BR112022004920A2 - Sistemas e métodos para expressão de proteínas - Google Patents

Sistemas e métodos para expressão de proteínas

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Publication number
BR112022004920A2
BR112022004920A2 BR112022004920A BR112022004920A BR112022004920A2 BR 112022004920 A2 BR112022004920 A2 BR 112022004920A2 BR 112022004920 A BR112022004920 A BR 112022004920A BR 112022004920 A BR112022004920 A BR 112022004920A BR 112022004920 A2 BR112022004920 A2 BR 112022004920A2
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Brazil
Prior art keywords
protein
systems
methods
protein expression
enhancer
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BR112022004920A
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English (en)
Inventor
Mertins Barbara
Folliard Thomas
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Excepgen Inc
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Publication of BR112022004920A2 publication Critical patent/BR112022004920A2/pt

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    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
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    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
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  • Health & Medical Sciences (AREA)
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  • Proteomics, Peptides & Aminoacids (AREA)
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  • Gastroenterology & Hepatology (AREA)
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  • Peptides Or Proteins (AREA)

Abstract

SISTEMAS E MÉTODOS PARA EXPRESSÃO DE PROTEÍNAS. A presente divulgação fornece um sistema para a expressão da proteína alvo em conjunto com a proteína intensificadora. A proteína intensificadora pode ser uma proteína viral que bloqueia o transporte nucleocitoplasmático. Também são fornecidos polinucleotídeos, vetores e células compreendendo proteínas alvo e sequências de ácidos nucleicos de proteínas intensificadoras.
BR112022004920A 2019-09-16 2020-09-15 Sistemas e métodos para expressão de proteínas BR112022004920A2 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201962901043P 2019-09-16 2019-09-16
US202062970628P 2020-02-05 2020-02-05
PCT/US2020/050910 WO2021055369A1 (en) 2019-09-16 2020-09-15 Systems and methods for protein expression

Publications (1)

Publication Number Publication Date
BR112022004920A2 true BR112022004920A2 (pt) 2022-06-28

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BR112022004920A BR112022004920A2 (pt) 2019-09-16 2020-09-15 Sistemas e métodos para expressão de proteínas

Country Status (11)

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US (2) US20220307037A1 (pt)
EP (1) EP4031670A4 (pt)
JP (1) JP2022548644A (pt)
KR (1) KR20220098129A (pt)
CN (1) CN114761565A (pt)
AU (1) AU2020351130A1 (pt)
BR (1) BR112022004920A2 (pt)
CA (1) CA3153942A1 (pt)
IL (1) IL291284A (pt)
MX (1) MX2022002956A (pt)
WO (1) WO2021055369A1 (pt)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN117321209A (zh) * 2021-03-12 2023-12-29 伊克赛普根公司 用于蛋白质表达的系统和方法
WO2023183889A1 (en) * 2022-03-24 2023-09-28 Excepgen Inc. Compositions and methods for protein expression with rna
CN117942275A (zh) * 2022-10-31 2024-04-30 康码（上海）生物科技有限公司 一种基于病毒阻断剂的洗手液及其应用

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7741022B2 (en) * 2006-01-18 2010-06-22 Wisconsin Alumi Research Foundation Protein inhibitor of Ran activity and methods of use thereof
DE102008035152A1 (de) * 2008-07-28 2010-02-04 Evocatal Gmbh Chaperon-Toolbox
US9315825B2 (en) * 2010-03-29 2016-04-19 The Trustees Of The University Of Pennsylvania Pharmacologically induced transgene ablation system
CN104258398B (zh) * 2014-10-14 2017-12-22 中国科学技术大学 Drd1及其激动剂在制备治疗nlrp3炎症小体相关炎症性疾病药物中的用途
SG11201911572YA (en) * 2017-07-25 2020-02-27 Oxford Genetics Ltd Adenoviral vectors
CN117321209A (zh) * 2021-03-12 2023-12-29 伊克赛普根公司 用于蛋白质表达的系统和方法

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Publication number Publication date
WO2021055369A1 (en) 2021-03-25
JP2022548644A (ja) 2022-11-21
CA3153942A1 (en) 2021-03-25
CN114761565A (zh) 2022-07-15
KR20220098129A (ko) 2022-07-11
US20220307037A1 (en) 2022-09-29
US20230056404A1 (en) 2023-02-23
EP4031670A1 (en) 2022-07-27
EP4031670A4 (en) 2023-10-18
AU2020351130A1 (en) 2022-04-28
IL291284A (en) 2022-05-01
MX2022002956A (es) 2022-05-13

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