BR112021016182A2 - Composição imunológica multivalente, e, método para induzir uma resposta imune contra uma pluralidade de vírus da influenza equina - Google Patents
Composição imunológica multivalente, e, método para induzir uma resposta imune contra uma pluralidade de vírus da influenza equinaInfo
- Publication number
- BR112021016182A2 BR112021016182A2 BR112021016182A BR112021016182A BR112021016182A2 BR 112021016182 A2 BR112021016182 A2 BR 112021016182A2 BR 112021016182 A BR112021016182 A BR 112021016182A BR 112021016182 A BR112021016182 A BR 112021016182A BR 112021016182 A2 BR112021016182 A2 BR 112021016182A2
- Authority
- BR
- Brazil
- Prior art keywords
- influenza virus
- equine influenza
- inducing
- immune response
- equine
- Prior art date
Links
- 241000712461 unidentified influenza virus Species 0.000 title abstract 6
- 241000283073 Equus caballus Species 0.000 title abstract 5
- 239000000203 mixture Substances 0.000 title abstract 4
- 230000001900 immune effect Effects 0.000 title abstract 2
- 230000028993 immune response Effects 0.000 title abstract 2
- 230000001939 inductive effect Effects 0.000 title abstract 2
- 229960001226 live attenuated influenza Drugs 0.000 abstract 3
- 241001428841 Equine influenza virus H3N8 Species 0.000 abstract 2
- 239000000427 antigen Substances 0.000 abstract 2
- 102000036639 antigens Human genes 0.000 abstract 2
- 108091007433 antigens Proteins 0.000 abstract 2
- 230000002238 attenuated effect Effects 0.000 abstract 2
- 229940124873 Influenza virus vaccine Drugs 0.000 abstract 1
- 229960005486 vaccine Drugs 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
- A61K39/145—Orthomyxoviridae, e.g. influenza virus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/525—Virus
- A61K2039/5254—Virus avirulent or attenuated
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/54—Medicinal preparations containing antigens or antibodies characterised by the route of administration
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/545—Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/55—Medicinal preparations containing antigens or antibodies characterised by the host/recipient, e.g. newborn with maternal antibodies
- A61K2039/552—Veterinary vaccine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/70—Multivalent vaccine
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/16011—Orthomyxoviridae
- C12N2760/16034—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/16011—Orthomyxoviridae
- C12N2760/16061—Methods of inactivation or attenuation
- C12N2760/16062—Methods of inactivation or attenuation by genetic engineering
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Virology (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Pulmonology (AREA)
- Epidemiology (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- Immunology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Molecular Biology (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Abstract
composição imunológica multivalente, e, método para induzir uma resposta imune contra uma pluralidade de vírus da influenza equina. a presente invenção fornece composições e métodos relacionados a vacinas do vírus vivo atenuado da influenza equina. em um aspecto, a invenção se refere a uma composição compreendendo uma vacina de vírus atenuado da influenza equina multivalente compreendendo um primeiro vírus influenza vivo atenuado que expressa um ou mais antígenos de um vírus da influenza equina h3n8 de clado 1; e um segundo vírus influenza vivo atenuado que expressa um ou mais antígenos de um vírus da influenza equina h3n8 de clado 2, em que o segundo vírus influenza vivo atenuado expressa ha, na ou uma combinação destes de a/equine/lancashire/1/2016 h3n8.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201962811112P | 2019-02-27 | 2019-02-27 | |
PCT/US2020/020050 WO2020176709A1 (en) | 2019-02-27 | 2020-02-27 | Multivalent live-attenuated influenza vaccine for prevention and control of equine influenza virus (eiv) in horses |
Publications (1)
Publication Number | Publication Date |
---|---|
BR112021016182A2 true BR112021016182A2 (pt) | 2021-11-03 |
Family
