BR112020005845B8 - Método de produção para células bacterianas - Google Patents

Método de produção para células bacterianas

Info

Publication number
BR112020005845B8
BR112020005845B8 BR112020005845A BR112020005845A BR112020005845B8 BR 112020005845 B8 BR112020005845 B8 BR 112020005845B8 BR 112020005845 A BR112020005845 A BR 112020005845A BR 112020005845 A BR112020005845 A BR 112020005845A BR 112020005845 B8 BR112020005845 B8 BR 112020005845B8
Authority
BR
Brazil
Prior art keywords
bacterial cells
production method
antibiotic
stage
bacteria
Prior art date
Application number
BR112020005845A
Other languages
English (en)
Other versions
BR112020005845B1 (pt
BR112020005845A2 (pt
Inventor
Morishita Yasuyuki
Original Assignee
Idemitsu Kosan Co
Sds Biotech Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Idemitsu Kosan Co, Sds Biotech Corp filed Critical Idemitsu Kosan Co
Publication of BR112020005845A2 publication Critical patent/BR112020005845A2/pt
Publication of BR112020005845B1 publication Critical patent/BR112020005845B1/pt
Publication of BR112020005845B8 publication Critical patent/BR112020005845B8/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C12N1/205—Bacterial isolates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/07—Bacillus

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Wood Science & Technology (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Virology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

A presente invenção provê um método para produzir células bacterianas, que compreende, em um processo de cultura líquida de múltiplos estágios para bactérias, cultivar uma bactéria em um meio líquido contendo um antibiótico em um estágio anterior ao estágio final e depois diminuindo a concentração do antibiótico no estágio final até um nível mais baixo do que aquele no estágio anterior. Consequentemente, as células bacterianas podem ser produzidas com boa produtividade enquanto suprimem o aparecimento de variantes que formam colônias anormais entre as bactérias obtidas depois da cultura.
BR112020005845A 2017-09-25 2018-09-25 Método de produção para células bacterianas BR112020005845B8 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2017183587A JP6996680B2 (ja) 2017-09-25 2017-09-25 細菌菌体の製造方法
JP2017-183587 2017-09-25
PCT/JP2018/035361 WO2019059396A1 (ja) 2017-09-25 2018-09-25 細菌菌体の製造方法

Publications (3)

Publication Number Publication Date
BR112020005845A2 BR112020005845A2 (pt) 2020-09-29
BR112020005845B1 BR112020005845B1 (pt) 2022-05-17
BR112020005845B8 true BR112020005845B8 (pt) 2022-12-13

Family

ID=65810446

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112020005845A BR112020005845B8 (pt) 2017-09-25 2018-09-25 Método de produção para células bacterianas

Country Status (10)

Country Link
US (1) US11377632B2 (pt)
EP (1) EP3690025A4 (pt)
JP (1) JP6996680B2 (pt)
KR (1) KR102490149B1 (pt)
CN (1) CN111133098B (pt)
BR (1) BR112020005845B8 (pt)
CA (1) CA3076989C (pt)
MX (1) MX2020003295A (pt)
TW (1) TWI757549B (pt)
WO (1) WO2019059396A1 (pt)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP6996680B2 (ja) * 2017-09-25 2022-01-17 出光興産株式会社 細菌菌体の製造方法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1298668A (en) * 1969-03-25 1972-12-06 Rolland Sa A Process for obtaining and preserving stable bacterial variants
RU2213780C2 (ru) * 2001-11-13 2003-10-10 Леви Моисей Иосифович Способ определения бактериостатического и бактерицидного действия антибиотика
US7455840B2 (en) * 2003-11-19 2008-11-25 The Scripps Research Institute Compositions and methods to reduce mutagenesis
BR112016008438B1 (pt) * 2013-10-17 2022-08-23 Idemitsu Kosan Co., Ltd. Método de promoção de crescimento de uma planta, método para controlar uma doença de plantas, método de controle de um nematoide, método de cultivo de uma planta, uso de uma célula bacteriana ou um produto de cultura de um micro-organismo que é uma cepa de bacillus sp. itb105 (nite bp-01727)
ES2776823T3 (es) * 2015-04-09 2020-08-03 Idemitsu Kosan Co Método de esporulación de una bacteria de Bacillus
CN105296409B (zh) * 2015-07-14 2018-11-27 西安交通大学 一株用于生产固定化碱性果胶酶纳米微球的工程菌及其构建方法与应用
JP7019584B2 (ja) * 2016-10-07 2022-02-15 出光興産株式会社 芽胞形成細菌の培養方法および有用物質の製造方法
JP6996680B2 (ja) * 2017-09-25 2022-01-17 出光興産株式会社 細菌菌体の製造方法

Also Published As

Publication number Publication date
BR112020005845B1 (pt) 2022-05-17
WO2019059396A1 (ja) 2019-03-28
US11377632B2 (en) 2022-07-05
TWI757549B (zh) 2022-03-11
BR112020005845A2 (pt) 2020-09-29
CA3076989A1 (en) 2019-03-28
TW201920650A (zh) 2019-06-01
MX2020003295A (es) 2022-03-22
JP2019058083A (ja) 2019-04-18
JP6996680B2 (ja) 2022-01-17
CN111133098A (zh) 2020-05-08
CA3076989C (en) 2023-01-03
CN111133098B (zh) 2023-06-30
US20200277564A1 (en) 2020-09-03
EP3690025A1 (en) 2020-08-05
KR102490149B1 (ko) 2023-01-18
KR20200057018A (ko) 2020-05-25
EP3690025A4 (en) 2021-06-09

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Legal Events

Date Code Title Description
B350 Update of information on the portal [chapter 15.35 patent gazette]
B09A Decision: intention to grant [chapter 9.1 patent gazette]
B16A Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]

Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 25/09/2018, OBSERVADAS AS CONDICOES LEGAIS

B25G Requested change of headquarter approved

Owner name: SDS BIOTECH K.K. (JP)

B25A Requested transfer of rights approved

Owner name: SDS BIOTECH K.K. (JP)