BR112019005965A2 - composição compreendendo uma molécula bioativa - Google Patents

composição compreendendo uma molécula bioativa

Info

Publication number
BR112019005965A2
BR112019005965A2 BR112019005965A BR112019005965A BR112019005965A2 BR 112019005965 A2 BR112019005965 A2 BR 112019005965A2 BR 112019005965 A BR112019005965 A BR 112019005965A BR 112019005965 A BR112019005965 A BR 112019005965A BR 112019005965 A2 BR112019005965 A2 BR 112019005965A2
Authority
BR
Brazil
Prior art keywords
composition
bioactive molecule
acid
base
solution
Prior art date
Application number
BR112019005965A
Other languages
English (en)
Other versions
BR112019005965B1 (pt
Inventor
Antonius Maria Lith Van Wilhelmus
Original Assignee
Eucaryo Beheer B V
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eucaryo Beheer B V filed Critical Eucaryo Beheer B V
Publication of BR112019005965A2 publication Critical patent/BR112019005965A2/pt
Publication of BR112019005965B1 publication Critical patent/BR112019005965B1/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/92—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one or more halogen atoms as ring hetero atoms
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N25/00—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests
    • A01N25/02—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests containing liquids as carriers, diluents or solvents
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/02—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one or more oxygen or sulfur atoms as the only ring hetero atoms
    • A01N43/04—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one or more oxygen or sulfur atoms as the only ring hetero atoms with one hetero atom
    • A01N43/06—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one or more oxygen or sulfur atoms as the only ring hetero atoms with one hetero atom five-membered rings
    • A01N43/12—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one or more oxygen or sulfur atoms as the only ring hetero atoms with one hetero atom five-membered rings condensed with a carbocyclic ring
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/90—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having two or more relevant hetero rings, condensed among themselves or with a common carbocyclic ring system
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N45/00—Biocides, pest repellants or attractants, or plant growth regulators, containing compounds having three or more carbocyclic rings condensed among themselves, at least one ring not being a six-membered ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/191—Carboxylic acids, e.g. valproic acid having two or more hydroxy groups, e.g. gluconic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Plant Pathology (AREA)
  • Dentistry (AREA)
  • Environmental Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Agronomy & Crop Science (AREA)
  • Pest Control & Pesticides (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Toxicology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Communicable Diseases (AREA)
  • Molecular Biology (AREA)
  • Organic Chemistry (AREA)
  • Oncology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Fertilizers (AREA)

Abstract

a invenção refere-se a um processo para a preparação de uma composição que compreende uma molécula bioativa compreendendo as etapas de a. dissolver uma molécula bioativa que possui pelo menos um grupo de ácido com uma base no ph = 11 para obter uma solução a, b. neutralizar a solução a com um ácido para obter a composição que compreende uma molécula bioativa tendo um ph entre 6 e 9, em que o peg é adicionado antes da etapa de neutralização no caso da base e/ou do ácido ser um composto inorgânico, e a uma composição que compreende uma concentração elevada de natamicina.
BR112019005965-2A 2016-09-28 2017-09-28 Composição compreendendo uma molécula bioativa, seu processo de preparação, produto agrícola ou alimentício e seu método de tratamento BR112019005965B1 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
NL2017545A NL2017545B1 (en) 2016-09-28 2016-09-28 Composition comprising a bioactive molecule
NL2017545 2016-09-28
PCT/EP2017/074606 WO2018060321A1 (en) 2016-09-28 2017-09-28 Composition comprising a bioactive molecule

Publications (2)

Publication Number Publication Date
BR112019005965A2 true BR112019005965A2 (pt) 2019-06-18
BR112019005965B1 BR112019005965B1 (pt) 2023-04-11

Family

ID=60083286

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112019005965-2A BR112019005965B1 (pt) 2016-09-28 2017-09-28 Composição compreendendo uma molécula bioativa, seu processo de preparação, produto agrícola ou alimentício e seu método de tratamento

Country Status (8)

