BR112017015958A2 - material de base transdermicamente absorvível contendo composto lípido-péptido - Google Patents

material de base transdermicamente absorvível contendo composto lípido-péptido

Info

Publication number
BR112017015958A2
BR112017015958A2 BR112017015958-9A BR112017015958A BR112017015958A2 BR 112017015958 A2 BR112017015958 A2 BR 112017015958A2 BR 112017015958 A BR112017015958 A BR 112017015958A BR 112017015958 A2 BR112017015958 A2 BR 112017015958A2
Authority
BR
Brazil
Prior art keywords
group
base material
optionally
membered cyclic
peptide compound
Prior art date
Application number
BR112017015958-9A
Other languages
English (en)
Japanese (ja)
Inventor
Goto Masahiro
Miyachi Nobuhide
Iwama Takehisa
Imoto Takayuki
Original Assignee
Nissan Chemical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nissan Chemical Industries Ltd filed Critical Nissan Chemical Industries Ltd
Publication of BR112017015958A2 publication Critical patent/BR112017015958A2/pt

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/726—Glycosaminoglycans, i.e. mucopolysaccharides
    • A61K31/728—Hyaluronic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/28—Insulins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12—Carboxylic acids; Salts or anhydrides thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A61K47/183—Amino acids, e.g. glycine, EDTA or aspartame
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/42—Proteins; Polypeptides; Degradation products thereof; Derivatives thereof, e.g. albumin, gelatin or zein
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
    • A61K8/0216—Solid or semisolid forms
    • A61K8/0229—Sticks
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/34—Alcohols
    • A61K8/345—Alcohols containing more than one hydroxy group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/36—Carboxylic acids; Salts or anhydrides thereof
    • A61K8/361—Carboxylic acids having more than seven carbon atoms in an unbroken chain; Salts or anhydrides thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/60—Sugars; Derivatives thereof
    • A61K8/608—Derivatives containing from 2 to 10 oxyalkylene groups
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/10—General cosmetic use

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Birds (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Dermatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Emergency Medicine (AREA)
  • Molecular Biology (AREA)
  • Inorganic Chemistry (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • Endocrinology (AREA)
  • Diabetes (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Cosmetics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

é provido um material de base transdermicamente absorvível compreendendo um composto lípido-péptido que usa um gelador de baixo peso molecular para melhorar não apenas a sensibilidade de uso, mas também a capacidade de absorção transdérmica. material de base transdermicamente absorvível, compreende um composto lípido-péptido incluindo pelo menos um composto do fórmula (1) abaixo e os compostos similares ou seus sais farmaceuticamente utilizáveis, um surfactante, um álcool poli-hídrico específico; um ácido graxo e água, formula (1) em que r1 é um grupo alifático c9-23; r2 é um átomo de hidrogénio ou um grupo alquilo c1-4 que possui opcionalmente uma cadeia ramificada com um número de átomos de carbono de 1 ou 2; r3 é um grupo - (ch2)n-x; n é um número de 1 a 4; e x é grupo amino, grupo guanidino, grupo -conh2 ou um grupo cíclico de 5 membros possuindo opcionalmente 1 a 3 átomos de nitrogênio, um grupo cíclico de 6 membros possuindo opcionalmente 1 a 3 átomos de nitrogênio ou um grupo heterocíclico condensado constituído por um grupo cíclico de 5 membros e um grupo cíclico de 6 membros que opcionalmente possui 1 a 3 átomos de nitrogênio.
BR112017015958-9A 2015-01-28 2016-01-28 material de base transdermicamente absorvível contendo composto lípido-péptido BR112017015958A2 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2015-014772 2015-01-28
JP2015014772 2015-01-28
PCT/JP2016/052488 WO2016121867A1 (ja) 2015-01-28 2016-01-28 脂質ペプチド型化合物を含有する経皮吸収基材

Publications (1)

Publication Number Publication Date
BR112017015958A2 true BR112017015958A2 (pt) 2018-03-20

Family

ID=56543472

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112017015958-9A BR112017015958A2 (pt) 2015-01-28 2016-01-28 material de base transdermicamente absorvível contendo composto lípido-péptido

Country Status (7)

