BR112018071467A2 - método de tratamento ou prevenção de patologias hepáticas - Google Patents
método de tratamento ou prevenção de patologias hepáticasInfo
- Publication number
- BR112018071467A2 BR112018071467A2 BR112018071467A BR112018071467A BR112018071467A2 BR 112018071467 A2 BR112018071467 A2 BR 112018071467A2 BR 112018071467 A BR112018071467 A BR 112018071467A BR 112018071467 A BR112018071467 A BR 112018071467A BR 112018071467 A2 BR112018071467 A2 BR 112018071467A2
- Authority
- BR
- Brazil
- Prior art keywords
- prevention
- treatment
- liver disorders
- individual
- signaling
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/22—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against growth factors ; against growth regulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7088—Compounds having three or more nucleosides or nucleotides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
- C12N15/1136—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing against growth factors, growth regulators, cytokines, lymphokines or hormones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/545—Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Biomedical Technology (AREA)
- General Chemical & Material Sciences (AREA)
- Gastroenterology & Hepatology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Immunology (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Epidemiology (AREA)
- Physics & Mathematics (AREA)
- Microbiology (AREA)
- Plant Pathology (AREA)
- Endocrinology (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
a presente divulgação fornece um método de tratamento de uma doença de esteatose hepática não alcóolica num indivíduo, em que o método compreende administrar ao indivíduo um composto que inibe a sinalização de vegf-b.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
AU2016901483A AU2016901483A0 (en) | 2016-04-21 | Methods of treating or preventing liver conditions | |
AU2016901494A AU2016901494A0 (en) | 2016-04-21 | Method of treating or preventing liver conditions | |
PCT/AU2017/050364 WO2017181243A1 (en) | 2016-04-21 | 2017-04-21 | Method of treating or preventing liver conditions |
Publications (1)
Publication Number | Publication Date |
---|---|
BR112018071467A2 true BR112018071467A2 (pt) | 2019-02-05 |
Family
ID=60115684
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR112018071467A BR112018071467A2 (pt) | 2016-04-21 | 2017-04-21 | método de tratamento ou prevenção de patologias hepáticas |
Country Status (10)
Country | Link |
---|---|
US (2) | US20190119369A1 (pt) |
EP (1) | EP3445450A4 (pt) |
JP (1) | JP7065786B2 (pt) |
KR (1) | KR102513989B1 (pt) |
CN (1) | CN109310884B (pt) |
AU (1) | AU2017254775B2 (pt) |
BR (1) | BR112018071467A2 (pt) |
CA (1) | CA3020988A1 (pt) |
RU (2) | RU2021136970A (pt) |
WO (1) | WO2017181243A1 (pt) |
Families Citing this family (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DK2718326T3 (da) | 2011-06-13 | 2020-10-26 | Csl Ltd | Antistoffer mod g-csfr og anvendelser deraf |
CN107661492A (zh) * | 2017-08-31 | 2018-02-06 | 中山大学中山眼科中心 | Vegf‑b的新用途 |
EP3717011B1 (en) * | 2017-11-29 | 2022-12-07 | CSL Limited | Method of treating or preventing ischemia-reperfusion injury |
WO2020056459A1 (en) * | 2018-09-18 | 2020-03-26 | Csl Limited | Method of treating wasting disorders |
IT201900005700A1 (it) * | 2019-04-12 | 2020-10-12 | Metadeq Ltd | Nuovo marcatore di patologia e suoi usi |
CN112010971A (zh) * | 2019-05-30 | 2020-12-01 | 义慧科技(深圳)有限公司 | 抗vegf抗体在制备预防和/或治疗脂肪肝的药物中的应用 |
