CL2023003910A1 - Método para preparar intermediario para síntesis de inhibidor de xantina oxidasa - Google Patents
Método para preparar intermediario para síntesis de inhibidor de xantina oxidasaInfo
- Publication number
- CL2023003910A1 CL2023003910A1 CL2023003910A CL2023003910A CL2023003910A1 CL 2023003910 A1 CL2023003910 A1 CL 2023003910A1 CL 2023003910 A CL2023003910 A CL 2023003910A CL 2023003910 A CL2023003910 A CL 2023003910A CL 2023003910 A1 CL2023003910 A1 CL 2023003910A1
- Authority
- CL
- Chile
- Prior art keywords
- synthesis
- xanthine oxidase
- oxidase inhibitor
- preparing intermediate
- preparing
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 3
- 229940123769 Xanthine oxidase inhibitor Drugs 0.000 title abstract 2
- 230000015572 biosynthetic process Effects 0.000 title abstract 2
- 238000003786 synthesis reaction Methods 0.000 title abstract 2
- 239000003064 xanthine oxidase inhibitor Substances 0.000 title abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 1
- 238000000605 extraction Methods 0.000 abstract 1
- 239000003446 ligand Substances 0.000 abstract 1
- 238000000746 purification Methods 0.000 abstract 1
- 239000007858 starting material Substances 0.000 abstract 1
- 239000000126 substance Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/08—Indoles; Hydrogenated indoles with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to carbon atoms of the hetero ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
- C07D209/42—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Indole Compounds (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
La presente invención se relaciona a un método para preparar un intermediario para síntesis de inhibidor de xantina oxidasa y, más específicamente, a un método para preparar compuestos de las fórmulas químicas 2 y 4 al utilizar materiales de partida y ligandos de bajo precio y al emplear las técnicas de extracción quelante y purificación.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| KR20210087042 | 2021-07-02 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CL2023003910A1 true CL2023003910A1 (es) | 2024-05-31 |
Family
ID=84691985
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CL2023003910A CL2023003910A1 (es) | 2021-07-02 | 2023-12-27 | Método para preparar intermediario para síntesis de inhibidor de xantina oxidasa |
Country Status (13)
| Country | Link |
|---|---|
| EP (1) | EP4349809A1 (es) |
| JP (1) | JP2024523604A (es) |
| KR (1) | KR20230006408A (es) |
| CN (1) | CN117561237A (es) |
| AR (1) | AR126353A1 (es) |
| AU (1) | AU2022302841A1 (es) |
| BR (1) | BR112023026062A2 (es) |
| CA (1) | CA3221122A1 (es) |
| CL (1) | CL2023003910A1 (es) |
| CO (1) | CO2024001078A2 (es) |
| MX (1) | MX2023014804A (es) |
| TW (1) | TWI835186B (es) |
| WO (1) | WO2023277658A1 (es) |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TW225535B (es) * | 1992-11-10 | 1994-06-21 | Hoechst Ag | |
| TWI423962B (zh) | 2009-10-07 | 2014-01-21 | Lg Life Sciences Ltd | 有效作為黃嘌呤氧化酶抑制劑之新穎化合物、其製備方法及含該化合物之醫藥組成物 |
| WO2015018356A1 (zh) * | 2013-08-08 | 2015-02-12 | 上海医药集团股份有限公司 | 二芳基乙内酰脲衍生物、其制备方法、药物组合物和应用 |
| WO2015186056A1 (en) * | 2014-06-03 | 2015-12-10 | Actelion Pharmaceuticals Ltd | Pyrazole compounds and their use as t-type calcium channel blockers |
-
2022
- 2022-07-01 JP JP2023579843A patent/JP2024523604A/ja active Pending
- 2022-07-01 WO PCT/KR2022/009544 patent/WO2023277658A1/ko active Application Filing
- 2022-07-01 AR ARP220101725A patent/AR126353A1/es unknown
- 2022-07-01 BR BR112023026062A patent/BR112023026062A2/pt unknown
- 2022-07-01 AU AU2022302841A patent/AU2022302841A1/en active Pending
- 2022-07-01 CA CA3221122A patent/CA3221122A1/en active Pending
- 2022-07-01 CN CN202280044250.8A patent/CN117561237A/zh active Pending
- 2022-07-01 MX MX2023014804A patent/MX2023014804A/es unknown
- 2022-07-01 TW TW111124828A patent/TWI835186B/zh active
- 2022-07-01 KR KR1020220081195A patent/KR20230006408A/ko not_active Application Discontinuation
- 2022-07-01 EP EP22833711.9A patent/EP4349809A1/en active Pending
-
2023
- 2023-12-27 CL CL2023003910A patent/CL2023003910A1/es unknown
-
2024
- 2024-01-31 CO CONC2024/0001078A patent/CO2024001078A2/es unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CO2024001078A2 (es) | 2024-03-07 |
| CA3221122A1 (en) | 2023-01-05 |
| TWI835186B (zh) | 2024-03-11 |
| WO2023277658A1 (ko) | 2023-01-05 |
| AR126353A1 (es) | 2023-10-11 |
| KR20230006408A (ko) | 2023-01-10 |
| BR112023026062A2 (pt) | 2024-03-05 |
| JP2024523604A (ja) | 2024-06-28 |
| MX2023014804A (es) | 2024-01-12 |
| TW202308994A (zh) | 2023-03-01 |
| AU2022302841A1 (en) | 2023-12-21 |
| EP4349809A1 (en) | 2024-04-10 |
| CN117561237A (zh) | 2024-02-13 |
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