BR112023023841A2 - Método para produzir derivado de di-hidropiridazina-3,5-diona - Google Patents
Método para produzir derivado de di-hidropiridazina-3,5-dionaInfo
- Publication number
- BR112023023841A2 BR112023023841A2 BR112023023841A BR112023023841A BR112023023841A2 BR 112023023841 A2 BR112023023841 A2 BR 112023023841A2 BR 112023023841 A BR112023023841 A BR 112023023841A BR 112023023841 A BR112023023841 A BR 112023023841A BR 112023023841 A2 BR112023023841 A2 BR 112023023841A2
- Authority
- BR
- Brazil
- Prior art keywords
- methyl
- producing
- dione derivative
- hydropyranzine
- diazaspiro
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J31/00—Catalysts comprising hydrides, coordination complexes or organic compounds
- B01J31/16—Catalysts comprising hydrides, coordination complexes or organic compounds containing coordination complexes
- B01J31/24—Phosphines, i.e. phosphorus bonded to only carbon atoms, or to both carbon and hydrogen atoms, including e.g. sp2-hybridised phosphorus compounds such as phosphabenzene, phosphole or anionic phospholide ligands
- B01J31/2404—Cyclic ligands, including e.g. non-condensed polycyclic ligands, the phosphine-P atom being a ring member or a substituent on the ring
- B01J31/2409—Cyclic ligands, including e.g. non-condensed polycyclic ligands, the phosphine-P atom being a ring member or a substituent on the ring with more than one complexing phosphine-P atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C309/00—Sulfonic acids; Halides, esters, or anhydrides thereof
- C07C309/01—Sulfonic acids
- C07C309/28—Sulfonic acids having sulfo groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
- C07C309/29—Sulfonic acids having sulfo groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton of non-condensed six-membered aromatic rings
- C07C309/30—Sulfonic acids having sulfo groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton of non-condensed six-membered aromatic rings of six-membered aromatic rings substituted by alkyl groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/26—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2231/00—Catalytic reactions performed with catalysts classified in B01J31/00
- B01J2231/40—Substitution reactions at carbon centres, e.g. C-C or C-X, i.e. carbon-hetero atom, cross-coupling, C-H activation or ring-opening reactions
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2531/00—Additional information regarding catalytic systems classified in B01J31/00
- B01J2531/001—General concepts, e.g. reviews, relating to catalyst systems and methods of making them, the concept being defined by a common material or method/theory
- B01J2531/002—Materials
- B01J2531/004—Ligands
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2531/00—Additional information regarding catalytic systems classified in B01J31/00
- B01J2531/80—Complexes comprising metals of Group VIII as the central metal
- B01J2531/82—Metals of the platinum group
- B01J2531/824—Palladium
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2531/00—Additional information regarding catalytic systems classified in B01J31/00
- B01J2531/80—Complexes comprising metals of Group VIII as the central metal
- B01J2531/84—Metals of the iron group
- B01J2531/842—Iron
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/13—Crystalline forms, e.g. polymorphs
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Diabetes (AREA)
- Urology & Nephrology (AREA)
