Therapeutics, Inc. | Delivery of anitsense oligomers by mirror image peptides |
| WO2023055774A1 (en) | 2021-09-30 | 2023-04-06 | Sarepta Therapeutics, Inc. | Antisense oligonucleotides having one or more abasic units |
| WO2023070086A1 (en) | 2021-10-22 | 2023-04-27 | Sarepta Therapeutics, Inc. | Morpholino oligomers for treatment of peripheral myelin protein 22 related diseases |
| WO2023167908A1 (en) * | 2022-03-01 | 2023-09-07 | Eisai R&D Management Co., Ltd. | Bis-protected, activated guanine monomers |
| WO2024064237A2 (en) | 2022-09-21 | 2024-03-28 | Sarepta Therapeutics, Inc. | Dmd antisense oligonucleotide-mediated exon skipping efficiency |
| CN117586307B (zh) * | 2024-01-19 | 2024-04-16 | 凯莱英生命科学技术(天津)有限公司 | Pmo鸟苷单体的合成方法 |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CH577464A5 (pt) * | 1972-09-22 | 1976-07-15 | Ciba Geigy Ag | |
| US5185444A (en) | 1985-03-15 | 1993-02-09 | Anti-Gene Deveopment Group | Uncharged morpolino-based polymers having phosphorous containing chiral intersubunit linkages |
| EP0962463B1 (en) * | 1989-12-20 | 2002-07-10 | Antivirals Inc. | Uncharged morpholino-based polymers having phosphorus-containing chiral intersubunit linkages |
| WO1991018898A1 (fr) * | 1990-06-01 | 1991-12-12 | Nippon Shinyaku Co., Ltd. | Homologue d'acide nucleique |
| US5510476A (en) | 1994-07-07 | 1996-04-23 | Isis Pharmaceuticals, Inc. | Carbocation scavenging during oligonucleotide synthesis |
| UA48150C2 (uk) * | 1994-11-02 | 2002-08-15 | Ай-Сі-Ен Фармасьютикалз | Похідні амінокислот або аміноспиртів, олігонуклеотид |
| US7790694B2 (en) * | 2005-07-13 | 2010-09-07 | Avi Biopharma Inc. | Antisense antibacterial method and compound |
| SI2735568T1 (en) * | 2006-05-10 | 2018-01-31 | Sarepta Therapeutics, Inc. | Analogues of the oligonucleotide, with cationic links between subunits |
-
2008
- 2008-11-14 CN CN200880116219A patent/CN101861318A/zh active Pending
- 2008-11-14 ES ES08850132.5T patent/ES2479393T3/es active Active
- 2008-11-14 KR KR1020107009620A patent/KR101617472B1/ko active IP Right Grant
- 2008-11-14 MX MX2010004955A patent/MX2010004955A/es active IP Right Grant
- 2008-11-14 EP EP08850132.5A patent/EP2207779B1/en active Active
- 2008-11-14 RU RU2010123958A patent/RU2606627C2/ru not_active Application Discontinuation
- 2008-11-14 BR BR122019021332A patent/BR122019021332A8/pt not_active Application Discontinuation
- 2008-11-14 CA CA2704261A patent/CA2704261C/en active Active
- 2008-11-14 BR BRPI0819828A patent/BRPI0819828A8/pt not_active Application Discontinuation
- 2008-11-14 JP JP2010534042A patent/JP5512533B2/ja active Active
- 2008-11-14 WO PCT/US2008/012804 patent/WO2009064471A1/en active Application Filing
- 2008-11-14 DK DK08850132.5T patent/DK2207779T3/da active
- 2008-11-14 CA CA2884340A patent/CA2884340C/en active Active
-
2010
- 2010-05-13 IL IL205776A patent/IL205776A0/en unknown
- 2010-11-18 HK HK10110758.9A patent/HK1144424A1/xx unknown
-
2014
- 2014-03-26 JP JP2014063314A patent/JP6178744B2/ja active Active
- 2014-07-07 HR HRP20140646AT patent/HRP20140646T1/hr unknown
-
2016
- 2016-06-30 JP JP2016129716A patent/JP2016196494A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| BR122019021332A8 (pt) | 2022-12-06 |
| MX2010004955A (es) | 2010-06-30 |
| KR101617472B1 (ko) | 2016-05-02 |
| IL205776A0 (en) | 2010-11-30 |
| CA2884340A1 (en) | 2009-05-22 |
| JP5512533B2 (ja) | 2014-06-04 |
| EP2207779A1 (en) | 2010-07-21 |
| CN101861318A (zh) | 2010-10-13 |
| AU2008321409B2 (en) | 2014-08-14 |
| RU2606627C2 (ru) | 2017-01-10 |
| KR20100090681A (ko) | 2010-08-16 |
| WO2009064471A1 (en) | 2009-05-22 |
| EP2207779B1 (en) | 2014-04-09 |
| DK2207779T3 (da) | 2014-07-14 |
| JP2011503184A (ja) | 2011-01-27 |
| JP2014159432A (ja) | 2014-09-04 |
| CA2704261C (en) | 2015-05-26 |
| HK1144424A1 (en) | 2011-02-18 |
| BRPI0819828A2 (pt) | 2015-05-26 |
| JP6178744B2 (ja) | 2017-08-09 |
| JP2016196494A (ja) | 2016-11-24 |
| BRPI0819828A8 (pt) | 2022-12-27 |
| CA2884340C (en) | 2017-07-25 |
| RU2010123958A (ru) | 2011-12-20 |
| HRP20140646T1 (hr) | 2014-09-26 |
| ES2479393T3 (es) | 2014-07-24 |
| CA2704261A1 (en) | 2009-05-22 |
| AU2008321409A1 (en) | 2009-05-22 |
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