BR112021002760A2 - tratamento de malignidades de célula b - Google Patents

tratamento de malignidades de célula b Download PDF

Info

Publication number
BR112021002760A2
BR112021002760A2 BR112021002760-2A BR112021002760A BR112021002760A2 BR 112021002760 A2 BR112021002760 A2 BR 112021002760A2 BR 112021002760 A BR112021002760 A BR 112021002760A BR 112021002760 A2 BR112021002760 A2 BR 112021002760A2
Authority
BR
Brazil
Prior art keywords
nr1br1c
compound
nr1as
nr1ac
mixture
Prior art date
Application number
BR112021002760-2A
Other languages
English (en)
Portuguese (pt)
Inventor
Daniel P. Gold
Original Assignee
Mei Pharma, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mei Pharma, Inc. filed Critical Mei Pharma, Inc.
Publication of BR112021002760A2 publication Critical patent/BR112021002760A2/pt

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/53751,4-Oxazines, e.g. morpholine
    • A61K31/53771,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/02Antineoplastic agents specific for leukemia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
BR112021002760-2A 2018-08-14 2019-08-13 tratamento de malignidades de célula b BR112021002760A2 (pt)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US201862718929P 2018-08-14 2018-08-14
US62/718,929 2018-08-14
US201862775797P 2018-12-05 2018-12-05
US62/775,797 2018-12-05
US201962836511P 2019-04-19 2019-04-19
US62/836,511 2019-04-19
PCT/US2019/046411 WO2020036999A1 (en) 2018-08-14 2019-08-13 Treatment of b cell malignancies

Publications (1)

Publication Number Publication Date
BR112021002760A2 true BR112021002760A2 (pt) 2021-05-11

Family

ID=69525845

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112021002760-2A BR112021002760A2 (pt) 2018-08-14 2019-08-13 tratamento de malignidades de célula b

Country Status (14)

Country Link
US (1) US20210299134A1 (https=)
EP (1) EP3836935A4 (https=)
JP (1) JP2021534115A (https=)
KR (1) KR20210043635A (https=)
CN (1) CN112888441A (https=)
AU (1) AU2019321432A1 (https=)
BR (1) BR112021002760A2 (https=)
CA (1) CA3109184A1 (https=)
IL (1) IL280726A (https=)
MA (1) MA53236A (https=)
MX (1) MX2021001606A (https=)
SG (1) SG11202101450VA (https=)
TW (1) TW202021591A (https=)
WO (1) WO2020036999A1 (https=)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI572599B (zh) 2011-03-28 2017-03-01 Mei製藥公司 (α-經取代之芳烷胺基及雜芳烷胺基)嘧啶基及1,3,5-三基苯并咪唑,其醫藥組合物及其在治療增生性疾病之用途
US11304953B2 (en) 2017-05-23 2022-04-19 Mei Pharma, Inc. Combination therapy
KR20200041358A (ko) 2017-08-14 2020-04-21 메이 파마, 아이엔씨. 병용 요법

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2011338530B2 (en) * 2010-12-06 2017-06-15 Follica, Inc. Methods for treating baldness and promoting hair growth
TWI572599B (zh) * 2011-03-28 2017-03-01 Mei製藥公司 (α-經取代之芳烷胺基及雜芳烷胺基)嘧啶基及1,3,5-三基苯并咪唑,其醫藥組合物及其在治療增生性疾病之用途
HUE049175T2 (hu) * 2014-09-23 2020-09-28 Hoffmann La Roche Eljárás anti-CD79b immunkonjugátumok alkalmazására
WO2017007658A1 (en) * 2015-07-07 2017-01-12 Rigel Pharmaceuticals, Inc. A combination for immune mediated cancer treatment
KR20180042356A (ko) * 2015-08-24 2018-04-25 에피자임, 인코포레이티드 암 치료 방법
EP3487878A4 (en) * 2016-07-20 2020-03-25 University of Utah Research Foundation CD229-CAR-T CELLS AND METHOD FOR USE THEREOF
IL292938A (en) * 2016-09-19 2022-07-01 Mei Pharma Inc Combined treatment
WO2018060833A1 (en) * 2016-09-27 2018-04-05 Novartis Ag Dosage regimen for alpha-isoform selective phosphatidylinositol 3-kinase inhibitor alpelisib
WO2018082444A1 (zh) * 2016-11-02 2018-05-11 叶宝欢 吡唑并嘧啶化合物作为pi3k抑制剂及其应用
KR20200041358A (ko) * 2017-08-14 2020-04-21 메이 파마, 아이엔씨. 병용 요법

Also Published As

Publication number Publication date
CN112888441A (zh) 2021-06-01
WO2020036999A1 (en) 2020-02-20
TW202021591A (zh) 2020-06-16
KR20210043635A (ko) 2021-04-21
EP3836935A1 (en) 2021-06-23
CA3109184A1 (en) 2020-02-20
MA53236A (fr) 2021-06-23
EP3836935A4 (en) 2022-09-14
IL280726A (en) 2021-03-25
SG11202101450VA (en) 2021-03-30
MX2021001606A (es) 2021-04-19
JP2021534115A (ja) 2021-12-09
AU2019321432A1 (en) 2021-03-25
US20210299134A1 (en) 2021-09-30

Similar Documents

Publication Publication Date Title
BR112020019082A2 (pt) Terapia combinada
US9707236B2 (en) Combination methods for treating cancers
US11351176B2 (en) Combination therapy
BR112015026257B1 (pt) Uso de um composto dihidropirazino-pirazina e enzalutamida, composição farmacêutica que os compreende, e kit
BR112021002760A2 (pt) tratamento de malignidades de célula b
EP3279201A1 (en) Cdk inhibitor, eutectic crystal of mek inhibitor, and preparation method therefor
BR112021002734A2 (pt) tratamento de linfoma folicular reincidente
TW202021592A (zh) 組合療法
WO2023070120A1 (en) Ketoamides for treating malignancy

Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE A 5A ANUIDADE.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: EM VIRTUDE DO ARQUIVAMENTO PUBLICADO NA RPI 2787 DE 04-06-2024 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDO O ARQUIVAMENTO DO PEDIDO DE PATENTE, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013.