BR112022024098A2 - Formulações e métodos para tratar a disfunção erétil - Google Patents
Formulações e métodos para tratar a disfunção erétilInfo
- Publication number
- BR112022024098A2 BR112022024098A2 BR112022024098A BR112022024098A BR112022024098A2 BR 112022024098 A2 BR112022024098 A2 BR 112022024098A2 BR 112022024098 A BR112022024098 A BR 112022024098A BR 112022024098 A BR112022024098 A BR 112022024098A BR 112022024098 A2 BR112022024098 A2 BR 112022024098A2
- Authority
- BR
- Brazil
- Prior art keywords
- vardenafil
- formulation
- formulations
- methods
- erectile dysfunction
- Prior art date
Links
- 239000000203 mixture Substances 0.000 title abstract 6
- 208000010228 Erectile Dysfunction Diseases 0.000 title abstract 2
- 201000001881 impotence Diseases 0.000 title abstract 2
- 238000000034 method Methods 0.000 title abstract 2
- SECKRCOLJRRGGV-UHFFFAOYSA-N Vardenafil Chemical compound CCCC1=NC(C)=C(C(N=2)=O)N1NC=2C(C(=CC=1)OCC)=CC=1S(=O)(=O)N1CCN(CC)CC1 SECKRCOLJRRGGV-UHFFFAOYSA-N 0.000 abstract 4
- 238000009472 formulation Methods 0.000 abstract 4
- 229960002381 vardenafil Drugs 0.000 abstract 4
- 125000005456 glyceride group Chemical group 0.000 abstract 2
- 239000003960 organic solvent Substances 0.000 abstract 2
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 abstract 1
- 239000004721 Polyphenylene oxide Substances 0.000 abstract 1
- XXJWXESWEXIICW-UHFFFAOYSA-N diethylene glycol monoethyl ether Chemical compound CCOCCOCCO XXJWXESWEXIICW-UHFFFAOYSA-N 0.000 abstract 1
- 229940075557 diethylene glycol monoethyl ether Drugs 0.000 abstract 1
- 230000004064 dysfunction Effects 0.000 abstract 1
- 230000002708 enhancing effect Effects 0.000 abstract 1
- 210000004400 mucous membrane Anatomy 0.000 abstract 1
- 229920000570 polyether Polymers 0.000 abstract 1
- 229920006395 saturated elastomer Polymers 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/53—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with three nitrogens as the only ring hetero atoms, e.g. chlorazanil, melamine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/4985—Pyrazines or piperazines ortho- or peri-condensed with heterocyclic ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0043—Nose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
- A61K9/006—Oral mucosa, e.g. mucoadhesive forms, sublingual droplets; Buccal patches or films; Buccal sprays
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/2031—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyethylene oxide, poloxamers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nutrition Science (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Physiology (AREA)
- Otolaryngology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Gynecology & Obstetrics (AREA)
- Endocrinology (AREA)
- Reproductive Health (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202063029881P | 2020-05-26 | 2020-05-26 | |
| PCT/US2021/034334 WO2021242913A1 (en) | 2020-05-26 | 2021-05-26 | Formulations and methods for treating erectile dysfunction |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR112022024098A2 true BR112022024098A2 (pt) | 2023-02-07 |
Family
ID=78722740
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR112022024098A BR112022024098A2 (pt) | 2020-05-26 | 2021-05-26 | Formulações e métodos para tratar a disfunção erétil |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US20240216383A1 (https=) |
| EP (1) | EP4157449A4 (https=) |
| JP (1) | JP2024521765A (https=) |
| KR (1) | KR20240013128A (https=) |
| CN (1) | CN116568289A (https=) |
| AU (1) | AU2021280285A1 (https=) |
| BR (1) | BR112022024098A2 (https=) |
| CA (1) | CA3179630A1 (https=) |
