BR112020012273A2 - métodos e composições para induzir uma resposta imune contra o vírus da hepatite b (hbv) - Google Patents
métodos e composições para induzir uma resposta imune contra o vírus da hepatite b (hbv) Download PDFInfo
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- C12N15/86—Viral vectors
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- A61K39/12—Viral antigens
- A61K39/29—Hepatitis virus
- A61K39/292—Serum hepatitis virus, hepatitis B virus, e.g. Australia antigen
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- A—HUMAN NECESSITIES
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- A61K39/12—Viral antigens
- A61K39/29—Hepatitis virus
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- A—HUMAN NECESSITIES
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- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
- C07K14/01—DNA viruses
- C07K14/02—Hepadnaviridae, e.g. hepatitis B virus
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- C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
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- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
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- C12N2710/24143—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
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- C—CHEMISTRY; METALLURGY
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- C12N2730/00—Reverse transcribing DNA viruses
- C12N2730/00011—Details
- C12N2730/10011—Hepadnaviridae
- C12N2730/10111—Orthohepadnavirus, e.g. hepatitis B virus
- C12N2730/10131—Uses of virus other than therapeutic or vaccine, e.g. disinfectant
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US201762607439P | 2017-12-19 | 2017-12-19 | |
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WOPCT/IB2017/058148 | 2017-12-19 | ||
PCT/IB2018/060257 WO2019123250A1 (en) | 2017-12-19 | 2018-12-18 | Methods and compositions for inducing an immune response against hepatitis b virus (hbv) |
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BR112020012273A2 true BR112020012273A2 (pt) | 2020-11-24 |
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EP (1) | EP3727446A1 (ja) |
JP (1) | JP2021506300A (ja) |
KR (1) | KR20200100745A (ja) |
CN (1) | CN111741766A (ja) |
AU (1) | AU2018389786A1 (ja) |
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CA (1) | CA3086325A1 (ja) |
IL (1) | IL275423A (ja) |
MA (1) | MA51312A (ja) |
MX (1) | MX2020006471A (ja) |
SG (1) | SG11202005710YA (ja) |
WO (1) | WO2019123250A1 (ja) |
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EA202091516A1 (ru) | 2017-12-19 | 2020-11-03 | Янссен Сайенсиз Айрлэнд Анлимитед Компани | Способы и композиции для индукции иммунного ответа против вируса гепатита b (hbv) |
EA202091517A1 (ru) | 2017-12-19 | 2020-11-03 | Янссен Сайенсиз Айрлэнд Анлимитед Компани | Способы и устройство для доставки вакцин против вируса гепатита b (hbv) |
EA202091513A1 (ru) | 2017-12-19 | 2020-09-09 | Янссен Сайенсиз Айрлэнд Анлимитед Компани | Вакцины против вируса гепатита b (hbv) и их применение |
WO2020255055A1 (en) * | 2019-06-20 | 2020-12-24 | Janssen Sciences Ireland Unlimited Company | Self-replicating rna molecules for hepatitis b virus (hbv) vaccines and uses thereof |
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CA92121A (en) | 1904-11-07 | 1905-03-14 | William Waid Paddock | Pressure filter |
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CA2285056C (en) | 1997-04-03 | 2004-12-14 | Iacob Mathiesen | Method for introducing pharmaceutical drugs and nucleic acids into skeletal muscle |
US6261281B1 (en) | 1997-04-03 | 2001-07-17 | Electrofect As | Method for genetic immunization and introduction of molecules into skeletal muscle and immune cells |
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IL133710A0 (en) | 1997-06-30 | 2001-04-30 | Rhone Poulence Rorer S A | Improved method for transferring nucleic acid into the striped muscle and combination thereof |
WO2000002621A1 (en) | 1998-07-13 | 2000-01-20 | Genetronics, Inc. | Skin and muscle-targeted gene therapy by pulsed electrical field |
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AU777041B2 (en) | 1999-05-17 | 2004-09-30 | Crucell Holland B.V. | Adenovirus derived gene delivery vehicles comprising at least one element of adenovirus type 35 |
US6913922B1 (en) | 1999-05-18 | 2005-07-05 | Crucell Holland B.V. | Serotype of adenovirus and uses thereof |
NZ524661A (en) | 2000-11-23 | 2005-03-24 | Bavarian Nordic As | Modified vaccinia ankara virus variant |
AU2002356690B2 (en) | 2001-12-04 | 2008-07-24 | Bavarian Nordic A/S | Flavivirus NS1 subunit vaccine |
US7245963B2 (en) | 2002-03-07 | 2007-07-17 | Advisys, Inc. | Electrode assembly for constant-current electroporation and use |
US8209006B2 (en) | 2002-03-07 | 2012-06-26 | Vgx Pharmaceuticals, Inc. | Constant current electroporation device and methods of use |
US6912417B1 (en) | 2002-04-05 | 2005-06-28 | Ichor Medical Systmes, Inc. | Method and apparatus for delivery of therapeutic agents |
PL208588B1 (pl) | 2002-04-25 | 2011-05-31 | Crucell Holland Bv | Rekombinowane adenowirusy, wyizolowane kwasy nukleinowe, komórki pakujące oraz sposoby zwiększania stabilności i/lub pojemności upakowania rekombinowanego adenowirusa |
JP4495587B2 (ja) | 2002-04-25 | 2010-07-07 | クルセル ホランド ベー ヴェー | 組換えアデノウイルスベクターおよびその使用 |
US7328064B2 (en) | 2002-07-04 | 2008-02-05 | Inovio As | Electroporation device and injection apparatus |
CN107723298A (zh) | 2004-01-23 | 2018-02-23 | Msd意大利有限公司 | 黑猩猩腺病毒疫苗载运体 |
CN102886101B (zh) | 2004-03-08 | 2015-10-28 | 艾科医疗系统公司 | 改进的治疗剂电介导输送设备 |
CN101248173A (zh) * | 2005-04-08 | 2008-08-20 | 墨尔本保健公司 | 对于抗病毒核苷试剂具有抗性的乙型肝炎病毒变异体及其应用 |
US20100143302A1 (en) | 2006-03-16 | 2010-06-10 | Crucell Holland B.V. | Recombinant Adenoviruses Based on Serotype 26 and 48, and Use Thereof |
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WO2009056535A2 (en) * | 2007-10-29 | 2009-05-07 | Genimmune N.V. | Methods and kits for inducing a ctl response using a prime boost regimen |
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WO2010085984A1 (en) | 2009-02-02 | 2010-08-05 | Okairos Ag | Simian adenovirus nucleic acid- and amino acid-sequences, vectors containing same, and uses thereof |
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WO2012082918A1 (en) | 2010-12-14 | 2012-06-21 | The Goverment Of The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | Adenovirus serotype 26 and serotype 35 filovirus vaccines |
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KR20200087880A (ko) | 2012-10-28 | 2020-07-21 | 버베리안 노딕 에이/에스 | 강력한 t-세포 및 항체 반응을 위한 pr13.5 프로모터 |
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WO2019123250A1 (en) | 2019-06-27 |
EP3727446A1 (en) | 2020-10-28 |
KR20200100745A (ko) | 2020-08-26 |
MA51312A (fr) | 2020-10-28 |
MX2020006471A (es) | 2020-09-22 |
JP2021506300A (ja) | 2021-02-22 |
CA3086325A1 (en) | 2019-06-27 |
SG11202005710YA (en) | 2020-07-29 |
CN111741766A (zh) | 2020-10-02 |
IL275423A (en) | 2020-08-31 |
AU2018389786A1 (en) | 2020-06-18 |
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