BR112019025447A2 - Dispositivo de tratamento de reação - Google Patents
Dispositivo de tratamento de reaçãoInfo
- Publication number
- BR112019025447A2 BR112019025447A2 BR112019025447-1A BR112019025447A BR112019025447A2 BR 112019025447 A2 BR112019025447 A2 BR 112019025447A2 BR 112019025447 A BR112019025447 A BR 112019025447A BR 112019025447 A2 BR112019025447 A2 BR 112019025447A2
- Authority
- BR
- Brazil
- Prior art keywords
- sample
- temperature region
- channel
- low temperature
- treatment device
- Prior art date
Links
Classifications
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J19/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J19/0093—Microreactors, e.g. miniaturised or microfabricated reactors
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
- B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
- B01L3/502715—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by interfacing components, e.g. fluidic, electrical, optical or mechanical interfaces
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/508—Containers for the purpose of retaining a material to be analysed, e.g. test tubes rigid containers not provided for above
- B01L3/5085—Containers for the purpose of retaining a material to be analysed, e.g. test tubes rigid containers not provided for above for multiple samples, e.g. microtitration plates
- B01L3/50851—Containers for the purpose of retaining a material to be analysed, e.g. test tubes rigid containers not provided for above for multiple samples, e.g. microtitration plates specially adapted for heating or cooling samples
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L7/00—Heating or cooling apparatus; Heat insulating devices
- B01L7/52—Heating or cooling apparatus; Heat insulating devices with provision for submitting samples to a predetermined sequence of different temperatures, e.g. for treating nucleic acid samples
- B01L7/525—Heating or cooling apparatus; Heat insulating devices with provision for submitting samples to a predetermined sequence of different temperatures, e.g. for treating nucleic acid samples with physical movement of samples between temperature zones
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M1/00—Apparatus for enzymology or microbiology
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M1/00—Apparatus for enzymology or microbiology
- C12M1/36—Apparatus for enzymology or microbiology including condition or time responsive control, e.g. automatically controlled fermentors
- C12M1/38—Temperature-responsive control
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6806—Preparing nucleic acids for analysis, e.g. for polymerase chain reaction [PCR] assay
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6844—Nucleic acid amplification reactions
- C12Q1/686—Polymerase chain reaction [PCR]
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/01—Arrangements or apparatus for facilitating the optical investigation
- G01N21/13—Moving of cuvettes or solid samples to or from the investigating station
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/64—Fluorescence; Phosphorescence
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/08—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a stream of discrete samples flowing along a tube system, e.g. flow injection analysis
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N37/00—Details not covered by any other group of this subclass
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00781—Aspects relating to microreactors
- B01J2219/00873—Heat exchange
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00781—Aspects relating to microreactors
- B01J2219/0095—Control aspects
- B01J2219/00986—Microprocessor
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
- B01L2200/14—Process control and prevention of errors
- B01L2200/143—Quality control, feedback systems
- B01L2200/147—Employing temperature sensors
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/08—Geometry, shape and general structure
- B01L2300/0861—Configuration of multiple channels and/or chambers in a single devices
- B01L2300/0883—Serpentine channels
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biochemistry (AREA)
- Analytical Chemistry (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biotechnology (AREA)
- Physics & Mathematics (AREA)
- Immunology (AREA)
- Microbiology (AREA)
- Genetics & Genomics (AREA)
- General Engineering & Computer Science (AREA)
- Pathology (AREA)
- General Physics & Mathematics (AREA)
- Clinical Laboratory Science (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Hematology (AREA)
- Sustainable Development (AREA)
- Medicinal Chemistry (AREA)
- Biomedical Technology (AREA)
- Biophysics (AREA)
- Dispersion Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Automatic Analysis And Handling Materials Therefor (AREA)
- Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
Abstract
a presente invenção refere-se a um processador de reação (30) dotado de um vaso de processamento de reação (10) em que um canal (12) é formado, um sistema de alimentação de líquido (37), um sistema de controle de temperatura (32) para fornecer uma região de alta temperatura e uma região de baixa temperatura ao canal (12), e um detector de fluorescência (50) para detectar a amostra (20) que passa através de uma região de detecção de fluorescência do canal (12), e uma cpu (36) para controlar o sistema de alimentação de líquido (37) com base em um sinal que é detectado. uma posição de parada-alvo x[l]0(n+1) da amostra na região de baixa temperatura em um (n+1)ésimo ciclo é corrigida a partir da posição de parada-alvo x[l]0(n) da amostra na região de baixa temperatura no n-ésimo ciclo com base no resultado de controle de parada na amostra (20) no n-ésimo ciclo.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2017111817 | 2017-06-06 | ||
JP2017-111817 | 2017-06-06 | ||
PCT/JP2018/020471 WO2018225577A1 (ja) | 2017-06-06 | 2018-05-29 | 反応処理装置 |
Publications (1)
Publication Number | Publication Date |
---|---|
BR112019025447A2 true BR112019025447A2 (pt) | 2020-06-16 |
Family
ID=64566231
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR112019025447-1A BR112019025447A2 (pt) | 2017-06-06 | 2018-05-29 | Dispositivo de tratamento de reação |
Country Status (7)
Country | Link |
---|---|
US (1) | US11541394B2 (pt) |
EP (1) | EP3636739B1 (pt) |
JP (2) | JP6507323B1 (pt) |
CN (1) | CN110603315B (pt) |
BR (1) | BR112019025447A2 (pt) |
RU (1) | RU2750599C1 (pt) |
WO (1) | WO2018225577A1 (pt) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2020129116A1 (ja) * | 2018-12-17 | 2020-06-25 | 日本板硝子株式会社 | 反応処理装置、反応処理容器および反応処理方法 |
JPWO2020189581A1 (pt) * | 2019-03-15 | 2020-09-24 | ||
WO2022153999A1 (ja) * | 2021-01-14 | 2022-07-21 | 杏林製薬株式会社 | 反応処理容器、及び反応処理装置 |
Family Cites Families (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE58907327D1 (de) | 1988-06-01 | 1994-05-05 | Deutsche Aerospace | Vorrichtung mit Träger besonderer Struktur zur Aufnahme, Untersuchung und Behandlung von Proben. |
US5270183A (en) * | 1991-02-08 | 1993-12-14 | Beckman Research Institute Of The City Of Hope | Device and method for the automated cycling of solutions between two or more temperatures |
JPWO2003057875A1 (ja) * | 2002-01-08 | 2005-05-19 | 独立行政法人科学技術振興機構 | 静電搬送によるpcr方法、静電搬送活用のハイブリダイゼーション方法及びそれらの装置 |
GB2433259A (en) * | 2005-11-30 | 2007-06-20 | Deltadot Ltd | Nucleic acid amplification method and microfluidic apparatus therefore |
JP5178149B2 (ja) * | 2007-10-31 | 2013-04-10 | キヤノン株式会社 | 標的核酸のリアルタイムpcr方法及びその装置 |
JP5303983B2 (ja) * | 2008-03-26 | 2013-10-02 | 株式会社島津製作所 | 反応処理方法及び反応処理装置 |
CA2824404C (en) * | 2011-01-06 | 2023-01-03 | Meso Scale Technologies, Llc | Assay cartridges for pcr analysis and methods of use thereof |
JP2013055921A (ja) * | 2011-09-09 | 2013-03-28 | National Institute Of Advanced Industrial Science & Technology | 核酸増幅方法 |
JP2015053893A (ja) * | 2013-09-11 | 2015-03-23 | 公益財団法人神奈川科学技術アカデミー | 高速遺伝子増幅検出装置 |
KR101618113B1 (ko) * | 2014-02-10 | 2016-05-09 | 나노바이오시스 주식회사 | 일 방향 슬라이딩 구동 수단을 구비하는 pcr 장치 및 이를 이용하는 pcr 방법 |
CN106536704B (zh) * | 2014-07-08 | 2020-03-06 | 国立研究开发法人产业技术综合研究所 | 核酸扩增装置、核酸扩增方法以及核酸扩增用芯片 |
EP3460038B1 (en) * | 2016-05-18 | 2024-04-10 | Go!Foton, Inc. | Reaction treatment device, and method for controlling reaction treatment device |
-
2018
- 2018-05-29 WO PCT/JP2018/020471 patent/WO2018225577A1/ja unknown
- 2018-05-29 JP JP2018550490A patent/JP6507323B1/ja active Active
- 2018-05-29 EP EP18813162.7A patent/EP3636739B1/en active Active
- 2018-05-29 BR BR112019025447-1A patent/BR112019025447A2/pt not_active Application Discontinuation
- 2018-05-29 RU RU2019143829A patent/RU2750599C1/ru active
- 2018-05-29 CN CN201880030198.4A patent/CN110603315B/zh active Active
-
2019
- 2019-04-01 JP JP2019069668A patent/JP6977936B2/ja active Active
- 2019-11-19 US US16/687,804 patent/US11541394B2/en active Active
Also Published As
Publication number | Publication date |
---|---|
US20200086313A1 (en) | 2020-03-19 |
JP6977936B2 (ja) | 2021-12-08 |
CN110603315B (zh) | 2022-08-09 |
JPWO2018225577A1 (ja) | 2019-06-27 |
EP3636739A1 (en) | 2020-04-15 |
RU2750599C1 (ru) | 2021-06-29 |
EP3636739C0 (en) | 2023-11-15 |
JP6507323B1 (ja) | 2019-04-24 |
EP3636739B1 (en) | 2023-11-15 |
JP2019134710A (ja) | 2019-08-15 |
CN110603315A (zh) | 2019-12-20 |
US11541394B2 (en) | 2023-01-03 |
EP3636739A4 (en) | 2021-03-03 |
WO2018225577A1 (ja) | 2018-12-13 |
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B350 | Update of information on the portal [chapter 15.35 patent gazette] | ||
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B11B | Dismissal acc. art. 36, par 1 of ipl - no reply within 90 days to fullfil the necessary requirements |