BR112018013242A2 - dispositivo de eletroporação com gerador de sinal melhorado - Google Patents
dispositivo de eletroporação com gerador de sinal melhoradoInfo
- Publication number
- BR112018013242A2 BR112018013242A2 BR112018013242-0A BR112018013242A BR112018013242A2 BR 112018013242 A2 BR112018013242 A2 BR 112018013242A2 BR 112018013242 A BR112018013242 A BR 112018013242A BR 112018013242 A2 BR112018013242 A2 BR 112018013242A2
- Authority
- BR
- Brazil
- Prior art keywords
- signal generator
- electroporation device
- improved signal
- secondary windings
- primary winding
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/02—Details
- A61N1/025—Digital circuitry features of electrotherapy devices, e.g. memory, clocks, processors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/02—Details
- A61N1/04—Electrodes
- A61N1/0404—Electrodes for external use
- A61N1/0408—Use-related aspects
- A61N1/0412—Specially adapted for transcutaneous electroporation, e.g. including drug reservoirs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/02—Details
- A61N1/04—Electrodes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/02—Details
- A61N1/08—Arrangements or circuits for monitoring, protecting, controlling or indicating
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/20—Applying electric currents by contact electrodes continuous direct currents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
- A61N1/325—Applying electric currents by contact electrodes alternating or intermittent currents for iontophoresis, i.e. transfer of media in ionic state by an electromotoric force into the body
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
- A61N1/327—Applying electric currents by contact electrodes alternating or intermittent currents for enhancing the absorption properties of tissue, e.g. by electroporation
-
- H—ELECTRICITY
- H02—GENERATION; CONVERSION OR DISTRIBUTION OF ELECTRIC POWER
- H02M—APPARATUS FOR CONVERSION BETWEEN AC AND AC, BETWEEN AC AND DC, OR BETWEEN DC AND DC, AND FOR USE WITH MAINS OR SIMILAR POWER SUPPLY SYSTEMS; CONVERSION OF DC OR AC INPUT POWER INTO SURGE OUTPUT POWER; CONTROL OR REGULATION THEREOF
- H02M1/00—Details of apparatus for conversion
- H02M1/0067—Converter structures employing plural converter units, other than for parallel operation of the units on a single load
- H02M1/0077—Plural converter units whose outputs are connected in series
-
- H—ELECTRICITY
- H02—GENERATION; CONVERSION OR DISTRIBUTION OF ELECTRIC POWER
- H02M—APPARATUS FOR CONVERSION BETWEEN AC AND AC, BETWEEN AC AND DC, OR BETWEEN DC AND DC, AND FOR USE WITH MAINS OR SIMILAR POWER SUPPLY SYSTEMS; CONVERSION OF DC OR AC INPUT POWER INTO SURGE OUTPUT POWER; CONTROL OR REGULATION THEREOF
- H02M11/00—Power conversion systems not covered by the preceding groups
-
- H—ELECTRICITY
- H02—GENERATION; CONVERSION OR DISTRIBUTION OF ELECTRIC POWER
- H02M—APPARATUS FOR CONVERSION BETWEEN AC AND AC, BETWEEN AC AND DC, OR BETWEEN DC AND DC, AND FOR USE WITH MAINS OR SIMILAR POWER SUPPLY SYSTEMS; CONVERSION OF DC OR AC INPUT POWER INTO SURGE OUTPUT POWER; CONTROL OR REGULATION THEREOF
- H02M3/00—Conversion of dc power input into dc power output
- H02M3/22—Conversion of dc power input into dc power output with intermediate conversion into ac
- H02M3/24—Conversion of dc power input into dc power output with intermediate conversion into ac by static converters