- Materials Engineering (AREA)
- Inorganic Chemistry (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Epidemiology (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2021096200 | 2021-06-08 | ||
| PCT/JP2022/023068 WO2022260062A1 (ja) | 2021-06-08 | 2022-06-08 | ジヒドロピリダジン－３，５－ジオン誘導体の製造方法 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR112023023841A2 true BR112023023841A2 (pt) | 2024-01-30 |
Family
ID=84426032
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR112023023841A BR112023023841A2 (pt) | 2021-06-08 | 2022-06-08 | Método para produzir derivado de di-hidropiridazina-3,5-diona |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US20250115585A1 (https=) |
| EP (1) | EP4353718A4 (https=) |
| JP (1) | JP7665747B2 (https=) |
| KR (1) | KR20240019168A (https=) |
| CN (1) | CN117460727A (https=) |
| AR (1) | AR126060A1 (https=) |
| AU (1) | AU2022291310A1 (https=) |
| BR (1) | BR112023023841A2 (https=) |
| CA (1) | CA3221272A1 (https=) |
| IL (1) | IL309054A (https=) |
| MX (1) | MX2023013898A (https=) |
| TW (1) | TW202313590A (https=) |
| WO (1) | WO2022260062A1 (https=) |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2525659B1 (en) * | 2010-01-19 | 2019-02-27 | Merck Sharp & Dohme Corp. | PYRAZOLO[1,5-a]PYRIMIDINE COMPOUNDS AS mTOR INHIBITORS |
| CN102869656B (zh) | 2010-04-28 | 2014-03-12 | 安斯泰来制药株式会社 | 四氢苯并噻吩化合物 |
| EP2591354B1 (en) | 2010-07-07 | 2016-09-07 | Ardelyx, Inc. | Compounds and methods for inhibiting phosphate transport |
| KR101941048B1 (ko) | 2011-10-27 | 2019-01-22 | 아스텔라스세이야쿠 가부시키가이샤 | 아미노 알킬 치환 n-티에닐벤즈아미드 유도체 |
| WO2014003153A1 (ja) | 2012-06-28 | 2014-01-03 | 協和発酵キリン株式会社 | 置換アミド化合物 |
| PT2975030T (pt) * | 2013-03-13 | 2020-09-28 | Chugai Pharmaceutical Co Ltd | Derivado de di-hidropiridazina-3,5-diona |
| DE102013111551B3 (de) | 2013-10-21 | 2015-01-22 | Wago Verwaltungsgesellschaft Mbh | Tragschienengehäuse |
| MX383069B (es) | 2014-09-12 | 2025-03-13 | Chugai Pharmaceutical Co Ltd | Farmaceutico que contiene inhibidor de transportador de fosfato dependiente de sodio. |
| US10934280B2 (en) | 2016-08-15 | 2021-03-02 | Eli Lilly And Company | Condensed thiophene derivatives useful as NaPi-IIb inhibitors |
| CN111801335A (zh) | 2018-01-17 | 2020-10-20 | 株式会社神钢环境舒立净 | 亚硼酸酯化合物的合成方法、亚硼酸酯化合物的钠盐及其合成方法 |
-
2022
- 2022-06-02 AR ARP220101463A patent/AR126060A1/es unknown
- 2022-06-08 AU AU2022291310A patent/AU2022291310A1/en active Pending
- 2022-06-08 WO PCT/JP2022/023068 patent/WO2022260062A1/ja not_active Ceased
- 2022-06-08 TW TW111121209A patent/TW202313590A/zh unknown
- 2022-06-08 CN CN202280041402.9A patent/CN117460727A/zh active Pending
- 2022-06-08 EP EP22820241.2A patent/EP4353718A4/en active Pending
- 2022-06-08 CA CA3221272A patent/CA3221272A1/en active Pending
- 2022-06-08 JP JP2023527885A patent/JP7665747B2/ja active Active
- 2022-06-08 MX MX2023013898A patent/MX2023013898A/es unknown
- 2022-06-08 KR KR1020237045198A patent/KR20240019168A/ko active Pending
- 2022-06-08 US US18/567,432 patent/US20250115585A1/en active Pending
- 2022-06-08 IL IL309054A patent/IL309054A/en unknown
- 2022-06-08 BR BR112023023841A patent/BR112023023841A2/pt not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| EP4353718A1 (en) | 2024-04-17 |
| JP7665747B2 (ja) | 2025-04-21 |
| EP4353718A4 (en) | 2025-11-05 |
| US20250115585A1 (en) | 2025-04-10 |
| IL309054A (en) | 2024-02-01 |
| CN117460727A (zh) | 2024-01-26 |
| MX2023013898A (es) | 2023-12-11 |
