BR112022001196A2 - Inibição de yap para cicatrização de feridas - Google Patents

Inibição de yap para cicatrização de feridas

Info

Publication number
BR112022001196A2
BR112022001196A2 BR112022001196A BR112022001196A BR112022001196A2 BR 112022001196 A2 BR112022001196 A2 BR 112022001196A2 BR 112022001196 A BR112022001196 A BR 112022001196A BR 112022001196 A BR112022001196 A BR 112022001196A BR 112022001196 A2 BR112022001196 A2 BR 112022001196A2
Authority
BR
Brazil
Prior art keywords
wound
methods
yap
healing
individual
Prior art date
Application number
BR112022001196A
Other languages
English (en)
Portuguese (pt)
Inventor
Elizabeth Desjardins-Park Heather
Francis Davitt Michael
T Longaker Michael
Mimi Borrelli
Shamik Mascharak
Original Assignee
Univ Leland Stanford Junior
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Leland Stanford Junior filed Critical Univ Leland Stanford Junior
Publication of BR112022001196A2 publication Critical patent/BR112022001196A2/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/409—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil having four such rings, e.g. porphine derivatives, bilirubin, biliverdine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/14—Drugs for dermatological disorders for baldness or alopecia

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Dermatology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Cosmetics (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
BR112022001196A 2019-07-26 2020-07-24 Inibição de yap para cicatrização de feridas BR112022001196A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201962879369P 2019-07-26 2019-07-26
PCT/US2020/043420 WO2021021607A2 (en) 2019-07-26 2020-07-24 Yap inhibition for wound healing

Publications (1)

Publication Number Publication Date
BR112022001196A2 true BR112022001196A2 (pt) 2022-03-15

Family

ID=74229013

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112022001196A BR112022001196A2 (pt) 2019-07-26 2020-07-24 Inibição de yap para cicatrização de feridas

Country Status (10)

Country Link
US (1) US20220313658A1 (https=)
EP (1) EP4003334A4 (https=)
JP (1) JP2022541572A (https=)
KR (1) KR20220041154A (https=)
CN (1) CN114401718A (https=)
AU (1) AU2020320171B2 (https=)
BR (1) BR112022001196A2 (https=)
CA (1) CA3144185A1 (https=)
IL (1) IL289923A (https=)
WO (1) WO2021021607A2 (https=)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR102550631B1 (ko) * 2021-03-16 2023-07-03 (주)파인헬스케어 인공지능을 이용한 욕창 단계 평가 및 치료 추천을 제공하는 장치 및 방법
WO2023009439A1 (en) * 2021-07-30 2023-02-02 The Board Of Trustees Of The Leland Stanford Junior University Mechanotransduction disruption mediation in skin grafting methods and compositions for use in practicing the same
US20240366565A1 (en) * 2021-09-09 2024-11-07 The Board Of Trustees Of The Leland Stanford Junior University Use of Verteporfin to Modulate Wound Healing After an Ocular Surgical Procedure or Ocular Injury
CN114288474A (zh) * 2021-12-27 2022-04-08 湖北中部医疗科技有限公司 一种促毛囊再生用真皮层、人工皮肤及其制备方法
CA3248997A1 (en) * 2022-04-28 2023-11-02 The Board Of Trustees Of The Leland Stanford Junior University PIEZO-ELECTRIC INHIBITION FOR Wound Healing
CN116694089B (zh) * 2022-09-19 2024-03-26 广州贝奥吉因生物科技股份有限公司 一种用于抑制瘢痕的水凝胶及其制备方法和应用
CN116602265B (zh) * 2023-05-25 2024-05-14 北京工业大学 一种用于建立瘢痕疙瘩动物模型的智能控制系统及方法

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2532906T5 (es) * 2002-10-25 2022-03-23 Foamix Pharmaceuticals Ltd Espuma cosmética y farmacéutica
GB0823265D0 (en) * 2008-12-20 2009-01-28 Convatec Technologies Inc Antimicrobial Composition
DE102010009572A1 (de) * 2010-02-26 2011-09-01 Euroderm Gmbh Verfahren zum Begünstigen der Heilung von Hautwunden unter Verwendung der Zellen der Haarwurzelscheide, Präparat und Herstellverfahren
AU2011338530B2 (en) * 2010-12-06 2017-06-15 Follica, Inc. Methods for treating baldness and promoting hair growth
US9655967B2 (en) * 2011-12-09 2017-05-23 The Board Of Trustees Of The Leland Stanford Junior University Inhibition of focal adhesion kinase for control of scar tissue formation
KR101385196B1 (ko) * 2012-05-17 2014-04-14 주식회사 유니크메디케어 광 조사를 이용한 광감각제―펩타이드를 유효성분으로 포함하는 발모 개선 또는 촉진용 조성물 및 이를 이용한 방법
EP2858635A1 (en) * 2012-06-11 2015-04-15 The Regents of The University of California Inhibitors of hippo-yap signaling pathway
US20140086867A1 (en) * 2012-09-24 2014-03-27 Robert G. Matheny Systems, Compositions and Methods for the Treatment of Alopecia
IL248468A0 (en) * 2016-10-13 2017-01-31 Technion Res & Dev Foundation Use of caspase-3 inhibitors and caspase-3 activators in the manufacture of medicament for treating cancer and wound healing

Also Published As

Publication number Publication date
US20220313658A1 (en) 2022-10-06
WO2021021607A3 (en) 2021-04-08
EP4003334A2 (en) 2022-06-01
KR20220041154A (ko) 2022-03-31
WO2021021607A2 (en) 2021-02-04
CA3144185A1 (en) 2021-02-04
AU2020320171B2 (en) 2025-05-29
IL289923A (en) 2022-03-01
CN114401718A (zh) 2022-04-26
EP4003334A4 (en) 2023-08-16
JP2022541572A (ja) 2022-09-26
AU2020320171A1 (en) 2022-02-17

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Legal Events

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B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

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B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: EM VIRTUDE DO ARQUIVAMENTO PUBLICADO NA RPI 2841 DE 17-06-2025 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDO O ARQUIVAMENTO DO PEDIDO DE PATENTE, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013.