BR112018070345A2 - processo para a preparação de derivados de 4-aminoindano e amidas de aminoindano relacionadas - Google Patents

processo para a preparação de derivados de 4-aminoindano e amidas de aminoindano relacionadas

Info

Publication number
BR112018070345A2
BR112018070345A2 BR112018070345A BR112018070345A BR112018070345A2 BR 112018070345 A2 BR112018070345 A2 BR 112018070345A2 BR 112018070345 A BR112018070345 A BR 112018070345A BR 112018070345 A BR112018070345 A BR 112018070345A BR 112018070345 A2 BR112018070345 A2 BR 112018070345A2
Authority
BR
Brazil
Prior art keywords
aminoindan
preparation
amides
derivatives
formula
Prior art date
Application number
BR112018070345A
Other languages
English (en)
Other versions
BR112018070345B1 (pt
Inventor
Devarajan Chockalingam
Zanardi Giampaolo
Swamy Narayana
Bellandi Paolo
Vitthal Datar Ravindra
Murali Swamynathan
Original Assignee
Stichting I F Product Collaboration
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Stichting I F Product Collaboration filed Critical Stichting I F Product Collaboration
Publication of BR112018070345A2 publication Critical patent/BR112018070345A2/pt
Publication of BR112018070345B1 publication Critical patent/BR112018070345B1/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/60—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C209/00—Preparation of compounds containing amino groups bound to a carbon skeleton
    • C07C209/62—Preparation of compounds containing amino groups bound to a carbon skeleton by cleaving carbon-to-nitrogen, sulfur-to-nitrogen, or phosphorus-to-nitrogen bonds, e.g. hydrolysis of amides, N-dealkylation of amines or quaternary ammonium compounds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C209/00—Preparation of compounds containing amino groups bound to a carbon skeleton
    • C07C209/68—Preparation of compounds containing amino groups bound to a carbon skeleton from amines, by reactions not involving amino groups, e.g. reduction of unsaturated amines, aromatisation, or substitution of the carbon skeleton
    • C07C209/70—Preparation of compounds containing amino groups bound to a carbon skeleton from amines, by reactions not involving amino groups, e.g. reduction of unsaturated amines, aromatisation, or substitution of the carbon skeleton by reduction of unsaturated amines
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C231/00—Preparation of carboxylic acid amides
    • C07C231/02—Preparation of carboxylic acid amides from carboxylic acids or from esters, anhydrides, or halides thereof by reaction with ammonia or amines
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C231/00—Preparation of carboxylic acid amides
    • C07C231/08—Preparation of carboxylic acid amides from amides by reaction at nitrogen atoms of carboxamide groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C231/00—Preparation of carboxylic acid amides
    • C07C231/14—Preparation of carboxylic acid amides by formation of carboxamide groups together with reactions not involving the carboxamide groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/18—Halogen atoms or nitro radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2602/00—Systems containing two condensed rings
    • C07C2602/02—Systems containing two condensed rings the rings having only two atoms in common
    • C07C2602/04—One of the condensed rings being a six-membered aromatic ring
    • C07C2602/08—One of the condensed rings being a six-membered aromatic ring the other ring being five-membered, e.g. indane

Abstract

a presente invenção refere-se a um processo para a preparação de derivados de 4-aminoindano de fórmula (i) (i). a presente invenção também se refere a um processo para a preparação de amidas de aminoindano de fórmula (ii), tendo atividade fungicida, partindo de um intermediário de derivado de 4-aminoindano de fórmula (i) obtido através do processo acima mencionado. (ii)
BR112018070345-1A 2016-04-15 2016-04-15 Processo para a preparação de derivados de 4-aminoindano, sais e enantiômeros dos mesmos, e processo para a preparação de amidas de aminoindano BR112018070345B1 (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/IB2016/052169 WO2017178868A1 (en) 2016-04-15 2016-04-15 Process for the preparation of 4-aminoindane derivatives and related aminoindane amides

Publications (2)

Publication Number Publication Date
BR112018070345A2 true BR112018070345A2 (pt) 2019-01-29
BR112018070345B1 BR112018070345B1 (pt) 2022-01-18

Family

ID=55795012

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112018070345-1A BR112018070345B1 (pt) 2016-04-15 2016-04-15 Processo para a preparação de derivados de 4-aminoindano, sais e enantiômeros dos mesmos, e processo para a preparação de amidas de aminoindano

Country Status (10)

