BR112022009627A2 - Variantes de esqualeno hopeno ciclase (sch) - Google Patents

Variantes de esqualeno hopeno ciclase (sch)

Info

Publication number
BR112022009627A2
BR112022009627A2 BR112022009627A BR112022009627A BR112022009627A2 BR 112022009627 A2 BR112022009627 A2 BR 112022009627A2 BR 112022009627 A BR112022009627 A BR 112022009627A BR 112022009627 A BR112022009627 A BR 112022009627A BR 112022009627 A2 BR112022009627 A2 BR 112022009627A2
Authority
BR
Brazil
Prior art keywords
variants
sch
hopene cyclase
squalene hopene
cyclase
Prior art date
Application number
BR112022009627A
Other languages
English (en)
Portuguese (pt)
Inventor
EICHHORN Eric
Ullmann Christophe
Original Assignee
Givaudan Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Givaudan Sa filed Critical Givaudan Sa
Publication of BR112022009627A2 publication Critical patent/BR112022009627A2/pt

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/02Oxygen as only ring hetero atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/92Naphthofurans; Hydrogenated naphthofurans
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D311/00Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/78Ring systems having three or more relevant rings
    • C07D311/92Naphthopyrans; Hydrogenated naphthopyrans
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D313/00Heterocyclic compounds containing rings of more than six members having one oxygen atom as the only ring hetero atom
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/90Isomerases (5.)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/02Oxygen as only ring hetero atoms
    • C12P17/04Oxygen as only ring hetero atoms containing a five-membered hetero ring, e.g. griseofulvin, vitamin C
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/02Oxygen as only ring hetero atoms
    • C12P17/06Oxygen as only ring hetero atoms containing a six-membered hetero ring, e.g. fluorescein
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y504/00Intramolecular transferases (5.4)
    • C12Y504/99Intramolecular transferases (5.4) transferring other groups (5.4.99)
    • C12Y504/99017Squalene--hopene cyclase (5.4.99.17)

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Cosmetics (AREA)
  • Fats And Perfumes (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
BR112022009627A 2019-12-04 2020-12-03 Variantes de esqualeno hopeno ciclase (sch) BR112022009627A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB1917688.2A GB201917688D0 (en) 2019-12-04 2019-12-04 SHC enzymes and enzyme variants
PCT/EP2020/084491 WO2021110848A1 (en) 2019-12-04 2020-12-03 Squalene hopene cyclase (shc) variants

Publications (1)

Publication Number Publication Date
BR112022009627A2 true BR112022009627A2 (pt) 2022-08-09

Family

ID=69147249

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112022009627A BR112022009627A2 (pt) 2019-12-04 2020-12-03 Variantes de esqualeno hopeno ciclase (sch)

Country Status (10)

Country Link
US (2) US12416027B2 (https=)
EP (1) EP4069836A1 (https=)
JP (2) JP7760503B2 (https=)
CN (1) CN115052982A (https=)
BR (1) BR112022009627A2 (https=)
CO (1) CO2022008659A2 (https=)
GB (1) GB201917688D0 (https=)
IL (1) IL293275A (https=)
MX (1) MX2022005939A (https=)
WO (1) WO2021110848A1 (https=)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN119137269A (zh) 2022-03-17 2024-12-13 奇华顿股份有限公司 Shc酶和酶变体
WO2024112870A1 (en) * 2022-11-23 2024-05-30 Conagen Inc. Conversion of homofarnesol to ambroxide
CN115851863B (zh) * 2022-11-30 2023-07-25 北京大学深圳研究生院 一种海绵烷骨架化合物的制备方法及其应用

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19649655A1 (de) 1996-11-29 1998-06-04 Haarmann & Reimer Gmbh Syntheseenzyme für die Herstellung von Coniferylalkohol, Coniferylaldehyd, Ferulasäure, Vanillin und Vanillinsäure und deren Verwendung
DE19960106A1 (de) 1999-12-14 2001-06-21 Haarmann & Reimer Gmbh Enzyme und Gene für die Herstellung von Vanillin
JP5236233B2 (ja) 2007-09-04 2013-07-17 花王株式会社 (−)−アンブロキサンの製造方法
WO2010139719A2 (de) 2009-06-05 2010-12-09 Basf Se Biokatalytische herstellung von ambroxan
EP4112727A3 (de) 2010-11-17 2023-03-15 Basf Se Verfahren zur biokatalytischen cyclisierung von terpenen und darin einsetzbare cyclase-mutanten
WO2013156398A1 (de) 2012-04-16 2013-10-24 Basf Se Verbessertes verfahren zur herstellung von (3e, 7e)-homofarnesol
US20130273619A1 (en) 2012-04-16 2013-10-17 Basf Se Process for the Preparation of (3E, 7E)-Homofarnesol
JP5748381B1 (ja) 2014-07-31 2015-07-15 楽天株式会社 メッセージ処理装置、メッセージ処理方法、記録媒体およびプログラム
GB201507207D0 (en) * 2015-04-24 2015-06-10 Givaudan Sa Enzymes and applications thereof
GB201507170D0 (en) 2015-04-24 2015-06-10 Givaudan Sa Process
EP3816297A1 (de) * 2016-02-19 2021-05-05 Basf Se Biokatalytische zyklisierung von mehrfach ungesättigten carbonsäuren-verbindungen
GB201618090D0 (en) * 2016-10-26 2016-12-07 Givaudan Sa Product
JP2020508651A (ja) 2017-02-24 2020-03-26 インターナショナル フレーバーズ アンド フラグランシズ インコーポレイテッド スクアレンホペンシクラーゼ、およびアンブロキサンを生成するためのその使用
JP2019170350A (ja) 2018-03-30 2019-10-10 国立大学法人千葉大学 スクアレン消費酵素のスクリーニング方法及びスクアレン−ホペン環化酵素
GB201917694D0 (en) * 2019-12-04 2020-01-15 Givaudan Sa Enzyme mediated process

Also Published As

Publication number Publication date
CN115052982A (zh) 2022-09-13
CO2022008659A2 (es) 2022-07-19
JP2023504855A (ja) 2023-02-07
WO2021110848A1 (en) 2021-06-10
US12416027B2 (en) 2025-09-16
JP7760503B2 (ja) 2025-10-27
US20250361536A1 (en) 2025-11-27
IL293275A (en) 2022-07-01
MX2022005939A (es) 2022-09-09
JP2025188332A (ja) 2025-12-26
GB201917688D0 (en) 2020-01-15
US20230021613A1 (en) 2023-01-26
EP4069836A1 (en) 2022-10-12

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Legal Events

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B154 Notification of filing of divisional application [chapter 15.50 patent gazette]

Free format text: O PEDIDO FOI DIVIDIDO NO BR122023025399-0 PROTOCOLO 870230106658 EM 04/12/2023 13:13.