BR112018016110A2 - gerador de aerossol, nebulizador e método de fabricação de um gerador de aerossol - Google Patents
gerador de aerossol, nebulizador e método de fabricação de um gerador de aerossolInfo
- Publication number
- BR112018016110A2 BR112018016110A2 BR112018016110A BR112018016110A BR112018016110A2 BR 112018016110 A2 BR112018016110 A2 BR 112018016110A2 BR 112018016110 A BR112018016110 A BR 112018016110A BR 112018016110 A BR112018016110 A BR 112018016110A BR 112018016110 A2 BR112018016110 A2 BR 112018016110A2
- Authority
- BR
- Brazil
- Prior art keywords
- nebulizer
- aerosol generator
- air stream
- water
- encapsulation
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M11/00—Sprayers or atomisers specially adapted for therapeutic purposes
- A61M11/005—Sprayers or atomisers specially adapted for therapeutic purposes using ultrasonics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/0085—Inhalators using ultrasonics
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B05—SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
- B05B—SPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
- B05B17/00—Apparatus for spraying or atomising liquids or other fluent materials, not covered by the preceding groups
- B05B17/04—Apparatus for spraying or atomising liquids or other fluent materials, not covered by the preceding groups operating with special methods
- B05B17/06—Apparatus for spraying or atomising liquids or other fluent materials, not covered by the preceding groups operating with special methods using ultrasonic or other kinds of vibrations
- B05B17/0607—Apparatus for spraying or atomising liquids or other fluent materials, not covered by the preceding groups operating with special methods using ultrasonic or other kinds of vibrations generated by electrical means, e.g. piezoelectric transducers
- B05B17/0638—Apparatus for spraying or atomising liquids or other fluent materials, not covered by the preceding groups operating with special methods using ultrasonic or other kinds of vibrations generated by electrical means, e.g. piezoelectric transducers spray being produced by discharging the liquid or other fluent material through a plate comprising a plurality of orifices
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B05—SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
- B05B—SPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
- B05B17/00—Apparatus for spraying or atomising liquids or other fluent materials, not covered by the preceding groups
- B05B17/04—Apparatus for spraying or atomising liquids or other fluent materials, not covered by the preceding groups operating with special methods
- B05B17/06—Apparatus for spraying or atomising liquids or other fluent materials, not covered by the preceding groups operating with special methods using ultrasonic or other kinds of vibrations
- B05B17/0607—Apparatus for spraying or atomising liquids or other fluent materials, not covered by the preceding groups operating with special methods using ultrasonic or other kinds of vibrations generated by electrical means, e.g. piezoelectric transducers
- B05B17/0653—Details
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B05—SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
- B05B—SPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
- B05B17/00—Apparatus for spraying or atomising liquids or other fluent materials, not covered by the preceding groups
- B05B17/04—Apparatus for spraying or atomising liquids or other fluent materials, not covered by the preceding groups operating with special methods
- B05B17/06—Apparatus for spraying or atomising liquids or other fluent materials, not covered by the preceding groups operating with special methods using ultrasonic or other kinds of vibrations
- B05B17/0607—Apparatus for spraying or atomising liquids or other fluent materials, not covered by the preceding groups operating with special methods using ultrasonic or other kinds of vibrations generated by electrical means, e.g. piezoelectric transducers
