BR112022023227A2 - Composição de revestimento, método de preparação de um revestimento hidrofílico em um substrato e dispositivo médico compreendendo tal revestimento - Google Patents

Composição de revestimento, método de preparação de um revestimento hidrofílico em um substrato e dispositivo médico compreendendo tal revestimento

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Publication number
BR112022023227A2
BR112022023227A2 BR112022023227A BR112022023227A BR112022023227A2 BR 112022023227 A2 BR112022023227 A2 BR 112022023227A2 BR 112022023227 A BR112022023227 A BR 112022023227A BR 112022023227 A BR112022023227 A BR 112022023227A BR 112022023227 A2 BR112022023227 A2 BR 112022023227A2
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BR
Brazil
Prior art keywords
coating
hydrophilic
substrate
medical device
composition
Prior art date
Application number
BR112022023227A
Other languages
English (en)
Inventor
Wilhelmus Belt Johannes
Original Assignee
Dsm Ip Assets Bv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dsm Ip Assets Bv filed Critical Dsm Ip Assets Bv
Publication of BR112022023227A2 publication Critical patent/BR112022023227A2/pt

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    • C09D4/00Coating compositions, e.g. paints, varnishes or lacquers, based on organic non-macromolecular compounds having at least one polymerisable carbon-to-carbon unsaturated bond ; Coating compositions, based on monomers of macromolecular compounds of groups C09D183/00 - C09D183/16
    • C09D4/06Organic non-macromolecular compounds having at least one polymerisable carbon-to-carbon unsaturated bond in combination with a macromolecular compound other than an unsaturated polymer of groups C09D159/00 - C09D187/00
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    • C10M169/00Lubricating compositions characterised by containing as components a mixture of at least two types of ingredient selected from base-materials, thickeners or additives, covered by the preceding groups, each of these compounds being essential
    • C10M169/04Mixtures of base-materials and additives
    • C10M169/044Mixtures of base-materials and additives the additives being a mixture of non-macromolecular and macromolecular compounds
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    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L29/00Materials for catheters, medical tubing, cannulae, or endoscopes or for coating catheters
    • A61L29/08Materials for coatings
    • A61L29/085Macromolecular materials
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L29/00Materials for catheters, medical tubing, cannulae, or endoscopes or for coating catheters
    • A61L29/14Materials characterised by their function or physical properties, e.g. lubricating compositions
    • A61L29/145Hydrogels or hydrocolloids
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    • C08F2/00Processes of polymerisation
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    • C10N2050/023Multi-layer lubricant coatings
    • CCHEMISTRY; METALLURGY
    • C10PETROLEUM, GAS OR COKE INDUSTRIES; TECHNICAL GASES CONTAINING CARBON MONOXIDE; FUELS; LUBRICANTS; PEAT
    • C10NINDEXING SCHEME ASSOCIATED WITH SUBCLASS C10M RELATING TO LUBRICATING COMPOSITIONS
    • C10N2070/00Specific manufacturing methods for lubricant compositions

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Polymers & Plastics (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Materials Engineering (AREA)
  • Wood Science & Technology (AREA)
  • Veterinary Medicine (AREA)
  • Dispersion Chemistry (AREA)
  • Paints Or Removers (AREA)
  • Materials For Medical Uses (AREA)
  • Macromonomer-Based Addition Polymer (AREA)
  • Polymerisation Methods In General (AREA)
  • Graft Or Block Polymers (AREA)

Abstract

COMPOSIÇÃO DE REVESTIMENTO, MÉTODO DE PREPARAÇÃO DE UM REVESTIMENTO HIDROFÍLICO EM UM SUBSTRATO E DISPOSITIVO MÉDICO COMPREENDENDO TAL REVESTIMENTO. A revelação refere-se a uma composição de revestimento compreendendo um composto polimerizável de fórmula [1], em que G é um resíduo de um oligômero hidroxi funcional hidrofóbico, n é 1-10, cada R1 independentemente é um resíduo de um composto de C6-C20 hidrocarboneto alifático, cicloalifático ou aromático, e Z é uma porção tendo um grupo polimerizável; um polímero hidrofílico; um fotoiniciador; opcionalmente um ou mais compostos adicionais, e um solvente. O composto polimerizável de fórmula [1] está normalmente presente em uma quantidade de 2,0-30% em massa com base na massa seca total da composição. Tal composição de revestimento pode ser preparada em um revestimento hidrofílico de camada única com boa aderência sobre uma superfície de substratos polímeros sem prover uma camada de preparo ou modificar quimicamente a superfície do substrato. Quando da umectação, o revestimento apresenta uma excelente lubricidade e durabilidade. Em aspectos adicionais, a revelação provê um método de aplicação de um revestimento hidrofílico e, opcionalmente, lúbrico sobre um artigo; e um artigo semelhante a um dispositivo médico tendo, sobre pelo menos parte de sua superfície, um revestimento de camada única, hidrofílico e, opcionalmente, lúbrico, como um cateter, fio guia ou um dispositivo de entrega para implante.
BR112022023227A 2020-05-18 2021-05-11 Composição de revestimento, método de preparação de um revestimento hidrofílico em um substrato e dispositivo médico compreendendo tal revestimento BR112022023227A2 (pt)

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PCT/EP2021/062541 WO2021233743A1 (en) 2020-05-18 2021-05-11 Coating composition, method of making a hydrophilic coating on a substrate, and medical device comprising such coating

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US8871869B2 (en) 2005-12-09 2014-10-28 Dsm Ip Assets B.V. Hydrophilic coating
WO2008031595A2 (en) 2006-09-13 2008-03-20 Dsm Ip Assets B.V. Coated medical device
US20090041923A1 (en) 2007-08-06 2009-02-12 Abbott Cardiovascular Systems Inc. Medical device having a lubricious coating with a hydrophilic compound in an interlocking network
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