ID=70005787
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR112021016182A BR112021016182A2 (pt) | 2019-02-27 | 2020-02-27 | Composição imunológica multivalente, e, método para induzir uma resposta imune contra uma pluralidade de vírus da influenza equina |
Country Status (8)
Country | Link |
---|---|
US (1) | US20220133877A1 (pt) |
EP (1) | EP3930749A1 (pt) |
CN (1) | CN113905759A (pt) |
AR (1) | AR118202A1 (pt) |
BR (1) | BR112021016182A2 (pt) |
CA (1) | CA3130781A1 (pt) |
MX (1) | MX2021010343A (pt) |
WO (1) | WO2020176709A1 (pt) |
Family Cites Families (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5166057A (en) | 1989-08-28 | 1992-11-24 | The Mount Sinai School Of Medicine Of The City University Of New York | Recombinant negative strand rna virus expression-systems |
US5854037A (en) | 1989-08-28 | 1998-12-29 | The Mount Sinai School Of Medicine Of The City University Of New York | Recombinant negative strand RNA virus expression systems and vaccines |
DE69532369T3 (de) | 1994-07-18 | 2010-11-04 | Conzelmann, Karl-Klaus, Prof. Dr. | Rekombinantes infektiöses nicht-in-Segmente-geteiltes, negativ-Strange-RNS-Virus |
US7153510B1 (en) | 1995-05-04 | 2006-12-26 | Yale University | Recombinant vesiculoviruses and their uses |
DE69510207T3 (de) | 1995-08-09 | 2007-02-15 | Schweiz. Serum- & Impfinstitut Bern | Verfahren zur Herstellung von infektiösen minussträngigen RNA-Viren |
AU727923B2 (en) | 1995-09-27 | 2001-01-04 | Government Of The United States Of America, As Represented By The Secretary Of The Department Of Health And Human Services, The | Production of infectious respiratory syncytial virus from cloned nucleotide sequences |
WO1998002530A1 (en) | 1996-07-15 | 1998-01-22 | The Government Of The United States Of America, As Represented By The Department Of Health And Human Services | Production of attenuated respiratory syncytial virus vaccines from cloned nucleotide sequences |
EP0932684A2 (en) | 1996-09-27 | 1999-08-04 | American Cyanamid Company | 3' genomic promoter region and polymerase gene mutations responsible for attenuation in viruses of the order designated mononegavirales |
ATE501259T1 (de) | 1997-05-23 | 2011-03-15 | Us Of America As Represented By The Secretary Of The Dept Of Health And Human Services | Herstellung attenuierter parainfluenza-virus impfstoffe aus klonierten nukleotidsequenzen |
JP4434478B2 (ja) | 1997-07-11 | 2010-03-17 | イエール ユニバーシティー | リエンジニアリングされた外被を有するラブドウイルス |
EP1015594A1 (en) | 1997-09-19 | 2000-07-05 | American Cyanamid Company | Attenuated respiratory syncytial viruses |
PL212212B1 (pl) | 2001-07-27 | 2012-08-31 | Wyeth Corp | Kompozycja szczepionki przeciwko zakażeniu wirusem Zachodniego Nilu, kompozycja końskiej szczepionki, szczepionka wirusa Zachodniego Nilu oraz zastosowania |
MX2018014955A (es) * | 2016-06-03 | 2019-05-13 | Univ Rochester | Vacunas atenuadas vivas del virus de la influenza equina. |
-
2020
- 2020-02-27 MX MX2021010343A patent/MX2021010343A/es unknown
- 2020-02-27 BR BR112021016182A patent/BR112021016182A2/pt not_active Application Discontinuation
- 2020-02-27 CN CN202080020053.3A patent/CN113905759A/zh active Pending
- 2020-02-27 EP EP20714405.6A patent/EP3930749A1/en active Pending
- 2020-02-27 US US17/434,489 patent/US20220133877A1/en active Pending
- 2020-02-27 WO PCT/US2020/020050 patent/WO2020176709A1/en unknown
- 2020-02-27 CA CA3130781A patent/CA3130781A1/en active Pending
- 2020-02-27 AR ARP200100536A patent/AR118202A1/es unknown
Also Published As
Publication number | Publication date |
---|---|
WO2020176709A1 (en) | 2020-09-03 |
CN113905759A (zh) | 2022-01-07 |
AR118202A1 (es) | 2021-09-22 |
CA3130781A1 (en) | 2020-09-03 |
US20220133877A1 (en) | 2022-05-05 |
MX2021010343A (es) | 2022-01-18 |
EP3930749A1 (en) | 2022-01-05 |
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Legal Events
Date | Code | Title | Description |
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B11A | Dismissal acc. art.33 of ipl - examination not requested within 36 months of filing | ||
B11Y | Definitive dismissal - extension of time limit for request of examination expired [chapter 11.1.1 patent gazette] |