BR112018073566A2 - lentes intra-oculares hidrofóbicas - Google Patents

lentes intra-oculares hidrofóbicas

Info

Publication number
BR112018073566A2
BR112018073566A2 BR112018073566-3A BR112018073566A BR112018073566A2 BR 112018073566 A2 BR112018073566 A2 BR 112018073566A2 BR 112018073566 A BR112018073566 A BR 112018073566A BR 112018073566 A2 BR112018073566 A2 BR 112018073566A2
Authority
BR
Brazil
Prior art keywords
meth
acrylate
polymerized
monomer
subunit
Prior art date
Application number
BR112018073566-3A
Other languages
English (en)
Other versions
BR112018073566B1 (pt
Inventor
H. Benz Patrick
Reboul Adam
Original Assignee
Benz Research And Development Corp.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Benz Research And Development Corp. filed Critical Benz Research And Development Corp.
Publication of BR112018073566A2 publication Critical patent/BR112018073566A2/pt
Publication of BR112018073566B1 publication Critical patent/BR112018073566B1/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/14—Eye parts, e.g. lenses, corneal implants; Implanting instruments specially adapted therefor; Artificial eyes
    • A61F2/16—Intraocular lenses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14—Macromolecular materials
    • A61L27/16—Macromolecular materials obtained by reactions only involving carbon-to-carbon unsaturated bonds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29D—PRODUCING PARTICULAR ARTICLES FROM PLASTICS OR FROM SUBSTANCES IN A PLASTIC STATE
    • B29D11/00—Producing optical elements, e.g. lenses or prisms
    • B29D11/02—Artificial eyes from organic plastic material
    • B29D11/023—Implants for natural eyes
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F2/00—Processes of polymerisation
    • C08F2/46—Polymerisation initiated by wave energy or particle radiation
    • C08F2/48—Polymerisation initiated by wave energy or particle radiation by ultraviolet or visible light
    • C08F2/50—Polymerisation initiated by wave energy or particle radiation by ultraviolet or visible light with sensitising agents
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F220/00—Copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and only one being terminated by only one carboxyl radical or a salt, anhydride ester, amide, imide or nitrile thereof
    • C08F220/02—Monocarboxylic acids having less than ten carbon atoms; Derivatives thereof
    • C08F220/10—Esters
    • C08F220/22—Esters containing halogen
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F220/00—Copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and only one being terminated by only one carboxyl radical or a salt, anhydride ester, amide, imide or nitrile thereof
    • C08F220/02—Monocarboxylic acids having less than ten carbon atoms; Derivatives thereof
    • C08F220/10—Esters
    • C08F220/26—Esters containing oxygen in addition to the carboxy oxygen
    • C08F220/30—Esters containing oxygen in addition to the carboxy oxygen containing aromatic rings in the alcohol moiety
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F220/00—Copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and only one being terminated by only one carboxyl radical or a salt, anhydride ester, amide, imide or nitrile thereof
    • C08F220/02—Monocarboxylic acids having less than ten carbon atoms; Derivatives thereof
    • C08F220/52—Amides or imides
    • C08F220/54—Amides, e.g. N,N-dimethylacrylamide or N-isopropylacrylamide
    • C08F220/56—Acrylamide; Methacrylamide
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F220/00—Copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and only one being terminated by only one carboxyl radical or a salt, anhydride ester, amide, imide or nitrile thereof
    • C08F220/62—Monocarboxylic acids having ten or more carbon atoms; Derivatives thereof
    • C08F220/68—Esters
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L27/00—Compositions of homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by a halogen; Compositions of derivatives of such polymers
    • C08L27/02—Compositions of homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by a halogen; Compositions of derivatives of such polymers not modified by chemical after-treatment
    • C08L27/10—Compositions of homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by a halogen; Compositions of derivatives of such polymers not modified by chemical after-treatment containing bromine or iodine atoms
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L29/00—Compositions of homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by an alcohol, ether, aldehydo, ketonic, acetal or ketal radical; Compositions of hydrolysed polymers of esters of unsaturated alcohols with saturated carboxylic acids; Compositions of derivatives of such polymers
    • C08L29/02—Homopolymers or copolymers of unsaturated alcohols
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L33/00—Compositions of homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and only one being terminated by only one carboxyl radical, or of salts, anhydrides, esters, amides, imides or nitriles thereof; Compositions of derivatives of such polymers
    • C08L33/04—Homopolymers or copolymers of esters
    • C08L33/06—Homopolymers or copolymers of esters of esters containing only carbon, hydrogen and oxygen, which oxygen atoms are present only as part of the carboxyl radical
    • C08L33/08—Homopolymers or copolymers of acrylic acid esters
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L33/00—Compositions of homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and only one being terminated by only one carboxyl radical, or of salts, anhydrides, esters, amides, imides or nitriles thereof; Compositions of derivatives of such polymers
    • C08L33/04—Homopolymers or copolymers of esters
    • C08L33/14—Homopolymers or copolymers of esters of esters containing halogen, nitrogen, sulfur, or oxygen atoms in addition to the carboxy oxygen
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L33/00—Compositions of homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and only one being terminated by only one carboxyl radical, or of salts, anhydrides, esters, amides, imides or nitriles thereof; Compositions of derivatives of such polymers
    • C08L33/24—Homopolymers or copolymers of amides or imides
    • C08L33/26—Homopolymers or copolymers of acrylamide or methacrylamide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2210/00—Particular material properties of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2210/0095—Particular material properties of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof radioactive
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2250/00—Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2250/0014—Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof having different values of a given property or geometrical feature, e.g. mechanical property or material property, at different locations within the same prosthesis
    • A61F2250/0056—Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof having different values of a given property or geometrical feature, e.g. mechanical property or material property, at different locations within the same prosthesis differing in wettability, e.g. in hydrophilic or hydrophobic behaviours
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2430/00—Materials or treatment for tissue regeneration
    • A61L2430/16—Materials or treatment for tissue regeneration for reconstruction of eye parts, e.g. intraocular lens, cornea
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F2810/00—Chemical modification of a polymer
    • C08F2810/20—Chemical modification of a polymer leading to a crosslinking, either explicitly or inherently