- B05B17/0638—Apparatus for spraying or atomising liquids or other fluent materials, not covered by the preceding groups operating with special methods using ultrasonic or other kinds of vibrations generated by electrical means, e.g. piezoelectric transducers spray being produced by discharging the liquid or other fluent material through a plate comprising a plurality of orifices
- B05B17/0646—Vibrating plates, i.e. plates being directly subjected to the vibrations, e.g. having a piezoelectric transducer attached thereto
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Anesthesiology (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Hematology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pulmonology (AREA)
- Special Spraying Apparatus (AREA)
- Medicinal Preparation (AREA)
Abstract
trata-se de nebulizadores que são usados para fornecer um medicamento aos pulmões de um paciente sob a forma de uma corrente de ar, com fluido compreendendo o medicamento arrastado na corrente de ar. para possibilitar que o fluido seja arrastado na corrente de ar, um nebulizador contém um gerador de aerossol que compreende, tipicamente, um elemento vibratório (28) com um atuador piezoelétrico. existe uma necessidade de esterilizar frequentemente o nebulizador. isso envolve a imersão do nebulizador em água fervente durante um tempo significativo. descobriu-se que ciclos de esterilização repetidos podem forçar a água através de vãos no elemento vibratório, e sua encapsulação (26), e danificar o elemento piezo. a presente invenção propõe vedar mais eficazmente o piezo do elemento vibratório (28) contra os efeitos do ingresso de água. em particular, é proposto criar, em uma interface do elemento vibratório (28) e do elemento de encapsulação (26), uma descontinuidade que fornece uma geometria de barreira. através de forças capilares, o avanço da água em direção ao elemento piezelétrico (12) compreendido no elemento vibratório (28) é detido, e o tempo de vida do gerador de aerossol é aprimorado.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP16154653 | 2016-02-08 | ||
EP16154653.6 | 2016-02-08 | ||
PCT/EP2017/051453 WO2017137252A1 (en) | 2016-02-08 | 2017-01-25 | An aerosol generator |
Publications (2)
Publication Number | Publication Date |
---|---|
BR112018016110A2 true BR112018016110A2 (pt) | 2019-01-02 |
BR112018016110B1 BR112018016110B1 (pt) | 2023-01-24 |
Family
ID=55345711
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR112018016110-1A BR112018016110B1 (pt) | 2016-02-08 | 2017-01-25 | Gerador de aerossol, nebulizador e método de fabricação de um gerador de aerossol |
Country Status (6)
Country | Link |
---|---|
US (1) | US11376375B2 (pt) |
EP (1) | EP3413959B1 (pt) |
JP (1) | JP7084309B2 (pt) |
CN (1) | CN108601915B (pt) |
BR (1) | BR112018016110B1 (pt) |
WO (1) | WO2017137252A1 (pt) |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP3127616B1 (en) * | 2015-08-03 | 2017-10-18 | PARI Pharma GmbH | Method of manufacturing a vibratable head for an aerosol generator and vibratable head for an aerosol generator |
EP3950141A1 (en) * | 2017-12-14 | 2022-02-09 | Stamford Devices Limited | Mounting of an aerosol generator aperture plate to a support |
MX2020012960A (es) * | 2018-05-31 | 2021-04-28 | Vapotherm Inc | Nebulizador de malla vibratoria basado en canula. |
GB2579569B (en) * | 2018-12-03 | 2023-08-02 | Ttp Plc | Liquid droplet production apparatus |
US11992851B2 (en) * | 2018-12-12 | 2024-05-28 | Shl Medical Ag | Aerosol unit |
CN114728147A (zh) | 2019-09-26 | 2022-07-08 | 蒸汽热能公司 | 插管内部安装的雾化器 |
Family Cites Families (31)
Publication number | Priority date | Publication date | Assignee | Title |
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US709848A (en) | 1901-11-18 | 1902-09-23 | John L Creveling | Combined dynamo and driving-gear. |
JPS5913264B2 (ja) * | 1978-05-04 | 1984-03-28 | 松下電器産業株式会社 | 超音波液体霧化装置 |
US4850534A (en) | 1987-05-30 | 1989-07-25 | Tdk Corporation | Ultrasonic wave nebulizer |
JP2772319B2 (ja) * | 1992-07-13 | 1998-07-02 | 矢崎総業株式会社 | コネクタのシール構造 |
US6014970A (en) * | 1998-06-11 | 2000-01-18 | Aerogen, Inc. | Methods and apparatus for storing chemical compounds in a portable inhaler |
