BR112020024197A2 - método para produção biocatalítica de compostos de terpeno - Google Patents

método para produção biocatalítica de compostos de terpeno Download PDF

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Publication number
BR112020024197A2
BR112020024197A2 BR112020024197-0A BR112020024197A BR112020024197A2 BR 112020024197 A2 BR112020024197 A2 BR 112020024197A2 BR 112020024197 A BR112020024197 A BR 112020024197A BR 112020024197 A2 BR112020024197 A2 BR 112020024197A2
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BR
Brazil
Prior art keywords
seq
amino acid
acid sequence
diphosphate
polypeptide
Prior art date
Application number
BR112020024197-0A
Other languages
English (en)
Portuguese (pt)
Inventor
Michel Schalk
Letizia ROCCI
Daniel Solis Escalante
Original Assignee
Firmenich S/A
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Firmenich S/A filed Critical Firmenich S/A
Publication of BR112020024197A2 publication Critical patent/BR112020024197A2/pt

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0006—Oxidoreductases (1.) acting on CH-OH groups as donors (1.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/02—Oxygen as only ring hetero atoms
    • C12P17/04—Oxygen as only ring hetero atoms containing a five-membered hetero ring, e.g. griseofulvin, vitamin C
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/02—Preparation of oxygen-containing organic compounds containing a hydroxy group
    • C12P7/04—Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/02—Preparation of oxygen-containing organic compounds containing a hydroxy group
    • C12P7/04—Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic
    • C12P7/18—Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic polyhydric
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y101/00—Oxidoreductases acting on the CH-OH group of donors (1.1)
    • C12Y101/01—Oxidoreductases acting on the CH-OH group of donors (1.1) with NAD+ or NADP+ as acceptor (1.1.1)
    • C12Y101/01001—Alcohol dehydrogenase (1.1.1.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y301/00—Hydrolases acting on ester bonds (3.1)
    • C12Y301/07—Diphosphoric monoester hydrolases (3.1.7)
    • C12Y301/07003—Monoterpenyl-diphosphatase (3.1.7.3)

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
BR112020024197-0A 2018-07-10 2019-07-10 método para produção biocatalítica de compostos de terpeno BR112020024197A2 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP18182783 2018-07-10
EP18182783.3 2018-07-10
PCT/EP2019/068609 WO2020011883A1 (en) 2018-07-10 2019-07-10 Method for biocatalytic production of terpene compounds

Publications (1)

Publication Number Publication Date
BR112020024197A2 true BR112020024197A2 (pt) 2021-02-17

Family

ID=62916485

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112020024197-0A BR112020024197A2 (pt) 2018-07-10 2019-07-10 método para produção biocatalítica de compostos de terpeno

Country Status (7)

Country Link
US (1) US11214775B2 (https=)
EP (1) EP3821023A1 (https=)
JP (2) JP7406511B2 (https=)
CN (1) CN112334581B (https=)
BR (1) BR112020024197A2 (https=)
MX (1) MX2020012933A (https=)
WO (1) WO2020011883A1 (https=)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11214775B2 (en) * 2018-07-10 2022-01-04 Firmenich Sa Method for biocatalytic production of terpene compounds
US12378579B2 (en) 2020-03-06 2025-08-05 Board Of Trustees Of Michigan State University Method to produce the anti-microbial diterpenoid leubethanol and related serrulatane-type diterpenes
EP4370671A4 (en) * 2021-07-16 2025-08-27 Amyris Inc NEW ENZYMES FOR THE PRODUCTION OF E-COPALOL
WO2024256473A2 (en) 2023-06-12 2024-12-19 Firmenich Sa Polypeptides for preparing terpenoid compounds
WO2026041452A2 (en) 2024-08-19 2026-02-26 Firmenich Sa Method for production of terpene compounds
WO2026068770A2 (en) 2024-09-30 2026-04-02 Firmenich Sa Preparation of terpenoid compounds

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6303654B1 (en) * 1998-03-12 2001-10-16 Wisconsin Alumni Research Foundation Acyclic monoterpenoid derivatives
DE19931847A1 (de) 1999-07-09 2001-01-11 Basf Ag Immobilisierte Lipase
DE10019380A1 (de) 2000-04-19 2001-10-25 Basf Ag Verfahren zur Herstellung von kovalent gebundenen biologisch aktiven Stoffen an Polyurethanschaumstoffen sowie Verwendung der geträgerten Polyurethanschaumstoffe für chirale Synthesen
EP2238256B1 (en) 2008-01-29 2015-10-14 Firmenich S.A. Method for producing sclareol
GB201601249D0 (en) * 2016-01-22 2016-03-09 Firmenich & Cie Production of manool
KR102636404B1 (ko) 2016-06-15 2024-02-13 경상국립대학교산학협력단 터펜 알코올 또는 그 유도체의 제조 방법
CN107119001B (zh) 2017-04-26 2019-07-19 福建师范大学 基因工程化类球红细菌及其制备方法和法尼醇的生产方法
US11214775B2 (en) 2018-07-10 2022-01-04 Firmenich Sa Method for biocatalytic production of terpene compounds

Also Published As

Publication number Publication date
WO2020011883A1 (en) 2020-01-16
JP2021524261A (ja) 2021-09-13
JP7406511B2 (ja) 2023-12-27
JP2024029002A (ja) 2024-03-05
CN112334581B (zh) 2024-11-12
US20210222138A1 (en) 2021-07-22
JP7717142B2 (ja) 2025-08-01
EP3821023A1 (en) 2021-05-19
CN112334581A (zh) 2021-02-05
MX2020012933A (es) 2021-02-15
US11214775B2 (en) 2022-01-04

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Legal Events

Date Code Title Description
B350 Update of information on the portal [chapter 15.35 patent gazette]
B06W Patent application suspended after preliminary examination (for patents with searches from other patent authorities) chapter 6.23 patent gazette]