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Polymers & Plastics (AREA)
  • Organic Chemistry (AREA)
  • Ophthalmology & Optometry (AREA)
  • Engineering & Computer Science (AREA)
  • Transplantation (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Dermatology (AREA)
  • Cardiology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Mechanical Engineering (AREA)
  • Manufacturing & Machinery (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Materials For Medical Uses (AREA)
  • Prostheses (AREA)

Abstract

a presente invenção refere-se a uma lente intra-ocular (iol) possuindo excelentes características hidrofóbico não intermitente, um número de abbe elevado, excelentes propriedades mecânicas que compreendem, pelo menos, um copolímero compreendendo: (a) uma primeira subunidade monomérica compreendendo um (met)acrilato polimerizado e o pelo menos um grupo alcoxialcoxialquila lado, (b) uma segunda, diferente monómero de subunidade para o primeiro monómero de subunidade que compreende um (met)acrilato polimerizado, pelo menos um grupo lateral, incluindo (i) uma porção ariloxi com pelo menos um halogêneo, e (ii) uma fração de pasta de carbono fragmento ariloxi alifático (met) acrilato polimerizado, a fração de carbono alifático que compreende pelo menos um substituinte hidroxila.
BR112018073566-3A 2016-05-16 2017-05-15 Lente intraocular, composição compreendendo pelo menos um copolímero e método para preparar a referida composição BR112018073566B1 (pt)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201662337318P 2016-05-16 2016-05-16
US62/337,318 2016-05-16
US15/481,791 US10196470B2 (en) 2016-05-16 2017-04-07 Hydrophobic intraocular lens
US15/481,791 2017-04-07
PCT/US2017/032698 WO2017200934A1 (en) 2016-05-16 2017-05-15 Hydrophobic intraocular lens

Publications (2)

Publication Number Publication Date
BR112018073566A2 true BR112018073566A2 (pt) 2019-03-19
BR112018073566B1 BR112018073566B1 (pt) 2022-02-01

Family

ID=60295001

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112018073566-3A BR112018073566B1 (pt) 2016-05-16 2017-05-15 Lente intraocular, composição compreendendo pelo menos um copolímero e método para preparar a referida composição

Country Status (13)

Country Link
US (2) US10196470B2 (pt)
EP (1) EP3458118B1 (pt)
JP (2) JP7430488B2 (pt)
KR (1) KR102461736B1 (pt)
CN (1) CN109475660B (pt)
AU (1) AU2017266896C1 (pt)
BR (1) BR112018073566B1 (pt)
CA (1) CA3024314A1 (pt)
ES (1) ES2903052T3 (pt)
IL (1) IL263023B (pt)
MX (1) MX2018013978A (pt)
RU (1) RU2745207C2 (pt)
WO (1) WO2017200934A1 (pt)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20200330643A1 (en) * 2017-05-16 2020-10-22 Benz Research And Development Corp. Micro injectable, low chromatic aberration intraocular lens materials
US11708440B2 (en) * 2019-05-03 2023-07-25 Johnson & Johnson Surgical Vision, Inc. High refractive index, high Abbe compositions
CN111467581B (zh) * 2020-04-14 2022-04-12 广东赛珐生物科技有限公司 青光眼引流管及其制备方法
NL2026797B1 (nl) 2020-10-30 2022-06-24 Ophtec Bv Intraoculaire lens, inbrenggereedschap daarvoor, samenstel voorzien daarvan, en werkwijze voor vervaardiging
CN113321763A (zh) * 2021-08-02 2021-08-31 微创视神医疗科技(上海)有限公司 一种聚合物及其应用、以及眼科医疗器材