Country Link
US (3) US10640454B2 (pt)
EP (1) EP3442944B1 (pt)
JP (1) JP6780011B2 (pt)
CN (1) CN109071439B (pt)
BR (1) BR112018070345B1 (pt)
DK (1) DK3442944T3 (pt)
ES (1) ES2806460T3 (pt)
HU (1) HUE051536T2 (pt)
PL (1) PL3442944T3 (pt)
WO (1) WO2017178868A1 (pt)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2806460T3 (es) * 2016-04-15 2021-02-17 Stichting I F Product Collaboration Proceso para la preparación de derivados de 4-aminoindano y amidas de aminoindano relacionadas
CN108276329B (zh) * 2018-04-02 2020-05-08 金凯(辽宁)化工有限公司 一种6-氟-2,2,4-三甲基-1,2-二氢喹啉的制备方法
WO2019224181A1 (en) 2018-05-23 2019-11-28 Bayer Aktiengesellschaft Process for producing substituted 4-aminoindanes
IT201900017330A1 (it) 2019-09-26 2021-03-26 Isagro Spa Processo per la preparazione di (r)-4-amminoindani e corrispondenti ammidi.

Family Cites Families (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4742074A (en) * 1984-10-29 1988-05-03 Sumitomo Chemical Company, Limited Pyrazolecarboxamide derivative and fungicide containing it as active ingredient
DK383086A (da) 1985-08-21 1987-02-22 Rohm & Haas (2-cyano-2-arylethyl)pyridiner, deres fremstilling og deres anvendelse som fungicider
DE3782883T2 (de) 1986-08-12 1993-06-09 Mitsubishi Chem Ind Pyridincarboxamid-derivate und ihre verwendung als fungizides mittel.
US4837242A (en) 1987-01-20 1989-06-06 Sumitomo Chemical Company, Limited Thiazoles and pyrazoles as fungicides
US4914097A (en) 1987-02-25 1990-04-03 Mitsubishi Kasei Corporation N-indanyl carboxamide derivative and agricultural/horticultural fungicide containing the derivative as active ingredient
JP2582863B2 (ja) 1988-06-13 1997-02-19 三菱化学株式会社 Ｎ−インダニルカルボン酸アミド誘導体を有効成分とする灰色かび病防除剤
JP2717852B2 (ja) 1988-12-09 1998-02-25 株式会社紀文食品 冷凍すり身の鮮度測定法
JPH02157266A (ja) 1988-12-12 1990-06-18 Mitsubishi Kasei Corp Ｎ−インダニルカルボン酸アミド誘導体およびこれを有効成分とする農園芸用殺菌剤
US5093347A (en) 1991-01-28 1992-03-03 Monsanto Company 3-difluoromethylpyrazolecarboxamide fungicides, compositions and use
JP3077381B2 (ja) 1992-05-14 2000-08-14 住友化学工業株式会社 木材防腐剤
HUT63941A (en) 1992-05-15 1993-11-29 Hoechst Ag Process for producing 4-alkyl-substituted pyrimidine-5-carboxanilide derivatives, and fungicidal compositions comprising same
EP0654464A1 (en) 1993-10-22 1995-05-24 Shell Internationale Researchmaatschappij B.V. Processes for the preparation of pesticides and intermediates
US5521317A (en) 1993-10-22 1996-05-28 American Cyanamid Co. Processes for the preparation of pesticides and intermediates
JPH1070479A (ja) 1996-08-29 1998-03-10 Nippon Seiki Co Ltd Ｆｍ多重受信機
JP3675112B2 (ja) 1997-06-23 2005-07-27 富士写真フイルム株式会社 画像読取装置及び情報処理装置
GB0001447D0 (en) 2000-01-21 2000-03-08 Novartis Ag Organic compounds
WO2004018438A2 (en) 2002-08-22 2004-03-04 Syngenta Participations Ag Microbiocidal (e.g. fungicidal) 1,2,3-triazole derivatives
DE10250110A1 (de) 2002-10-28 2004-05-13 Bayer Cropscience Ag Thiazol-(bi)cycloalkyl-carboxanilide
PT1599460E (pt) 2003-02-14 2008-02-08 Bayer Cropscience Ag Oxatiina-carboxamidas
US7687531B2 (en) 2003-05-21 2010-03-30 Bayer Cropscience Ag Iodopyrazolyl carboxanilides
DE102004005785A1 (de) 2004-02-06 2005-08-25 Bayer Cropscience Ag 2-Halogenfuryl/thienyl-3-carboxamide
ITMI20090488A1 (it) * 2009-03-27 2010-09-28 Isagro Ricerca Srl Composti benzammidici ad elevata attivita' fungicida e relativo uso
IT1403275B1 (it) 2010-12-20 2013-10-17 Isagro Ricerca Srl Indanilanilidi ad elevata attività fungicida e loro composizioni fitosanitarie
ITMI20121045A1 (it) 2012-06-15 2013-12-16 Isagro Ricerca Srl Composizioni sinergiche per la protezione di colture agrarie e relativo uso
BR112015015097B1 (pt) * 2012-12-27 2021-02-17 Sumitomo Chemical Company, Limited método para produção de composto de amina purificada
ES2806460T3 (es) * 2016-04-15 2021-02-17 Stichting I F Product Collaboration Proceso para la preparación de derivados de 4-aminoindano y amidas de aminoindano relacionadas