-
- H—ELECTRICITY
- H02—GENERATION; CONVERSION OR DISTRIBUTION OF ELECTRIC POWER
- H02M—APPARATUS FOR CONVERSION BETWEEN AC AND AC, BETWEEN AC AND DC, OR BETWEEN DC AND DC, AND FOR USE WITH MAINS OR SIMILAR POWER SUPPLY SYSTEMS; CONVERSION OF DC OR AC INPUT POWER INTO SURGE OUTPUT POWER; CONTROL OR REGULATION THEREOF
- H02M3/00—Conversion of dc power input into dc power output
- H02M3/22—Conversion of dc power input into dc power output with intermediate conversion into ac
- H02M3/24—Conversion of dc power input into dc power output with intermediate conversion into ac by static converters
- H02M3/28—Conversion of dc power input into dc power output with intermediate conversion into ac by static converters using discharge tubes with control electrode or semiconductor devices with control electrode to produce the intermediate ac
- H02M3/325—Conversion of dc power input into dc power output with intermediate conversion into ac by static converters using discharge tubes with control electrode or semiconductor devices with control electrode to produce the intermediate ac using devices of a triode or a transistor type requiring continuous application of a control signal
- H02M3/335—Conversion of dc power input into dc power output with intermediate conversion into ac by static converters using discharge tubes with control electrode or semiconductor devices with control electrode to produce the intermediate ac using devices of a triode or a transistor type requiring continuous application of a control signal using semiconductor devices only
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Biomedical Technology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Radiology & Medical Imaging (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Power Engineering (AREA)
- Biophysics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Heart & Thoracic Surgery (AREA)
- Neurology (AREA)
- Electrotherapy Devices (AREA)
- Amplifiers (AREA)
- Circuits Of Receivers In General (AREA)
- Measurement And Recording Of Electrical Phenomena And Electrical Characteristics Of The Living Body (AREA)
- Dc-Dc Converters (AREA)
- Charge And Discharge Circuits For Batteries Or The Like (AREA)
- Meter Arrangements (AREA)
- Electromechanical Clocks (AREA)
- Media Introduction/Drainage Providing Device (AREA)
Abstract
um aparelho portátil para um dispositivo de eletroporação com um gerador de sinal melhorado. o gerador de sinal inclui um enrolamento primário e uma pluralidade de enrolamentos secundários onde a pluralidade de enrolamentos secundários é acoplada em conjunto em uma configuração em série. um condensador de armazenamento e o diodo fly-back são acoplados a cada um da pluralidade de enrolamentos secundários. o gerador de sinal inclui um amplificador de sinal e um interruptor de potência. o interruptor de potência está configurado para fornecer uma tensão de uma fonte de alimentação através do enrolamento primário.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201562271955P | 2015-12-28 | 2015-12-28 | |
US62/271,955 | 2015-12-28 | ||
PCT/US2016/068940 WO2017117251A1 (en) | 2015-12-28 | 2016-12-28 | Electroporation device with improved signal generator |
Publications (2)
Publication Number | Publication Date |
---|---|
BR112018013242A2 true BR112018013242A2 (pt) | 2018-12-04 |
BR112018013242B1 BR112018013242B1 (pt) | 2023-10-10 |
Family