Family Cites Families (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU634338B2 (en) 1990-02-08 1993-02-18 Mitsubishi Rayon Company Limited Composition for plastic lenses
JP2849173B2 (ja) * 1990-07-05 1999-01-20 三菱レイヨン株式会社 プラスチックレンズ用組成物
US5217491A (en) 1990-12-27 1993-06-08 American Cyanamid Company Composite intraocular lens
RU2052983C1 (ru) * 1994-02-14 1996-01-27 Акционерное общество закрытого типа "МНТК-МГ" Искусственный хрусталик глаза и способ его изготовления
US6011081A (en) 1995-04-14 2000-01-04 Benz Research And Development Corp. Contact lens having improved dimensional stability
DE69625161T2 (de) 1995-06-07 2003-04-17 Alcon Lab Inc Material für ophtalmische linsen mit hohem brechungsindex
ZA9810605B (en) 1997-11-21 1999-05-25 Cytec Techonoly Corp Trisaryl-1,3,5-triazine ultraviolet light absorbers
WO1999056167A1 (fr) * 1998-04-28 1999-11-04 Toray Industries, Inc. Production de lentille oculaire
US6267784B1 (en) 1998-05-01 2001-07-31 Benz Research And Development Corporation Intraocular lens and haptics made of a copolymer
US6096799A (en) 1998-05-07 2000-08-01 Benz Research & Development Corporation Contact lens of high water content and high water balance
US6281319B1 (en) * 1999-04-12 2001-08-28 Surgidev Corporation Water plasticized high refractive index polymer for ophthalmic applications
US8247511B2 (en) * 1999-04-12 2012-08-21 Advanced Vision Science, Inc. Water plasticized high refractive index polymer for ophthalmic applications
WO2000079312A1 (en) 1999-06-17 2000-12-28 Bausch & Lomb Surgical, Inc. High refractive index compositions for ophthalmic implants
BR0013779A (pt) 1999-09-07 2002-05-14 Alcon Universal Ltd Materiais de dispositivos oftal-mológicos e otorrinolaringológicos
ES2441245T3 (es) 2003-11-05 2014-02-03 Benz Research And Development Corporation Materiales para la fabricación de lentes intraoculares hidrofóbicas
US7387642B2 (en) 2005-04-13 2008-06-17 Benz Research And Development Corporation Polymers for intraocular lenses
US7652076B2 (en) * 2005-06-13 2010-01-26 Alcon, Inc. Ophthalmic and otorhinolaryngological device materials
EP1792923B1 (de) * 2005-12-01 2011-03-30 CORONIS GmbH Polymerzusammensetzung mit hohem Brechungsindex
EP1818690A1 (en) * 2006-02-14 2007-08-15 Procornea Holding B.V. Intraocular lenses essentially free from glistenings
US9060847B2 (en) * 2008-05-19 2015-06-23 University Of Rochester Optical hydrogel material with photosensitizer and method for modifying the refractive index
US8729203B2 (en) 2009-05-07 2014-05-20 Timothy Charles Higgs Polymer composition
CN101564551B (zh) * 2009-06-05 2012-07-25 北京科技大学 一种丙烯酸酯类形状记忆性人工晶状体材料及制备方法
TWI551646B (zh) * 2011-06-03 2016-10-01 諾華公司 疏水性丙烯酸系眼內水晶體材料
ES2638897T3 (es) 2011-09-16 2017-10-24 Benz Research And Development Corporation Materiales absorbentes de luz ultravioleta para lentes intraoculares y usos de los mismos
CA2848978C (en) * 2011-09-16 2020-01-14 Benz Research And Development Corp. Hydrophobic intraocular lens
US9244196B2 (en) * 2012-05-25 2016-01-26 Johnson & Johnson Vision Care, Inc. Polymers and nanogel materials and methods for making and using the same
WO2015161199A1 (en) 2014-04-18 2015-10-22 Benz Research And Development Corp. (meth)acrylamide polymers for contact lens and intraocular lens
CN105536053B (zh) * 2015-12-29 2018-10-02 哈尔滨工业大学 一种作为人工晶状体材料的亲水性形状记忆水凝胶

