BR112019014707A2 - peptídeo mimético apoc-ii isolado, composição farmacêutica, e, métodos para tratar hipertrigliceridemia e para fabricar o peptídeo. - Google Patents
peptídeo mimético apoc-ii isolado, composição farmacêutica, e, métodos para tratar hipertrigliceridemia e para fabricar o peptídeo. Download PDFInfo
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- BR112019014707A2 BR112019014707A2 BR112019014707A BR112019014707A BR112019014707A2 BR 112019014707 A2 BR112019014707 A2 BR 112019014707A2 BR 112019014707 A BR112019014707 A BR 112019014707A BR 112019014707 A BR112019014707 A BR 112019014707A BR 112019014707 A2 BR112019014707 A2 BR 112019014707A2
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- apoc
- peptide according
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- peptide
- amino acid
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Classifications
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- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
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- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/1703—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- A61K38/1709—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
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- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/1703—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- A61K38/1709—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- A61K38/1722—Plasma globulins, lactoglobulins
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- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/52—Constant or Fc region; Isotype
- C07K2317/53—Hinge
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/20—Fusion polypeptide containing a tag with affinity for a non-protein ligand
- C07K2319/21—Fusion polypeptide containing a tag with affinity for a non-protein ligand containing a His-tag
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/40—Fusion polypeptide containing a tag for immunodetection, or an epitope for immunisation
- C07K2319/41—Fusion polypeptide containing a tag for immunodetection, or an epitope for immunisation containing a Myc-tag
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/40—Fusion polypeptide containing a tag for immunodetection, or an epitope for immunisation
- C07K2319/42—Fusion polypeptide containing a tag for immunodetection, or an epitope for immunisation containing a HA(hemagglutinin)-tag
Landscapes
- Health & Medical Sciences (AREA)
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- Chemical & Material Sciences (AREA)
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- Animal Behavior & Ethology (AREA)
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- Cardiology (AREA)
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- Endocrinology (AREA)
- Emergency Medicine (AREA)
- Child & Adolescent Psychology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201762448358P | 2017-01-19 | 2017-01-19 | |
| US201762476535P | 2017-03-24 | 2017-03-24 | |
| US201762476531P | 2017-03-24 | 2017-03-24 | |
| PCT/US2018/014532 WO2018136803A1 (en) | 2017-01-19 | 2018-01-19 | Apoc-ii mimetic peptides |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR112019014707A2 true BR112019014707A2 (pt) | 2020-04-07 |
Family
ID=62908746
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR112019014707A BR112019014707A2 (pt) | 2017-01-19 | 2018-01-19 | peptídeo mimético apoc-ii isolado, composição farmacêutica, e, métodos para tratar hipertrigliceridemia e para fabricar o peptídeo. |
Country Status (14)
| Country | Link |
|---|---|
| US (2) | US11136372B2 (https=) |
| EP (1) | EP3571216A4 (https=) |
| JP (2) | JP7353973B2 (https=) |
| KR (1) | KR102700862B1 (https=) |
| CN (1) | CN110831957B (https=) |
| AU (1) | AU2018210404B2 (https=) |
| BR (1) | BR112019014707A2 (https=) |
| CA (1) | CA3050106A1 (https=) |
| IL (2) | IL268093B2 (https=) |
| MX (1) | MX2019008529A (https=) |
| NZ (1) | NZ755599A (https=) |
| SG (2) | SG10201911974UA (https=) |
| TW (2) | TWI788323B (https=) |
| WO (1) | WO2018136803A1 (https=) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MX2019008529A (es) | 2017-01-19 | 2020-02-07 | Us Health | Peptidos mimeticos de apolipoproteina c-ii (apoc-ii). |
