BR112018075854A2 - sistema e método de fixação de conjunto de célula de fluxo - Google Patents

sistema e método de fixação de conjunto de célula de fluxo

Info

Publication number
BR112018075854A2
BR112018075854A2 BR112018075854-0A BR112018075854A BR112018075854A2 BR 112018075854 A2 BR112018075854 A2 BR 112018075854A2 BR 112018075854 A BR112018075854 A BR 112018075854A BR 112018075854 A2 BR112018075854 A2 BR 112018075854A2
Authority
BR
Brazil
Prior art keywords
flow cell
cell assembly
clamping system
assembly clamping
manifolds
Prior art date
Application number
BR112018075854-0A
Other languages
English (en)
Other versions
BR112018075854B1 (pt
Inventor
John De Ruyter Anthony
Kehl Patrick
Mcgee Thomas
Original Assignee
Illumina, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from NL2017853A external-priority patent/NL2017853B1/en
Priority claimed from US15/359,848 external-priority patent/US10718786B2/en
Application filed by Illumina, Inc. filed Critical Illumina, Inc.
Publication of BR112018075854A2 publication Critical patent/BR112018075854A2/pt
Publication of BR112018075854B1 publication Critical patent/BR112018075854B1/pt

Links

Classifications

    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502715Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by interfacing components, e.g. fluidic, electrical, optical or mechanical interfaces
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J19/00Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J19/0046Sequential or parallel reactions, e.g. for the synthesis of polypeptides or polynucleotides; Apparatus and devices for combinatorial chemistry or for making molecular arrays
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L9/00Supporting devices; Holding devices
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L9/00Supporting devices; Holding devices
    • B01L9/52Supports specially adapted for flat sample carriers, e.g. for plates, slides, chips
    • B01L9/527Supports specially adapted for flat sample carriers, e.g. for plates, slides, chips for microfluidic devices, e.g. used for lab-on-a-chip
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00Sampling; Preparing specimens for investigation
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00Sampling; Preparing specimens for investigation
    • G01N1/02Devices for withdrawing samples
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00Sampling; Preparing specimens for investigation
    • G01N1/02Devices for withdrawing samples
    • G01N1/10Devices for withdrawing samples in the liquid or fluent state
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/00029Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor provided with flat sample substrates, e.g. slides
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00277Apparatus
    • B01J2219/00477Means for pressurising the reaction vessels
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/02Adapting objects or devices to another
    • B01L2200/025Align devices or objects to ensure defined positions relative to each other
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/02Adapting objects or devices to another
    • B01L2200/026Fluid interfacing between devices or objects, e.g. connectors, inlet details
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/06Fluid handling related problems
    • B01L2200/0689Sealing
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00Additional constructional details
    • B01L2300/08Geometry, shape and general structure
    • B01L2300/0861Configuration of multiple channels and/or chambers in a single devices
    • B01L2300/0877Flow chambers
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00Additional constructional details
    • B01L2300/12Specific details about materials
    • B01L2300/123Flexible; Elastomeric
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N2035/00178Special arrangements of analysers
    • G01N2035/00237Handling microquantities of analyte, e.g. microvalves, capillary networks

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Clinical Laboratory Science (AREA)
  • Organic Chemistry (AREA)
  • Dispersion Chemistry (AREA)
  • Hematology (AREA)
  • Hydrology & Water Resources (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Optical Measuring Cells (AREA)
  • Sampling And Sample Adjustment (AREA)
  • Saccharide Compounds (AREA)
  • Information Retrieval, Db Structures And Fs Structures Therefor (AREA)
  • Fuel Cell (AREA)
  • Fluid-Pressure Circuits (AREA)

Abstract

um conjunto de célula de fluxo e cartucho pode ser carregado em um sistema de processamento, tal como para sequenciamento genético. o sistema localiza o conjunto e é então acionado para mover o conjunto para uma posição de referência desejada nas direções x e y. o acionamento adicional faz com que os grampos entrem em contato com a célula de fluxo, o cartucho ou ambos para exercer uma força de retenção durante o processamento. outras forças de retenção podem ser fornecidas por um mandril a vácuo. conexões de fluido também são feitas por coletores que entram em contato com a célula de fluxo. as forças de retenção neutralizam as forças necessárias para vedar os coletores à célula de fluxo.
BR112018075854-0A 2016-11-23 2017-11-15 Sistema e método de fixação de conjunto de células de fluxo BR112018075854B1 (pt)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
NLN2017853 2016-11-23
NL2017853A NL2017853B1 (en) 2016-11-23 2016-11-23 Flow cell assembly securement system and method
US15/359,848 US10718786B2 (en) 2016-11-23 2016-11-23 Flow cell assembly securement system and method
US15/359,848 2016-11-23
PCT/US2017/061824 WO2018097998A1 (en) 2016-11-23 2017-11-15 Flow cell assembly securement system and method

Publications (2)

Publication Number Publication Date
BR112018075854A2 true BR112018075854A2 (pt) 2019-03-19
BR112018075854B1 BR112018075854B1 (pt) 2023-05-02

Family

ID=60293905

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112018075854-0A BR112018075854B1 (pt) 2016-11-23 2017-11-15 Sistema e método de fixação de conjunto de células de fluxo

Country Status (17)

