BR112023014818A2 - Uso de ésteres de cetona exógena para induzir perda de peso em mamíferos - Google Patents
Uso de ésteres de cetona exógena para induzir perda de peso em mamíferosInfo
- Publication number
- BR112023014818A2 BR112023014818A2 BR112023014818A BR112023014818A BR112023014818A2 BR 112023014818 A2 BR112023014818 A2 BR 112023014818A2 BR 112023014818 A BR112023014818 A BR 112023014818A BR 112023014818 A BR112023014818 A BR 112023014818A BR 112023014818 A2 BR112023014818 A2 BR 112023014818A2
- Authority
- BR
- Brazil
- Prior art keywords
- weight loss
- mammals
- induce weight
- ketone esters
- exogenous ketone
- Prior art date
Links
- 241000124008 Mammalia Species 0.000 title abstract 4
- 230000004580 weight loss Effects 0.000 title abstract 3
- 150000002576 ketones Chemical class 0.000 title 1
- CDQSJQSWAWPGKG-UHFFFAOYSA-N butane-1,1-diol Chemical class CCCC(O)O CDQSJQSWAWPGKG-UHFFFAOYSA-N 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 235000014113 dietary fatty acids Nutrition 0.000 abstract 1
- 229930195729 fatty acid Natural products 0.000 abstract 1
- 239000000194 fatty acid Substances 0.000 abstract 1
- 150000004665 fatty acids Chemical class 0.000 abstract 1
- 230000001939 inductive effect Effects 0.000 abstract 1
- -1 ketone esters Chemical class 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
- A61K31/225—Polycarboxylic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/12—Ketones
- A61K31/121—Ketones acyclic
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/12—Carboxylic acids; Salts or anhydrides thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/46—Ingredients of undetermined constitution or reaction products thereof, e.g. skin, bone, milk, cotton fibre, eggshell, oxgall or plant extracts
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Emergency Medicine (AREA)
- Child & Adolescent Psychology (AREA)
- Diabetes (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Botany (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
- Medicinal Preparation (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
uso de ésteres de cetona exógena para induzir perda de peso em mamíferos . em várias modalidades, método e composições são providos para induzir perda de peso em um mamífero. em certas modalidades, os métodos envolvem a administração a um mamífero de uma quantidade eficaz de compostos ß-hidroxiéster de ácido graxo e/ou um ou mais ésteres de butanodiol.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202163141754P | 2021-01-26 | 2021-01-26 | |
| PCT/US2022/013533 WO2022164755A1 (en) | 2021-01-26 | 2022-01-24 | Use of exogenous ketone esters to induce weight loss in mammals |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR112023014818A2 true BR112023014818A2 (pt) | 2023-10-03 |
Family
ID=82653822
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR112023014818A BR112023014818A2 (pt) | 2021-01-26 | 2022-01-24 | Uso de ésteres de cetona exógena para induzir perda de peso em mamíferos |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US20240122890A1 (pt) |
| EP (1) | EP4284358A1 (pt) |
| JP (1) | JP2024504424A (pt) |
| KR (1) | KR20230136627A (pt) |
| AU (1) | AU2022212793A1 (pt) |
| BR (1) | BR112023014818A2 (pt) |
| CA (1) | CA3206310A1 (pt) |
| IL (1) | IL304762A (pt) |
| MX (1) | MX2023008675A (pt) |
| WO (1) | WO2022164755A1 (pt) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2023212091A1 (en) * | 2022-04-29 | 2023-11-02 | Buck Institute For Research On Aging | Novel ketone ester compounds |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR102638807B1 (ko) * | 2016-06-07 | 2024-02-21 | 더 제이. 데이비드 글래드스톤 인스티튜트, 어 테스터멘터리 트러스트 이스타빌리쉬드 언더 더 윌 오브 제이. 데이비드 글래드스톤 | 베타-히드록시부티레이트 및 부탄디올의 중쇄 지방산 에스테르 및 이것을 사용하는 조성물 및 이것을 사용하는 방법 |
| WO2019147503A1 (en) * | 2018-01-25 | 2019-08-01 | Buck Institute For Research On Aging | Synthesis of 3-hydroxybutyryl 3-hydroxybutyrate and related compounds |
-
2022
- 2022-01-24 CA CA3206310A patent/CA3206310A1/en active Pending
- 2022-01-24 EP EP22746444.3A patent/EP4284358A1/en not_active Withdrawn
- 2022-01-24 WO PCT/US2022/013533 patent/WO2022164755A1/en active Application Filing
- 2022-01-24 JP JP2023544699A patent/JP2024504424A/ja active Pending
- 2022-01-24 AU AU2022212793A patent/AU2022212793A1/en active Pending
- 2022-01-24 BR BR112023014818A patent/BR112023014818A2/pt unknown
- 2022-01-24 US US18/261,986 patent/US20240122890A1/en active Pending
- 2022-01-24 KR KR1020237028287A patent/KR20230136627A/ko unknown
- 2022-01-24 MX MX2023008675A patent/MX2023008675A/es unknown
-
2023
- 2023-07-26 IL IL304762A patent/IL304762A/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CA3206310A1 (en) | 2022-08-04 |
| JP2024504424A (ja) | 2024-01-31 |
| WO2022164755A1 (en) | 2022-08-04 |
| EP4284358A1 (en) | 2023-12-06 |
| IL304762A (en) | 2023-09-01 |
| MX2023008675A (es) | 2023-08-02 |
| AU2022212793A9 (en) | 2024-09-19 |
| US20240122890A1 (en) | 2024-04-18 |
| KR20230136627A (ko) | 2023-09-26 |
| AU2022212793A1 (en) | 2023-08-10 |
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