BR112022010900A2 - Composições de curcumina para osteoartrite e bem-estar da articulação - Google Patents
Composições de curcumina para osteoartrite e bem-estar da articulaçãoInfo
- Publication number
- BR112022010900A2 BR112022010900A2 BR112022010900A BR112022010900A BR112022010900A2 BR 112022010900 A2 BR112022010900 A2 BR 112022010900A2 BR 112022010900 A BR112022010900 A BR 112022010900A BR 112022010900 A BR112022010900 A BR 112022010900A BR 112022010900 A2 BR112022010900 A2 BR 112022010900A2
- Authority
- BR
- Brazil
- Prior art keywords
- curcumin
- osteoarthritis
- composition
- stable
- compositions
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/12—Ketones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/906—Zingiberaceae (Ginger family)
- A61K36/9066—Curcuma, e.g. common turmeric, East Indian arrowroot or mango ginger
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/12—Carboxylic acids; Salts or anhydrides thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/20—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing sulfur, e.g. dimethyl sulfoxide [DMSO], docusate, sodium lauryl sulfate or aminosulfonic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/22—Heterocyclic compounds, e.g. ascorbic acid, tocopherol or pyrrolidones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/24—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing atoms other than carbon, hydrogen, oxygen, halogen, nitrogen or sulfur, e.g. cyclomethicone or phospholipids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
- A61K47/38—Cellulose; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1611—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1617—Organic compounds, e.g. phospholipids, fats
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Organic Chemistry (AREA)
- Immunology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Rheumatology (AREA)
- Physical Education & Sports Medicine (AREA)
- Inorganic Chemistry (AREA)
- Botany (AREA)
- Alternative & Traditional Medicine (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- Medical Informatics (AREA)
- Biotechnology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
Abstract
COMPOSIÇÕES DE CURCUMINA PARA OSTEOARTRITE E BEM-ESTAR DA ARTICULAÇÃO. A presente invenção refere-se a uma composição de curcumina estável para prevenção, melhora e manutenção da artrite, mais particularmente da osteoartrite. A composição de curcumina estável é compreendida por curcuminoides isolada ou juntamente com pelo menos um excipiente farmaceuticamente e/ou nutraceuticamente aceito para formar as composições de curcumina estável tendo aumento na absorção e biodisponibilidade. A composição é segura para consumo, possui estabilidade e biodisponibilidade aprimoradas devido à porcentagem seletiva de forma polimórfica amorfa e cristalina de curcumina juntamente com excipiente seletivo, tal como modificador de pH e/ou estabilizador e, opcionalmente, carreador hidrofílico, antioxidante, diluentes, agente antiaglomerante, emulsificante, gordura e tensoativo, que resulta na melhora dos sintomas de artrite e condições associadas, quando administrada a indivíduos que necessitem da mesma.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IN201921049620 | 2019-12-03 | ||
PCT/IB2020/061351 WO2021111312A1 (en) | 2019-12-03 | 2020-12-02 | Curcumin compositions for osteoarthritis and joint wellness |
Publications (1)
Publication Number | Publication Date |
---|---|
BR112022010900A2 true BR112022010900A2 (pt) | 2022-09-06 |
Family
ID=76221486
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR112022010900A BR112022010900A2 (pt) | 2019-12-03 | 2020-12-02 | Composições de curcumina para osteoartrite e bem-estar da articulação |
Country Status (8)
Country | Link |
---|---|
US (1) | US20230241006A1 (pt) |
EP (1) | EP4069266A4 (pt) |
JP (1) | JP2023504462A (pt) |
KR (1) | KR20220110497A (pt) |
CN (1) | CN114786699A (pt) |
AU (1) | AU2020398079A1 (pt) |
BR (1) | BR112022010900A2 (pt) |
WO (1) | WO2021111312A1 (pt) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2023096423A1 (ko) * | 2021-11-26 | 2023-06-01 | 가톨릭대학교 산학협력단 | 징크복합조성물 탑재 마이크로니들 패치를 이용한 항염증 조성물 |
Family Cites Families (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
PL1993365T3 (pl) * | 2006-03-06 | 2013-10-31 | Univ California | Preparaty z biodostępnych kurkuminoidów do leczenia choroby alzheimera oraz innych zaburzeń powiązanych z wiekiem |
JP2014503470A (ja) * | 2010-10-14 | 2014-02-13 | アボット ゲーエムベーハー ウント カンパニー カーゲー | クルクミノイド固体分散製剤 |
US8785380B2 (en) * | 2011-02-01 | 2014-07-22 | M/S Akay Flavours & Aromatics Pvt Ltd. | Formulation containing curcuminoids exhibiting enhanced bioavailability |
WO2012138907A2 (en) * | 2011-04-05 | 2012-10-11 | Translational Genomics Research Institute | Solid forms of curcumin |
WO2012156979A1 (en) * | 2011-05-16 | 2012-11-22 | Omniactive Health Technologies Ltd | A water soluble composition comprising curcumin having enhanced bioavailability and process thereof |
WO2013122988A1 (en) * | 2012-02-13 | 2013-08-22 | Imra America, Inc. | Amorphous medicinal fine particles produced by pulsed laser ablation in liquid and the production method thereof |
US20140010903A1 (en) * | 2012-07-04 | 2014-01-09 | Akay Flavours & Aromatics Pvt Ltd. | Curcuminoid composition with enhanced bioavailability and a process for its preparation |
US9504754B2 (en) * | 2013-03-15 | 2016-11-29 | South Dakota Board Of Regents | Curcuminoid complexes with enhanced stability, solubility and/or bioavailability |
US9724311B2 (en) * | 2014-04-18 | 2017-08-08 | Omniactive Health Technologies Limited | Curcumin compositions and uses thereof |
KR20170076496A (ko) * | 2015-12-24 | 2017-07-04 | (주)휴온스 | 용해성이 개선된 안정한 무정형 쿠르큐미노이드 고체분산체 조성물 및 이의 제조방법 |
CA3019165A1 (en) * | 2016-04-07 | 2017-10-12 | Medclear Healthcare Private Limited | Water soluble formulation (liquid) of curcuminoids and process thereof |
CN107308133A (zh) * | 2016-04-27 | 2017-11-03 | 周意 | 姜黄素药物制剂 |
WO2018211380A1 (en) * | 2017-05-17 | 2018-11-22 | Inventia Healthcare Private Limited | Curcuminoid compositions |
-
2020
- 2020-12-02 CN CN202080084274.7A patent/CN114786699A/zh active Pending
- 2020-12-02 JP JP2022532115A patent/JP2023504462A/ja active Pending
- 2020-12-02 AU AU2020398079A patent/AU2020398079A1/en active Pending
- 2020-12-02 BR BR112022010900A patent/BR112022010900A2/pt unknown
- 2020-12-02 WO PCT/IB2020/061351 patent/WO2021111312A1/en unknown
- 2020-12-02 KR KR1020227018949A patent/KR20220110497A/ko unknown
- 2020-12-02 US US17/778,953 patent/US20230241006A1/en active Pending
- 2020-12-02 EP EP20896958.4A patent/EP4069266A4/en active Pending
Also Published As
Publication number | Publication date |
---|---|
WO2021111312A1 (en) | 2021-06-10 |
US20230241006A1 (en) | 2023-08-03 |
CN114786699A (zh) | 2022-07-22 |
EP4069266A4 (en) | 2023-07-05 |
KR20220110497A (ko) | 2022-08-08 |
EP4069266A1 (en) | 2022-10-12 |
AU2020398079A1 (en) | 2022-06-23 |
JP2023504462A (ja) | 2023-02-03 |
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