Country Link
US (3) US20180021250A1 (pt)
EP (1) EP3251696A4 (pt)
JP (2) JPWO2016121867A1 (pt)
KR (1) KR20170117438A (pt)
CN (1) CN107206095A (pt)
BR (1) BR112017015958A2 (pt)
WO (1) WO2016121867A1 (pt)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2865442B1 (en) * 2012-06-25 2017-12-06 Nissan Chemical Industries, Ltd. Liquid dispersion and formation method for hydrogels
CN107427440A (zh) * 2015-01-28 2017-12-01 国立大学法人九州大学 含有脂质肽型化合物的保湿基材
WO2016208442A1 (ja) * 2015-06-24 2016-12-29 日産化学工業株式会社 脂質ペプチド型化合物を含むスティック状基材
KR20190099208A (ko) * 2016-12-21 2019-08-26 닛산 가가쿠 가부시키가이샤 스틱상 피부외용 고형기재
CN110114061A (zh) * 2016-12-28 2019-08-09 小林制药株式会社 外用组合物
WO2018190383A1 (ja) * 2017-04-12 2018-10-18 日産化学株式会社 顔料又は粉体用分散剤を含有する分散液
EP3672565B1 (en) * 2017-12-30 2023-11-01 Colgate-Palmolive Company Personal care compositions
US20220002325A1 (en) * 2020-07-06 2022-01-06 Kemin Industries, Inc. Method for the preparation of lysophosphatidylinositol
JPWO2022092284A1 (pt) * 2020-10-30 2022-05-05

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5948855A (en) * 1999-01-12 1999-09-07 Dow Corning Corporation Water-in-oil-in water emulsion
WO2003061676A1 (en) 2002-01-25 2003-07-31 Mariana De Oliveira Compositions for and method of treatment for skin ailments
US8916682B2 (en) 2007-07-05 2014-12-23 Nissan Chemical Industries, Ltd. Lipid peptide and hydrogel
EP2180027B1 (en) 2007-07-05 2011-10-26 Nissan Chemical Industries, Ltd. Novel lipid-tripeptide based hydrogel-forming agent and hydrogel
JP2012518606A (ja) * 2009-02-20 2012-08-16 ディーエスエム アイピー アセッツ ビー．ブイ． 新規組成物
WO2011052613A1 (ja) * 2009-10-26 2011-05-05 日産化学工業株式会社 化粧料及び皮膚外用剤、並びに医療用機器
JP6516083B2 (ja) * 2013-06-05 2019-05-22 国立大学法人九州大学 経皮吸収基材

Also Published As

Publication number Publication date
US20180021250A1 (en) 2018-01-25
EP3251696A1 (en) 2017-12-06
US20190380949A1 (en) 2019-12-19
US11771645B2 (en) 2023-10-03
US11452688B2 (en) 2022-09-27
JP7011243B2 (ja) 2022-01-26
JPWO2016121867A1 (ja) 2017-11-02
KR20170117438A (ko) 2017-10-23
EP3251696A4 (en) 2018-09-05
JP2020164544A (ja) 2020-10-08
US20210401734A1 (en) 2021-12-30
WO2016121867A1 (ja) 2016-08-04
CN107206095A (zh) 2017-09-26

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Legal Events

Date Code Title Description
B07D Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]

Free format text: DE ACORDO COM O ARTIGO 229-C DA LEI NO 10196/2001, QUE MODIFICOU A LEI NO 9279/96, A CONCESSAO DA PATENTE ESTA CONDICIONADA A ANUENCIA PREVIA DA ANVISA. CONSIDERANDO A APROVACAO DOS TERMOS DO PARECER NO 337/PGF/EA/2010, BEM COMO A PORTARIA INTERMINISTERIAL NO 1065 DE 24/05/2012, ENCAMINHA-SE O PRESENTE PEDIDO PARA AS PROVIDENCIAS CABIVEIS.

B07E Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette]
B06U Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette]
B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B06G Technical and formal requirements: other requirements [chapter 6.7 patent gazette]
B06I Publication of requirement cancelled [chapter 6.9 patent gazette]

Free format text: ANULADA A PUBLICACAO CODIGO 6.7 NA RPI NO 2802 DE 17/09/2024 POR TER SIDO INDEVIDA.

B09B Patent application refused [chapter 9.2 patent gazette]