BR112021020247A2 - Composições e métodos para melhorar a saúde da pele e para o tratamento e prevenção de doenças, distúrbios e afecções associadas a micróbios patogênicos - Google Patents

Composições e métodos para melhorar a saúde da pele e para o tratamento e prevenção de doenças, distúrbios e afecções associadas a micróbios patogênicos

Info

Publication number
BR112021020247A2
BR112021020247A2 BR112021020247A BR112021020247A BR112021020247A2 BR 112021020247 A2 BR112021020247 A2 BR 112021020247A2 BR 112021020247 A BR112021020247 A BR 112021020247A BR 112021020247 A BR112021020247 A BR 112021020247A BR 112021020247 A2 BR112021020247 A2 BR 112021020247A2
Authority
BR
Brazil
Prior art keywords
compositions
methods
derived
disorders
skin health
Prior art date
Application number
BR112021020247A
Other languages
English (en)
Portuguese (pt)
Inventor
Ida Lister
M Brucker Robert
Sanjay Jain
Xuecheng Zhang
Original Assignee
Dermbiont Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dermbiont Inc filed Critical Dermbiont Inc
Publication of BR112021020247A2 publication Critical patent/BR112021020247A2/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66—Microorganisms or materials therefrom
    • A61K35/74—Bacteria
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66—Microorganisms or materials therefrom
    • A61K35/74—Bacteria
    • A61K35/741—Probiotics
    • A61K35/744—Lactic acid bacteria, e.g. enterococci, pediococci, lactococci, streptococci or leuconostocs
    • A61K35/747—Lactobacilli, e.g. L. acidophilus or L. brevis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A61K31/404—Indoles, e.g. pindolol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66—Microorganisms or materials therefrom
    • A61K35/74—Bacteria
    • A61K35/741—Probiotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66—Microorganisms or materials therefrom
    • A61K35/74—Bacteria
    • A61K35/741—Probiotics
    • A61K35/744—Lactic acid bacteria, e.g. enterococci, pediococci, lactococci, streptococci or leuconostocs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
    • A61K8/4906—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with one nitrogen as the only hetero atom
    • A61K8/4913—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with one nitrogen as the only hetero atom having five membered rings, e.g. pyrrolidone carboxylic acid
    • A61K8/492—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with one nitrogen as the only hetero atom having five membered rings, e.g. pyrrolidone carboxylic acid having condensed rings, e.g. indol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/99—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from microorganisms other than algae or fungi, e.g. protozoa or bacteria
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q11/00—Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
    • A61Q17/04—Topical preparations for affording protection against sunlight or other radiation; Topical sun tanning preparations
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A61Q19/08—Anti-ageing preparations
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q5/00—Preparations for care of the hair
    • A61Q5/02—Preparations for cleaning the hair
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Dermatology (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Birds (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Gerontology & Geriatric Medicine (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Virology (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Cosmetics (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicinal Preparation (AREA)
BR112021020247A 2019-04-09 2020-04-09 Composições e métodos para melhorar a saúde da pele e para o tratamento e prevenção de doenças, distúrbios e afecções associadas a micróbios patogênicos BR112021020247A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201962920010P 2019-04-09 2019-04-09
PCT/US2020/027556 WO2020210553A1 (en) 2019-04-09 2020-04-09 Compositions and methods for improving skin health and for the treatment and prevention of diseases, disorders and conditions associated with pathogenic microbes

Publications (1)

Publication Number Publication Date
BR112021020247A2 true BR112021020247A2 (pt) 2021-12-21

Family

ID=70476522

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112021020247A BR112021020247A2 (pt) 2019-04-09 2020-04-09 Composições e métodos para melhorar a saúde da pele e para o tratamento e prevenção de doenças, distúrbios e afecções associadas a micróbios patogênicos

Country Status (12)