KR102280261B1 (ko) * | 2019-07-16 | 2021-07-20 | 이화여자대학교 산학협력단 | 대사체 분석을 이용한 간질환의 진단 방법 |
CN114470000A (zh) * | 2020-11-11 | 2022-05-13 | 上海萨美细胞技术有限公司 | 无细胞脂肪提取液对非酒精性脂肪肝炎的治疗用途 |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US8822644B2 (en) * | 2004-08-02 | 2014-09-02 | Zenyth Operations Pty Ltd | Method of treating cancer comprising a VEGF-B antagonist |
ES2497641T3 (es) * | 2006-05-17 | 2014-09-23 | The Ludwig Institute For Cancer Research | Dirección a la regulación de VEGF-B de transportadores de ácidos grasos para modular enfermedades humanas |
AU2013224763B2 (en) * | 2006-05-17 | 2016-06-30 | Ludwig Institute For Cancer Research | Targeting VEGF-B regulation of fatty acid transporters to modulate human diseases |
US20080194575A1 (en) * | 2006-10-04 | 2008-08-14 | Naiara Beraza | Treatment for non-alcoholic-steatohepatitis |
WO2009045356A2 (en) * | 2007-09-28 | 2009-04-09 | Yale University | Microrna compositions in the treatment of vegf-mediated disorders |
WO2009126698A2 (en) | 2008-04-09 | 2009-10-15 | Ludwig Institute For Cancer Research | Regulation of fatty acid transporters |
WO2015077845A1 (en) * | 2013-11-28 | 2015-06-04 | Csl Limited | Method of treating nephropathy |
EP3082860B1 (en) * | 2013-12-18 | 2020-11-25 | CSL Limited | Method of treating wounds |
-
2017
- 2017-04-21 BR BR112018071467A patent/BR112018071467A2/pt active Search and Examination
- 2017-04-21 RU RU2021136970A patent/RU2021136970A/ru unknown
- 2017-04-21 RU RU2018139893A patent/RU2018139893A/ru unknown
- 2017-04-21 WO PCT/AU2017/050364 patent/WO2017181243A1/en active Application Filing
- 2017-04-21 EP EP17785174.8A patent/EP3445450A4/en active Pending
- 2017-04-21 JP JP2018555146A patent/JP7065786B2/ja active Active
- 2017-04-21 KR KR1020187032889A patent/KR102513989B1/ko active IP Right Grant
- 2017-04-21 US US16/095,021 patent/US20190119369A1/en not_active Abandoned
- 2017-04-21 CN CN201780038503.XA patent/CN109310884B/zh active Active
- 2017-04-21 CA CA3020988A patent/CA3020988A1/en active Pending
- 2017-04-21 AU AU2017254775A patent/AU2017254775B2/en active Active
-
2022
- 2022-11-09 US US18/053,857 patent/US20240002488A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
US20240002488A1 (en) | 2024-01-04 |
US20190119369A1 (en) | 2019-04-25 |
RU2021136970A (ru) | 2022-04-01 |
EP3445450A1 (en) | 2019-02-27 |
KR102513989B1 (ko) | 2023-03-24 |
RU2018139893A3 (pt) | 2020-06-25 |
AU2017254775A1 (en) | 2018-11-08 |
WO2017181243A1 (en) | 2017-10-26 |
CN109310884B (zh) | 2022-10-28 |
AU2017254775B2 (en) | 2023-06-29 |
CA3020988A1 (en) | 2017-10-26 |
KR20180135928A (ko) | 2018-12-21 |
CN109310884A (zh) | 2019-02-05 |
RU2018139893A (ru) | 2020-05-21 |
JP2019514875A (ja) | 2019-06-06 |
EP3445450A4 (en) | 2020-01-08 |
JP7065786B2 (ja) | 2022-05-12 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
B07D | Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette] |
Free format text: DE ACORDO COM O ARTIGO 229-C DA LEI NO 10196/2001, QUE MODIFICOU A LEI NO 9279/96, A CONCESSAO DA PATENTE ESTA CONDICIONADA A ANUENCIA PREVIA DA ANVISA. CONSIDERANDO A APROVACAO DOS TERMOS DO PARECER NO 337/PGF/EA/2010, BEM COMO A PORTARIA INTERMINISTERIAL NO 1065 DE 24/05/2012, ENCAMINHA-SE O PRESENTE PEDIDO PARA AS PROVIDENCIAS CABIVEIS. |
|
B07E | Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette] | ||
B06W | Patent application suspended after preliminary examination (for patents with searches from other patent authorities) chapter 6.23 patent gazette] | ||
B350 | Update of information on the portal [chapter 15.35 patent gazette] |