Also Published As

Publication number Publication date
CN109071439B (zh) 2022-07-15
JP6780011B2 (ja) 2020-11-04
ES2806460T3 (es) 2021-02-17
JP2019511524A (ja) 2019-04-25
US11851388B2 (en) 2023-12-26
US20190119195A1 (en) 2019-04-25
EP3442944B1 (en) 2020-04-15
US20220002225A1 (en) 2022-01-06
BR112018070345B1 (pt) 2022-01-18
WO2017178868A1 (en) 2017-10-19
DK3442944T3 (da) 2020-07-13
US10640454B2 (en) 2020-05-05
CN109071439A (zh) 2018-12-21
US11148995B2 (en) 2021-10-19
HUE051536T2 (hu) 2021-03-01
US20200231533A1 (en) 2020-07-23
EP3442944A1 (en) 2019-02-20
PL3442944T3 (pl) 2020-09-21

Similar Documents

Publication Publication Date Title
CL2019003154A1 (es) Proceso de preparación de un compuesto intermediario de fórmula (vi) para la preparación de compuestos de cannabidiol. (divisional solicitud 201800079)
BR112018002499A2 (pt) método de preparação de um composto da fórmula (a) ou um seu sal, solvato ou conjugado de aminoácido farmaceuticamente aceitável, composto produzido pelo método e composição farmacêutica
SG11201806348PA (en) Steroid derivative fxr agonist
CU20180001A7 (es) Derivados de oxopiridina sustituidos y procesos para su preparación
CO2018000589A2 (es) Oxiesteroles y composiciones farmacéuticas que los contienen
EA201990833A1 (ru) Соединение пиридина
BR112018072246A2 (pt) síntese de indazóis
ZA201707152B (en) Methods for hydraulic enhancement of crops
UY36737A (es) 3-amino-1,5,6,7-tetrahidro-4h-indol-4-onas
BR112018070345A2 (pt) processo para a preparação de derivados de 4-aminoindano e amidas de aminoindano relacionadas
EA201991241A1 (ru) Способ получения метоксиметилпиридин дикарбоксилата
CL2020000376A1 (es) Compuesto pentacíclico.
BR112017019850A2 (pt) ?processo melhorado para a preparação de apremilast?
MY185367A (en) Improved process for the preparation of osimertinib (azd9291) or a salt thereof, and ?azd9291 aniline? or a salt thereof
EA201791645A1 (ru) Новые соли и полиморфы scy-078
BR112014018909A8 (pt) Compostos, processo para a preparação dos compostos, composição agroquímica, método para o combate dos fungos, utilização dos compostos e semente
PH12017501404A1 (en) Diaza-benzofluoranthrene compounds
EA201692368A1 (ru) Производные, полученные из гиалуроновой кислоты и карнозина
BR112018012325A2 (pt) métodos para a preparação de 5,6-di-hidro-6-fenilbenzo[f]isoquinolin-2-amina substituída
EA201991655A1 (ru) Тиобензоимидазолы в качестве фунгицидов
BR112016021910A2 (pt) Processo de preparação de 3-(3-(4-(1-aminociclobutil)fenil)-5-fenil-3h-imidazo[4,5-b]piridin-2-il)piridin-2-amina
BR112016022437A2 (pt) Processo para preparação de (2s,5r)-6-(benziloxi)-7-oxo-1,6- diazabiciclo[3,2,1]octano-2-carboxilato de sódio
EA201990313A1 (ru) Производное триазолопиразинона, пригодное в качестве ингибитора фдэ1 человека
EA201792109A1 (ru) Конденсированные с тетрагидрофураном производные аминогидротиазина, пригодные для лечения болезни альцгеймера
AR101951A1 (es) Síntesis de ent-progesterona e intermediarios de la misma

Legal Events

Date Code Title Description
B06U Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette]
B350 Update of information on the portal [chapter 15.35 patent gazette]
B09A Decision: intention to grant [chapter 9.1 patent gazette]
B16A Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]

Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 15/04/2016, OBSERVADAS AS CONDICOES LEGAIS.

B25A Requested transfer of rights approved

Owner name: FMC AGRICULTURAL PRODUCTS INTERNATIONAL AG (CH)