Also Published As

Publication number Publication date
WO2017200934A1 (en) 2017-11-23
AU2017266896B2 (en) 2021-06-03
JP2019516507A (ja) 2019-06-20
US10899862B2 (en) 2021-01-26
CN109475660A (zh) 2019-03-15
US20180334520A1 (en) 2018-11-22
JP7425105B2 (ja) 2024-01-30
AU2017266896C1 (en) 2021-09-16
US20170327615A1 (en) 2017-11-16
RU2018140896A3 (pt) 2020-08-28
EP3458118A1 (en) 2019-03-27
IL263023A (en) 2018-12-31
KR102461736B1 (ko) 2022-11-01
JP2022095900A (ja) 2022-06-28
CA3024314A1 (en) 2017-11-23
ES2903052T3 (es) 2022-03-30
BR112018073566B1 (pt) 2022-02-01
RU2018140896A (ru) 2020-06-17
KR20190009316A (ko) 2019-01-28
IL263023B (en) 2021-02-28
AU2017266896A1 (en) 2018-12-06
CN109475660B (zh) 2022-03-22
RU2745207C2 (ru) 2021-03-22
MX2018013978A (es) 2019-06-24
US10196470B2 (en) 2019-02-05
JP7430488B2 (ja) 2024-02-13
EP3458118B1 (en) 2021-10-27

Similar Documents

Publication Publication Date Title
BR112018073566A2 (pt) lentes intra-oculares hidrofóbicas
MX2019007114A (es) Materiales hidrofilicos con alto indice refractivo.
BR112014006188A2 (pt) lentes hidrofóbicas intraoculares
BR112016001744A2 (pt) composição polimerizável para material ótico fotocrômico
BR112021026412A2 (pt) Lentes oftálmicas e métodos para corrigir, retardar, reduzir e/ou controlar a progressão da miopia
WO2015198236A3 (en) Accommodative intraocular lens
PH12018500928A1 (en) Reticle for optical sighting devices
BR112017005029A2 (pt) válvula cardíaca prostética com elementos de retenção
BR112021026265A2 (pt) Métodos e sistemas de entrega de dispositivos oculares
MX2016017033A (es) Superelastomeros de copolimero de injerto multiple mediante polimerizacion por emulsion.
WO2012071146A3 (en) Intraocular lens
CL2017002756A1 (es) Adhesivos acrílicos en emulsión
EP3897460A4 (en) QINTAFOCAL DIFFRACTIVE INTRAOCULAR LENS
BR112017000044A2 (pt) método de preparação de copolímero zwitteriônico, solução de copolímero zwitteriônico, e composição de revestimento resistente a incrustações
DK3373992T3 (da) Acrylpolymer, som er hydrofob, tværbundet og baseret på kanelalkohol, til intraokulære linser
BR112017017187A2 (pt) copolímeros de blocos e sua utilização para melhorar as propriedades a frio de carburantes ou combustíveis
BR112018072343A2 (pt) método de determinação de um filtro para uma lente oftálmica em função de uma grandeza representativa de uma sensibilidade dinâmica do olho de um portador a uma variação de um fluxo luminoso
WO2012138426A3 (en) An implantable ophthalmic device with multiple static apertures
BR112018008803A2 (pt) composições de cianoacrilato
EP3651693A4 (en) PSEUDOPHAQUE INTRAOCULAR CONTACT LENS WITH ANTERIOR SHEET MECHANISM OF THE CAPSULAR WALL AND ASSOCIATED SYSTEM AND METHOD
EP4022502A4 (en) HIGH POWERFUL TRACKING OF AN EYE WITH A BRIGHT PUPILL
BR112014029127A2 (pt) método de fazer uma lente de hidrogel de silicone totalmente polimerizada bloqueadora de uv
BR112019002540A2 (pt) composição à base de monômeros alílicos e de peróxido(s) para a fabricação de vidros orgânicos
EP3849470A4 (en) MULTIFOCAL INTRAOCULAR LENS
AR099066A1 (es) Polímeros que comprenden grupos de ácido sulfónico

Legal Events

Date Code Title Description
B06W Patent application suspended after preliminary examination (for patents with searches from other patent authorities) chapter 6.23 patent gazette]
B350 Update of information on the portal [chapter 15.35 patent gazette]
B09A Decision: intention to grant [chapter 9.1 patent gazette]
B16A Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]

Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 15/05/2017, OBSERVADAS AS CONDICOES LEGAIS.