Country Link
US (1) US11839217B2 (pt)
EP (1) EP3518677B1 (pt)
CN (1) CN110461150B (pt)
BR (1) BR112019005965B1 (pt)
DK (1) DK3518677T3 (pt)
ES (1) ES2906334T3 (pt)
NL (1) NL2017545B1 (pt)
WO (1) WO2018060321A1 (pt)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110938093B (zh) * 2018-09-21 2022-08-19 华创合成制药股份有限公司 一种泊沙康唑磷酸酯单胆碱盐及其制备方法和用途
US20220369630A1 (en) 2021-05-06 2022-11-24 Stoller Enterprises, Inc. Stable S-(+)-Abscisic Acid Nonaqueous Liquid Solutions
CN113278658B (zh) * 2021-05-21 2022-09-30 山东阜丰发酵有限公司 提高l-苹果酸发酵效率的生物工艺

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3892850A (en) * 1956-03-13 1975-07-01 Gist Brocades Nv Pimaricin and process of producing same
US6844004B2 (en) * 1997-08-15 2005-01-18 Board Of Regents, The University Of Texas System Topical formulations of natamycin/pimaricin
US7816332B2 (en) * 2003-06-02 2010-10-19 Dsm Ip Assets B.V. Stable aqueous solution of natamycin fungicide
GB2388581A (en) 2003-08-22 2003-11-19 Danisco Coated aqueous beads
WO2006045831A1 (en) 2004-10-28 2006-05-04 Dsm Ip Assets B.V. Stable needle-shaped crystals of natamycin
CN100526289C (zh) * 2004-12-06 2009-08-12 河北师范大学 无毒离子液体、制备方法及其应用
MX2011000930A (es) * 2008-07-24 2011-03-15 Valent Biosciences Corp Sales, composiciones liquidas acuosas que contienen sales de acido s- (+) -abscisico y metodos de su preparacion.
CN101700223A (zh) * 2009-12-08 2010-05-05 李荣立 环酯红霉素注射剂及其制备工艺
RU2560601C2 (ru) 2010-04-20 2015-08-20 ДАУ АГРОСАЙЕНСИЗ ЭлЭлСи Водные гербицидные концентраты ауксиновых карбоновых кислот, снижающие раздражающее действие на глаза
EP2505061A1 (en) 2011-03-30 2012-10-03 Rhodia Opérations New uses of choline chloride in agrochemical formulations
CN102742581B (zh) * 2012-07-20 2014-06-04 陕西省微生物研究所 纳他霉素-羟丙基-β-环糊精包合物的制备方法
CN104208017A (zh) * 2013-05-29 2014-12-17 镇江威特药业有限责任公司 一种伊维菌素溶液及其制备方法
GB2519787B (en) * 2013-10-30 2018-08-29 Rotam Agrochem Int Co Ltd Process for the preparation of herbicidal carboxylic acid salts
WO2015095312A1 (en) * 2013-12-20 2015-06-25 Valent Biosciences Corporation Low voc gibberellin formulations

Also Published As

Publication number Publication date
US20200029568A1 (en) 2020-01-30
CN110461150B (zh) 2022-04-01
WO2018060321A1 (en) 2018-04-05
EP3518677B1 (en) 2021-11-10
NL2017545B1 (en) 2018-04-06
DK3518677T3 (da) 2022-01-31
ES2906334T3 (es) 2022-04-18
CN110461150A (zh) 2019-11-15
EP3518677A1 (en) 2019-08-07
BR112019005965B1 (pt) 2023-04-11
US11839217B2 (en) 2023-12-12

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Legal Events

Date Code Title Description
B350 Update of information on the portal [chapter 15.35 patent gazette]
B06W Patent application suspended after preliminary examination (for patents with searches from other patent authorities) chapter 6.23 patent gazette]
B06A Patent application procedure suspended [chapter 6.1 patent gazette]
B09A Decision: intention to grant [chapter 9.1 patent gazette]
B16A Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]

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