| IL (1) | IL298432A (https=) |
| WO (2) | WO2021242913A1 (https=) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PL247528B1 (pl) * | 2023-04-08 | 2025-07-21 | Sativa Med Spolka Akcyjna | Płynna kompozycja inhibitorów fosfodiesterazy typu 5 (PDE-5), sposób jej wytwarzania oraz jej zastosowanie do leczenia zaburzeń erekcji |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1237538A2 (en) * | 1999-11-18 | 2002-09-11 | Natco Pharma Limited | An improved pharmaceutical composition for treating male erectile dysfunction |
| DE10118306A1 (de) * | 2001-04-12 | 2002-10-17 | Bayer Ag | Imidazotriazinonhaltige Zusammensetzungen zur nasalen Applikation |
| DE102004023069A1 (de) * | 2004-05-11 | 2005-12-08 | Bayer Healthcare Ag | Neue Darreichungsformen des PDE 5-Inhibitors Vardenafil |
| US20060051413A1 (en) * | 2004-09-08 | 2006-03-09 | Chow Sing S M | Method of enhancing absorptions of transmucosal administration formulations |
| DE102005009241A1 (de) * | 2005-03-01 | 2006-09-07 | Bayer Healthcare Ag | Arzneiformen mit kontrollierter Bioverfügbarkeit |
| DE102005009240A1 (de) * | 2005-03-01 | 2006-09-07 | Bayer Healthcare Ag | Arzneiformen mit verbesserten pharmakokinetischen Eigenschaften |
| US20060207596A1 (en) * | 2005-03-18 | 2006-09-21 | Fairfield Clinical Trials, Llc | Device and method for delivery of combination nasal medication |
| US8911751B2 (en) * | 2005-10-11 | 2014-12-16 | Yissum Research Development Company Of The Hebrew University Of Jerusalem | Compositions for nasal delivery |
| WO2009052421A1 (en) * | 2007-10-19 | 2009-04-23 | Innozen, Inc. | Composition for administering an active ingredient and method for making and using the same |
| GB2497933B (en) * | 2011-12-21 | 2014-12-24 | Londonpharma Ltd | Drug delivery technology |
| US20140271847A1 (en) * | 2013-03-13 | 2014-09-18 | SatisPharma, LLC | Formulations and methods for rapid penile erections |
| US20170014417A1 (en) * | 2015-07-14 | 2017-01-19 | Lipp Life Sciences Llc | Pharmaceutical administration system for the transdermal application of vardenafil |
| MX2020005890A (es) * | 2017-12-20 | 2020-10-19 | Klaria Pharma Holding Ab | Formulacion de pelicula que comprende vardenafil, metodo para su preparacion y uso de la misma. |
| JP7365409B2 (ja) * | 2018-06-28 | 2023-10-19 | エイアールエックス エルエルシー | 溶解性単位用量膜構造物を製造するための分配方法 |
-
2021
- 2021-05-26 BR BR112022024098A patent/BR112022024098A2/pt unknown
- 2021-05-26 WO PCT/US2021/034334 patent/WO2021242913A1/en not_active Ceased
- 2021-05-26 AU AU2021280285A patent/AU2021280285A1/en active Pending
- 2021-05-26 CA CA3179630A patent/CA3179630A1/en active Pending
- 2021-05-26 EP EP21811862.8A patent/EP4157449A4/en active Pending
- 2021-05-26 IL IL298432A patent/IL298432A/en unknown
- 2021-12-01 US US17/999,826 patent/US20240216383A1/en active Pending
- 2021-12-01 WO PCT/US2021/061488 patent/WO2022250731A1/en not_active Ceased
- 2021-12-01 CN CN202180076999.6A patent/CN116568289A/zh active Pending
- 2021-12-01 JP JP2023572709A patent/JP2024521765A/ja active Pending
- 2021-12-01 KR KR1020237040722A patent/KR20240013128A/ko active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| JP2024521765A (ja) | 2024-06-04 |
| EP4157449A4 (en) | 2024-05-29 |
| CN116568289A (zh) | 2023-08-08 |
| EP4157449A1 (en) | 2023-04-05 |
| KR20240013128A (ko) | 2024-01-30 |
| CA3179630A1 (en) | 2021-12-02 |
| WO2021242913A1 (en) | 2021-12-02 |
| AU2021280285A1 (en) | 2023-02-02 |
| US20240216383A1 (en) | 2024-07-04 |
| IL298432A (en) | 2023-01-01 |
| WO2022250731A1 (en) | 2022-12-01 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B25G | Requested change of headquarter approved |
Owner name: STRATEGIC DRUG SOLUTIONS, INC. (US) |