| US20240309065A1 (en) * | 2021-06-23 | 2024-09-19 | The United States Of America, As Represented By The Secretary, Dept. Of Health And Human Services | Short apoc-ii mimetic peptides and methods of use |
| IL316418A (en) * | 2022-05-05 | 2024-12-01 | Us Health | Short apolipoprotein E mimetic peptides and methods of use |
| EP4565251A1 (en) * | 2022-08-07 | 2025-06-11 | Protean Bio, Inc. | Peptides for beta-cell survival and insulin production |
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| US4179337A (en) | 1973-07-20 | 1979-12-18 | Davis Frank F | Non-immunogenic polypeptides |
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| US4496689A (en) | 1983-12-27 | 1985-01-29 | Miles Laboratories, Inc. | Covalently attached complex of alpha-1-proteinase inhibitor with a water soluble polymer |
| DE3675588D1 (de) | 1985-06-19 | 1990-12-20 | Ajinomoto Kk | Haemoglobin, das an ein poly(alkenylenoxid) gebunden ist. |
| US4791192A (en) | 1986-06-26 | 1988-12-13 | Takeda Chemical Industries, Ltd. | Chemically modified protein with polyethyleneglycol |
| US6156727A (en) * | 1996-09-05 | 2000-12-05 | Uab Research Foundation | Anti-atherosclerotic peptides and a transgenic mouse model of antherosclerosis |
| AU2002362612B2 (en) | 2001-09-28 | 2007-11-15 | Cedars-Sinai Medical Center | Prevention and treatment of restenosis by local administration of drug |
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| JP2007504285A (ja) * | 2003-01-17 | 2007-03-01 | メルク エンド カムパニー インコーポレーテッド | Ｎ−シクロヘキシルアミノカルボニルベンゼンスルホンアミド誘導体 |
| WO2005058938A2 (en) * | 2003-12-15 | 2005-06-30 | The Regents Of The University Of California | Helical synthetic peptides that stimulate cellular cholesterol efflux |
| JPWO2005080348A1 (ja) * | 2004-02-19 | 2007-08-02 | 萬有製薬株式会社 | 新規スルホンアミド誘導体 |
| CN101076541A (zh) | 2004-07-16 | 2007-11-21 | 塔夫茨大学信托人 | 载脂蛋白a1模拟物及其用途 |
| US8575307B2 (en) * | 2005-06-29 | 2013-11-05 | Hadasit Medical Research Services & Development Ltd. | Protein kinase C inhibitors for prevention of insulin resistance and type 2 diabetes |
| WO2008039843A2 (en) * | 2006-09-26 | 2008-04-03 | Lipid Sciences, Inc. | Novel peptides that promote lipid efflux |
| WO2009097584A1 (en) | 2008-01-30 | 2009-08-06 | Proteogenix, Inc. | Maternal serum biomarkers for detection of pre-eclampsia |
| WO2009129263A1 (en) * | 2008-04-15 | 2009-10-22 | The Government Of The Usa As Represented By The Secretary Of The Department Of Health & Human Serv. | Peptides promoting lipid efflux via abca1 and activating a lipoprotein lipase |
| WO2011040654A1 (ko) | 2009-09-30 | 2011-04-07 | 서울대학교산학협력단 | 아포리포프로테인 에이１ 모방 펩타이드，및 이를 포함하는 고지혈증 및 이와 관련된 질환 치료제 |
| BR112015010276A2 (pt) * | 2012-11-06 | 2019-10-15 | Hoffmann La Roche | peptídeos miméticos |
| MX2019008529A (es) | 2017-01-19 | 2020-02-07 | Us Health | Peptidos mimeticos de apolipoproteina c-ii (apoc-ii). |
| EA201991491A1 (ru) | 2017-03-24 | 2019-12-30 | Дзе Юнайтед Стейтс Оф Америка, Эз Репрезентед Бай Дзе Секретари, Департмент Оф Хелс Энд Хьюман Сервисис | Миметические пептиды apoc-ii |
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| US20210324043A1 (en) | 2021-10-21 |
| IL268093B2 (en) | 2024-07-01 |
| EP3571216A1 (en) | 2019-11-27 |
| IL268093B1 (en) | 2024-03-01 |
| US20200140522A1 (en) | 2020-05-07 |
| CN110831957A (zh) | 2020-02-21 |
| EP3571216A4 (en) | 2020-11-04 |
| TW202130652A (zh) | 2021-08-16 |
| SG10201911974UA (en) | 2020-02-27 |
| AU2018210404B2 (en) | 2022-01-27 |
| CA3050106A1 (en) | 2018-07-26 |
| JP2023116739A (ja) | 2023-08-22 |
| TW201835097A (zh) | 2018-10-01 |
| KR102700862B1 (ko) | 2024-08-30 |
| WO2018136803A8 (en) | 2019-08-01 |
| SG11201906422VA (en) | 2019-08-27 |
| IL279831A (en) | 2021-03-01 |
| TWI788323B (zh) | 2023-01-01 |
| US11136372B2 (en) | 2021-10-05 |
| CN110831957B (zh) | 2024-02-09 |
| JP2020511425A (ja) | 2020-04-16 |
| NZ755599A (en) | 2022-12-23 |
| MX2019008529A (es) | 2020-02-07 |
| IL268093A (en) | 2019-09-26 |
| JP7353973B2 (ja) | 2023-10-02 |
| KR20190121305A (ko) | 2019-10-25 |
| AU2018210404A1 (en) | 2019-08-08 |
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