Country Link
EP (2) EP3995214A1 (pt)
JP (2) JP6888033B2 (pt)
KR (2) KR102624417B1 (pt)
CN (1) CN109416300B (pt)
AU (2) AU2017363511C1 (pt)
BR (1) BR112018075854B1 (pt)
CA (1) CA3026292C (pt)
DK (1) DK3326719T3 (pt)
ES (1) ES2902339T3 (pt)
IL (1) IL263946B (pt)
MY (1) MY192618A (pt)
PL (1) PL3326719T3 (pt)
RU (1) RU2743388C2 (pt)
SA (1) SA518400697B1 (pt)
SG (1) SG11201811614YA (pt)
TW (1) TWI759355B (pt)
WO (1) WO2018097998A1 (pt)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB201704769D0 (en) 2017-01-03 2017-05-10 Illumina Inc Flowcell cartridge with floating seal bracket

Family Cites Families (19)

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JPS5653368Y2 (pt) * 1979-02-27 1981-12-12
US5175086A (en) * 1983-01-24 1992-12-29 Olympus Optical Co., Ltd. Method for effecting heterogeneous immunological analysis
JPH01126565U (pt) * 1988-02-22 1989-08-29
JPH06167443A (ja) * 1992-10-23 1994-06-14 Olympus Optical Co Ltd 表面プラズモン共鳴を利用した測定装置
US20030129755A1 (en) * 2001-11-07 2003-07-10 Genvault Corporation System and method of storing and retrieving storage elements
TW579430B (en) * 2003-05-02 2004-03-11 Dr Chip Biotechnology Inc Automatic micro-fluid hybridization chip platform
EP1711264B1 (en) * 2004-02-02 2010-03-31 Silicon Valley Scientific, Inc. Integrated system with modular microfluidic components
US20060246576A1 (en) * 2005-04-06 2006-11-02 Affymetrix, Inc. Fluidic system and method for processing biological microarrays in personal instrumentation
JP4912096B2 (ja) * 2006-09-07 2012-04-04 ローム株式会社 マイクロチップ検査装置
DK2520643T3 (da) * 2007-12-07 2020-01-20 Miltenyi Biotec Bv & Co Kg Prøvebehandlingssystemer og -fremgangsmåder
RU2442973C2 (ru) * 2009-10-02 2012-02-20 Закрытое акционерное общество "ИММУНОСКРИН" (ЗАО "ИММУНОСКРИН") Иммунотурбидиметрический планшетный анализатор
US8545248B2 (en) * 2010-01-07 2013-10-01 Life Technologies Corporation System to control fluid flow based on a leak detected by a sensor
JP5499404B2 (ja) * 2010-05-21 2014-05-21 株式会社日立ハイテクノロジーズ フローセル固定装置及びそれを用いたdna分析装置
US8961906B2 (en) * 2010-07-27 2015-02-24 General Electric Company Fluid connector devices and methods of making and using the same
US8951781B2 (en) * 2011-01-10 2015-02-10 Illumina, Inc. Systems, methods, and apparatuses to image a sample for biological or chemical analysis
JP5965702B2 (ja) * 2012-04-03 2016-08-10 株式会社日立ハイテクノロジーズ フローセル、これを用いた分析装置、及び分析方法
AU2016235288B2 (en) * 2015-03-24 2019-02-28 Illumina Cambridge Limited Methods, carrier assemblies, and systems for imaging samples for biological or chemical analysis
CN105413769A (zh) * 2015-12-22 2016-03-23 苏州汶颢芯片科技有限公司 微流控芯片对准键合装置
CN205374483U (zh) * 2016-02-24 2016-07-06 北京乐普医疗科技有限责任公司 一种全自动荧光免疫定量分析设备

Also Published As

Publication number Publication date
SG11201811614YA (en) 2019-01-30
RU2018145442A (ru) 2020-12-24
IL263946A (en) 2019-01-31
AU2017363511B2 (en) 2022-03-31
AU2022204664A1 (en) 2022-07-21
AU2017363511C1 (en) 2022-10-06
MY192618A (en) 2022-08-29
IL263946B (en) 2022-04-01
CA3026292C (en) 2022-05-24
TW201830018A (zh) 2018-08-16
JP2019536000A (ja) 2019-12-12
AU2017363511A1 (en) 2018-12-20
EP3326719A1 (en) 2018-05-30
EP3326719B1 (en) 2021-10-06
RU2018145442A3 (pt) 2020-12-24
CN109416300B (zh) 2022-03-15
TWI759355B (zh) 2022-04-01
CA3026292A1 (en) 2018-05-31
ES2902339T3 (es) 2022-03-28
CN109416300A (zh) 2019-03-01
AU2022204664B2 (en) 2024-06-13
KR20210082550A (ko) 2021-07-05
KR102624417B1 (ko) 2024-01-11
DK3326719T3 (da) 2022-01-03
PL3326719T3 (pl) 2022-01-31
EP3995214A1 (en) 2022-05-11
WO2018097998A1 (en) 2018-05-31
SA518400697B1 (ar) 2023-02-06
JP2021144042A (ja) 2021-09-24
KR20190089120A (ko) 2019-07-30
JP6888033B2 (ja) 2021-06-16
JP7241125B2 (ja) 2023-03-16
KR102271703B1 (ko) 2021-07-02
BR112018075854B1 (pt) 2023-05-02
RU2743388C2 (ru) 2021-02-17

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B350 Update of information on the portal [chapter 15.35 patent gazette]
B06W Patent application suspended after preliminary examination (for patents with searches from other patent authorities) chapter 6.23 patent gazette]
B09A Decision: intention to grant [chapter 9.1 patent gazette]
B09W Correction of the decision to grant [chapter 9.1.4 patent gazette]

Free format text: RETIFIQUE-SE PARA CORRECAO DE ERRO NA NUMERACAO DAS REIVINDICACOES

B16A Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]

Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 15/11/2017, OBSERVADAS AS CONDICOES LEGAIS