ID=59225638
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR112018013242-0A BR112018013242B1 (pt) | 2015-12-28 | 2016-12-28 | Dispositivo de eletroporação com gerador de sinal melhorado |
Country Status (18)
Country | Link |
---|---|
US (1) | US20190009081A1 (pt) |
EP (2) | EP4098315A1 (pt) |
JP (2) | JP7025332B2 (pt) |
KR (1) | KR20180099747A (pt) |
CN (2) | CN108472482B (pt) |
AU (1) | AU2016382944B2 (pt) |
BR (1) | BR112018013242B1 (pt) |
CA (1) | CA3009347A1 (pt) |
DK (1) | DK3397335T3 (pt) |
ES (1) | ES2929478T3 (pt) |
HU (1) | HUE060331T2 (pt) |
IL (2) | IL300103A (pt) |
MX (2) | MX2018008003A (pt) |
PL (1) | PL3397335T3 (pt) |
PT (1) | PT3397335T (pt) |
RU (2) | RU2737328C2 (pt) |
SG (1) | SG11201805315RA (pt) |
WO (1) | WO2017117251A1 (pt) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IT202100004601A1 (it) | 2021-02-26 | 2022-08-26 | Igea S P A | Generatore di impulsi ad alta tensione per elettroporazione |
Family Cites Families (22)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5439440A (en) * | 1993-04-01 | 1995-08-08 | Genetronics, Inc. | Electroporation system with voltage control feedback for clinical applications |
US6369893B1 (en) * | 1998-05-19 | 2002-04-09 | Cepheid | Multi-channel optical detection system |
US6150148A (en) * | 1998-10-21 | 2000-11-21 | Genetronics, Inc. | Electroporation apparatus for control of temperature during the process |
US7127285B2 (en) * | 1999-03-12 | 2006-10-24 | Transport Pharmaceuticals Inc. | Systems and methods for electrokinetic delivery of a substance |
US6118679A (en) * | 1999-04-26 | 2000-09-12 | Astec International, Limited | Current sharing transformer circuit for power converters |
US7010343B2 (en) * | 2001-04-06 | 2006-03-07 | Mattioli Engineering Ltd. | Method and apparatus for skin absorption enhancement and transdermal drug delivery |
US6603352B2 (en) * | 2001-12-03 | 2003-08-05 | Icefyre Semiconductor Corporation | Switched-mode power amplifier integrally performing power combining |
US20060034943A1 (en) * | 2003-10-31 | 2006-02-16 | Technology Innovations Llc | Process for treating a biological organism |
EP1727257A1 (en) * | 2005-05-25 | 2006-11-29 | ABB Sp.zo.o. | A protection circuit for potential transformers |
US7449841B2 (en) * | 2006-04-24 | 2008-11-11 | Microsemi Corp.—Analog Mixed Signal Group Ltd. | Charge limited high voltage switch circuits |
KR101188944B1 (ko) * | 2006-06-15 | 2012-10-08 | 한국과학기술원 | 다중 변압기의 2차 권선을 병렬로 연결한 전하 균일 장치 |
US7816894B2 (en) * | 2006-06-23 | 2010-10-19 | Electro-Chance, Llc | Method and apparatus for regulating voltage |
WO2008118393A1 (en) * | 2007-03-23 | 2008-10-02 | University Of Southern California | Compact subnanosecond high voltage pulse generation system for cell electro-manipulation |
JP2010529897A (ja) * | 2007-06-15 | 2010-09-02 | ニトリツク・バイオ・セラピユーテイクス・インコーポレーテツド | 動電学的薬剤配送の電流集中緩和方法とシステム |
US8398627B2 (en) * | 2008-05-23 | 2013-03-19 | Gyrus Medical Limited | Electrosurgical generator and system |
ES2788098T3 (es) * | 2009-12-14 | 2020-10-20 | Leach Int Corporation | Sistemas y métodos para equilibrar baterías multicelda |
CN201766514U (zh) * | 2010-08-26 | 2011-03-16 | 珠海金电电源工业有限公司 | 一种大功率高电压输出电路 |
CN102447395A (zh) * | 2011-12-30 | 2012-05-09 | 深圳麦格米特电气股份有限公司 | 一种多电平平衡电路的实现方法和多电平平衡电路 |
EP2911736A4 (en) * | 2012-10-25 | 2016-06-15 | Oncosec Medical Inc | electroporation |
