BR112021024621A2 - Método para controle de um processo de fermentação - Google Patents

Método para controle de um processo de fermentação

Info

Publication number
BR112021024621A2
BR112021024621A2 BR112021024621A BR112021024621A BR112021024621A2 BR 112021024621 A2 BR112021024621 A2 BR 112021024621A2 BR 112021024621 A BR112021024621 A BR 112021024621A BR 112021024621 A BR112021024621 A BR 112021024621A BR 112021024621 A2 BR112021024621 A2 BR 112021024621A2
Authority
BR
Brazil
Prior art keywords
fermentation
microorganism
dissolved
fermentation broth
fermentation process
Prior art date
Application number
BR112021024621A
Other languages
English (en)
Inventor
Leander Petersen
Kumar Nandy Subir
Original Assignee
Unibio As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Unibio As filed Critical Unibio As
Publication of BR112021024621A2 publication Critical patent/BR112021024621A2/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/26—Processes using, or culture media containing, hydrocarbons
    • C12N1/28—Processes using, or culture media containing, hydrocarbons aliphatic
    • C12N1/30—Processes using, or culture media containing, hydrocarbons aliphatic having five or less carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M29/00—Means for introduction, extraction or recirculation of materials, e.g. pumps
    • C12M29/06—Nozzles; Sprayers; Spargers; Diffusers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M29/00—Means for introduction, extraction or recirculation of materials, e.g. pumps
    • C12M29/18—External loop; Means for reintroduction of fermented biomass or liquid percolate
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M41/00—Means for regulation, monitoring, measurement or control, e.g. flow regulation
    • C12M41/30—Means for regulation, monitoring, measurement or control, e.g. flow regulation of concentration
    • C12M41/32—Means for regulation, monitoring, measurement or control, e.g. flow regulation of concentration of substances in solution
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M41/00—Means for regulation, monitoring, measurement or control, e.g. flow regulation
    • C12M41/40—Means for regulation, monitoring, measurement or control, e.g. flow regulation of pressure
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M41/00—Means for regulation, monitoring, measurement or control, e.g. flow regulation
    • C12M41/48—Automatic or computerized control
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales

Landscapes

  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Biomedical Technology (AREA)
  • Sustainable Development (AREA)
  • Analytical Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Computer Hardware Design (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Processing Of Solid Wastes (AREA)

Abstract

método para controle de um processo de fermentação. a presente invenção refere-se a um processo de fermentação para a fermentação de pelo menos um microrganismo, em que o processo de fermentação compreende as etapas de (a) permitir que um caldo de fermentação compreendendo pelo menos um microrganismo flua no reator de fermentação; (b) fornecer um substrato de carbono ao reator de fermentação permitindo que o substrato gasoso de carbono seja dissolvido, ou parcialmente dissolvido, no caldo de fermentação; (c) fornecer um substrato de nitrogênio ao reator de fermentação permitindo que o substrato gasoso de nitrogênio seja dissolvido, ou parcialmente dissolvido, no caldo de fermentação; e (d) manter uma concentração de nitrato do caldo de fermentação abaixo de 0,035 g/l, e/ou manter uma concentração de nitrato do caldo de fermentação inferior a 0,01 g de nitrato/g de biomassa; em que pelo menos um organismo metanotrófico compreende pelo menos um microrganismo metanotrófico.
BR112021024621A 2019-06-13 2020-06-11 Método para controle de um processo de fermentação BR112021024621A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DKPA201900714 2019-06-13
PCT/EP2020/066198 WO2020249670A1 (en) 2019-06-13 2020-06-11 Method for controlling a fermentation process

Publications (1)

Publication Number Publication Date
BR112021024621A2 true BR112021024621A2 (pt) 2022-04-26

Family

ID=71108565

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112021024621A BR112021024621A2 (pt) 2019-06-13 2020-06-11 Método para controle de um processo de fermentação

Country Status (9)

Country Link
US (2) US20220259552A1 (pt)
EP (1) EP3983526A1 (pt)
JP (1) JP2022536668A (pt)
CN (2) CN117106689A (pt)
AU (1) AU2020290764A1 (pt)
BR (1) BR112021024621A2 (pt)
CA (1) CA3141983A1 (pt)
MX (1) MX2021014602A (pt)
WO (1) WO2020249670A1 (pt)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA3187631A1 (en) * 2020-07-07 2022-01-13 Unibio A/S Process for producing single cell protein
WO2023242307A1 (en) 2022-06-17 2023-12-21 Unibio A/S Nucleic acid product and process
WO2023242308A1 (en) 2022-06-17 2023-12-21 Unibio A/S Oxidation stabilised biomass material and process
WO2024099967A2 (en) 2022-11-07 2024-05-16 Unibio A/S Attenuation of lipopolysaccharide-derived toxicity in a bacterial biomass