Country Link
US (5) US20220160617A1 (https=)
EP (1) EP3952848A1 (https=)
JP (1) JP2022526446A (https=)
KR (1) KR20220003539A (https=)
CN (1) CN113853198A (https=)
AU (1) AU2020271885A1 (https=)
BR (1) BR112021020247A2 (https=)
CA (1) CA3132858A1 (https=)
IL (1) IL287032A (https=)
MX (1) MX2021012391A (https=)
SG (1) SG11202111168UA (https=)
WO (1) WO2020210553A1 (https=)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2658897T3 (es) 2011-08-24 2018-03-12 Novan, Inc. Macromoléculas de liberación de óxido nítrico ajustables que tienen múltiples estructuras donantes de óxido nítrico
US11813284B2 (en) 2013-08-08 2023-11-14 Novan, Inc. Topical compositions and methods of using the same
US10322082B2 (en) 2014-07-11 2019-06-18 Novan, Inc. Topical antiviral compositions and methods of using the same
SG11202111168UA (en) * 2019-04-09 2021-11-29 Dermbiont Inc Compositions and methods for improving skin health and for the treatment and prevention of diseases, disorders and conditions associated with pathogenic microbes
US11517597B2 (en) * 2020-09-29 2022-12-06 Chambio Co., Ltd. Method for improving skin condition with postbiotic extract
CN112891343B (zh) * 2021-03-22 2022-04-01 华中农业大学 3-吲哚乙腈在制备抑制新型冠状病毒SARS-CoV-2药物中的应用
TWI890918B (zh) * 2022-01-24 2025-07-21 耀然實業股份有限公司 私密處保養組成物、私密處保養產品及私密處用品
CN114705800A (zh) * 2022-03-25 2022-07-05 重庆市公共卫生医疗救治中心 尿液中生物标志物检测试剂在制备新冠肺炎病毒无症状感染者筛查试剂盒中的用途
AU2023271525A1 (en) * 2022-05-16 2024-12-05 Maruho Co., Ltd. Composition for treating ringworm
US20260021219A1 (en) * 2022-09-30 2026-01-22 Kimberly-Clark Worldwide, Inc. Methods and absorbent articles for inhibiting fecal protease activity
EP4438052A1 (en) * 2023-03-30 2024-10-02 FytagoLife B.V. Plant extract for use in treatment of a fungal infection
KR20260049280A (ko) * 2023-08-07 2026-04-13 로레알 피부 항-노화 치료를 위한 새로운 조성물
KR20250104680A (ko) * 2023-12-29 2025-07-08 한국생명공학연구원 잔티노박테리움 속 균주 또는 비올라세인을 포함하는 발모 촉진 또는 탈모 예방 또는 치료용 조성물
WO2025179157A1 (en) 2024-02-23 2025-08-28 Imvela Corp. Compositions containing indole-derived metabolites and methods of use thereof

