BR112022017136A2 - Conjugação mediada por transglutaminase - Google Patents
Conjugação mediada por transglutaminaseInfo
- Publication number
- BR112022017136A2 BR112022017136A2 BR112022017136A BR112022017136A BR112022017136A2 BR 112022017136 A2 BR112022017136 A2 BR 112022017136A2 BR 112022017136 A BR112022017136 A BR 112022017136A BR 112022017136 A BR112022017136 A BR 112022017136A BR 112022017136 A2 BR112022017136 A2 BR 112022017136A2
- Authority
- BR
- Brazil
- Prior art keywords
- transglutaminase
- conjugation mediated
- conjugation
- mediated
- methods
- Prior art date
Links
- 108060008539 Transglutaminase Proteins 0.000 title abstract 2
- 230000021615 conjugation Effects 0.000 title abstract 2
- 230000001404 mediated effect Effects 0.000 title abstract 2
- 102000003601 transglutaminase Human genes 0.000 title abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
Classifications
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- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/117—Nucleic acids having immunomodulatory properties, e.g. containing CpG-motifs
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Abstract
CONJUGAÇÃO MEDIADA POR TRANSGLUTAMINASE. A presente invenção refere-se a conjugados anticorpo-oligonucleotídeo, métodos de preparação dos mesmos e métodos de uso dos mesmos. Também são fornecidos compostos, composições e kits relacionados.
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PCT/US2021/020039 WO2021174091A1 (en) | 2020-02-28 | 2021-02-26 | Transglutaminase-mediated conjugation |
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-
2021
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- 2021-02-26 WO PCT/US2021/020039 patent/WO2021174091A1/en unknown
- 2021-02-26 CN CN202180029271.8A patent/CN115427458A/zh active Pending
- 2021-02-26 TW TW110107136A patent/TW202146056A/zh unknown
- 2021-02-26 BR BR112022017136A patent/BR112022017136A2/pt unknown
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- 2021-02-26 KR KR1020227033683A patent/KR20220162130A/ko unknown
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KR20220162130A (ko) | 2022-12-07 |
US11795463B2 (en) | 2023-10-24 |
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US11920136B2 (en) | 2024-03-05 |
TW202146056A (zh) | 2021-12-16 |
CA3169523A1 (en) | 2021-09-02 |
MX2022010515A (es) | 2022-11-14 |
AU2021226023A1 (en) | 2022-09-15 |
JP2023515566A (ja) | 2023-04-13 |
US20230130194A1 (en) | 2023-04-27 |
US20220380768A1 (en) | 2022-12-01 |
CN115427458A (zh) | 2022-12-02 |
WO2021174091A1 (en) | 2021-09-02 |
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