US9318978B2 (en) * | 2013-09-30 | 2016-04-19 | Infineon Technologies Austria Ag | Voltage converter with soft communication networks |
JP2015204735A (ja) * | 2014-04-16 | 2015-11-16 | シャープ株式会社 | スイッチング回路、およびスイッチング電源装置 |
CN203984266U (zh) * | 2014-07-17 | 2014-12-03 | 广东易事特电源股份有限公司 | 一种高压开关电源 |
-
2016
- 2016-12-28 CN CN201680076947.8A patent/CN108472482B/zh active Active
- 2016-12-28 RU RU2018127473A patent/RU2737328C2/ru active
- 2016-12-28 WO PCT/US2016/068940 patent/WO2017117251A1/en active Application Filing
- 2016-12-28 BR BR112018013242-0A patent/BR112018013242B1/pt active IP Right Grant
- 2016-12-28 EP EP22187994.3A patent/EP4098315A1/en active Pending
- 2016-12-28 US US16/066,959 patent/US20190009081A1/en active Pending
- 2016-12-28 ES ES16882581T patent/ES2929478T3/es active Active
- 2016-12-28 SG SG11201805315RA patent/SG11201805315RA/en unknown
- 2016-12-28 AU AU2016382944A patent/AU2016382944B2/en active Active
- 2016-12-28 KR KR1020187020985A patent/KR20180099747A/ko not_active Application Discontinuation
- 2016-12-28 PL PL16882581.8T patent/PL3397335T3/pl unknown
- 2016-12-28 CA CA3009347A patent/CA3009347A1/en active Pending
- 2016-12-28 HU HUE16882581A patent/HUE060331T2/hu unknown
- 2016-12-28 IL IL300103A patent/IL300103A/en unknown
- 2016-12-28 JP JP2018534062A patent/JP7025332B2/ja active Active
- 2016-12-28 PT PT168825818T patent/PT3397335T/pt unknown
- 2016-12-28 DK DK16882581.8T patent/DK3397335T3/da active
- 2016-12-28 MX MX2018008003A patent/MX2018008003A/es unknown
- 2016-12-28 EP EP16882581.8A patent/EP3397335B1/en active Active
- 2016-12-28 CN CN202210582114.6A patent/CN115068812A/zh active Pending
-
2018
- 2018-06-17 IL IL260073A patent/IL260073B2/en unknown
- 2018-06-27 MX MX2022007014A patent/MX2022007014A/es unknown
-
2020
- 2020-11-23 RU RU2020138264A patent/RU2750970C1/ru active
-
2022
- 2022-02-10 JP JP2022019337A patent/JP2022051934A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
AU2016382944B2 (en) | 2022-01-27 |
BR112018013242B1 (pt) | 2023-10-10 |
PL3397335T3 (pl) | 2023-02-13 |
MX2022007014A (es) | 2022-06-17 |
CA3009347A1 (en) | 2017-07-06 |
JP7025332B2 (ja) | 2022-02-24 |
DK3397335T3 (da) | 2022-11-07 |
RU2737328C2 (ru) | 2020-11-27 |
SG11201805315RA (en) | 2018-07-30 |
WO2017117251A1 (en) | 2017-07-06 |
ES2929478T3 (es) | 2022-11-29 |
EP3397335B1 (en) | 2022-08-03 |
IL300103A (en) | 2023-03-01 |
EP4098315A1 (en) | 2022-12-07 |
RU2018127473A3 (pt) | 2020-05-13 |
AU2016382944A1 (en) | 2018-07-12 |
PT3397335T (pt) | 2022-11-21 |
MX2018008003A (es) | 2019-03-28 |
JP2019500151A (ja) | 2019-01-10 |
KR20180099747A (ko) | 2018-09-05 |
CN108472482A (zh) | 2018-08-31 |
IL260073A (en) | 2018-07-31 |
EP3397335A1 (en) | 2018-11-07 |
CN115068812A (zh) | 2022-09-20 |
AU2022202761A1 (en) | 2022-05-19 |
EP3397335A4 (en) | 2018-12-26 |
US20190009081A1 (en) | 2019-01-10 |
RU2018127473A (ru) | 2020-01-30 |
JP2022051934A (ja) | 2022-04-01 |
HUE060331T2 (hu) | 2023-02-28 |
CN108472482B (zh) | 2022-06-14 |
RU2750970C1 (ru) | 2021-07-07 |
IL260073B2 (en) | 2023-06-01 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
B06U | Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette] | ||
B09A | Decision: intention to grant [chapter 9.1 patent gazette] | ||
B16A | Patent or certificate of addition of invention granted [chapter 16.1 patent gazette] |
Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 28/12/2016, OBSERVADAS AS CONDICOES LEGAIS |