BR112021016747A2 - Método para tratamento de um meloma múltiplo - Google Patents

Método para tratamento de um meloma múltiplo Download PDF

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Publication number
BR112021016747A2
BR112021016747A2 BR112021016747-1A BR112021016747A BR112021016747A2 BR 112021016747 A2 BR112021016747 A2 BR 112021016747A2 BR 112021016747 A BR112021016747 A BR 112021016747A BR 112021016747 A2 BR112021016747 A2 BR 112021016747A2
Authority
BR
Brazil
Prior art keywords
compound
multiple myeloma
subject
pharmaceutical composition
individual
Prior art date
Application number
BR112021016747-1A
Other languages
English (en)
Portuguese (pt)
Inventor
Marla L. Weetall
Liangxian Cao
Arnold Bolomsky
Heinz Ludwig
Original Assignee
Ptc Therapeutics, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ptc Therapeutics, Inc. filed Critical Ptc Therapeutics, Inc.
Publication of BR112021016747A2 publication Critical patent/BR112021016747A2/pt

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/506Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
BR112021016747-1A 2019-02-28 2020-02-26 Método para tratamento de um meloma múltiplo BR112021016747A2 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201962812002P 2019-02-28 2019-02-28
US62/812,002 2019-02-28
PCT/US2020/019884 WO2020176610A1 (en) 2019-02-28 2020-02-26 Method for treating a multiple myeloma

Publications (1)

Publication Number Publication Date
BR112021016747A2 true BR112021016747A2 (pt) 2021-10-19

Family

ID=72238680

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112021016747-1A BR112021016747A2 (pt) 2019-02-28 2020-02-26 Método para tratamento de um meloma múltiplo

Country Status (11)

Country Link
US (1) US20220143016A1 (https=)
EP (1) EP3931196A4 (https=)
JP (1) JP2022521801A (https=)
CN (1) CN113710670A (https=)
AU (1) AU2020227748A1 (https=)
BR (1) BR112021016747A2 (https=)
CA (1) CA3131249A1 (https=)
EA (1) EA202192117A1 (https=)
IL (1) IL285800A (https=)
MX (1) MX2021010398A (https=)
WO (1) WO2020176610A1 (https=)

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH593266A5 (https=) * 1973-09-20 1977-11-30 Delalande Sa
EP1351691A4 (en) * 2000-12-12 2005-06-22 Cytovia Inc SUBSTITUTED 2-ARYL-4-ARYLAMINOPYRIMIDINES AND ANALOGUES AS ACTIVATORS OF CASPASES AND APOPTOSIS INDUCERS, AND USE THEREOF
EP2624818B1 (en) * 2010-10-05 2017-04-05 Fresenius Kabi USA, LLC Bortezomib formulations stabilised with boric acid
NZ746607A (en) * 2012-11-21 2019-11-29 Ptc Therapeutics Inc Substituted reverse pyrimidine bmi-1 inhibitors
EA034866B1 (ru) * 2013-08-30 2020-03-31 ПиТиСи ТЕРАПЬЮТИКС, ИНК. Замещенные пиримидиновые ингибиторы bmi-1
EP3836932A2 (en) * 2018-08-17 2021-06-23 PTC Therapeutics, Inc. Method for treating pancreatic cancer
US20220185795A1 (en) * 2019-03-11 2022-06-16 Ptc Therapeutics, Inc. Compound form having enhanced bioavailability and formulations thereof

Also Published As

Publication number Publication date
AU2020227748A1 (en) 2021-09-16
CN113710670A (zh) 2021-11-26
WO2020176610A8 (en) 2021-08-12
IL285800A (en) 2021-10-31
EP3931196A4 (en) 2022-12-14
JP2022521801A (ja) 2022-04-12
CA3131249A1 (en) 2020-09-03
EA202192117A1 (ru) 2021-11-23
WO2020176610A1 (en) 2020-09-03
EP3931196A1 (en) 2022-01-05
MX2021010398A (es) 2022-01-18
US20220143016A1 (en) 2022-05-12

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Legal Events

Date Code Title Description
B15K Others concerning applications: alteration of classification

Free format text: AS CLASSIFICACOES ANTERIORES ERAM: C07D 471/04 , C07D 403/04 , C07D 487/04

Ipc: C07D 471/04 (2006.01), C07D 403/04 (2006.01), C07D

B06W Patent application suspended after preliminary examination (for patents with searches from other patent authorities) chapter 6.23 patent gazette]
B11B Dismissal acc. art. 36, par 1 of ipl - no reply within 90 days to fullfil the necessary requirements