BR112022011096A2 - Dispositivos inaladores, formulações de medicamentos usados com os mesmos e métodos de fabricação - Google Patents

Dispositivos inaladores, formulações de medicamentos usados com os mesmos e métodos de fabricação

Info

Publication number
BR112022011096A2
BR112022011096A2 BR112022011096A BR112022011096A BR112022011096A2 BR 112022011096 A2 BR112022011096 A2 BR 112022011096A2 BR 112022011096 A BR112022011096 A BR 112022011096A BR 112022011096 A BR112022011096 A BR 112022011096A BR 112022011096 A2 BR112022011096 A2 BR 112022011096A2
Authority
BR
Brazil
Prior art keywords
recess
manufacturing methods
air
inhaler devices
drug
Prior art date
Application number
BR112022011096A
Other languages
English (en)
Inventor
Eliahu Avi
Abercrombie Stuart
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of BR112022011096A2 publication Critical patent/BR112022011096A2/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0028—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
    • A61M15/003—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using capsules, e.g. to be perforated or broken-up
    • A61M15/0033—Details of the piercing or cutting means
    • A61M15/0035—Piercing means
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M11/00—Sprayers or atomisers specially adapted for therapeutic purposes
    • A61M11/001—Particle size control
    • A61M11/002—Particle size control by flow deviation causing inertial separation of transported particles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M11/00—Sprayers or atomisers specially adapted for therapeutic purposes
    • A61M11/001—Particle size control
    • A61M11/003—Particle size control by passing the aerosol trough sieves or filters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0001—Details of inhalators; Constructional features thereof
    • A61M15/0005—Details of inhalators; Constructional features thereof with means for agitating the medicament
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0001—Details of inhalators; Constructional features thereof
    • A61M15/0005—Details of inhalators; Constructional features thereof with means for agitating the medicament
    • A61M15/0006—Details of inhalators; Constructional features thereof with means for agitating the medicament using rotating means
    • A61M15/0008—Details of inhalators; Constructional features thereof with means for agitating the medicament using rotating means rotating by airflow
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0001—Details of inhalators; Constructional features thereof
    • A61M15/0021—Mouthpieces therefor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0028—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0028—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
    • A61M15/003—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using capsules, e.g. to be perforated or broken-up
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0028—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
    • A61M15/003—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using capsules, e.g. to be perforated or broken-up
    • A61M15/0033—Details of the piercing or cutting means
    • A61M15/0041—Details of the piercing or cutting means with movable piercing or cutting means
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0086—Inhalation chambers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2202/00—Special media to be introduced, removed or treated
    • A61M2202/06—Solids
    • A61M2202/064—Powder
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2206/00—Characteristics of a physical parameter; associated device therefor
    • A61M2206/10—Flow characteristics
    • A61M2206/14—Static flow deviators in tubes disturbing laminar flow in tubes, e.g. archimedes screws
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2210/00—Anatomical parts of the body
    • A61M2210/10—Trunk
    • A61M2210/1025—Respiratory system
    • A61M2210/1039—Lungs

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Pulmonology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical & Material Sciences (AREA)
  • Dispersion Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

DISPOSITIVOS INALADORES,FORMULAÇÕES DE MEDICAMENTOS USADOS COM OS MESMOS E MÉTODOS DE FABRICAÇÃO. A presente invenção refere-se a dispositivos inaladores de pó seco exemplares, que podem incluir um corpo de alojamento com um recesso de cápsula de medicamento no mesmo, um par de entradas de ar cada uma conectando-se fluidamente ao recesso e um corpo de saída acoplado ao corpo de alojamento. Cada entrada pode ter uma largura não superior a 1,17 mm. O corpo de saída pode ter um canal conectando fluidamente o recesso a uma abertura e configurado para permitir que um usuário puxe ar através da abertura, permitindo assim que uma corrente de ar seja puxada através das entradas de ar para o recesso do corpo do alojamento onde faz com que a cápsula gire e ejete seu conteúdo na corrente de ar e através do canal do corpo de saída e abertura para entregue a substância nos pulmões do usuário. Também são fornecidas formulações de misturas de fármacos respiráveis em pó seco, métodos de fabricação das formulações e combinações de fármacos/dispositivos.
BR112022011096A 2019-12-09 2020-12-09 Dispositivos inaladores, formulações de medicamentos usados com os mesmos e métodos de fabricação BR112022011096A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201962945748P 2019-12-09 2019-12-09
PCT/US2020/063889 WO2021119055A1 (en) 2019-12-09 2020-12-09 Inhaler devices, medication formulations used therewith and methods of manufacture

Publications (1)

Publication Number Publication Date
BR112022011096A2 true BR112022011096A2 (pt) 2022-08-23

Family

ID=74068691

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112022011096A BR112022011096A2 (pt) 2019-12-09 2020-12-09 Dispositivos inaladores, formulações de medicamentos usados com os mesmos e métodos de fabricação

Country Status (12)

Country Link
US (1) US20220409831A1 (pt)
EP (1) EP4072634A1 (pt)
JP (2) JP2023504576A (pt)
KR (1) KR20220103741A (pt)
CN (1) CN114945398A (pt)
AU (2) AU2020402019A1 (pt)
BR (1) BR112022011096A2 (pt)
CA (1) CA3159735A1 (pt)
IL (1) IL293505A (pt)
MX (1) MX2022006959A (pt)
TW (1) TW202135880A (pt)
WO (1) WO2021119055A1 (pt)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2024095105A1 (de) * 2022-11-04 2024-05-10 Skietta Ag Vaporizer zur verdampfung eines inhalationsmediums

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ITMI20010357U1 (it) 2001-06-28 2002-12-30 Plastiape Spa Dispositivo inalatore
US20030235538A1 (en) * 2002-04-09 2003-12-25 Boehringer Ingelheim Pharma Gmbh & Co. Kg Method for the administration of an anticholinergic by inhalation
GB0410712D0 (en) 2004-05-13 2004-06-16 Novartis Ag Organic compounds
ITMO20110051A1 (it) * 2011-03-04 2012-09-05 Ano & C Inalatore portatile di sostanze in polvere
KR101466616B1 (ko) * 2012-10-11 2014-11-28 한미약품 주식회사 건조분말 흡입장치
ES2936415T3 (es) * 2017-04-17 2023-03-16 Respira Therapeutics Inc Inhalador de dosis unitaria de polvo seco

Also Published As

Publication number Publication date
IL293505A (en) 2022-08-01
WO2021119055A1 (en) 2021-06-17
AU2020402019A1 (en) 2022-06-02
WO2021119055A8 (en) 2022-06-09
TW202135880A (zh) 2021-10-01
KR20220103741A (ko) 2022-07-22
MX2022006959A (es) 2022-07-12
JP2023504576A (ja) 2023-02-03
AU2024202069A1 (en) 2024-04-18
US20220409831A1 (en) 2022-12-29
CN114945398A (zh) 2022-08-26
JP2023179756A (ja) 2023-12-19
CA3159735A1 (en) 2021-06-17
EP4072634A1 (en) 2022-10-19

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