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DD149873A3 (de) * 1978-12-15 1981-08-05 Akad Wissenschaften Ddr Verfahren zur steuerung des kultivierungsprozesses von mikroorganismen
ATE356196T1 (de) 1999-05-18 2007-03-15 Ebbe Busch Larsen Fermenter in u-form und/oder u-förmige düse und verfahren zur ausführung eines fermentationsverfahrens
US7579163B2 (en) 2001-08-16 2009-08-25 Statoil Asa Method of fermentation
CA2746696C (en) 2008-12-15 2020-07-14 Ebbe Busch Larsen U-shape and/or nozzle u-loop fermenter and method of fermentation
MX2018005667A (es) 2015-11-09 2018-08-01 Unibio As Proceso para la fermentacion mejorada de un microorganismo.
EP3558025A1 (en) 2016-12-22 2019-10-30 Unibio A/S Removal of nucleic acids and fragments thereof from a biomass material
CA3053616A1 (en) 2017-03-01 2018-09-07 Unibio A/S Fermentation reactor and fermentation process
MX2019010195A (es) 2017-03-01 2019-10-02 Unibio As Nuevo medio de fermentacion para crecimiento de bacterias metanotrofas y metodo para producir dicho medio.

Also Published As

Publication number Publication date
WO2020249670A1 (en) 2020-12-17
US20240084247A1 (en) 2024-03-14
MX2021014602A (es) 2022-01-18
AU2020290764A1 (en) 2022-01-20
CA3141983A1 (en) 2020-12-17
JP2022536668A (ja) 2022-08-18
EP3983526A1 (en) 2022-04-20
CN114341345A (zh) 2022-04-12
US20220259552A1 (en) 2022-08-18
CN117106689A (zh) 2023-11-24

Similar Documents

Publication Publication Date Title
BR112021024621A2 (pt) Método para controle de um processo de fermentação
BR112018009343A8 (pt) método de aperfeiçoamento da produção de biomassa e/ou da taxa de crescimento de um micro-organismo em um processo de fermentação, tanque de fermentação e composição
BR112021024225A2 (pt) Método para otimização de um processo de fermentação
Akköse et al. Effects of ammonium ion, acetate and aerobic conditions on hydrogen production and expression levels of nitrogenase genes in Rhodobacter sphaeroides OU 001
BR112012014454A2 (pt) uso de promotores indutíveis na produção de metionina
JP2018532433A5 (pt)
BR112013015334A2 (pt) método de controle de crescimento de micro-organismos contaminantes em um processo de fermentação
CN109837322A (zh) 一种利用枯草芽孢杆菌生产维生素b2的简易发酵培养基
BR112022015849A2 (pt) Produção de etanol com um ou mais coprodutos em levedura
Hayashi et al. The nirQ gene, which is required for denitrification of Pseudomonas aeruginosa, can activate the RubisCO from Pseudomonas hydrogenothermophila
KR101731554B1 (ko) 배가스 내 이산화탄소를 이용하여 제조된 중탄산 버퍼를 활용한 광합성 미생물의 배양방법
BR112022013969A2 (pt) Controle de processo para bioconversões
Vadali et al. Enhanced isoamyl acetate production upon manipulation of the acetyl‐CoA node in Escherichia coli
MX354011B (es) Uso de vinaza en el proceso de sacarificacion de biomasa lignocelulosica.
KR102009554B1 (ko) 배가스 내 이산화탄소를 이용하여 제조된 중탄산 버퍼, 및 무기 인산염 버퍼를 활용한 광합성 미생물의 배양방법
Chapman et al. Improved methods for the cultivation of the chemolithoautotrophic bacterium Nitrosomonas europaea
BR112022013249A2 (pt) Método para recuperar etanol de um caldo de fermentação, e, aparelho para separar etanol de um caldo de fermentação
Galvanauskas et al. Model‐based optimization and pO2 control of fed‐batch Escherichia coli and Saccharomyces cerevisiae cultivation processes
EA202193203A1 (ru) Способ оптимизации процесса ферментации
BR112021018944A2 (pt) Fermentação melhorada de gases de efeito estufa
BR112019023845A2 (pt) processo de produção de um composto orgânico, micro-organismo geneticamente modificado e uso de um micro-organismo geneticamente modificado
MY159592A (en) Fermentative production of methionine hydroxy analog (mha)
PH12019501441A1 (en) Methods and systems using ionophores to control contamination in fermentation of gaseous substrates
BR112022014752A2 (pt) Processo para controlar proporções de ácidos orgânicos em processo de bioconversão de dióxido de carbono
Kerckhof et al. Functional stabilisation and partner selection during repeated co-culivation in a methanotrophic interactome