Family Cites Families (52)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3261761A (en) 1962-05-07 1966-07-19 Arthur W Anderson Method of freeze drying bacterial cultures
US4205132A (en) 1978-07-17 1980-05-27 Microlife Technics, Inc. Lyophilization of bacteria
EP0045718A3 (de) 1980-07-25 1983-01-19 Ciba-Geigy Ag Nasalpräparate und Verfahren zu deren Herstellung
US4900348A (en) 1983-08-02 1990-02-13 The Ohio State University Research Foundation Production of disease suppresive compost and container media, and microorganism culture for use therein
US5081225A (en) 1989-02-09 1992-01-14 E. R. Squibb & Sons, Inc. Gram-positive and gram-negative antibacterial compounds from the microorganism, janthinobacterium lividum
JPH05194141A (ja) 1992-01-14 1993-08-03 Mitsubishi Kasei Corp 化粧料
JPH06247964A (ja) 1993-02-22 1994-09-06 Snow Brand Milk Prod Co Ltd 新規生理活性物質ｈｓ−１及びその製造方法
IT1296148B1 (it) 1996-11-22 1999-06-09 Renata Maria Anna Ve Cavaliere Uso di batteri lattici per accrescere il livello delle ceramidi della pelle e delle mucose, e composizioni dermatologiche e cosmetiche atte
US5888396A (en) 1996-12-17 1999-03-30 Perriello; Felix Anthony Bioremediation of pollutants with butane-utilizing bacteria
US6244346B1 (en) 1996-12-17 2001-06-12 Global Biosciences, Inc. Method and apparatus for reducing fouling of injection and recovery wells
US6716435B1 (en) 1997-04-18 2004-04-06 Ganeden Biotech, Inc. Absorbent product containing absorbent structure and Bacillus coagulans
US6645506B1 (en) 1997-04-18 2003-11-11 Ganeden Biotech, Inc. Topical compositions containing extracellular products of Pseudomonas lindbergii and Emu oil
ATE493139T1 (de) 1997-04-18 2011-01-15 Ganeden Biotech Inc Oberflächige verwendung von probiotischen bacillussporen zur verhinderung oder bekämpfung von mikrobiellen infektionen
US7507402B1 (en) 1997-04-18 2009-03-24 Ganeden Biotech, Inc. Topical use of probiotic Bacillus spores to prevent or control microbial infections
US7374753B1 (en) 1997-06-03 2008-05-20 Ganeden Biotech, Inc. Probiotic lactic acid bacterium to treat bacterial infections associated with SIDS
US6811786B1 (en) 1999-04-01 2004-11-02 Ganeden Biotech, Inc. Methods for reducing cholesterol using Bacillus coagulans spores, systems and compositions
US7767203B2 (en) 1998-08-07 2010-08-03 Ganeden Biotech, Inc. Methods for the dietary management of irritable bowel syndrome and carbohydrate malabsorption
US6461607B1 (en) 1998-08-24 2002-10-08 Ganeden Biotech, Inc. Probiotic, lactic acid-producing bacteria and uses thereof
US6224863B1 (en) 1998-10-30 2001-05-01 University Of South Carolina Antibiotic composition from alcaligenes species and method for making and using the same
IT1306716B1 (it) 1999-06-21 2001-10-02 Mendes S U R L Associazione di batteri lattici e suo uso per la prevenzione e/o iltrattamento terapeutico di infezioni e di stati infiammatori.
EP1212093B1 (en) 1999-08-26 2004-07-07 Ganeden Biotech, Inc. Use of emu oil as a carrier for antifungal, antibacterial and antiviral medications
US6849256B1 (en) 1999-11-08 2005-02-01 Ganeden Biotech Incorporated Inhibition of pathogens by probiotic bacteria
JP4554745B2 (ja) 1999-11-18 2010-09-29 日本合成化学工業株式会社 乳化重合用分散剤およびその用途
JP2001269699A (ja) 2000-03-24 2001-10-02 Japan Science & Technology Corp 硝酸汚染地下水の直接浄化方法
US20030072829A1 (en) 2001-01-05 2003-04-17 Austin Richard M. Bacterial isolates from organisms that respire at least partially through their skin and biologically active extracts derived therefrom
AUPS057102A0 (en) 2002-02-15 2002-03-07 Vri Biomedical Ltd Compositions and methods for treatment of skin disorders
WO2003074660A2 (en) 2002-02-28 2003-09-12 New England Biolabs, Inc. Modified chitin binding domain and uses thereof
US20040243076A1 (en) 2003-05-13 2004-12-02 Sca Hygiene Products Ab Hygiene product with a probiotic composition
US7244607B2 (en) 2003-10-01 2007-07-17 The United States Of America, As Represented By The Secretary Of Agriculture Chromobacterium subtsugae sp. nov. for control of insect pests
JP2005126375A (ja) 2003-10-24 2005-05-19 Shimomura Kinue 乳酸飲料水
MXPA06015184A (es) 2004-06-23 2007-11-22 Nestec Sa Procedimiento y composiciones utiles para prevenir y/o tratar pieles sensibles y/o secas.
JP2006253864A (ja) 2005-03-09 2006-09-21 Fujitsu Ltd データ蓄積型転送方法及びそのシステム並びに装置
US7385203B2 (en) 2005-06-07 2008-06-10 Hitachi, Ltd. Charged particle beam extraction system and method
KR100802494B1 (ko) 2006-02-24 2008-02-12 (주)한국바이오케미칼 비올라세인을 함유하는 해충 방제제, 항진균제 및 그의제조방법
JP2007227290A (ja) 2006-02-27 2007-09-06 Canon Inc 画像表示装置および映像受信表示装置
CN101659698B (zh) * 2008-08-26 2012-03-28 清华大学 紫色杆菌素合成相关蛋白质系统及其编码基因簇与应用
CN101386834A (zh) * 2008-10-28 2009-03-18 清华大学 生产紫色杆菌素的方法及重组菌
JP2010113169A (ja) 2008-11-07 2010-05-20 Kagawa Univ 凸版印刷用版材及びその製造方法
US8506952B2 (en) * 2009-07-03 2013-08-13 James Madison Innovations, Inc. Probiotic compositions and process thereof
JP2011152687A (ja) 2010-01-27 2011-08-11 Seiko Epson Corp 液体吐出装置の調整方法及び補正値の算出方法
WO2012098358A1 (en) 2011-01-20 2012-07-26 Biopharma Technology Ltd Freeze drying method
KR101982491B1 (ko) 2011-08-30 2019-05-27 아카데미쉬 메디쉬 센트륨 인슐린 저항 예방 및/또는 치료 방법
HUE029357T2 (en) 2012-05-08 2017-02-28 Adaptive Biotechnologies Corp Preparations and devices for measuring and calibrating amplification distortion in multiplex PCR reactions
WO2014029578A1 (en) 2012-08-24 2014-02-27 Haldor Topsøe A/S Method and catalyzed filter element with improved alkali-resistance for flue gas cleaning
WO2014145958A2 (en) 2013-03-15 2014-09-18 Seres Health, Inc. Network-based microbial compositions and methods
CN105979952B (zh) 2013-11-25 2022-04-08 赛里斯治疗公司 协同细菌组合物以及其制造方法和用途
EP4299122A3 (en) 2014-05-07 2024-03-27 The Regents of The University of California Compositions and methods for treating skin and mucous membrane diseases
CN104293703A (zh) * 2014-09-22 2015-01-21 中国农业科学院农产品加工研究所 一种高产紫色杆菌素的兰黑紫色杆菌及其应用
WO2019118984A2 (en) * 2017-12-15 2019-06-20 Solarea Bio, Inc. Microbial compositions and methods for treating type 2 diabetes, obesity, and metabolic syndrome
UA126440C2 (uk) 2018-12-27 2022-10-05 Ігор Семенович Марков Полівалентна комбінована інактивована рідка вакцина проти збудників бактеріальних і грибкових захворювань сечостатевої системи, спосіб її виготовлення і спосіб лікування та профілактики нею
WO2020179999A1 (ko) 2019-03-07 2020-09-10 씨제이제일제당(주) 바실러스 서브틸리스 cjbs303 및 이를 포함하는 조성물
SG11202111168UA (en) * 2019-04-09 2021-11-29 Dermbiont Inc Compositions and methods for improving skin health and for the treatment and prevention of diseases, disorders and conditions associated with pathogenic microbes