| WO2022260062A1 (ja) | 2022-12-15 |
| CA3221272A1 (en) | 2022-12-15 |
| AU2022291310A1 (en) | 2024-01-18 |
| JPWO2022260062A1 (https=) | 2022-12-15 |
| KR20240019168A (ko) | 2024-02-14 |
| TW202313590A (zh) | 2023-04-01 |
| AR126060A1 (es) | 2023-09-06 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| MX2021014977A (es) | Composicion de nicotina en bolsitas y bolsita que la comprende. | |
| MX2020003458A (es) | Derivados radiomarcados de un compuesto de 2-amino-6-fluoro-n-[ 5-fluoro-piridin-3-il]-pirazolo[1,5-a]pirimidin-3- carboxamida util como inhibidor de ataxia telangiectasia mutada y rad3 relacionado (atr) cinasa, preparacion de tal compuesto y diferentes formas solidas del mismo. | |
| EA200901460A1 (ru) | Способ получения порошка металлического титана | |
| MY209048A (en) | Pyrrolotriazine derivatives for treating kit- and pdgfra-mediated diseases | |
| CY1110977T1 (el) | Υποκατεστημενα παραγωγα ινδολης για φαρμακευτικη συνθεση για θεραπεια ασθενειων του αναπνευστικου | |
| BG102873A (en) | Indole derivatives useful as endothelium receptor antagonists | |
| DE502004009142D1 (de) | Verfahren zur herstellung substituierter 3-aryl-butyl-aminverbindungen | |
| ATE493427T1 (de) | Neue mit fluor substituierte 1,4-benzothiepin-1,1-dioxidderivate, verfahren zu deren herstellung, diese verbindungen enthaltende arzneimittel und deren verwendung | |
| CY1112826T1 (el) | [4-(6-αλογονο-7-υποκατεστημενες-2,4-διοξο-1,4-διϋδρο-2η-κιναζολιν-3-υλ)-φαινυλ]-5-χλωρο-θειοφαιν-2-υλ-σουλφονυλουριες και μορφες και μεθοδοι που σχετιζονται με αυτες | |
| CY1115373T1 (el) | Παραγωγο αμινοϊνδανιου ή αλας αυτου | |
| EA200600197A1 (ru) | Получение производных соединения 1,3-дифенилпроп-2-ен-1-он | |
| NO20021875D0 (no) | Fremgangsmåte for stabilisering av benzimidazolforbindelser | |
| WO2007062999A3 (en) | 1,5-substituted indol-2-yl amide derivatives | |
| WO2020081410A3 (en) | Radioligands for imaging the lpa1 receptor | |
| SE0702522L (sv) | Sammansättningar med förlängd frisättning och metoder för deras tillverkning | |
| CY1108366T1 (el) | Βενζοσουλφονικο αλας της 7-(2-(4-(3-τριφθορομεθυλ-φαινυλ-1,2,3,6-τετραϋδρο-πυριδ-1-υλ)αιθυλ)ισοκινολινης, η παρασκευη του και η χρηση του στη φαρμακευτικη αγωγη | |
| EA200600485A1 (ru) | Способ получения производных 2-оксо-1-пирролидина | |
| CY1121986T1 (el) | Στερεη φαρμακευτικη συνθεση κυtισινης και διαδικασια για την παρασκευη της | |
| BR112023023841A2 (pt) | Método para produzir derivado de di-hidropiridazina-3,5-diona | |
| ATE518828T1 (de) | Ein-topf-verfahren zur herstellung von 3-(2,2,2- trimethylhydrazinium)propionat-dihydrat | |
| CY1108187T1 (el) | Μεθοδος για την παρασκευη παραγωγων της (3-οξο 2,3-διυδρο-1η-ισοϊνδολ-1-υλο)-ακετυλογουανιδινης | |
| WO2006052461A3 (en) | Novel formulations of eprosartan with enhanced bioavailability | |
| PL353681A1 (en) | Applications of pyrrole derivatives in production of a drug | |
| EP3845558A4 (en) | ANTIBODY HALF-MOLECULE AND METHODS FOR INHIBITION OF HOMODIMER FORMATION OF ANTIBODY HALF-MOLECULE | |
| IL287228A (en) | A process for producing modified 2-[2-(phenyl)ethylamino]alkanamide derivatives |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B11A | Dismissal acc. art.33 of ipl - examination not requested within 36 months of filing | ||
| B11N | Dismissal: publication cancelled [chapter 11.14 patent gazette] |
Free format text: ANULADA A PUBLICACAO CODIGO 11.1 NA RPI NO 2841 DE 17/06/2025 POR TER SIDO INDEVIDA. |