BR112022026700A2 - Polipeptídeos de ligação de receptor de il23 humano - Google Patents

Polipeptídeos de ligação de receptor de il23 humano

Info

Publication number
BR112022026700A2
BR112022026700A2 BR112022026700A BR112022026700A BR112022026700A2 BR 112022026700 A2 BR112022026700 A2 BR 112022026700A2 BR 112022026700 A BR112022026700 A BR 112022026700A BR 112022026700 A BR112022026700 A BR 112022026700A BR 112022026700 A2 BR112022026700 A2 BR 112022026700A2
Authority
BR
Brazil
Prior art keywords
human
receptor binding
binding polypeptides
polypeptides
hil
Prior art date
Application number
BR112022026700A
Other languages
English (en)
Inventor
Berger Stephanie
Seeger Franziska
Baker David
Yu Ta-Yi
Original Assignee
Univ Washington
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Washington filed Critical Univ Washington
Publication of BR112022026700A2 publication Critical patent/BR112022026700A2/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/001—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof by chemical synthesis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/54—Interleukins [IL]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/715—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons
    • C07K14/7155—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons for interleukins [IL]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Toxicology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Immunology (AREA)
  • Cell Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Wood Science & Technology (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Epidemiology (AREA)
  • Plant Pathology (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicinal Preparation (AREA)

Abstract

POLIPEPTÍDEOS DE LIGAÇÃO DE RECEPTOR DE IL23 HUMANO. A presente descrição provê polipeptídeos que se ligam ao IL-23R humano (hIL-23R), proteínas que se ligam ao hIL-23R condicionalmente ativas de modo máximo, multímeros das mesmas e métodos para usar os polipeptídeos e proteínas de ligação para o uso terapêutico.
BR112022026700A 2020-06-29 2021-06-25 Polipeptídeos de ligação de receptor de il23 humano BR112022026700A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US202063045381P 2020-06-29 2020-06-29
PCT/US2021/039122 WO2022005899A1 (en) 2020-06-29 2021-06-25 Human il23 receptor binding polypeptides

Publications (1)

Publication Number Publication Date
BR112022026700A2 true BR112022026700A2 (pt) 2023-01-24

Family

ID=76959124

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112022026700A BR112022026700A2 (pt) 2020-06-29 2021-06-25 Polipeptídeos de ligação de receptor de il23 humano

Country Status (11)

Country Link
US (1) US20230357323A1 (pt)
EP (1) EP4172183A1 (pt)
JP (1) JP2023531771A (pt)
KR (1) KR20230030649A (pt)
CN (1) CN115916810A (pt)
AU (1) AU2021301192A1 (pt)
BR (1) BR112022026700A2 (pt)
CA (1) CA3183027A1 (pt)
IL (1) IL299529A (pt)
MX (1) MX2022016012A (pt)
WO (1) WO2022005899A1 (pt)

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2777162A1 (en) * 2009-10-09 2011-04-14 Anaphore, Inc. Polypeptides that bind il-23r
KR102482790B1 (ko) * 2014-07-17 2022-12-29 프로타고니스트 테라퓨틱스, 인코포레이티드 인터루킨-23 수용체의 경구용 펩티드 억제제 및 염증성 장 질환을 치료하기 위한 그의 용도

Also Published As

Publication number Publication date
CA3183027A1 (en) 2022-01-06
KR20230030649A (ko) 2023-03-06
IL299529A (en) 2023-02-01
JP2023531771A (ja) 2023-07-25
US20230357323A1 (en) 2023-11-09
MX2022016012A (es) 2023-03-10
CN115916810A (zh) 2023-04-04
EP4172183A1 (en) 2023-05-03
AU2021301192A1 (en) 2023-02-02
WO2022005899A1 (en) 2022-01-06

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