US6205999B1 (en) | 1995-04-05 | 2001-03-27 | Aerogen, Inc. | Methods and apparatus for storing chemical compounds in a portable inhaler |
DE19847923C1 (de) * | 1998-10-19 | 2000-03-02 | Smr Stiegler Maschinenfabrik G | Ablegeeinrichtung für Bahnabschnitte aus Folienmaterial |
US20070044792A1 (en) | 2005-08-30 | 2007-03-01 | Aerogen, Inc. | Aerosol generators with enhanced corrosion resistance |
EP1509259B1 (en) * | 2002-05-20 | 2016-04-20 | Novartis AG | Apparatus for providing aerosol for medical treatment and methods |
JP3885744B2 (ja) | 2003-02-25 | 2007-02-28 | 株式会社デンソー | ノックセンサ |
JP4661142B2 (ja) | 2004-09-14 | 2011-03-30 | 富士ゼロックス株式会社 | カラー画像形成装置 |
TWI268179B (en) | 2005-04-12 | 2006-12-11 | Ind Tech Res Inst | Improved structure of atomizing nozzle the plate can be vibrated by the vibrator element to compress the fluid, so that the fluid is jet from the perforations in form of tiny particle |
US9108211B2 (en) | 2005-05-25 | 2015-08-18 | Nektar Therapeutics | Vibration systems and methods |
ES2360634T3 (es) * | 2006-04-05 | 2011-06-07 | Microdose Therapeutx, Inc. | Dispositivo de inhalación de dosis variables. |
EP1952896B1 (en) | 2007-02-01 | 2012-11-07 | EP Systems SA | Droplet dispenser |
EP1977778A1 (en) | 2007-04-06 | 2008-10-08 | Markos Mefar S.P.A. | Electronic nebulizer for washing the nasal cavities of a user |
US20090242660A1 (en) * | 2008-03-25 | 2009-10-01 | Quatek Co., Ltd. | Medical liquid droplet apparatus |
CN201200951Y (zh) * | 2008-06-05 | 2009-03-04 | 刘淑芹 | 一种压电桥式梁驱动的液体喷射结构 |
JP5154658B2 (ja) | 2008-10-24 | 2013-02-27 | パナソニック株式会社 | 弾性表面波霧化装置 |
WO2010089822A1 (ja) | 2009-02-09 | 2010-08-12 | 株式会社村田製作所 | 霧化部材及びそれを備える霧化器 |
EP2982445B1 (en) * | 2010-10-04 | 2019-03-13 | Stamford Devices Limited | An aerosol generator |
MX348852B (es) | 2011-09-19 | 2017-07-03 | Koninklijke Philips Nv | Nebulizador, unidad de control que controla el mismo, elemento de nebulizacion y metodo de operación del nebulizador. |
JP5652790B2 (ja) * | 2011-09-22 | 2015-01-14 | オムロンヘルスケア株式会社 | 液体噴霧装置 |
DE102012204302A1 (de) * | 2012-03-19 | 2013-09-19 | Robert Bosch Gmbh | Umspritztes Bauelement mit einem Dichtlabyrinth |
JP2013230109A (ja) * | 2012-04-27 | 2013-11-14 | Sumitomo Chemical Co Ltd | 超音波霧化装置 |
TWM450428U (zh) * | 2012-10-19 | 2013-04-11 | Microbase Technology Corp | 噴孔片改良之霧化裝置 |
JP5913264B2 (ja) * | 2013-11-19 | 2016-04-27 | リンナイ株式会社 | 暖房機 |
RU2676981C1 (ru) | 2013-12-19 | 2019-01-14 | Конинклейке Филипс Н.В. | Устройство для образования капель жидкости |
EP2886185A1 (en) | 2013-12-20 | 2015-06-24 | Activaero GmbH | Perforated membrane and process for its preparation |
CN204709559U (zh) * | 2015-05-04 | 2015-10-21 | 德技股份有限公司 | 雾化器 |
DE202015102538U1 (de) | 2015-05-19 | 2015-07-30 | Quatek Holding Inc. | Atomizer |
-
2017
- 2017-01-25 US US16/076,341 patent/US11376375B2/en active Active
- 2017-01-25 WO PCT/EP2017/051453 patent/WO2017137252A1/en active Application Filing
- 2017-01-25 CN CN201780010237.XA patent/CN108601915B/zh active Active
- 2017-01-25 JP JP2018540850A patent/JP7084309B2/ja active Active
- 2017-01-25 BR BR112018016110-1A patent/BR112018016110B1/pt active IP Right Grant
- 2017-01-25 EP EP17701855.3A patent/EP3413959B1/en active Active
Also Published As
Publication number | Publication date |
---|---|
EP3413959B1 (en) | 2020-06-17 |
CN108601915B (zh) | 2021-09-21 |
US11376375B2 (en) | 2022-07-05 |
WO2017137252A1 (en) | 2017-08-17 |
CN108601915A (zh) | 2018-09-28 |
BR112018016110B1 (pt) | 2023-01-24 |
US20190038851A1 (en) | 2019-02-07 |
EP3413959A1 (en) | 2018-12-19 |
JP7084309B2 (ja) | 2022-06-14 |
JP2019503816A (ja) | 2019-02-14 |
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Legal Events
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B06W | Patent application suspended after preliminary examination (for patents with searches from other patent authorities) chapter 6.23 patent gazette] | ||
B09A | Decision: intention to grant [chapter 9.1 patent gazette] | ||
B16A | Patent or certificate of addition of invention granted [chapter 16.1 patent gazette] |
Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 25/01/2017, OBSERVADAS AS CONDICOES LEGAIS |