Also Published As

Publication number Publication date
US20220160617A1 (en) 2022-05-26
JP2022526446A (ja) 2022-05-24
WO2020210553A1 (en) 2020-10-15
US12064459B2 (en) 2024-08-20
CA3132858A1 (en) 2020-10-15
SG11202111168UA (en) 2021-11-29
EP3952848A1 (en) 2022-02-16
AU2020271885A1 (en) 2021-11-25
IL287032A (en) 2021-12-01
US11040077B2 (en) 2021-06-22
KR20220003539A (ko) 2022-01-10
US20210386802A1 (en) 2021-12-16
US20200345799A1 (en) 2020-11-05
CN113853198A (zh) 2021-12-28
MX2021012391A (es) 2022-01-18
US20210361725A1 (en) 2021-11-25
US20250295713A1 (en) 2025-09-25

Similar Documents

Publication Publication Date Title
BR112021020247A2 (pt) Composições e métodos para melhorar a saúde da pele e para o tratamento e prevenção de doenças, distúrbios e afecções associadas a micróbios patogênicos
PH12021550187A1 (en) Pyrrolopyrimidine itk inhibitors
MX2022015613A (es) Composiciones de benzofurano beneficiosas para trastornos mentales o mejoramiento mental.
BR112022000019A2 (pt) Composto da fórmula, composição farmacêutica e método de tratamento de câncer
MX2017015938A (es) Inhibidores de ezh2 para el tratar linfomas.
BR112017024331A2 (pt) composto, composição farmacêutica, método de tratamento de um humano, métodos para inibir a atividade de uma proteína ido1, o crescimento ou a proliferação de células cancerosas, e a imunossupressão em um paciente, e de tratamento de uma doença, e, uso de um composto
MX2023003677A (es) Inhibidores de hidroxiesteroide 17beta- deshidrogenasa 13 (hsd17b13) y usos de estos.
MX2022016422A (es) Inhibidores de glicolato oxidasa para el tratamiento de enfermedades.
MX2023003678A (es) Inhibidores de hidroxiesteroide 17beta- deshidrogenasa 13 (hsd17b13) y usos de estos.
ECSP19070369A (es) Derivados de indolina sustituidos como inhibidores de la replicación vírica de dengue
BR112019024264A2 (pt) Antimitoscinas: inibidores direcionados da biogênese mitoconcrial para erradicação de células-tronco de câncer
BR112018002046A2 (pt) métodos de tratamento da síndrome de lennox-gastaut usando fenfluramina
BR112017011923A2 (pt) bactéria modificada para tratar doenças associadas com hiperamonemia
ECSP19083621A (es) Derivados de indolina sustituidos como inhibidores de la replicación vírica de dengue
MX2025002953A (es) Derivados heteroaromaticos y aromaticos heterobiciclicos para el tratamiento de trastornos relacionados con ferroptosis
ECSP19070413A (es) Derivados de indolina sustituidos como inhibidores de la replicación vírica de dengue
ECSP19083640A (es) Derivados de indolina sustituidos como inhibidores de la replicación vírica de dengue
MX2025005941A (es) Moduladores de la actividad tnf-\03b1
MX2023009723A (es) Inhibidores de tyk2 y sus usos.
MX2022005624A (es) Tratamiento de vomito y nausea con una dosis minima de olanzapina.
MX2023003675A (es) Inhibidores de hidroxiesteroide 17beta-deshidrogenasa 13 (hsd17b13) y usos de estos.
BR112022008938A2 (pt) Derivados de 1-aminossulfonil-2-carboxipirrol como inibidores de metalo-beta-lactamase
WO2019010301A8 (en) Treatment of heart disease by inhibition of the action of muscle a-kinase anchoring protein (makap)
WO2020068950A8 (en) Hdac1,2 inhibitors
WO2021242844A8 (en) Grk2 inhibitors and uses thereof

Legal Events

Date Code Title Description
B06W Patent application suspended after preliminary examination (for patents with searches from other patent authorities) chapter 6.23 patent gazette]