BR112017021505A2 - produção de vetores adenoassociados superdimensionados - Google Patents

produção de vetores adenoassociados superdimensionados

Info

Publication number
BR112017021505A2
BR112017021505A2 BR112017021505A BR112017021505A BR112017021505A2 BR 112017021505 A2 BR112017021505 A2 BR 112017021505A2 BR 112017021505 A BR112017021505 A BR 112017021505A BR 112017021505 A BR112017021505 A BR 112017021505A BR 112017021505 A2 BR112017021505 A2 BR 112017021505A2
Authority
BR
Brazil
Prior art keywords
oversized
adeno
aav
production
associated vectors
Prior art date
Application number
BR112017021505A
Other languages
English (en)
Portuguese (pt)
Inventor
Souza David
Vincent Karen
Kyostio-Moore Sirkka
Original Assignee
Genzyme Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=56943906&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BR112017021505(A2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Genzyme Corp filed Critical Genzyme Corp
Publication of BR112017021505A2 publication Critical patent/BR112017021505A2/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/1703—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • A61K38/1709—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/745—Blood coagulation or fibrinolysis factors
    • C07K14/755—Factors VIII, e.g. factor VIII C (AHF), factor VIII Ag (VWF)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/86—Viral vectors
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/10011—Adenoviridae
    • C12N2710/10041—Use of virus, viral particle or viral elements as a vector
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2750/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssDNA viruses
    • C12N2750/00011—Details
    • C12N2750/14011—Parvoviridae
    • C12N2750/14111—Dependovirus, e.g. adenoassociated viruses
    • C12N2750/14141—Use of virus, viral particle or viral elements as a vector
    • C12N2750/14143—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2750/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssDNA viruses
    • C12N2750/00011—Details
    • C12N2750/14011—Parvoviridae
    • C12N2750/14111—Dependovirus, e.g. adenoassociated viruses
    • C12N2750/14151—Methods of production or purification of viral material
    • C12N2750/14152—Methods of production or purification of viral material relating to complementing cells and packaging systems for producing virus or viral particles

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • General Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Virology (AREA)
  • Molecular Biology (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Toxicology (AREA)
  • Hematology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Epidemiology (AREA)
  • Marine Sciences & Fisheries (AREA)
  • Neurology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Pulmonology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
BR112017021505A 2015-04-08 2016-04-07 produção de vetores adenoassociados superdimensionados BR112017021505A2 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201562144862P 2015-04-08 2015-04-08
US201562220067P 2015-09-17 2015-09-17
PCT/US2016/026486 WO2016164609A2 (en) 2015-04-08 2016-04-07 Production of oversized adeno-associated vectors

Publications (1)

Publication Number Publication Date
BR112017021505A2 true BR112017021505A2 (pt) 2018-07-03

Family

ID=56943906

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112017021505A BR112017021505A2 (pt) 2015-04-08 2016-04-07 produção de vetores adenoassociados superdimensionados

Country Status (27)

Country Link
US (1) US10815497B2 (https=)
EP (2) EP3280799B1 (https=)
JP (3) JP6878299B2 (https=)
KR (2) KR20250126875A (https=)
CN (1) CN107864657A (https=)
AU (3) AU2016245806A1 (https=)
BR (1) BR112017021505A2 (https=)
CA (1) CA2982123A1 (https=)
CL (1) CL2017002537A1 (https=)
CO (1) CO2017011344A2 (https=)
CR (1) CR20170505A (https=)
DK (1) DK3280799T3 (https=)
EA (1) EA201792236A1 (https=)
EC (1) ECSP17074016A (https=)
ES (1) ES3008382T3 (https=)
GT (1) GT201700214A (https=)
HU (1) HUE069779T2 (https=)
IL (3) IL283291B (https=)
MX (1) MX2017012935A (https=)
PE (1) PE20171800A1 (https=)
PH (1) PH12017501836A1 (https=)
PL (1) PL3280799T3 (https=)
SG (3) SG10201912912QA (https=)
TN (1) TN2017000431A1 (https=)
TW (1) TWI707951B (https=)
UY (1) UY36611A (https=)
WO (1) WO2016164609A2 (https=)

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Also Published As

Publication number Publication date
TW201710498A (zh) 2017-03-16
WO2016164609A3 (en) 2016-12-15
ES3008382T3 (en) 2025-03-24
MX2017012935A (es) 2018-02-12
PH12017501836A1 (en) 2018-04-23
JP2023116678A (ja) 2023-08-22
KR20170133500A (ko) 2017-12-05
EP4512429A3 (en) 2025-05-21
IL283291A (en) 2021-07-29
AU2022203942B2 (en) 2023-12-14
IL254933B (en) 2021-06-30
NZ737009A (en) 2024-01-26
SG10201909381WA (en) 2019-11-28
CL2017002537A1 (es) 2018-05-11
SG11201708203UA (en) 2017-11-29
IL254933A0 (en) 2017-12-31
KR20250126875A (ko) 2025-08-25
EP3280799B1 (en) 2024-10-30
CA2982123A1 (en) 2016-10-13
AU2022203942A1 (en) 2022-06-23
HUE069779T2 (hu) 2025-04-28
TWI707951B (zh) 2020-10-21
US10815497B2 (en) 2020-10-27
UY36611A (es) 2016-11-30
GT201700214A (es) 2018-10-24
AU2016245806A1 (en) 2017-11-30
IL283291B (en) 2022-08-01
EP3280799A2 (en) 2018-02-14
JP6878299B2 (ja) 2021-05-26
SG10201912912QA (en) 2020-02-27
HK1246339A1 (en) 2018-09-07
IL294965A (en) 2022-09-01
JP2021118724A (ja) 2021-08-12
WO2016164609A2 (en) 2016-10-13
TN2017000431A1 (en) 2019-04-12
AU2024201619A1 (en) 2024-03-28
CO2017011344A2 (es) 2018-03-28
PE20171800A1 (es) 2017-12-28
CR20170505A (es) 2018-01-26
JP2018510648A (ja) 2018-04-19
CN107864657A (zh) 2018-03-30
US20190048362A1 (en) 2019-02-14
EP4512429A2 (en) 2025-02-26
PL3280799T3 (pl) 2025-04-14
NZ774736A (en) 2024-08-30
KR102848324B1 (ko) 2025-08-20
DK3280799T3 (da) 2025-01-27
ECSP17074016A (es) 2018-02-28
EA201792236A1 (ru) 2018-03-30

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