BR112023026062A2 - Método para preparar um composto - Google Patents
Método para preparar um compostoInfo
- Publication number
- BR112023026062A2 BR112023026062A2 BR112023026062A BR112023026062A BR112023026062A2 BR 112023026062 A2 BR112023026062 A2 BR 112023026062A2 BR 112023026062 A BR112023026062 A BR 112023026062A BR 112023026062 A BR112023026062 A BR 112023026062A BR 112023026062 A2 BR112023026062 A2 BR 112023026062A2
- Authority
- BR
- Brazil
- Prior art keywords
- preparing
- compound
- chelator
- ligands
- purification
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 5
- 150000001875 compounds Chemical class 0.000 title abstract 3
- 229940123769 Xanthine oxidase inhibitor Drugs 0.000 abstract 1
- 230000015572 biosynthetic process Effects 0.000 abstract 1
- 239000002738 chelating agent Substances 0.000 abstract 1
- 238000000605 extraction Methods 0.000 abstract 1
- 239000003446 ligand Substances 0.000 abstract 1
- 238000000746 purification Methods 0.000 abstract 1
- 239000007858 starting material Substances 0.000 abstract 1
- 239000000126 substance Substances 0.000 abstract 1
- 238000003786 synthesis reaction Methods 0.000 abstract 1
- 239000003064 xanthine oxidase inhibitor Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
- C07D209/42—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/08—Indoles; Hydrogenated indoles with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to carbon atoms of the hetero ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Indole Compounds (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
método para preparar um composto. a presente invenção se refere a um método para preparar um intermediário para síntese de um inibidor da xantina oxidase e, mais especificamente, a um método para preparar compostos das fórmulas químicas 2 e 4 usando materiais de partida e ligantes de baixo custo e empregando técnicas de extração e purificação com quelante.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| KR20210087042 | 2021-07-02 | ||
| PCT/KR2022/009544 WO2023277658A1 (ko) | 2021-07-02 | 2022-07-01 | 잔틴 옥시다아제 저해제 합성을 위한 중간체의 제조 방법 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR112023026062A2 true BR112023026062A2 (pt) | 2024-03-05 |
Family
ID=84691985
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR112023026062A BR112023026062A2 (pt) | 2021-07-02 | 2022-07-01 | Método para preparar um composto |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US20240317685A1 (pt) |
| EP (1) | EP4349809A4 (pt) |
| JP (1) | JP2024523604A (pt) |
| KR (1) | KR20230006408A (pt) |
| CN (1) | CN117561237A (pt) |
| AR (1) | AR126353A1 (pt) |
| AU (1) | AU2022302841A1 (pt) |
| BR (1) | BR112023026062A2 (pt) |
| CA (1) | CA3221122A1 (pt) |
| CL (1) | CL2023003910A1 (pt) |
| CO (1) | CO2024001078A2 (pt) |
| MX (1) | MX2023014804A (pt) |
| TW (1) | TWI835186B (pt) |
| WO (1) | WO2023277658A1 (pt) |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TW225535B (pt) * | 1992-11-10 | 1994-06-21 | Hoechst Ag | |
| AU2004296191B2 (en) * | 2003-12-04 | 2010-10-28 | Albany Molecular Research, Inc. | Vinca derivatives |
| TWI423962B (zh) | 2009-10-07 | 2014-01-21 | Lg Life Sciences Ltd | 有效作為黃嘌呤氧化酶抑制劑之新穎化合物、其製備方法及含該化合物之醫藥組成物 |
| CN104341396A (zh) * | 2013-08-08 | 2015-02-11 | 上海医药集团股份有限公司 | 二芳基乙内酰脲衍生物、其制备方法、药物组合物和应用 |
| HUE040489T2 (hu) * | 2014-06-03 | 2019-03-28 | Idorsia Pharmaceuticals Ltd | Pirazolvegyületek és alkalmazásuk t-típusú kalciumcsatorna-blokkolókként |
| CN107286134B (zh) * | 2016-04-11 | 2019-04-12 | 上海勋和医药科技有限公司 | 2，4-二取代嘧啶衍生物作为cdk抑制剂及其应用 |
| TW202128677A (zh) * | 2019-10-30 | 2021-08-01 | 美商米突倍基公司 | Cd38抑制劑 |
-
2022
- 2022-07-01 AR ARP220101725A patent/AR126353A1/es unknown
- 2022-07-01 CA CA3221122A patent/CA3221122A1/en active Pending
- 2022-07-01 AU AU2022302841A patent/AU2022302841A1/en active Pending
- 2022-07-01 EP EP22833711.9A patent/EP4349809A4/en active Pending
- 2022-07-01 BR BR112023026062A patent/BR112023026062A2/pt unknown
- 2022-07-01 US US18/575,630 patent/US20240317685A1/en active Pending
- 2022-07-01 JP JP2023579843A patent/JP2024523604A/ja active Pending
- 2022-07-01 KR KR1020220081195A patent/KR20230006408A/ko not_active Application Discontinuation
- 2022-07-01 MX MX2023014804A patent/MX2023014804A/es unknown
- 2022-07-01 WO PCT/KR2022/009544 patent/WO2023277658A1/ko active Application Filing
- 2022-07-01 CN CN202280044250.8A patent/CN117561237A/zh active Pending
- 2022-07-01 TW TW111124828A patent/TWI835186B/zh active
-
2023
- 2023-12-27 CL CL2023003910A patent/CL2023003910A1/es unknown
-
2024
- 2024-01-31 CO CONC2024/0001078A patent/CO2024001078A2/es unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CO2024001078A2 (es) | 2024-03-07 |
| TW202308994A (zh) | 2023-03-01 |
| WO2023277658A1 (ko) | 2023-01-05 |
| AU2022302841A1 (en) | 2023-12-21 |
| CA3221122A1 (en) | 2023-01-05 |
| MX2023014804A (es) | 2024-01-12 |
| CL2023003910A1 (es) | 2024-05-31 |
| EP4349809A1 (en) | 2024-04-10 |
| EP4349809A4 (en) | 2024-10-09 |
| JP2024523604A (ja) | 2024-06-28 |
| KR20230006408A (ko) | 2023-01-10 |
| AR126353A1 (es) | 2023-10-11 |
| US20240317685A1 (en) | 2024-09-26 |
| TWI835186B (zh) | 2024-03-11 |
| CN117561237A (zh) | 2024-02-13 |
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