BR112023023260A2 - Vetor, métodos para produzir um vetor e para tratar um sujeito tendo uma doença ou uma doença infecciosa, célula hospedeira, e, composição farmacêutica - Google Patents

Vetor, métodos para produzir um vetor e para tratar um sujeito tendo uma doença ou uma doença infecciosa, célula hospedeira, e, composição farmacêutica

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Publication number
BR112023023260A2
BR112023023260A2 BR112023023260A BR112023023260A BR112023023260A2 BR 112023023260 A2 BR112023023260 A2 BR 112023023260A2 BR 112023023260 A BR112023023260 A BR 112023023260A BR 112023023260 A BR112023023260 A BR 112023023260A BR 112023023260 A2 BR112023023260 A2 BR 112023023260A2
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Brazil
Prior art keywords
vector
disease
treating
subject
producing
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BR112023023260A
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English (en)
Inventor
Brunsvik Fredriksen Agnete
Trygge Haugen Bersaas Audun
Pierre Dillard
Stine Granum
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Nykode Therapeutics ASA
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Publication of BR112023023260A2 publication Critical patent/BR112023023260A2/pt

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    • C12N15/09Recombinant DNA-technology
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    • C12N2840/00Vectors comprising a special translation-regulating system
    • C12N2840/20Vectors comprising a special translation-regulating system translation of more than one cistron
    • C12N2840/203Vectors comprising a special translation-regulating system translation of more than one cistron having an IRES

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Abstract

vetor, métodos para produzir um vetor e para tratar um sujeito tendo uma doença ou uma doença infecciosa, célula hospedeira, e, composição farmacêutica. a presente invenção refere-se aos vetores, tais como plasmídeos de dna, compreendendo sequências múltiplas de ácido nucleico engenheiradas para serem coexpressas como moléculas separadas. tais moléculas separadas incluem um primeiro polipeptídeo, em que o primeiro polipeptídeo compreende uma unidade de alvejamento que alveja células que apresentam antígeno, uma unidade de multimerização, tal como unidade de dimerização e uma unidade antigênica compreendendo um ou mais antígenos ou partes dos mesmos e um ou mais compostos imunoestimulatórios.
BR112023023260A 2021-05-10 2022-05-10 Vetor, métodos para produzir um vetor e para tratar um sujeito tendo uma doença ou uma doença infecciosa, célula hospedeira, e, composição farmacêutica BR112023023260A2 (pt)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
DKPA202170221 2021-05-10
DKPA202170364 2021-07-08
DKPA202270113 2022-03-18
DKPA202270186 2022-04-07
PCT/EP2022/062665 WO2022238420A2 (en) 2021-05-10 2022-05-10 Co-expression of constructs and immunostimulatory compounds

Publications (1)

Publication Number Publication Date
BR112023023260A2 true BR112023023260A2 (pt) 2024-01-30

Family

ID=82016537

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BR112023023260A BR112023023260A2 (pt) 2021-05-10 2022-05-10 Vetor, métodos para produzir um vetor e para tratar um sujeito tendo uma doença ou uma doença infecciosa, célula hospedeira, e, composição farmacêutica

Country Status (8)

Country Link
EP (1) EP4337248A2 (pt)
JP (1) JP2024516882A (pt)
KR (1) KR20240019135A (pt)
AU (1) AU2022274154A1 (pt)
BR (1) BR112023023260A2 (pt)
CA (1) CA3216720A1 (pt)
IL (1) IL308310A (pt)
WO (1) WO2022238420A2 (pt)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2024092025A1 (en) 2022-10-25 2024-05-02 Nykode Therapeutics ASA Constructs and their use

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8932603B2 (en) 2003-02-25 2015-01-13 Vaccibody As Modified antibody
WO2011161244A1 (en) 2010-06-25 2011-12-29 Vaccibody As Homodimeric protein constructs
AU2012356969B2 (en) 2011-12-21 2017-05-04 Nykode Therapeutics ASA Vaccines against HPV
EP3362103A4 (en) * 2015-10-12 2020-02-05 Nantomics, LLC COMPOSITIONS AND METHODS USING VIRAL CANCER NEOEPITOPES
KR20180100659A (ko) 2016-01-08 2018-09-11 백시바디 에이에스 치료적 항암 네오에피토프 백신
BR112021005702A8 (pt) 2018-09-27 2022-11-08 Vaccibody As Método para selecionar neoepítopos
CN113631185A (zh) 2019-02-27 2021-11-09 尼克塔治疗公司 用于治疗癌症的免疫治疗组合
WO2020221783A1 (en) 2019-04-29 2020-11-05 Vaccibody As Methods for pre-selection of neoepitopes
KR20230004585A (ko) 2020-04-09 2023-01-06 니코데 테라퓨틱스 에이에스에이 개별화된 치료용 항암 백신
JP2023524054A (ja) 2020-05-01 2023-06-08 ナイコード セラピューティクス アルメン アクスイェ セルスカプ ベータコロナウイルスの予防と治療
EP4181949A1 (en) 2020-07-14 2023-05-24 Evaxion Biotech A/S Apc targeting units for immunotherapy

Also Published As

Publication number Publication date
EP4337248A2 (en) 2024-03-20
IL308310A (en) 2024-01-01
AU2022274154A1 (en) 2023-11-16
CA3216720A1 (en) 2022-11-17
KR20240019135A (ko) 2024-02-14
WO2022238420A3 (en) 2022-12-22
WO2022238420A2 (en) 2022-11-17
JP2024516882A (ja) 2024-04-17

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